5VCS

Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase with Bound Acceptor

Summary for 5VCS

Entry DOI	10.2210/pdb5vcs/pdb
Related	5VCM 5VCR
Descriptor	Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	glycosyltransferase, mgat2, complex n-gly, branched acceptor, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	99300.81
Authors	Sanders, J.H.,Kadirvelraj, R.,Wood, Z.A. (deposition date: 2017-03-31, release date: 2018-04-11, Last modification date: 2023-10-04)
Primary citation	Kadirvelraj, R.,Yang, J.Y.,Sanders, J.H.,Liu, L.,Ramiah, A.,Prabhakar, P.K.,Boons, G.J.,Wood, Z.A.,Moremen, K.W. HumanN-acetylglucosaminyltransferase II substrate recognition uses a modular architecture that includes a convergent exosite. Proc. Natl. Acad. Sci. U.S.A., 115:4637-4642, 2018 Cited by PubMed: 29666272 DOI: 10.1073/pnas.1716988115 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.799 Å)

Structure validation