1Y2M
 
 | | Crystal structure of phenylalanine ammonia-lyase from yeast Rhododporidium toruloides | | 分子名称: | Phenylalanine ammonia-lyase | | 著者 | Wang, L, Gamez, A, Sarkissian, C.N, Straub, M, Patch, M.G, Han, G.W, Scriver, C.R, Stevens, R.C. | | 登録日 | 2004-11-22 | | 公開日 | 2005-11-01 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure-based chemical modification strategy for enzyme replacement treatment of phenylketonuria.
Mol.Genet.Metab., 86, 2005
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1KET
 | | The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Streptococcus suis with thymidine diphosphate bound | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, THYMIDINE-5'-DIPHOSPHATE, dTDP-D-glucose 4,6-dehydratase | | 著者 | Allard, S.T.M, Beis, K, Giraud, M.-F, Hegeman, A.D, Gross, J.W, Whitfield, C, Graninger, M, Messner, P, Allen, A.G, Naismith, J.H. | | 登録日 | 2001-11-17 | | 公開日 | 2002-01-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Toward a structural understanding of the dehydratase mechanism.
Structure, 10, 2002
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1Z68
 | | Crystal Structure Of Human Fibroblast Activation Protein alpha | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Aertgeerts, K, Levin, I, Shi, L, Prasad, G.S, Zhang, Y, Kraus, M.L, Salakian, S, Snell, G.P, Sridhar, V, Wijnands, R, Tennant, M.G. | | 登録日 | 2005-03-21 | | 公開日 | 2005-04-12 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha.
J.Biol.Chem., 280, 2005
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1KEP
 | | The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Streptococcus suis with dTDP-xylose bound | | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, THYMIDINE-5'-DIPHOSPHO-BETA-D-XYLOSE, ... | | 著者 | Allard, S.T.M, Beis, K, Giraud, M.-F, Hegeman, A.D, Gross, J.W, Whitfield, C, Graninger, M, Messner, P, Allen, A.G, Naismith, J.H. | | 登録日 | 2001-11-16 | | 公開日 | 2002-01-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Toward a structural understanding of the dehydratase mechanism.
Structure, 10, 2002
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1KEW
 | | The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar Typhimurium with thymidine diphosphate bound | | 分子名称: | GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, THYMIDINE-5'-DIPHOSPHATE, ... | | 著者 | Allard, S.T.M, Beis, K, Giraud, M.-F, Hegeman, A.D, Gross, J.W, Whitfield, C, Graninger, M, Messner, P, Allen, A.G, Naismith, J.H. | | 登録日 | 2001-11-17 | | 公開日 | 2002-01-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Toward a structural understanding of the dehydratase mechanism.
Structure, 10, 2002
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2RO4
 | | RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator AbrB | | 分子名称: | Transition state regulatory protein abrB | | 著者 | Sullivan, D.M, Bobay, B.G, Kojetin, D.J, Thompson, R.J, Rance, M, Strauch, M.A, Cavanagh, J. | | 登録日 | 2008-03-08 | | 公開日 | 2008-11-11 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Insights into the nature of DNA binding of AbrB-like transcription factors
Structure, 16, 2008
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1KER
 | | The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Streptococcus suis with dTDP-D-glucose bound | | 分子名称: | 2'DEOXY-THYMIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... | | 著者 | Allard, S.T.M, Beis, K, Giraud, M.-F, Hegeman, A.D, Gross, J.W, Whitfield, C, Graninger, M, Messner, P, Allen, A.G, Naismith, J.H. | | 登録日 | 2001-11-17 | | 公開日 | 2002-01-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Toward a structural understanding of the dehydratase mechanism.
Structure, 10, 2002
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2RO3
 | | RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator Abh | | 分子名称: | Putative transition state regulator abh | | 著者 | Sullivan, D.M, Bobay, B.G, Douglas, K.J, Thompson, R.J, Rance, M, Strauch, M.A, Cavanagh, J. | | 登録日 | 2008-03-08 | | 公開日 | 2008-11-11 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Insights into the nature of DNA binding of AbrB-like transcription factors
Structure, 16, 2008
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2RO5
 | | RDC-refined solution structure of the N-terminal DNA recognition domain of the Bacillus subtilis transition-state regulator SpoVT | | 分子名称: | Stage V sporulation protein T | | 著者 | Sullivan, D.M, Bobay, B.G, Kojetin, D.J, Thompson, R.J, Rance, M, Strauch, M.A, Cavanagh, J. | | 登録日 | 2008-03-08 | | 公開日 | 2008-11-11 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Insights into the nature of DNA binding of AbrB-like transcription factors
Structure, 16, 2008
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7QIA
 | | Structure of apo-EleNRMT in complex with two nanobodies at 3.5A | | 分子名称: | Divalent metal cation transporter, Nanobody 1, Nanobody 2 | | 著者 | Ramanadane, K, Straub, M.S, Dutzler, R, Manatschal, C. | | 登録日 | 2021-12-14 | | 公開日 | 2021-12-29 | | 最終更新日 | 2022-02-02 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family.
