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PDB: 263 件

2XSE
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The structural basis for recognition of J-base containing DNA by a novel DNA-binding domain in JBP1
分子名称: GLYCEROL, NITRATE ION, THYMINE DIOXYGENASE JBP1
著者Heidebrecht, T, Christodoulou, E, Chalmers, M.J, Jan, S, ter Riete, B, Grover, R.K, Joosten, R.P, Littler, D, vanLuenen, H, Griffin, P.R, Wentworth, P, Borst, P, Perrakis, A.
登録日2010-09-28
公開日2011-03-30
最終更新日2011-08-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Structural Basis for Recognition of Base J Containing DNA by a Novel DNA Binding Domain in Jbp1.
Nucleic Acids Res., 39, 2011
2XRG
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Crystal structure of Autotaxin (ENPP2) in complex with the HA155 boronic acid inhibitor
分子名称: CALCIUM ION, ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 2, IODIDE ION, ...
著者Hausmann, J, Albers, H.M.H.G, Perrakis, A.
登録日2010-09-14
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural Basis of Substrate Discrimination and Integrin Binding by Autotaxin.
Nat.Struct.Mol.Biol., 18, 2011
3TW2
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High resolution structure of human histidine triad nucleotide-binding protein 1 (hHINT1)/AMP complex in a monoclinic space group
分子名称: ADENOSINE MONOPHOSPHATE, Histidine triad nucleotide-binding protein 1
著者Dolot, R.M, Wlodarczyk, A, Ozga, M, Krakowiak, A, Nawrot, B.
登録日2011-09-21
公開日2011-11-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献A new crystal form of human histidine triad nucleotide-binding protein 1 (hHINT1) in complex with adenosine 5'-monophosphate at 1.38 A resolution.
Acta Crystallogr.,Sect.F, 68, 2012
4OAV
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Complete human RNase L in complex with 2-5A (5'-ppp heptamer), AMPPCP and RNA substrate.
分子名称: (2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-hydroxy-2-({[(S)-hydroxy{[(2R,3S,4S)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl]oxy}phosphoryl]oxy}methyl)tetrahydrofuran-3-yl dihydrogen phosphate, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Han, Y, Donovan, J, Rath, S, Whitney, G, Chitrakar, A, Korennykh, A.
登録日2014-01-06
公開日2014-03-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response.
Science, 343, 2014
2KLT
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Second Ca2+ binding domain of NCX1.3
分子名称: Sodium/calcium exchanger 1
著者Hilge, M, Aelen, J, Foarce, A, Perrakis, A, Vuister, G.W.
登録日2009-07-08
公開日2009-08-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism.
Proc.Natl.Acad.Sci.USA, 106, 2009
2KLS
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Apo-form of the second Ca2+ binding domain of NCX1.4
分子名称: Sodium/calcium exchanger 1
著者Hilge, M, Aelen, J, Foarce, A, Perrakis, A, Vuister, G.W.
登録日2009-07-08
公開日2009-08-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism.
Proc.Natl.Acad.Sci.USA, 106, 2009
3O1C
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High resolution crystal structure of histidine triad nucleotide-binding protein 1 (Hint1) C38A mutant from rabbit complexed with Adenosine
分子名称: ADENOSINE, Histidine triad nucleotide-binding protein 1, SODIUM ION
著者Dolot, R.M, Ozga, M, Krakowiak, A.K, Nawrot, B, Stec, W.J.
登録日2010-07-21
公開日2010-08-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Histidine Triad Nucleotide-binding Protein 1 (HINT-1) Phosphoramidase Transforms Nucleoside 5'-O-Phosphorothioates to Nucleoside 5'-O-Phosphates.
J.Biol.Chem., 285, 2010
1H7Z
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Adenovirus Ad3 fibre head
分子名称: ADENOVIRUS FIBRE PROTEIN, SULFATE ION
著者Durmort, C, Stehlin, C, Schoehn, G, Mitraki, A, Drouet, E, Cusack, S, Burmeister, W.P.
登録日2001-01-21
公開日2001-07-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of the Fiber Head of Ad3, a Non-Car-Binding Serotype of Adenovirus
Virology, 285, 2001
2V0R
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crystal structure of a hairpin exchange variant (LTx) of the targeting LINE-1 retrotransposon endonuclease
分子名称: LTX, SULFATE ION
著者Repanas, K, Zingler, N, Layer, L.E, Schumann, G.G, Perrakis, A, Weichenrieder, O.
