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PDB: 786 件

2JIG
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Crystal structure of Chlamydomonas reinhardtii prolyl-4 hydroxylase type I complexed with zinc and pyridine-2,4-dicarboxylate
分子名称: GLYCEROL, PROLYL-4 HYDROXYLASE, PYRIDINE-2,4-DICARBOXYLIC ACID, ...
著者Koski, M.K, Hieta, R, Bollner, C, Kivirikko, K.I, Myllyharju, J, Wierenga, R.K.
登録日2007-06-28
公開日2007-10-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The Active Site of an Algal Prolyl 4-Hydroxylase Has a Large Structural Plasticity.
J.Biol.Chem., 282, 2007
1W0V
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Crystal Structure Of HLA-B*2705 Complexed With the self-Peptide TIS from EGF-response factor 1
分子名称: BETA-2-MICROGLOBULIN, BUTYRATE RESPONSE FACTOR 2, GLYCEROL, ...
著者Hulsmeyer, M, Fiorillo, M.T, Bettosini, F, Sorrentino, R, Saenger, W, Ziegler, A, Uchanska-Ziegler, B.
登録日2004-06-14
公開日2005-03-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Thermodynamic and Structural Equivalence of Two Hla-B27 Subtypes Complexed with a Self-Peptide
J.Mol.Biol., 346, 2005
1SDL
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CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A
分子名称: 1,3,5-BENZENETRICARBOXYLIC ACID, CARBON MONOXIDE, HEMOGLOBIN A, ...
著者Schumacher, M.A, Dixon, M.M, Kluger, R, Jones, R.T, Brennan, R.G.
登録日1996-02-26
公開日1996-08-01
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Allosteric transition intermediates modelled by crosslinked haemoglobins.
Nature, 375, 1995
1SSG
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Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase
分子名称: 2-PHOSPHOGLYCOLIC ACID, GLYCEROL, SULFATE ION, ...
著者Kursula, I, Salin, M, Sun, J, Norledge, B.V, Haapalainen, A.M, Sampson, N.S, Wierenga, R.K.
登録日2004-03-24
公開日2004-08-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase
Protein Eng.Des.Sel., 17, 2004
1BDH
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PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
分子名称: DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR)
著者Glasfeld, A, Schumacher, M.A, Choi, K.Y, Zalkin, H, Brennan, R.G.
登録日1996-07-25
公開日1997-04-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A Positively Charged Residue Bound in the Minor Groove Does not Alter the Bending of a DNA Duplex
J.Am.Chem.Soc., 118, 1996
1BDI
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PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX
分子名称: DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T )-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR)
著者Glasfeld, A, Schumacher, M.A, Choi, K.Y, Zalkin, H, Brennan, R.G.
登録日1996-07-25
公開日1997-04-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A Positively Charged Residue Bound in the Minor Groove Does not Alter the Bending of a DNA Duplex
J.Am.Chem.Soc., 118, 1996
1JT6
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Crystal structure of the multidrug binding protein QacR bound to dequalinium
分子名称: DEQUALINIUM, Hypothetical transcriptional regulator IN QACA 5'region, SULFATE ION
著者Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G.
登録日2001-08-20
公開日2001-12-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structural mechanisms of QacR induction and multidrug recognition.
Science, 294, 2001
2IB8
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Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acetyl-CoA acetyltransferase, CHLORIDE ION, ...
著者Haapalainen, A.M, Wierenga, R.K.
登録日2006-09-11
公開日2007-04-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-CoA Thiolase: The Importance of Potassium and Chloride Ions for Its Structure and Function
Biochemistry, 46, 2007
1SW0
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Triosephosphate isomerase from Gallus gallus, loop 6 hinge mutant K174L, T175W
分子名称: 2-PHOSPHOGLYCOLIC ACID, Triosephosphate isomerase
著者Kursula, I, Salin, M, Sun, J, Norledge, B.V, Haapalainen, A.M, Sampson, N.S, Wierenga, R.K.
