7SIZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7siz by Molmil](/molmil-images/mine/7siz) | C-type inactivation in a voltage gated K+ channel | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, Voltage gated potassium channel Kv1.2-Kv2.1, ... | Authors: | Reddi, R, Riederer, E.A, Matulef, K, Whorton, M.R, Valiyaveetil, F.I. | Deposit date: | 2021-10-15 | Release date: | 2022-05-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis for C-type inactivation in a Shaker family voltage-gated K + channel. Sci Adv, 8, 2022
|
|
7SIT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sit by Molmil](/molmil-images/mine/7sit) | Crystal structure of Voltage gated potassium ion channel, Kv 1.2 chimera-3m | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, OXYGEN ATOM, POTASSIUM ION, ... | Authors: | Reddi, R, Matulef, K, Riederer, E.A, Whorton, M.R, Valiyaveetil, F.I. | Deposit date: | 2021-10-14 | Release date: | 2022-05-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.32 Å) | Cite: | Structural basis for C-type inactivation in a Shaker family voltage-gated K + channel. Sci Adv, 8, 2022
|
|
4X5K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4x5k by Molmil](/molmil-images/mine/4x5k) | |
7RP0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7rp0 by Molmil](/molmil-images/mine/7rp0) | Structural Snapshots of Intermediates in the Gating of a K+ Channel | Descriptor: | DIACYL GLYCEROL, KcsA Fab chain A, KcsA Fab chain B, ... | Authors: | Reddi, R, Matulef, K, Riederer, E.A, Valiyaveetil, F.I. | Deposit date: | 2021-08-02 | Release date: | 2021-10-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Structures of Gating Intermediates in a K + channell. J.Mol.Biol., 433, 2021
|
|
8THN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8thn by Molmil](/molmil-images/mine/8thn) | KcsA M96V mutant with Y78ester in High K+ | Descriptor: | KcsA Fab Heavy Chain, KcsA Fab Light Chain, POTASSIUM ION, ... | Authors: | Reddi, R, Valiyaveetil, F.I. | Deposit date: | 2023-07-17 | Release date: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A facile approach for incorporating tyrosine esters to probe ion-binding sites and backbone hydrogen bonds. J.Biol.Chem., 300, 2023
|
|
4OOK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ook by Molmil](/molmil-images/mine/4ook) | Third Metal bound M.tuberculosis methionine aminopeptidase | Descriptor: | COBALT (II) ION, Methionine aminopeptidase 2, SODIUM ION | Authors: | Reddi, R, Addlagatta, A. | Deposit date: | 2014-02-03 | Release date: | 2015-02-04 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents Febs J., 281, 2014
|
|
4Q4E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4q4e by Molmil](/molmil-images/mine/4q4e) | Crystal structure of E.coli aminopeptidase N in complex with actinonin | Descriptor: | ACTINONIN, Aminopeptidase N, GLYCEROL, ... | Authors: | Reddi, R, Ganji, R.J, Addlagatta, A. | Deposit date: | 2014-04-14 | Release date: | 2015-04-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for the inhibition of M1 family aminopeptidases by the natural product actinonin: Crystal structure in complex with E. coli aminopeptidase N. Protein Sci., 24, 2015
|
|
4Q4I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4q4i by Molmil](/molmil-images/mine/4q4i) | Crystal structure of E.coli aminopeptidase N in complex with amastatin | Descriptor: | Amastatin, Aminopeptidase N, GLYCEROL, ... | Authors: | Reddi, R, Ganji, R.J, Addlagatta, A. | Deposit date: | 2014-04-14 | Release date: | 2015-04-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Structural basis for the inhibition of M1 family aminopeptidases by the natural product actinonin: Crystal structure in complex with E. coli aminopeptidase N. Protein Sci., 24, 2015
|
|
8DHR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dhr by Molmil](/molmil-images/mine/8dhr) | An ester mutant of SfGFP | Descriptor: | Green fluorescent protein | Authors: | Reddi, R, Valiyaveetil, F.I. | Deposit date: | 2022-06-28 | Release date: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | A facile approach for incorporating tyrosine esters to probe ion-binding sites and backbone hydrogen bonds. J.Biol.Chem., 300, 2023
|
|
3ROR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ror by Molmil](/molmil-images/mine/3ror) | |
7M2H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7m2h by Molmil](/molmil-images/mine/7m2h) | |