登録日2007-05-17
公開日2007-07-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Determinants for DNA Target Structure Selectivity of the Human Line-1 Retrotransposon Endonuclease
Nucleic Acids Res., 35, 2007
3WSO
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Crystal structure of the Skp1-FBG3 complex
分子名称: F-box only protein 44, S-phase kinase-associated protein 1
著者Kumanomidou, T, Nishio, K, Takagi, K, Nakagawa, T, Suzuki, A, Yamane, T, Tokunaga, F, Iwai, K, Murakami, A, Yoshida, Y, Tanaka, K, Mizushima, T.
登録日2014-03-18
公開日2015-03-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Structural Differences between a Glycoprotein Specific F-Box Protein Fbs1 and Its Homologous Protein FBG3
Plos One, 10, 2015
4B94
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Crystal structure of human Mps1 TPR domain
分子名称: DI(HYDROXYETHYL)ETHER, DUAL SPECIFICITY PROTEIN KINASE TTK, GLYCEROL, ...
著者Littler, D, von Castelmur, E, De Marco, V, Perrakis, A.
登録日2012-08-31
公開日2013-04-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A Tpr Domain-Containing N-Terminal Module of Mps1 is Required for its Kinetochore Localization by Aurora B.
J.Cell Biol., 201, 2013
4B56
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Structure of ectonucleotide pyrophosphatase-phosphodiesterase-1 (NPP1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Jansen, S, Perrakis, A, Ulens, C, Winkler, C, Andries, M, Joosten, R.P, Van Acker, M, Luyten, F.P, Moolenaar, W.H, Bollen, M.
登録日2012-08-02
公開日2012-09-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of Npp1, an Ectonucleotide Pyrophosphatase/Phosphodiesterase Involved in Tissue Calcification.
Structure, 20, 2012
2Y7Y
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APLYSIA CALIFORNICA ACHBP IN APO STATE
分子名称: SOLUBLE ACETYLCHOLINE RECEPTOR
著者Ulens, C, Akdemir, A, Jongejan, A, van Elk, R, Bertrand, S, Perrakis, A, Leurs, R, Smit, A.B, Sixma, T.K, Bertrand, D, De Esch, I.J.
登録日2011-02-02
公開日2011-03-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.895 Å)
主引用文献Use of Acetylcholine Binding Protein in the Search for Novel Alpha7 Nicotinic Receptor Ligands. In Silico Docking, Pharmacological Screening, and X-Ray Analysis.
J.Med.Chem., 52, 2009
1QIU
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A triple beta-spiral in the adenovirus fibre shaft reveals a new structural motif for biological fibres
分子名称: ADENOVIRUS FIBRE
著者van Raaij, M.J, Lavigne, G, Mitraki, A, Cusack, S.
登録日1999-06-16
公開日1999-10-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A triple beta-spiral in the adenovirus fibre shaft reveals a new structural motif for a fibrous protein.
Nature, 401, 1999
1RXF
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DEACETOXYCEPHALOSPORIN C SYNTHASE COMPLEXED WITH FE(II)
分子名称: DEACETOXYCEPHALOSPORIN C SYNTHASE, FE (III) ION
著者Valegard, K, Terwisscha Van Scheltinga, A.C, Lloyd, M.D, Hara, T, Ramaswamy, S, Perrakis, A, Thompson, A, Lee, H.J, Baldwin, J.E, Schofield, C.J, Hajdu, J, Andersson, I.
登録日1998-06-05
公開日1999-06-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of a cephalosporin synthase.
Nature, 394, 1998
3O1X
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High resolution crystal structure of histidine triad nucleotide-binding protein 1 (Hint1) C84A mutant from rabbit complexed with adenosine
分子名称: ADENOSINE, Histidine triad nucleotide-binding protein 1, SODIUM ION
著者Dolot, R.M, Ozga, M, Krakowiak, A.K, Nawrot, B, Stec, W.J.
登録日2010-07-22
公開日2010-08-04
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Histidine Triad Nucleotide-binding Protein 1 (HINT-1) Phosphoramidase Transforms Nucleoside 5'-O-Phosphorothioates to Nucleoside 5'-O-Phosphates.
J.Biol.Chem., 285, 2010
1VYB
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Endonuclease domain of human LINE1 ORF2p
分子名称: GLYCEROL, ORF2 CONTAINS A REVERSE TRANSCRIPTASE DOMAIN, SULFATE ION, ...
著者Weichenrieder, O, Repanas, K, Perrakis, A.
登録日2004-04-25
公開日2004-06-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the targeting endonuclease of the human LINE-1 retrotransposon.
