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PDB: 94 件

4C6D
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Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 6.0
分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD PROTEIN, FORMIC ACID, ...
著者Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
登録日2013-09-18
公開日2014-02-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.298 Å)
主引用文献Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4C6F
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BU of 4c6f by Molmil
Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 6.5
分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, DIHYDROOROTASE, FORMIC ACID, ...
著者Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
登録日2013-09-18
公開日2014-02-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.261 Å)
主引用文献Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4BY3
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Crystal structure of the dihydroorotase domain of human CAD in apo- form obtained recombinantly from E. coli.
分子名称: DIHYDROOROTASE, FORMIC ACID, ZINC ION
著者Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
登録日2013-07-17
公開日2014-05-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structure, Functional Characterization, and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4C6L
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BU of 4c6l by Molmil
Crystal structure of the dihydroorotase domain of human CAD bound to the inhibitor fluoroorotate at pH 6.0
分子名称: 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD PROTEIN, FORMIC ACID, ...
著者Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
登録日2013-09-18
公開日2014-02-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4C6B
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BU of 4c6b by Molmil
Crystal structure of the dihydroorotase domain of human CAD with incomplete active site, obtained recombinantly from E. coli.
分子名称: CAD PROTEIN, FORMIC ACID, GLYCEROL
著者Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
登録日2013-09-18
公開日2014-02-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.656 Å)
主引用文献Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4C6P
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BU of 4c6p by Molmil
Crystal structure of the dihydroorotase domain of human CAD C1613S mutant in apo-form at pH 7.0
分子名称: CAD PROTEIN, FORMIC ACID, ZINC ION
著者Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
登録日2013-09-18
公開日2014-02-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.518 Å)
主引用文献Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4C6Q
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BU of 4c6q by Molmil
Crystal structure of the dihydroorotase domain of human CAD C1613S mutant bound to substrate at pH 7.0
分子名称: CAD PROTEIN, FORMIC ACID, N-CARBAMOYL-L-ASPARTATE, ...
著者Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
登録日2013-09-18
公開日2014-02-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.659 Å)
主引用文献Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
4C6J
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BU of 4c6j by Molmil
Crystal structure of the dihydroorotase domain of human CAD bound to substrate at pH 7.5
分子名称: (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, CAD PROTEIN, FORMIC ACID, ...
著者Ramon-Maiques, S, Lallous, N, Grande-Garcia, A.
登録日2013-09-18
公開日2014-02-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.299 Å)
主引用文献Structure, Functional Characterization and Evolution of the Dihydroorotase Domain of Human Cad.
Structure, 22, 2014
6RNS
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BU of 6rns by Molmil
Crystal structure of the dimerization domain of Gemin5 at 2.7 A
分子名称: Gem-associated protein 5, IODIDE ION
著者Moreno-Morcillo, M, Ramon-Maiques, S, Martinez-Salas, E.
登録日2019-05-09
公開日2019-11-27
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Structural basis for the dimerization of Gemin5 and its role in protein recruitment and translation control.
Nucleic Acids Res., 48, 2020
6RNQ
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Crystal structure of the dimerization domain of Gemin5 at 1.95 A
分子名称: Gem-associated protein 5, POTASSIUM ION
著者Moreno-Morcillo, M, Ramon-Maiques, S, Martinez-Salas, E.
登録日2019-05-09
公開日2019-11-27
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for the dimerization of Gemin5 and its role in protein recruitment and translation control.
Nucleic Acids Res., 48, 2020
3MR6
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BU of 3mr6 by Molmil
Human DNA polymerase eta - DNA ternary complex with a CPD 2bp upstream of the active site (TT4)
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*C*AP*TP*CP*AP*(TTD)P*AP*CP*GP*AP*GP*C)-3'), DNA (5'-D(*TP*CP*TP*CP*GP*TP*AP*AP*T)-3'), ...
著者Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W.
登録日2010-04-28
公開日2010-06-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure and mechanism of human DNA polymerase eta.
Nature, 465, 2010
3MR2
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BU of 3mr2 by Molmil
Human DNA polymerase eta in complex with normal DNA and incoming nucleotide (Nrm)
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*T*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
著者Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W.
登録日2010-04-28
公開日2010-06-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structure and mechanism of human DNA polymerase eta.
Nature, 465, 2010
3SI8
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BU of 3si8 by Molmil
Human DNA polymerase eta - DNA ternary complex with the 5'T of a CPD in the active site (TT2)
分子名称: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, ...
著者Biertumpfel, C, Zhao, Y, Kondo, Y, Ramon-Maiques, S, Gregory, M, Lee, J.Y, Masutani, C, Lehmann, A.R, Hanaoka, F, Yang, W.
登録日2011-06-17
公開日2011-08-03
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure and mechanism of human DNA polymerase eta.
Nature, 465, 2010
1X9Z
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BU of 1x9z by Molmil
Crystal structure of the MutL C-terminal domain
分子名称: CHLORIDE ION, DNA mismatch repair protein mutL, GLYCEROL, ...
著者Guarne, A, Ramon-Maiques, S, Wolff, E.M, Ghirlando, R, Hu, X, Miller, J.H, Yang, W.
登録日2004-08-24
公開日2004-10-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the MutL C-terminal domain: a model of intact MutL and its roles in mismatch repair
Embo J., 23, 2004
2MQK
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BU of 2mqk by Molmil
Solution structure of N terminal domain of the MuB AAA+ ATPase
分子名称: ATP-dependent target DNA activator B
著者Lopez-Mendez, B, Dramicanin, M, Campos-Olivas, R, Ramon-Maiques, S.
