5XX9
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1DAJ
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![BU of 1daj by Molmil](/molmil-images/mine/1daj) | COMPARISON OF TERNARY COMPLEXES OF PNEUMOCYSTIS CARINII AND WILD TYPE HUMAN DIHYDROFOLATE REDUCTASE WITH COENZYME NADPH AND A NOVEL CLASSICAL ANTITUMOR FURO[2,3D]PYRIMIDINE ANTIFOLATE | Descriptor: | DIHYDROFOLATE REDUCTASE, N-[4-[(2,4-DIAMINOFURO[2,3D]PYRIMIDIN-5-YL)METHYL]METHYLAMINO]-BENZOYL]-L-GLUTAMATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Gangjee, A, Devraj, R, Queener, S.F, Blakley, R.L. | Deposit date: | 1997-07-29 | Release date: | 1997-12-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Comparison of ternary complexes of Pneumocystis carinii and wild-type human dihydrofolate reductase with coenzyme NADPH and a novel classical antitumor furo[2,3-d]pyrimidine antifolate. Acta Crystallogr.,Sect.D, 53, 1997
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1SGU
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![BU of 1sgu by Molmil](/molmil-images/mine/1sgu) | Comparing the Accumulation of Active Site and Non-active Site Mutations in the HIV-1 Protease | Descriptor: | N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE, POL polyprotein | Authors: | Clemente, J.C, Moose, R.E, Hemrajani, R, Govindasamy, L, Reutzel, R, Mckenna, R, Abandje-McKenna, M, Goodenow, M.M, Dunn, B.M. | Deposit date: | 2004-02-24 | Release date: | 2004-10-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Comparing the Accumulation of Active- and Nonactive-Site Mutations in the HIV-1 Protease. Biochemistry, 43, 2004
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1SH9
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![BU of 1sh9 by Molmil](/molmil-images/mine/1sh9) | Comparing the Accumulation of Active Site and Non-active Site Mutations in the HIV-1 Protease | Descriptor: | POL polyprotein, RITONAVIR | Authors: | Clemente, J.C, Moose, R.E, Hemrajani, R, Govindasamy, L, Reutzel, R, McKenna, R, Abanje-McKenna, M, Goodenow, M.M, Dunn, B.M. | Deposit date: | 2004-02-25 | Release date: | 2004-10-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Comparing the Accumulation of Active- and Nonactive-Site Mutations in the HIV-1 Protease. Biochemistry, 43, 2004
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5KR8
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![BU of 5kr8 by Molmil](/molmil-images/mine/5kr8) | (4~{S},6~{S})-4-[2,4-bis(fluoranyl)phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine (compound 5) bound to BACE1 | Descriptor: | (4~{S},6~{S})-4-[2,4-bis(fluoranyl)phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine, Beta-secretase 1, IODIDE ION | Authors: | Lewis, H.A, Wu, Y.J, Rajamani, R, Thompson, L.A. | Deposit date: | 2016-07-07 | Release date: | 2016-09-07 | Last modified: | 2016-10-05 | Method: | X-RAY DIFFRACTION (2.118 Å) | Cite: | Discovery of S3-Truncated, C-6 Heteroaryl Substituted Aminothiazine beta-Site APP Cleaving Enzyme-1 (BACE1) Inhibitors. J.Med.Chem., 59, 2016
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1NKG
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![BU of 1nkg by Molmil](/molmil-images/mine/1nkg) | Rhamnogalacturonan lyase from Aspergillus aculeatus | Descriptor: | CALCIUM ION, Rhamnogalacturonase B, SULFATE ION | Authors: | McDonough, M.A, Kadirvelraj, R, Harris, P, Poulsen, J.C, Larsen, S. | Deposit date: | 2003-01-03 | Release date: | 2004-05-25 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Rhamnogalacturonan lyase reveals a unique three-domain modular structure for polysaccharide lyase family 4. Febs Lett., 565, 2004
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1D5H
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![BU of 1d5h by Molmil](/molmil-images/mine/1d5h) | Rnase s(f8a). mutant ribonucleasE S. | Descriptor: | RNASE S, S PEPTIDE, SULFATE ION | Authors: | Ratnaparkhi, G.S, Varadarajan, R. | Deposit date: | 1999-10-07 | Release date: | 1999-10-20 | Last modified: | 2018-03-14 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Thermodynamic and structural studies of cavity formation in proteins suggest that loss of packing interactions rather than the hydrophobic effect dominates the observed energetics. Biochemistry, 39, 2000
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4ZNP
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![BU of 4znp by Molmil](/molmil-images/mine/4znp) | The structure of A pfI Riboswitch Bound to ZMP | Descriptor: | AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, MAGNESIUM ION, pfI Riboswitch | Authors: | Ren, A, Patel, D.J, Rajashankar, R.K. | Deposit date: | 2015-05-05 | Release date: | 2015-08-26 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Global RNA Fold and Molecular Recognition for a pfl Riboswitch Bound to ZMP, a Master Regulator of One-Carbon Metabolism. Structure, 23, 2015
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1D5D
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5VCR
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![BU of 5vcr by Molmil](/molmil-images/mine/5vcr) | Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase with bound uranium dioxide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, CHLORIDE ION, ... | Authors: | Sanders, J.H, Kadirvelraj, R, Wood, Z.A. | Deposit date: | 2017-03-31 | Release date: | 2018-04-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.992 Å) | Cite: | HumanN-acetylglucosaminyltransferase II substrate recognition uses a modular architecture that includes a convergent exosite. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1FEV
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2RLN