Structure, 12, 2004
1RCQ
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The 1.45 A crystal structure of alanine racemase from a pathogenic bacterium, Pseudomonas aeruginosa, contains both internal and external aldimine forms
分子名称: D-LYSINE, PYRIDOXAL-5'-PHOSPHATE, catabolic alanine racemase DadX
著者Le Magueres, P, Im, H, Dvorak, A, Strych, U, Benedik, M, Krause, K.L.
登録日2003-11-04
公開日2004-06-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure at 1.45 A resolution of alanine racemase from a pathogenic bacterium, Pseudomonas aeruginosa, contains both internal and external aldimine forms.
Biochemistry, 42, 2003
2V0S
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crystal structure of a hairpin exchange variant (LR1) of the targeting LINE-1 retrotransposon endonuclease
分子名称: GLYCEROL, LR1, MANGANESE (II) ION, ...
著者Repanas, K, Zingler, N, Layer, L.E, Schumann, G.G, Perrakis, A, Weichenrieder, O.
登録日2007-05-17
公開日2007-07-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Determinants for DNA Target Structure Selectivity of the Human Line-1 Retrotransposon Endonuclease.
Nucleic Acids Res., 35, 2007
2YLM
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Mechanism of USP7 (HAUSP) activation by its C-terminal ubiquitin-like domain (HUBL) and allosteric regulation by GMP-synthetase.
分子名称: CHLORIDE ION, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7
著者Faesen, A.C, Perrakis, A, Sixma, T.K.
登録日2011-06-03
公開日2011-10-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Mechanism of Usp7/Hausp Activation by its C- Terminal Ubiquitin-Like Domain and Allosteric Regulation by Gmp-Synthetase
Mol.Cell, 44, 2011
1V6J
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peanut lectin-lactose complex crystallized in orthorhombic form at acidic pH
分子名称: CALCIUM ION, Galactose-binding lectin, MANGANESE (II) ION, ...
著者Kundhavai Natchiar, S, Arockia Jeyaprakash, A, Ramya, T.N.C, Thomas, C.J, Suguna, K, Surolia, A, Vijayan, M.
登録日2003-12-01
公開日2004-02-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural plasticity of peanut lectin: an X-ray analysis involving variation in pH, ligand binding and crystal structure.
Acta Crystallogr.,Sect.D, 60, 2004
1V6L
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Peanut lectin-lactose complex in the presence of 9mer peptide (PVIWSSATG)
分子名称: CALCIUM ION, Galactose-binding lectin, MANGANESE (II) ION, ...
著者Kundhavai Natchiar, S, Arockia Jeyaprakash, A, Ramya, T.N.C, Thomas, C.J, Suguna, K, Surolia, A, Vijayan, M.
登録日2003-12-01
公開日2004-02-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural plasticity of peanut lectin: an X-ray analysis involving variation in pH, ligand binding and crystal structure.
Acta Crystallogr.,Sect.D, 60, 2004
1V6K
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Peanut lectin-lactose complex in the presence of peptide(IWSSAGNVA)
分子名称: CALCIUM ION, Galactose-binding lectin, MANGANESE (II) ION, ...
著者Kundhavai Natchiar, S, Arockia Jeyaprakash, A, Ramya, T.N.C, Thomas, C.J, Suguna, K, Surolia, A, Vijayan, M.
登録日2003-12-01
公開日2004-02-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural plasticity of peanut lectin: an X-ray analysis involving variation in pH, ligand binding and crystal structure.
Acta Crystallogr.,Sect.D, 60, 2004
1V6I
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Peanut lectin-lactose complex in acidic pH
分子名称: CALCIUM ION, Galactose-binding lectin, MANGANESE (II) ION, ...
著者Kundhavai Natchiar, S, Arockia Jeyaprakash, A, Ramya, T.N.C, Thomas, C.J, Suguna, K, Surolia, A, Vijayan, M.
登録日2003-12-01
公開日2004-02-10
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural plasticity of peanut lectin: an X-ray analysis involving variation in pH, ligand binding and crystal structure.
Acta Crystallogr.,Sect.D, 60, 2004
1V1I
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Adenovirus fibre shaft sequence N-terminally fused to the bacteriophage T4 fibritin foldon trimerisation motif with a long linker
分子名称: FIBRITIN, FIBER PROTEIN
著者Papanikolopoulou, K, Teixeira, S, Belrhali, H, Forsyth, V.T, Mitraki, A, van Raaij, M.J.
登録日2004-04-16
公開日2004-07-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Adenovirus Fibre Shaft Sequences Fold Into the Native Triple Beta-Spiral Fold When N-Terminally Fused to the Bacteriophage T4 Fibritin Foldon Trimerisation Motif
J.Mol.Biol., 342, 2004

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