Elife, 11, 2022
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7QIC
 | | Structure of magnesium-bound EleNRMT in complex with two nanobodies at 4.1A | | 分子名称: | Divalent metal cation transporter, MAGNESIUM ION, Nanobody 1, ... | | 著者 | Ramanadane, K, Straub, M.S, Dutzler, R, Manatschal, C. | | 登録日 | 2021-12-14 | | 公開日 | 2021-12-29 | | 最終更新日 | 2022-02-02 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family.
Elife, 11, 2022
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3A1M
 | | A fusion protein of a beta helix region of gene product 5 and the foldon region of bacteriophage T4 | | 分子名称: | POTASSIUM ION, chimera of thrombin cleavage site, Tail-associated lysozyme, ... | | 著者 | Yokoi, N, Suzuki, A, Hikage, T, Koshiyama, T, Terauchi, M, Yutani, K, Kanamaru, S, Arisaka, F, Yamane, T, Watanabe, Y, Ueno, T. | | 登録日 | 2009-04-11 | | 公開日 | 2010-04-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Construction of Robust Bio-nanotubes using the Controlled Self-Assembly of Component Proteins of Bacteriophage T4
Small, 6, 2010
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7QID
 | | tentative model of the human insulin receptor ectodomain bound by three insulin | | 分子名称: | Insulin, Insulin receptor, Isoform Short of Insulin receptor | | 著者 | Gutman, T, Schaefer, I.B, Poojari, C.S, Vattulainen, I, Strauss, M, Coskun, U. | | 登録日 | 2021-12-14 | | 公開日 | 2022-02-02 | | 実験手法 | ELECTRON MICROSCOPY (5 Å) | | 主引用文献 | Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain
J Cell Biol, 219, 2020
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7QJI
 | | X-Ray Structure of apo-EleNRMT in complex with two Nanobodies at 4.1A | | 分子名称: | Divalent metal cation transporter, Elen-Nanobody-complex | | 著者 | Ramanadane, K, Straub, M.S, Dutzler, R, Manatschal, C. | | 登録日 | 2021-12-16 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | | 主引用文献 | Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family.
Elife, 11, 2022
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7QJJ
 | | X-Ray Structure of a Mn2+ soak of EleNRMT in complex with two Nanobodies at 4.6A | | 分子名称: | Divalent metal cation transporter, Elen-Nb1-Nb2, MANGANESE (II) ION | | 著者 | Ramanadane, K, Straub, M.S, Dutzler, R, Manatschal, C. | | 登録日 | 2021-12-16 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (4.6 Å) | | 主引用文献 | Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family.
Elife, 11, 2022
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3J9I
 | | Thermoplasma acidophilum 20S proteasome | | 分子名称: | Proteasome subunit alpha, Proteasome subunit beta | | 著者 | Li, X, Mooney, P, Zheng, S, Booth, C, Braunfeld, M.B, Gubbens, S, Agard, D.A, Cheng, Y. | | 登録日 | 2015-02-02 | | 公開日 | 2015-02-18 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM.
Nat.Methods, 10, 2013
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5MAN
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2XBU
 | | Saccharomyces cerevisiae hypoxanthine-guanine phosphoribosyltransferase in complex with GMP (monoclinic crystal form) | | 分子名称: | ACETATE ION, GUANOSINE-5'-MONOPHOSPHATE, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, ... | | 著者 | Moynie, L, Giraud, M.F, Breton, A, Boissier, F, Daignan-Fornier, B, Dautant, A. | | 登録日 | 2010-04-15 | | 公開日 | 2011-05-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Functional Significance of Four Successive Glycine Residues in the Pyrophosphate Binding Loop of Fungal 6-Oxopurine Phosphoribosyltransferases.