登録日2014-06-23
公開日2015-07-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of N terminal domain of the MuB AAA+ ATPase
To be Published
5G1N
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Aspartate transcarbamoylase domain of human CAD bound to PALA
分子名称: 1,2-ETHANEDIOL, CAD PROTEIN, N-(PHOSPHONACETYL)-L-ASPARTIC ACID
著者Ruiz-Ramos, A, Grande-Garcia, A, Moreno-Morcillo, M.D, Ramon-Maiques, S.
登録日2016-03-29
公開日2016-06-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala.
Structure, 24, 2016
5G1O
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BU of 5g1o by Molmil
Aspartate transcarbamoylase domain of human CAD in apo form
分子名称: 1,2-ETHANEDIOL, CAD protein, GLYCEROL
著者Ruiz-Ramos, A, Grande-Garcia, A, Moreno-Morcillo, M.D, Ramon-Maiques, S.
登録日2016-03-29
公開日2016-06-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala.
Structure, 24, 2016
3MR5
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BU of 3mr5 by Molmil
Human DNA polymerase eta - DNA ternary complex with a CPD 1bp upstream of the active site (TT3)
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*CP*GP*TP*CP*AP*TP*AP*A)-3'), DNA (5'-D(*TP*AP*AP*CP*(TTD)P*AP*TP*GP*AP*CP*GP*A)-3'), ...
著者Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W.
登録日2010-04-28
公開日2010-06-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and mechanism of human DNA polymerase eta.
Nature, 465, 2010
5G1P
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BU of 5g1p by Molmil
Aspartate transcarbamoylase domain of human CAD bound to carbamoyl phosphate
分子名称: CAD PROTEIN, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER
著者Ruiz-Ramos, A, Grande-Garcia, A, Moreno-Morcillo, M.D, Ramon-Maiques, S.
登録日2016-03-29
公開日2016-06-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Structure and Functional Characterization of Human Aspartate Transcarbamoylase, the Target of the Anti-Tumoral Drug Pala.
Structure, 24, 2016
3MR3
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BU of 3mr3 by Molmil
Human DNA polymerase eta - DNA ternary complex with the 3'T of a CPD in the active site (TT1)
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*CP*AP*(TTD)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*CP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
著者Biertumpfel, C, Zhao, Y, Ramon-Maiques, S, Gregory, M.T, Lee, J.Y, Yang, W.
登録日2010-04-28
公開日2010-06-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure and mechanism of human DNA polymerase eta.
Nature, 465, 2010
8BPS
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BU of 8bps by Molmil
Aspartate transcarbamoylase mutant (N2045C, R2238C) from Chaetomium thermophilum CAD-like in apo form
分子名称: Carbamoyl-phosphate synthase (glutamine-hydrolyzing), GLYCEROL
著者del Cano-Ochoa, F, Ramon-Maiques, S.
登録日2022-11-25
公開日2023-02-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献A Tailored Strategy to Crosslink the Aspartate Transcarbamoylase Domain of the Multienzymatic Protein CAD.
Molecules, 28, 2023
8BPL
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BU of 8bpl by Molmil
Aspartate transcarbamoylase mutant (N2045C, R2238C) from Chaetomium thermophilum CAD-like bound to carbamoyl phosphate
分子名称: Carbamoyl-phosphate synthase (glutamine-hydrolyzing), GLYCEROL, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER, ...
著者del Cano-Ochoa, F, Ramon-Maiques, S.
登録日2022-11-16
公開日2023-02-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献A Tailored Strategy to Crosslink the Aspartate Transcarbamoylase Domain of the Multienzymatic Protein CAD.
Molecules, 28, 2023
5NNQ
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BU of 5nnq by Molmil
Aspartate transcarbamoylase from Chaetomium thermophilum CAD-like bound to carbamoyl phosphate
分子名称: GLYCEROL, ctATC
著者Moreno-Morcillo, M, Grande-Garcia, A, Ramon-Maiques, S.
登録日2017-04-10
公開日2017-06-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis.
Structure, 25, 2017
5NNN
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Aspartate transcarbamoylase from Chaetomium thermophilum CAD-like
分子名称: GLYCEROL, ctATC
著者Moreno-Morcillo, M, Grande-Garcia, A, Ramon-Maiques, S.
登録日2017-04-10
公開日2017-06-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Structural Insight into the Core of CAD, the Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis.
Structure, 25, 2017
4BS1
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BU of 4bs1 by Molmil
MuB is an AAAplus ATPase that forms helical filaments to control target selection for DNA transposition
分子名称: ADENOSINE-5'-DIPHOSPHATE, TRANSCRIPTIONAL REGULATOR (NTRC FAMILY)
著者Mizuno, N, Dramicanin, M, Mizuuchi, M, Adam, J, Wang, Y, Han, Y.W, Yang, W, Steven, A.C, Mizuuchi, K, Ramon-Maiques, S.
登録日2013-06-06
公開日2013-07-03
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (18 Å)
主引用文献Mub is an Aaa+ ATPase that Forms Helical Filaments to Control Target Selection for DNA Transposition.
Proc.Natl.Acad.Sci.USA, 110, 2013

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