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1D5E
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5VCS
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![BU of 5vcs by Molmil](/molmil-images/mine/5vcs) | Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase with Bound Acceptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, ... | Authors: | Sanders, J.H, Kadirvelraj, R, Wood, Z.A. | Deposit date: | 2017-03-31 | Release date: | 2018-04-11 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.799 Å) | Cite: | HumanN-acetylglucosaminyltransferase II substrate recognition uses a modular architecture that includes a convergent exosite. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1CJQ
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1J80
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![BU of 1j80 by Molmil](/molmil-images/mine/1j80) | Osmolyte Stabilization of RNase | Descriptor: | RIBONUCLEASE PANCREATIC, SULFATE ION | Authors: | Ratnaparkhi, G.S, Varadarajan, R. | Deposit date: | 2001-05-19 | Release date: | 2001-06-06 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states. J.Biol.Chem., 276, 2001
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1CJR
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1J82
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![BU of 1j82 by Molmil](/molmil-images/mine/1j82) | Osmolyte Stabilization of RNase | Descriptor: | RIBONUCLEASE PANCREATIC, SULFATE ION | Authors: | Ratnaparkhi, G.S, Varadarajan, R. | Deposit date: | 2001-05-19 | Release date: | 2001-06-06 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states. J.Biol.Chem., 276, 2001
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1J7Z
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![BU of 1j7z by Molmil](/molmil-images/mine/1j7z) | Osmolyte Stabilization of Ribonuclease | Descriptor: | RIBONUCLEASE PANCREATIC, SULFATE ION | Authors: | Ratnaparkhi, G.S, Varadarajan, R. | Deposit date: | 2001-05-19 | Release date: | 2001-06-06 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states. J.Biol.Chem., 276, 2001
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1J81
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![BU of 1j81 by Molmil](/molmil-images/mine/1j81) | Osmolyte Stabilization of RNase | Descriptor: | RIBONUCLEASE PANCREATIC, SULFATE ION | Authors: | Ratnaparkhi, G.S, Varadarajan, R. | Deposit date: | 2001-05-19 | Release date: | 2001-06-06 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states. J.Biol.Chem., 276, 2001
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3CWG
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![BU of 3cwg by Molmil](/molmil-images/mine/3cwg) | Unphosphorylated mouse STAT3 core fragment | Descriptor: | Signal transducer and activator of transcription 3 | Authors: | Ren, Z, Mao, X, Mertens, C, Krishnaraj, R, Qin, J, Mandal, P.K, Romanowshi, M.J, McMurray, J.S. | Deposit date: | 2008-04-21 | Release date: | 2008-07-01 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Crystal structure of unphosphorylated STAT3 core fragment. Biochem.Biophys.Res.Commun., 374, 2008
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1RNU
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![BU of 1rnu by Molmil](/molmil-images/mine/1rnu) | REFINEMENT OF THE CRYSTAL STRUCTURE OF RIBONUCLEASE S. COMPARISON WITH AND BETWEEN THE VARIOUS RIBONUCLEASE A STRUCTURES | Descriptor: | RIBONUCLEASE S, SULFATE ION | Authors: | Kim, E.E, Varadarajan, R, Wyckoff, H.W, Richards, F.M. | Deposit date: | 1992-02-19 | Release date: | 1994-01-31 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Refinement of the crystal structure of ribonuclease S. Comparison with and between the various ribonuclease A structures. Biochemistry, 31, 1992
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1RNV
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![BU of 1rnv by Molmil](/molmil-images/mine/1rnv) | REFINEMENT OF THE CRYSTAL STRUCTURE OF RIBONUCLEASE S. COMPARISON WITH AND BETWEEN THE VARIOUS RIBONUCLEASE A STRUCTURES | Descriptor: | RIBONUCLEASE S, SULFATE ION | Authors: | Kim, E.E, Varadarajan, R, Wyckoff, H.W, Richards, F.M. | Deposit date: | 1992-02-19 | Release date: | 1994-01-31 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Refinement of the crystal structure of ribonuclease S. Comparison with and between the various ribonuclease A structures. Biochemistry, 31, 1992
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4L1D
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![BU of 4l1d by Molmil](/molmil-images/mine/4l1d) | Voltage-gated sodium channel beta3 subunit Ig domain | Descriptor: | Sodium channel subunit beta-3 | Authors: | Namadurai, S, Weimhofer, M, Rajappa, R, Stott, K, Klingauf, J, Chirgadze, D.Y, Jackson, A.P. | Deposit date: | 2013-06-03 | Release date: | 2014-03-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure and Molecular Imaging of the Nav Channel beta 3 Subunit Indicates a Trimeric Assembly. J.Biol.Chem., 289, 2014
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2RNS
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![BU of 2rns by Molmil](/molmil-images/mine/2rns) | REFINEMENT OF THE CRYSTAL STRUCTURE OF RIBONUCLEASE S. COMPARISON WITH AND BETWEEN THE VARIOUS RIBONUCLEASE A STRUCTURES | Descriptor: | RIBONUCLEASE S, SULFATE ION | Authors: | Kim, E.E, Varadarajan, R, Wyckoff, H.W, Richards, F.M. | Deposit date: | 1992-02-19 | Release date: | 1994-01-31 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Refinement of the crystal structure of ribonuclease S. Comparison with and between the various ribonuclease A structures. Biochemistry, 31, 1992
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