7QJJ
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![BU of 7qjj by Molmil](/molmil-images/mine/7qjj) | X-Ray Structure of a Mn2+ soak of EleNRMT in complex with two Nanobodies at 4.6A | Descriptor: | Divalent metal cation transporter, Elen-Nb1-Nb2, MANGANESE (II) ION | Authors: | Ramanadane, K, Straub, M.S, Dutzler, R, Manatschal, C. | Deposit date: | 2021-12-16 | Release date: | 2022-02-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (4.6 Å) | Cite: | Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family. Elife, 11, 2022
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2XBU
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![BU of 2xbu by Molmil](/molmil-images/mine/2xbu) | Saccharomyces cerevisiae hypoxanthine-guanine phosphoribosyltransferase in complex with GMP (monoclinic crystal form) | Descriptor: | ACETATE ION, GUANOSINE-5'-MONOPHOSPHATE, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, ... | Authors: | Moynie, L, Giraud, M.F, Breton, A, Boissier, F, Daignan-Fornier, B, Dautant, A. | Deposit date: | 2010-04-15 | Release date: | 2011-05-04 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Functional Significance of Four Successive Glycine Residues in the Pyrophosphate Binding Loop of Fungal 6-Oxopurine Phosphoribosyltransferases. Protein Sci., 21, 2012
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2HUR
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![BU of 2hur by Molmil](/molmil-images/mine/2hur) | Escherichia coli nucleoside diphosphate kinase | Descriptor: | NUCLEOSIDE DIPHOSPHATE KINASE, SULFATE ION | Authors: | Moynie, L, Giraud, M.-F, Georgescauld, F, Lascu, I, Dautant, A. | Deposit date: | 2006-07-27 | Release date: | 2007-04-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | The structure of the Escherichia coli nucleoside diphosphate kinase reveals a new quaternary architecture for this enzyme family Proteins, 67, 2007
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1ACF
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![BU of 1acf by Molmil](/molmil-images/mine/1acf) | ACANTHAMOEBA CASTELLANII PROFILIN IB | Descriptor: | PROFILIN I | Authors: | Fedorov, A.A, Magnus, K.A, Graupe, M.H, Lattman, E.E, Pollard, T.D, Almo, S.C. | Deposit date: | 1994-07-29 | Release date: | 1994-08-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structures of isoforms of the actin-binding protein profilin that differ in their affinity for phosphatidylinositol phosphates. Proc.Natl.Acad.Sci.USA, 91, 1994
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1RM8
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![BU of 1rm8 by Molmil](/molmil-images/mine/1rm8) | Crystal structure of the catalytic domain of MMP-16/MT3-MMP: Characterization of MT-MMP specific features | Descriptor: | 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, CALCIUM ION, Matrix metalloproteinase-16, ... | Authors: | Lang, R, Braun, M, Sounni, N.E, Noel, A, Frankenne, F, Foidart, J.-M, Bode, W, Maskos, K. | Deposit date: | 2003-11-27 | Release date: | 2004-03-09 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the catalytic domain of MMP-16/MT3-MMP: characterization of MT-MMP specific features. J.Mol.Biol., 336, 2004
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2ACG
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![BU of 2acg by Molmil](/molmil-images/mine/2acg) | ACANTHAMOEBA CASTELLANII PROFILIN II | Descriptor: | PROFILIN II | Authors: | Fedorov, A.A, Magnus, K.A, Graupe, M.H, Lattman, E.E, Pollard, T.D, Almo, S.C. | Deposit date: | 1994-08-30 | Release date: | 1994-11-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-ray structures of isoforms of the actin-binding protein profilin that differ in their affinity for phosphatidylinositol phosphates. Proc.Natl.Acad.Sci.USA, 91, 1994
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2X7O
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![BU of 2x7o by Molmil](/molmil-images/mine/2x7o) | Crystal structure of TGFbRI complexed with an indolinone inhibitor | Descriptor: | (3Z)-N-ETHYL-N-METHYL-2-OXO-3-(PHENYL{[4-(PIPERIDIN-1-YLMETHYL)PHENYL]AMINO}METHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-6-CARBOXAMIDE, TGF-BETA RECEPTOR TYPE I | Authors: | Roth, G.J, Heckel, A, Brandl, T, Grauert, M, Hoerer, S, Kley, J.T, Schnapp, G, Baum, P, Mennerich, D, Schnapp, A, Park, J.E. | Deposit date: | 2010-03-03 | Release date: | 2010-10-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Design, Synthesis and Evaluation of Indolinones as Inhibitors of the Transforming Growth Factor Beta Receptor I (Tgfbri) J.Med.Chem., 53, 2010
