5BS0
 
 | | MAGE-A3 Reactive TCR in complex with Titin Epitope in HLA-A1 | | 分子名称: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | | 著者 | Raman, M.C.C, Rizkallah, P.J, Simmons, R, Donellan, Z, Dukes, J, Bossi, G, LeProvost, G, Mahon, T, Hickman, E, Lomax, M, Oates, J, Hassan, N, Vuidepot, A, Sami, M, Cole, D.K, Jakobsen, B.K. | | 登録日 | 2015-06-01 | | 公開日 | 2016-03-02 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy.
Sci Rep, 6, 2016
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5BRZ
 | | MAGE-A3 reactive TCR in complex with MAGE-A3 in HLA-A1 | | 分子名称: | Beta-2-microglobulin, GLU-VAL-ASP-PRO-ILE-GLY-HIS-LEU-TYR, HLA class I histocompatibility antigen, ... | | 著者 | Raman, M.C.C, Rizkallah, P.J, Simmons, R, Donnellan, Z, Dukes, J, Bossi, G, LeProvost, G, Mahon, T, Hickman, E, LomaX, M, Oates, J, Hassan, N, Vuidepot, A, Sami, M, Cole, D.K, Jakobsen, B.K. | | 登録日 | 2015-06-01 | | 公開日 | 2016-03-02 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy.
Sci Rep, 6, 2016
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2W8V
 | | SPT with PLP, N100W | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE | | 著者 | Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H. | | 登録日 | 2009-01-19 | | 公開日 | 2009-01-27 | | 最終更新日 | 2015-11-18 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
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2W8T
 | | SPT with PLP, N100C | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE | | 著者 | Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H. | | 登録日 | 2009-01-19 | | 公開日 | 2009-01-27 | | 最終更新日 | 2015-11-18 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
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2W8U
 | | SPT with PLP, N100Y | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE | | 著者 | Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H. | | 登録日 | 2009-01-19 | | 公開日 | 2009-01-27 | | 最終更新日 | 2015-11-18 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
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2W8W
 | | N100Y SPT with PLP-ser | | 分子名称: | SERINE PALMITOYLTRANSFERASE, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE | | 著者 | Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H. | | 登録日 | 2009-01-19 | | 公開日 | 2009-01-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
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2X8U
 | | Sphingomonas wittichii Serine palmitoyltransferase | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE | | 著者 | Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H. | | 登録日 | 2010-03-12 | | 公開日 | 2010-03-23 | | 最終更新日 | 2015-11-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Serine Palmitoyltransferase from Sphingomonas Wittichii Rw1 an Interesting Link to an Unusual Acyl Carrier Protein
Biopolymers, 93, 2010
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6L6Y
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2LZT
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3GYS
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3GQP
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3GQR
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3CY5
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3D4X
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3GDJ
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1U5Q
 | | Crystal Structure of the TAO2 Kinase Domain: Activation and Specifity of a Ste20p MAP3K | | 分子名称: | CALCIUM ION, serine/threonine protein kinase TAO2 | | 著者 | Zhou, T, Raman, M, Gao, Y, Earnest, S, Chen, Z, Machius, M, Cobb, M.H, Goldsmith, E.J. | | 登録日 | 2004-07-28 | | 公開日 | 2004-10-12 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of the TAO2 Kinase Domain; Activation and Specificity of a Ste20p MAP3K.
STRUCTURE, 12, 2004
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1U5R
 | | Crystal Structure of the TAO2 Kinase Domain: Activation and Specifity of a Ste20p MAP3K | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ... | | 著者 | Zhou, T, Raman, M, Gao, Y, Earnest, S, Chen, Z, Machius, M, Cobb, M.H, Goldsmith, E.J. | | 登録日 | 2004-07-28 | | 公開日 | 2004-10-12 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of the TAO2 Kinase Domain; Activation and Specificity of a Ste20p MAP3K.
Structure, 12, 2004
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2W8J
 | | SPT with PLP-ser | | 分子名称: | SERINE PALMITOYLTRANSFERASE, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE | | 著者 | Carter, L.G, Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H. | | 登録日 | 2009-01-16 | | 公開日 | 2009-01-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
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2XBN
 | | Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation | | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, MAGNESIUM ION, SERINE PALMITOYLTRANSFERASE | | 著者 | Lowther, J, Yard, B.A, Johnson, K.A, Carter, L.G, Bhat, V.T, Raman, M.C.C, Clarke, D.J, Ramakers, B, McMahon, S.A, Naismith, J.H, Campopiano, D.J. | | 登録日 | 2010-04-13 | | 公開日 | 2010-05-19 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Inhibition of the Plp-Dependent Enzyme Serine Palmitoyltransferase by Cycloserine: Evidence for a Novel Decarboxylative Mechanism of Inactivation.
Mol.Biosystems, 6, 2010
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1HPO
 | | HIV-1 PROTEASE TRIPLE MUTANT/U103265 COMPLEX | | 分子名称: | 4-CYANO-N-(3-CYCLOPROPYL(5,6,7,8,9,10-HEXAHYDRO-4-HYDROXY-2-OXO-CYCLOOCTA[B]PYRAN-3-YL)METHYL)PHENYL BENZENSULFONAMIDE, HIV-1 PROTEASE | | 著者 | Watenpaugh, K.D, Janakiraman, M.N. | | 登録日 | 1996-12-10 | | 公開日 | 1997-04-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure-based design of nonpeptidic HIV protease inhibitors: the sulfonamide-substituted cyclooctylpyramones.
J.Med.Chem., 40, 1997
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4UPJ
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7UPJ
 | | HIV-1 PROTEASE/U101935 COMPLEX | | 分子名称: | HIV-1 PROTEASE, N-(3-CYCLOPROPYL(5,6,7,8,9,10-HEXAHYDRO-2-OXO-2H-CYCLOOCTA[B]PYRAN-3-YL)METHYL)PHENYLBENZENSULFONAMIDE | | 著者 | Watenpaugh, K.D, Janakiraman, M.N. | | 登録日 | 1996-12-05 | | 公開日 | 1997-04-21 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure-based design of nonpeptidic HIV protease inhibitors: the sulfonamide-substituted cyclooctylpyramones.
J.Med.Chem., 40, 1997
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8COG
 | | Human arginylated beta-actin | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | 著者 | Pinto, C.S, Bakker, S.E, Suchenko, A, Hussain, H, Hatano, T, Sampath, K, Chinthalapudi, K, Mishima, M, Balasubramanian, M. | | 登録日 | 2023-02-28 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.499 Å) | | 主引用文献 | Structure and physiological investigation of human arginylated beta-actin
To Be Published
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1UPJ
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1INY
 | | A SIALIC ACID DERIVED PHOSPHONATE ANALOG INHIBITS DIFFERENT STRAINS OF INFLUENZA VIRUS NEURAMINIDASE WITH DIFFERENT EFFICIENCIES | | 分子名称: | (1R)-4-acetamido-1,5-anhydro-2,4-dideoxy-1-phosphono-D-glycero-D-galacto-octitol, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | White, C.L, Janakiraman, M.N, Laver, W.G, Philippon, C, Vasella, A, Air, G.M, Luo, M. | | 登録日 | 1994-09-26 | | 公開日 | 1995-02-07 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A sialic acid-derived phosphonate analog inhibits different strains of influenza virus neuraminidase with different efficiencies.
J.Mol.Biol., 245, 1995
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