登録日2004-03-30
公開日2004-08-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase
Protein Eng.Des.Sel., 17, 2004
1SW3
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Triosephosphate isomerase from Gallus gallus, loop 6 mutant T175V
分子名称: 2-PHOSPHOGLYCOLIC ACID, Triosephosphate isomerase
著者Kursula, I, Salin, M, Sun, J, Norledge, B.V, Haapalainen, A.M, Sampson, N.S, Wierenga, R.K.
登録日2004-03-30
公開日2004-08-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase
Protein Eng.Des.Sel., 17, 2004
1BD4
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UPRT-URACIL COMPLEX
分子名称: PHOSPHATE ION, URACIL, URACIL PHOSPHORIBOSYLTRANSFERASE
著者Schumacher, M.A, Carter, D, Scott, D, Roos, D, Ullman, B, Brennan, R.G.
登録日1998-05-12
公開日1999-05-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
EMBO J., 17, 1998
1JLS
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STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE URACIL/CPR 2 MUTANT C128V
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, PHOSPHATE ION, ...
著者Schumacher, M.A, Bashor, C.J, Otsu, K, Zu, S, Parry, R, Ullman, B, Brennan, R.G.
登録日2001-07-16
公開日2002-01-16
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferase.
Proc.Natl.Acad.Sci.USA, 99, 2002
1JTX
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Crystal structure of the multidrug binding transcriptional regulator QacR bound to crystal violet
分子名称: CRYSTAL VIOLET, HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, SULFATE ION
著者Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G.
登録日2001-08-22
公開日2001-12-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural mechanisms of QacR induction and multidrug recognition.
Science, 294, 2001
2IBU
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Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function
分子名称: Acetyl-CoA acetyltransferase, CHLORIDE ION, COENZYME A, ...
著者Haapalainen, A.M, Wierenga, R.K.
登録日2006-09-12
公開日2007-04-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-CoA Thiolase: The Importance of Potassium and Chloride Ions for Its Structure and Function
Biochemistry, 46, 2007
2IBW
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Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase (T2): the importance of potassium and chloride for its structure and function
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acetyl-CoA acetyltransferase, CHLORIDE ION, ...
著者Haapalainen, A.M, Wierenga, R.K.
登録日2006-09-12
公開日2007-04-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystallographic and Kinetic Studies of Human Mitochondrial Acetoacetyl-CoA Thiolase: The Importance of Potassium and Chloride Ions for Its Structure and Function
Biochemistry, 46, 2007
1PXT
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THE 2.8 ANGSTROMS STRUCTURE OF PEROXISOMAL 3-KETOACYL-COA THIOLASE OF SACCHAROMYCES CEREVISIAE: A FIVE LAYERED A-B-A-B-A STRUCTURE, CONSTRUCTED FROM TWO CORE DOMAINS OF IDENTICAL TOPOLOGY
分子名称: PEROXISOMAL 3-KETOACYL-COA THIOLASE
著者Mathieu, M, Wierenga, R.K.
登録日1994-07-04
公開日1994-08-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The 2.8 A crystal structure of peroxisomal 3-ketoacyl-CoA thiolase of Saccharomyces cerevisiae: a five-layered alpha beta alpha beta alpha structure constructed from two core domains of identical topology.
Structure, 2, 1994
1SDK
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CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A
分子名称: 1,3,5-BENZENETRICARBOXYLIC ACID, CARBON MONOXIDE, HEMOGLOBIN A, ...
著者Schumacher, M.A, Dixon, M.M, Kluger, R, Jones, R.T, Brennan, R.G.
登録日1996-02-26
公開日1996-08-01
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Allosteric transition intermediates modelled by crosslinked haemoglobins.
