5LOH
| Kinase domain of human Greatwall | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, STAUROSPORINE, ... | 著者 | Rajasekaran, M.B, Pearl, L.H, Oliver, A.W. | 登録日 | 2016-08-09 | 公開日 | 2016-09-07 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | A first generation inhibitor of human Greatwall kinase, enabled by structural and functional characterisation of a minimal kinase domain construct. Oncotarget, 7, 2016
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4UW1
| X-ray crystal structure of human TNKS in complex with a small molecule inhibitor | 分子名称: | 1,2-ETHANEDIOL, 3-{4-[(dimethylamino)methyl]phenyl}-5-methoxyisoquinolin-1(2H)-one, GLYCEROL, ... | 著者 | Oliver, A.W, Rajasekaran, M.B, Pearl, L.H. | 登録日 | 2014-08-08 | 公開日 | 2015-07-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.37 Å) | 主引用文献 | Design and Discovery of 3-Aryl-5-Substituted-Isoquinolin-1-Ones as Potent and Selective Tankyrase Inhibitors Medchemcommm, 6, 2015
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7Q1G
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4UUH
| X-ray crystal structure of human TNKS in complex with a small molecule inhibitor | 分子名称: | 1,2-ETHANEDIOL, 5-methyl-3-[4-(piperazin-1-ylmethyl)phenyl]isoquinolin-1(2H)-one, GLYCEROL, ... | 著者 | Oliver, A.W, Rajasekaran, M.B, Pearl, L.H. | 登録日 | 2014-07-28 | 公開日 | 2015-07-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Design and Discovery of 3-Aryl-5-Substituted-Isoquinolin-1- Ones as Potent and Selective Tankyrase Inhibitors Medchemcommm, 6, 2015
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2KDZ
| Structure of the R2R3 DNA binding domain of MYB1 protein from protozoan parasite trichomonas vaginalis in complex with MRE-1/MRE-2R DNA | 分子名称: | 5'-D(*AP*AP*GP*AP*TP*AP*AP*CP*GP*AP*TP*AP*TP*TP*TP*A)-3', 5'-D(*TP*AP*AP*AP*TP*AP*TP*CP*GP*TP*TP*AP*TP*CP*TP*T)-3', MYB24 | 著者 | Lou, Y.C, Wei, S.Y, Rajasekaran, M, Chou, C.C, Hsu, H.M, Tai, J.H, Chen, C. | 登録日 | 2009-01-21 | 公開日 | 2009-03-17 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structural analysis of DNA recognition by a novel Myb1 DNA-binding domain in the protozoan parasite Trichomonas vaginalis. Nucleic Acids Res., 2009
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2K9N
| Solution NMR structure of the R2R3 DNA binding domain of Myb1 protein from protozoan parasite Trichomonas vaginalis | 分子名称: | MYB24 | 著者 | Lou, Y, Wei, S, Rajasekaran, M, Chou, C, Hsu, H, Tai, J, Chen, C. | 登録日 | 2008-10-19 | 公開日 | 2009-03-17 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structural analysis of DNA recognition by a novel Myb1 DNA-binding domain in the protozoan parasite Trichomonas vaginalis. Nucleic Acids Res., 37, 2009
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