Protein Sci., 21, 2012
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8JFC
 | | V1/S quadruple mutant Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with compound 6 (B21591), NADPH and dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 4-[3-[[2,4-bis(azanyl)-6-ethyl-pyrimidin-5-yl]methyl]phenyl]benzoic acid, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | | 著者 | Vanichtanankul, J, Saeyang, T, Vitsupakorn, D, Saepua, S, Thongpanchang, C, Yuthavong, Y, Kamchonwongpaisan, S, Hoarau, M. | | 登録日 | 2023-05-17 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Discovery of rigid biphenyl Plasmodium falciparum DHFR inhibitors using a fragment linking strategy.
Rsc Med Chem, 14, 2023
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8JFB
 | | V1/S quadruple mutant Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with compound 4 (B21588), NADPH and dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 3-[4-[[2,4-bis(azanyl)-6-ethyl-pyrimidin-5-yl]methyl]phenyl]benzoic acid, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | | 著者 | Vanichtanankul, J, Saeyang, T, Vitsupakorn, D, Saepua, S, Thongpanchang, C, Yuthavong, Y, Kamchonwongpaisan, S, Hoarau, M. | | 登録日 | 2023-05-17 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Discovery of rigid biphenyl Plasmodium falciparum DHFR inhibitors using a fragment linking strategy.
Rsc Med Chem, 14, 2023
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8JFD
 | | V1/S quadruple mutant Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with compound 8 (B21594), NADPH and dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 3-[3-[[2,4-bis(azanyl)-6-ethyl-pyrimidin-5-yl]methyl]phenyl]benzoic acid, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | | 著者 | Vanichtanankul, J, Saeyang, T, Vitsupakorn, D, Saepua, S, Thongpanchang, C, Yuthavong, Y, Kamchonwongpaisan, S, Hoarau, M. | | 登録日 | 2023-05-17 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Discovery of rigid biphenyl Plasmodium falciparum DHFR inhibitors using a fragment linking strategy.
Rsc Med Chem, 14, 2023
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6SOF
 | | human insulin receptor ectodomain bound by 4 insulin | | 分子名称: | Insulin, Insulin receptor | | 著者 | Gutmann, T, Schaefer, I.B, Poojari, C.S, Vattulainen, I, Strauss, M, Coskun, U. | | 登録日 | 2019-08-29 | | 公開日 | 2019-11-13 | | 最終更新日 | 2020-05-27 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Cryo-EM structure of the complete and ligand-saturated insulin receptor ectodomain.
J.Cell Biol., 219, 2020
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3SC1
 | | Novel Isoquinolone PDK1 Inhibitors Discovered through Fragment-Based Lead Discovery | | 分子名称: | 3-phosphoinositide-dependent protein kinase 1, 6-[2-(hydroxymethyl)phenyl]isoquinolin-1(2H)-one, GLYCEROL, ... | | 著者 | Greasley, S.E, Ferre, R.-A, Krauss, M, Cronin, C. | | 登録日 | 2011-06-06 | | 公開日 | 2011-10-26 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Novel isoquinolone PDK1 inhibitors discovered through fragment-based lead discovery.
J Comput Aided Mol Des, 25, 2011
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1RM8
 | | Crystal structure of the catalytic domain of MMP-16/MT3-MMP: Characterization of MT-MMP specific features | | 分子名称: | 4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE, CALCIUM ION, Matrix metalloproteinase-16, ... | | 著者 | Lang, R, Braun, M, Sounni, N.E, Noel, A, Frankenne, F, Foidart, J.-M, Bode, W, Maskos, K. | | 登録日 | 2003-11-27 | | 公開日 | 2004-03-09 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the catalytic domain of MMP-16/MT3-MMP: characterization of MT-MMP specific features.
J.Mol.Biol., 336, 2004
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1NL3
 | | CRYSTAL STRUCTURE OF THE SECA PROTEIN TRANSLOCATION ATPASE FROM MYCOBACTERIUM TUBERCULOSIS in APO FORM | | 分子名称: | PREPROTEIN TRANSLOCASE SECA 1 SUBUNIT | | 著者 | Sharma, V, Arockiasamy, A, Ronning, D.R, Savva, C.G, Holzenburg, A, Braunstein, M, Jacobs Jr, W.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2003-01-06 | | 公開日 | 2003-03-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of M. tuberculosis SecA, A Preprotein Translocating ATPase
Proc.Natl.Acad.Sci.USA, 100, 2003
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