Nature, 375, 1995
2HIS
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CELLULOMONAS FIMI XYLANASE/CELLULASE DOUBLE MUTANT E127A/H205N WITH COVALENT CELLOBIOSE
分子名称: CELLULOMONAS FIMI FAMILY 10 BETA-1,4-GLYCANASE, beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Notenboom, V, Birsan, C, Nitz, M, Rose, D.R, Warren, R.A.J, Wither, S.G.
登録日1998-02-23
公開日1998-10-14
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Insights into transition state stabilization of the beta-1,4-glycosidase Cex by covalent intermediate accumulation in active site mutants.
Nat.Struct.Biol., 5, 1998
1RZR
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crystal structure of transcriptional regulator-phosphoprotein-DNA complex
分子名称: 5'-D(*CP*TP*GP*AP*AP*AP*GP*CP*GP*CP*TP*AP*AP*CP*AP*G)-3', 5'-D(*CP*TP*GP*TP*TP*AP*GP*CP*GP*CP*TP*TP*TP*CP*AP*G)-3', Glucose-resistance amylase regulator, ...
著者Schumacher, M.A, Allen, G.S, Brennan, R.G.
登録日2003-12-27
公開日2004-10-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for allosteric control of the transcription regulator CcpA by the phosphoprotein HPr-Ser46-P.
Cell(Cambridge,Mass.), 118, 2004
1JTY
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Crystal structure of the multidrug binding transcriptional regulator QacR bound to ethidium
分子名称: ETHIDIUM, HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, SULFATE ION
著者Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G.
登録日2001-08-22
公開日2001-12-12
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Structural mechanisms of QacR induction and multidrug recognition.
Science, 294, 2001
1JUM
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Crystal structure of the multidrug binding transcriptional repressor QacR bound to the natural drug berberine
分子名称: BERBERINE, HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN QACA 5'REGION, SULFATE ION
著者Schumacher, M.A, Miller, M.C, Grkovic, S, Brown, M.H, Skurray, R.A, Brennan, R.G.
登録日2001-08-24
公開日2001-12-12
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Structural mechanisms of QacR induction and multidrug recognition.
Science, 294, 2001
1SPQ
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Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase
分子名称: DI(HYDROXYETHYL)ETHER, Triosephosphate isomerase
著者Kursula, I, Salin, M, Sun, J, Norledge, B.V, Haapalainen, A.M, Sampson, N.S, Wierenga, R.K.
登録日2004-03-17
公開日2004-08-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase
Protein Eng.Des.Sel., 17, 2004
1SQ7
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Understanding protein lids: Structural analysis of active hinge mutants in triosephosphate isomerase
分子名称: Triosephosphate isomerase
著者Kursula, I, Salin, M, Sun, J, Norledge, B.V, Haapalainen, A.M, Sampson, N.S, Wierenga, R.K.
登録日2004-03-18
公開日2004-08-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Understanding protein lids: structural analysis of active hinge mutants in triosephosphate isomerase
Protein Eng.Des.Sel., 17, 2004
1JLR
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STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE GTP COMPLEX 2 MUTANT C128V
分子名称: GUANOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, Uracil Phosphoribosyltransferase
著者Schumacher, M.A, Bashor, C.J, Otsu, K, Zu, S, Parry, R, Ulmman, B, Brennan, R.G.
登録日2001-07-16
公開日2002-01-10
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The structural mechanism of GTP stabilized oligomerization and catalytic activation of the Toxoplasma gondii uracil phosphoribosyltransferase.
Proc.Natl.Acad.Sci.USA, 99, 2002
5U51
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Structure of Francisella tularensis heterodimeric SspA (MglA-SspA) in complex with ppGpp
分子名称: GLYCEROL, GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION, ...
著者Cuthbert, B.J, Schumacher, M.A, Brennan, R.G.
登録日2016-12-06
公開日2017-08-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Dissection of the molecular circuitry controlling virulence in Francisella tularensis.
Genes Dev., 31, 2017

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