8CMH
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![BU of 8cmh by Molmil](/molmil-images/mine/8cmh) | Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Omicron (BA.1) Spike peptide S486-505 | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-ETHANETHIOL, HLA class II histocompatibility antigen, ... | Authors: | MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J. | Deposit date: | 2023-02-19 | Release date: | 2023-07-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity. Cell Rep, 42, 2023
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8CMC
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![BU of 8cmc by Molmil](/molmil-images/mine/8cmc) | Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Spike peptide S511-530 | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HLA class II histocompatibility antigen, ... | Authors: | MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J. | Deposit date: | 2023-02-19 | Release date: | 2023-07-26 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity. Cell Rep, 42, 2023
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8CMG
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![BU of 8cmg by Molmil](/molmil-images/mine/8cmg) | Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 nsp14 peptide (orf1ab)6420-6434 | Descriptor: | 1,2-ETHANEDIOL, HLA class II histocompatibility antigen, DR alpha chain, ... | Authors: | MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J. | Deposit date: | 2023-02-19 | Release date: | 2023-07-26 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity. Cell Rep, 42, 2023
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1JBO
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![BU of 1jbo by Molmil](/molmil-images/mine/1jbo) | The 1.45A Three-Dimensional Structure of c-Phycocyanin from the Thermophylic Cyanobacterium Synechococcus elongatus | Descriptor: | C-Phycocyanin alpha chain, C-Phycocyanin beta chain, PHYCOCYANOBILIN | Authors: | Nield, J, Rizkallah, P.J, Barber, J, Chayen, N.E. | Deposit date: | 2002-05-02 | Release date: | 2003-03-18 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The 1.45A three-dimensional structure of C-phycocyanin from the
thermophilic cyanobacterium Synechococcus elongatus J.STRUCT.BIOL., 141, 2003
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8CME
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![BU of 8cme by Molmil](/molmil-images/mine/8cme) | Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Membrane peptide M176-190 | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HLA class II histocompatibility antigen, ... | Authors: | MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J. | Deposit date: | 2023-02-19 | Release date: | 2023-07-26 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity. Cell Rep, 42, 2023
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8CMD
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![BU of 8cmd by Molmil](/molmil-images/mine/8cmd) | Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Spike peptide S761-775 | Descriptor: | 1,2-ETHANEDIOL, HLA class II histocompatibility antigen, DR alpha chain, ... | Authors: | MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J. | Deposit date: | 2023-02-19 | Release date: | 2023-07-26 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity. Cell Rep, 42, 2023
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4ZIN
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![BU of 4zin by Molmil](/molmil-images/mine/4zin) | Genetically encoded Phenyl Azide Photochemistry Drive Positive and Negative Functional Modulation of a Red Fluorescent Protein | Descriptor: | 1,2-ETHANEDIOL, MCherry fluorescent protein, SULFATE ION | Authors: | Reddington, S.C, Driezis, S, Hartley, A.M, Watson, P.D, Rizkallah, P.J, Jones, D.D. | Deposit date: | 2015-04-28 | Release date: | 2015-09-16 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Genetically encoded phenyl azide photochemistry drives positive and negative functional modulation of a red fluorescent protein Rsc Adv, 5, 2015
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4ZIO
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![BU of 4zio by Molmil](/molmil-images/mine/4zio) | Irradiated state of mCherry143azF | Descriptor: | SULFATE ION, mCherry | Authors: | Reddington, S.C, Driezis, S, Hartley, A.M, Watson, P.D, Rizkallah, P.J, Jones, D.D. | Deposit date: | 2015-04-28 | Release date: | 2015-09-16 | Last modified: | 2018-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Genetically encoded phenyl azide photochemistry drives positive and negative functional modulation of a red fluorescent protein Rsc Adv, 5, 2015
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5BS0