7M2J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7m2j by Molmil](/molmil-images/mine/7m2j) | |
7M2I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7m2i by Molmil](/molmil-images/mine/7m2i) | |
4IDY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4idy by Molmil](/molmil-images/mine/4idy) | Mycobacterium Tuberculosis Methionine aminopeptidase Type 1c in complex with 2-hydroxyethyl disulfide | Descriptor: | 2-HYDROXYETHYL DISULFIDE, Methionine aminopeptidase 2, POTASSIUM ION | Authors: | Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A. | Deposit date: | 2012-12-13 | Release date: | 2013-12-18 | Last modified: | 2015-02-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents Febs J., 281, 2014
|
|
4IF7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4if7 by Molmil](/molmil-images/mine/4if7) | Mycobacterium Tuberculosis Methionine aminopeptidase Type 1c in complex with homocysteine-methyl disulfide | Descriptor: | (2S)-2-amino-4-(methyldisulfanyl)butanoic acid, COBALT (II) ION, Methionine aminopeptidase 2 | Authors: | Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A. | Deposit date: | 2012-12-14 | Release date: | 2013-12-18 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents Febs J., 281, 2014
|
|
4IEC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4iec by Molmil](/molmil-images/mine/4iec) | Cys105 covalent modification by 2-hydroxyethyl disulfide in Mycobacterium tuberculosis methionine aminopeptidase Type 1c | Descriptor: | COBALT (II) ION, Methionine aminopeptidase 2, POTASSIUM ION | Authors: | Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A. | Deposit date: | 2012-12-13 | Release date: | 2013-12-18 | Last modified: | 2019-11-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents Febs J., 281, 2014
|
|
3TB5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tb5 by Molmil](/molmil-images/mine/3tb5) | Crystal Structure of the Enterococcus faecalis Methionine aminopeptidase apo form | Descriptor: | CITRIC ACID, Methionine aminopeptidase | Authors: | Kishor, C, Gumpena, R, Reddi, R, Addlagatta, A. | Deposit date: | 2011-08-05 | Release date: | 2012-08-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural studies of Enterococcus faecalis methionine aminopeptidase and design of microbe specific 2,2'-bipyridine based inhibitors MEDCHEMCOMM, 3, 2012
|
|
5YQB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yqb by Molmil](/molmil-images/mine/5yqb) | Crystal structure of E.coli aminopeptidase N in complex with Puromycin | Descriptor: | (2R,3R,4S,5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL, Aminopeptidase N, GLYCEROL, ... | Authors: | Marapaka, A.K, Ganji, R.J, Reddi, R, Addlagatta, A. | Deposit date: | 2017-11-06 | Release date: | 2018-11-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis Int.J.Biol.Macromol., 165, 2020
|
|
5YO1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yo1 by Molmil](/molmil-images/mine/5yo1) | Structure of ePepN E298A mutant in complex with Puromycin | Descriptor: | Aminopeptidase N, GLYCEROL, PUROMYCIN, ... | Authors: | Ganji, R.J, Reddi, R, Marapaka, A.K, Addlagatta, A. | Deposit date: | 2017-10-26 | Release date: | 2018-11-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis Int.J.Biol.Macromol., 165, 2020
|
|
5YQ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yq1 by Molmil](/molmil-images/mine/5yq1) | Crystal structure of E.coli aminopeptidase N in complex with O-Methyl-L-tyrosine | Descriptor: | Aminopeptidase N, GLYCEROL, MALONATE ION, ... | Authors: | Marapaka, A.K, Ganji, R.J, Reddi, R, Addlagatta, A. | Deposit date: | 2017-11-04 | Release date: | 2018-11-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Crystal structure of E.coli aminopeptidase N in complex with O-Methyl-L-tyrosine To Be Published
|
|
5YQ2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yq2 by Molmil](/molmil-images/mine/5yq2) | Crystal structure of E.coli aminopeptidase N in complex with Puromycin aminonucleoside | Descriptor: | (2R,3R,4S,5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL, Aminopeptidase N, GLYCEROL, ... | Authors: | Marapaka, A.K, Ganji, R.J, Reddi, R, Addlagatta, A. | Deposit date: | 2017-11-04 | Release date: | 2018-11-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of E.coli aminopeptidase N in complex with Puromycin aminonucleoside To Be Published
|
|