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6SOF
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![BU of 6sof by Molmil](/molmil-images/mine/6sof) | human insulin receptor ectodomain bound by 4 insulin | Descriptor: | Insulin, Insulin receptor | Authors: | Gutmann, T, Schaefer, I.B, Poojari, C.S, Vattulainen, I, Strauss, M, Coskun, U. | Deposit date: | 2019-08-29 | Release date: | 2019-11-13 | Last modified: | 2020-05-27 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain. J.Cell Biol., 219, 2020
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3A1M
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![BU of 3a1m by Molmil](/molmil-images/mine/3a1m) | A fusion protein of a beta helix region of gene product 5 and the foldon region of bacteriophage T4 | Descriptor: | POTASSIUM ION, chimera of thrombin cleavage site, Tail-associated lysozyme, ... | Authors: | Yokoi, N, Suzuki, A, Hikage, T, Koshiyama, T, Terauchi, M, Yutani, K, Kanamaru, S, Arisaka, F, Yamane, T, Watanabe, Y, Ueno, T. | Deposit date: | 2009-04-11 | Release date: | 2010-04-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Construction of Robust Bio-nanotubes using the Controlled Self-Assembly of Component Proteins of Bacteriophage T4 Small, 6, 2010
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5C8B
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![BU of 5c8b by Molmil](/molmil-images/mine/5c8b) | |
3H1Z
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![BU of 3h1z by Molmil](/molmil-images/mine/3h1z) | Molecular basis for the association of PIPKIgamma -p90 with the clathrin adaptor AP-2 | Descriptor: | AP-2 complex subunit beta-1, Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma | Authors: | Vahedi-Faridi, A, Kahlfeldt, N, Schaefer, J.G, Krainer, G, Keller, S, Saenger, W, Krauss, M, Haucke, V. | Deposit date: | 2009-04-14 | Release date: | 2009-11-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Molecular basis for association of PIPKI gamma-p90 with clathrin adaptor AP-2. J.Biol.Chem., 285, 2010
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1JK3
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![BU of 1jk3 by Molmil](/molmil-images/mine/1jk3) | Crystal structure of human MMP-12 (Macrophage Elastase) at true atomic resolution | Descriptor: | 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, CALCIUM ION, MACROPHAGE METALLOELASTASE, ... | Authors: | Lang, R, Kocourek, A, Braun, M, Tschesche, H, Huber, R, Bode, W, Maskos, K. | Deposit date: | 2001-07-11 | Release date: | 2001-09-28 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | Substrate specificity determinants of human macrophage elastase (MMP-12) based on the 1.1 A crystal structure. J.Mol.Biol., 312, 2001
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1T46
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![BU of 1t46 by Molmil](/molmil-images/mine/1t46) | STRUCTURAL BASIS FOR THE AUTOINHIBITION AND STI-571 INHIBITION OF C-KIT TYROSINE KINASE | Descriptor: | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, PHOSPHATE ION | Authors: | Mol, C.D, Dougan, D.R, Schneider, T.R, Skene, R.J, Kraus, M.L, Scheibe, D.N, Snell, G.P, Zou, H, Sang, B.C, Wilson, K.P. | Deposit date: | 2004-04-28 | Release date: | 2004-06-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase. J.Biol.Chem., 279, 2004
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1T45
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![BU of 1t45 by Molmil](/molmil-images/mine/1t45) | STRUCTURAL BASIS FOR THE AUTOINHIBITION AND STI-571 INHIBITION OF C-KIT TYROSINE KINASE | Descriptor: | Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | Authors: | Mol, C.D, Dougan, D.R, Schneider, T.R, Skene, R.J, Kraus, M.L, Scheibe, D.N, Snell, G.P, Zou, H, Sang, B.C, Wilson, K.P. | Deposit date: | 2004-04-28 | Release date: | 2004-06-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase. J.Biol.Chem., 279, 2004
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6FME
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![BU of 6fme by Molmil](/molmil-images/mine/6fme) | |