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![BU of 5bs0 by Molmil](/molmil-images/mine/5bs0) | MAGE-A3 Reactive TCR in complex with Titin Epitope in HLA-A1 | Descriptor: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | Authors: | Raman, M.C.C, Rizkallah, P.J, Simmons, R, Donellan, Z, Dukes, J, Bossi, G, LeProvost, G, Mahon, T, Hickman, E, Lomax, M, Oates, J, Hassan, N, Vuidepot, A, Sami, M, Cole, D.K, Jakobsen, B.K. | Deposit date: | 2015-06-01 | Release date: | 2016-03-02 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy. Sci Rep, 6, 2016
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1NPL
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![BU of 1npl by Molmil](/molmil-images/mine/1npl) | MANNOSE-SPECIFIC AGGLUTININ (LECTIN) FROM DAFFODIL (NARCISSUS PSEUDONARCISSUS) BULBS IN COMPLEX WITH MANNOSE-ALPHA1,3-MANNOSE | Descriptor: | PHOSPHATE ION, PROTEIN (AGGLUTININ), alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose | Authors: | Sauerborn, M.K, Wright, L.M, Reynolds, C.D, Grossmann, J.G, Rizkallah, P.J. | Deposit date: | 1998-12-17 | Release date: | 1998-12-23 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights into carbohydrate recognition by Narcissus pseudonarcissus lectin: the crystal structure at 2 A resolution in complex with alpha1-3 mannobiose. J.Mol.Biol., 290, 1999
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1FCU
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![BU of 1fcu by Molmil](/molmil-images/mine/1fcu) | CRYSTAL STRUCTURE (TRIGONAL) OF BEE VENOM HYALURONIDASE | Descriptor: | HYALURONOGLUCOSAMINIDASE | Authors: | Markovic-Housley, Z, Miglierini, G, Soldatova, L, Rizkallah, P.J, Mueller, U, Schirmer, T. | Deposit date: | 2000-07-19 | Release date: | 2001-10-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of hyaluronidase, a major allergen of bee venom. Structure Fold.Des., 8, 2000
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1FCV
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![BU of 1fcv by Molmil](/molmil-images/mine/1fcv) | CRYSTAL STRUCTURE OF BEE VENOM HYALURONIDASE IN COMPLEX WITH HYALURONIC ACID TETRAMER | Descriptor: | HYALURONOGLUCOSAMINIDASE, alpha-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranuronic acid | Authors: | Markovic-Housley, Z, Miglierini, G, Soldatova, L, Rizkallah, P.J, Mueller, U, Schirmer, T. | Deposit date: | 2000-07-19 | Release date: | 2001-10-01 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Crystal structure of hyaluronidase, a major allergen of bee venom. Structure Fold.Des., 8, 2000
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4GKN
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![BU of 4gkn by Molmil](/molmil-images/mine/4gkn) | A2-MHC Complex carrying FATGIGIITV | Descriptor: | Beta-2-microglobulin, FAT Cognate peptide, MHC class I antigen, ... | Authors: | Sewell, A.K, Rizkallah, P.J, Cole, D.K, Wooldridge, L, Price, D.A. | Deposit date: | 2012-08-13 | Release date: | 2012-09-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.753 Å) | Cite: | T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting. J.Biol.Chem., 287, 2012
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8PJE
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![BU of 8pje by Molmil](/molmil-images/mine/8pje) | Human Leukocyte Antigen class II allotype DR1 presenting influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAT | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | Authors: | MacLachlan, B.J, Wall, A, Greenshields-Watson, A.L, Hesketh, S.J, Cole, D.K, Rizkallah, P.J, Godkin, A.J. | Deposit date: | 2023-06-23 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation. Cell Rep, 43, 2024
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8PJF
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![BU of 8pjf by Molmil](/molmil-images/mine/8pjf) | Human Leukocyte Antigen class II allotype DR1 presenting P11T->R modified influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAR | Descriptor: | 1,2-ETHANEDIOL, HLA class II histocompatibility antigen, DR alpha chain, ... | Authors: | MacLachlan, B.J, Wall, A, Greenshields-Watson, A.L, Cole, D.K, Rizkallah, P.J, Godkin, A.J. | Deposit date: | 2023-06-23 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation. Cell Rep, 43, 2024
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8PJG
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![BU of 8pjg by Molmil](/molmil-images/mine/8pjg) | F11 TCR in complex with Human Leukocyte Antigen class II allotype DR1 presenting P11T->R modified influenza A virus haemagglutinin (HA)306-318 PKYVKQNTLKLAR | Descriptor: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, HLA class II histocompatibility antigen, ... | Authors: | MacLachlan, B.J, Wall, A, Greenshields-Watson, A.L, Cole, D.K, Rizkallah, P.J, Godkin, A.J. | Deposit date: | 2023-06-23 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4 + T cell activation. Cell Rep, 43, 2024
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5BTT
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![BU of 5btt by Molmil](/molmil-images/mine/5btt) | Switching GFP fluorescence using genetically encoded phenyl azide chemistry through two different non-native post-translational modifications routes at the same position. | Descriptor: | GLYCEROL, Green fluorescent protein, SULFATE ION | Authors: | Hartley, A.M, Worthy, H.L, Reddington, S.C, Rizkallah, P.J, Jones, D.D. | Deposit date: | 2015-06-03 | Release date: | 2016-07-13 | Last modified: | 2017-05-10 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Molecular basis for functional switching of GFP by two disparate non-native post-translational modifications of a phenyl azide reaction handle. Chem Sci, 7, 2016
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4GKS
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![BU of 4gks by Molmil](/molmil-images/mine/4gks) | A2-MHC Complex carrying FLTGIGIITV | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, FLT Cognate peptide, ... | Authors: | Sewell, A.K, Rizkallah, P.J, Cole, D.K, Wooldridge, L, Price, D.A. | Deposit date: | 2012-08-13 | Release date: | 2012-09-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.346 Å) | Cite: | T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting. J.Biol.Chem., 287, 2012
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4EUL
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![BU of 4eul by Molmil](/molmil-images/mine/4eul) | Crystal structure of enhanced Green Fluorescent Protein to 1.35A resolution reveals alternative conformations for Glu222 | Descriptor: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Green fluorescent protein, ... | Authors: | Jones, D.D, Arpino, J.A.J, Rizkallah, P.J. | Deposit date: | 2012-04-25 | Release date: | 2012-10-03 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Crystal structure of enhanced green fluorescent protein to 1.35 a resolution reveals alternative conformations for glu222. Plos One, 7, 2012
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6ZC5
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![BU of 6zc5 by Molmil](/molmil-images/mine/6zc5) | Human Adenovirus serotype D10 FiberKnob protein | Descriptor: | Fiber | Authors: | Baker, A.T, Mundy, R.M, Rizkallah, P.J, Parker, A.L. | Deposit date: | 2020-06-09 | Release date: | 2021-06-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Development of a low-seroprevalence, alpha v beta 6 integrin-selective virotherapy based on human adenovirus type 10. Mol Ther Oncolytics, 25, 2022
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8BXP
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![BU of 8bxp by Molmil](/molmil-images/mine/8bxp) | |
8C1X
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![BU of 8c1x by Molmil](/molmil-images/mine/8c1x) | |
4PHN
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![BU of 4phn by Molmil](/molmil-images/mine/4phn) | The Structural Basis of Differential Inhibition of Human Calpain by Indole and Phenyl alpha-Mercaptoacrylic Acids | Descriptor: | CALCIUM ION, Calpain small subunit 1 | Authors: | Allemann, R.K, Rizkallah, P.J, Adams, S.E, Miller, D.J, Hallett, M.B. | Deposit date: | 2014-05-06 | Release date: | 2014-08-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | The structural basis of differential inhibition of human calpain by indole and phenyl alpha-mercaptoacrylic acids. J.Struct.Biol., 187, 2014
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4PHJ
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![BU of 4phj by Molmil](/molmil-images/mine/4phj) | The Structural Basis of Differential Inhibition of Human Calpain by Indole and Phenyl alpha-Mercaptoacrylic Acids: Human unliganded protein | Descriptor: | CALCIUM ION, Calpain small subunit 1 | Authors: | Adams, S.E, Rizkallah, P.J, Allemann, R.K, Miller, D.J, Hallett, M.B, Robinson, E. | Deposit date: | 2014-05-06 | Release date: | 2014-08-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The structural basis of differential inhibition of human calpain by indole and phenyl alpha-mercaptoacrylic acids. J.Struct.Biol., 187, 2014
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4GKZ
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![BU of 4gkz by Molmil](/molmil-images/mine/4gkz) | HA1.7, a MHC class II restricted TCR specific for haemagglutinin | Descriptor: | 1,2-ETHANEDIOL, Alpha chain of Class II TCR, Beta Chain of Class II TCR, ... | Authors: | Holland, C.J, Rizkallah, P.J, Cole, D.K, Sewell, A.K, Godkin, A.J. | Deposit date: | 2012-08-13 | Release date: | 2012-11-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Minimal conformational plasticity enables TCR cross-reactivity to different MHC class II heterodimers. Sci Rep, 2, 2012
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