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PDB: 924 件

1X6X
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Structure 2: cryocolled crystal structure of the truncated pak pilin from Pseudomonas aeruginosa at 0.95A resolution
分子名称: Fimbrial protein
著者Dunlop, K.V, Irvin, R.T, Hazes, B.
登録日2004-08-12
公開日2005-04-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (0.96 Å)
主引用文献Pros and cons of cryocrystallography: should we also collect a room-temperature data set?
Acta Crystallogr.,Sect.D, 61, 2005
1X6Y
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Structure 6: room temperature crystal structure of the truncated pak pilin from Pseudomonas aeruginosa at 1.80A resolution
分子名称: Fimbrial protein
著者Dunlop, K.V, Irvin, R.T, Hazes, B.
登録日2004-08-12
公開日2005-04-26
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Pros and cons of cryocrystallography: should we also collect a room-temperature data set?
Acta Crystallogr.,Sect.D, 61, 2005
1VWF
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STREPTAVIDIN COMPLEXED WITH CYCLO-AC-[CHPQGPPC]-NH2 MONOMER, PH 3.67
分子名称: PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN
著者Katz, B.A, Cass, R.T.
登録日1997-03-03
公開日1998-03-18
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0.
J.Biol.Chem., 272, 1997
1VWB
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STREPTAVIDIN-CYCLO-AC-[CHPQFC]-NH2, PH 11.8
分子名称: PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN
著者Katz, B.A, Cass, R.T.
登録日1997-03-03
公開日1998-03-18
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0.
J.Biol.Chem., 272, 1997
1JQF
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Human Transferrin N-Lobe Mutant H249Q
分子名称: CARBONATE ION, FE (III) ION, POTASSIUM ION, ...
著者Baker, H.M, Mason, A.B, He, Q.-Y, MacGillivray, R.T.A, Baker, E.N.
登録日2001-08-06
公開日2001-10-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Ligand variation in the transferrin family: the crystal structure of the H249Q mutant of the human transferrin N-lobe as a model for iron binding in insect transferrins.
Biochemistry, 40, 2001
3NPQ
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Structure of the S-adenosylhomocysteine riboswitch at 2.18 A
分子名称: COBALT HEXAMMINE(III), S-ADENOSYL-L-HOMOCYSTEINE, S-ADENOSYLHOMOCYSTEINE RIBOSWITCH
著者Reyes, F.E, Edwards, A.E, Batey, R.T.
登録日2010-06-28
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1814 Å)
主引用文献Structural basis for recognition of S-adenosylhomocysteine by riboswitches.
Rna, 16, 2010
3O2H
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E. coli ClpS in complex with a Leu N-end rule peptide
分子名称: ATP-dependent Clp protease adaptor protein ClpS, DNA protection during starvation protein
著者Roman-Hernandez, G, Grant, R.A, Sauer, R.T, Baker, T.A, de Regt, A.
登録日2010-07-22
公開日2011-12-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The ClpS adaptor mediates staged delivery of N-end rule substrates to the AAA+ ClpAP protease.
Mol.Cell, 43, 2011
3O2O
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Structure of E. coli ClpS ring complex
分子名称: ATP-dependent Clp protease adaptor protein ClpS
著者Roman-Hernandez, G, Grant, R.A, Sauer, R.T, Baker, T.A, de Regt, A.
登録日2010-07-22
公開日2011-12-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The ClpS adaptor mediates staged delivery of N-end rule substrates to the AAA+ ClpAP protease.
Mol.Cell, 43, 2011
3NPN
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Structure of the s-adenosylhomocysteine riboswitch at 3.0A
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, S-ADENOSYLHOMOCYSTEINE RIBOSWITCH
著者Reyes, F.E, Edwards, A.E, Batey, R.T.
登録日2010-06-28
公開日2010-10-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.792 Å)
主引用文献Structural basis for recognition of S-adenosylhomocysteine by riboswitches.
Rna, 16, 2010
3QZ0
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Structure of Treponema denticola Factor H Binding protein (FhbB), selenomethionine derivative
分子名称: Factor H binding protein, GLYCEROL, THIOCYANATE ION
著者Miller, D.P, McDowell, J.V, Heroux, A, Bell, J.K, Marconi, R.T, Conrad, D.H, Burgner, J.W.
登録日2011-03-04
公開日2012-03-07
最終更新日2012-06-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Structure of factor H-binding protein B (FhbB) of the periopathogen, Treponema denticola: insights into progression of periodontal disease.
J.Biol.Chem., 287, 2012
3RSD
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STRUCTURE OF THE D121N VARIANT OF RIBONUCLEASE A
分子名称: RIBONUCLEASE A
著者Schultz, L.W, Quirk, D.J, Raines, R.T.
登録日1998-02-05
公開日1998-07-15
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献His...Asp catalytic dyad of ribonuclease A: structure and function of the wild-type, D121N, and D121A enzymes.
Biochemistry, 37, 1998
3R15
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Structure Treponema Denticola Factor H Binding Protein
分子名称: Factor H binding protein, THIOCYANATE ION
著者Miller, D.P, McDowell, J.V, Burgner, J, Heroux, A, Bell, J.K, Marconi, R.T.
登録日2011-03-09
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Structure Treponema Denticola Factor H Binding Protein
To be Published
3QTL
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Structural Basis for Dual-inhibition Mechanism of a Non-classical Kazal-type Serine Protease Inhibitor from Horseshoe Crab in Complex with Subtilisin
分子名称: Kazal-type serine protease inhibitor SPI-1, Subtilisin-like serin protease
著者Shenoy, R.T, Sivaraman, J.
登録日2011-02-23
公開日2011-06-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for dual-inhibition mechanism of a non-classical kazal-type serine protease inhibitor from horseshoe crab in complex with subtilisin.
Plos One, 6, 2011
3OTP
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Crystal structure of the DegP dodecamer with a model substrate
分子名称: Lysozyme C, Protease do
著者Kim, S, Grant, R.A, Sauer, R.T.
登録日2010-09-13
公開日2011-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.76 Å)
主引用文献Covalent Linkage of Distinct Substrate Degrons Controls Assembly and Disassembly of DegP Proteolytic Cages.
Cell(Cambridge,Mass.), 145, 2011
3RSK
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STRUCTURE OF THE K7A/R10A/K66A VARIANT OF RIBONUCLEASE A
分子名称: ACETATE ION, RIBONUCLEASE A
著者Schultz, L.W, Fisher, B.M, Raines, R.T.
登録日1998-04-09
公開日1998-07-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Coulombic Effects of Remote Subsites on the Active Site of Ribonuclease A
Biochemistry, 37, 1998
3RSP
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STRUCTURE OF THE P93G VARIANT OF RIBONUCLEASE A
分子名称: CHLORIDE ION, RIBONUCLEASE A
著者Schultz, L.W, Hargraves, S.R, Klink, T.A, Raines, R.T.
登録日1997-10-20
公開日1998-04-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and stability of the P93G variant of ribonuclease A.
Protein Sci., 7, 1998
3OU0
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re-refined 3CS0
分子名称: Periplasmic serine endoprotease DegP, heptapeptide, pentapeptide
著者Sauer, R.T, Grant, R.A, Kim, S.
登録日2010-09-14
公開日2011-01-19
最終更新日2012-02-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Covalent Linkage of Distinct Substrate Degrons Controls Assembly and Disassembly of DegP Proteolytic Cages.
Cell(Cambridge,Mass.), 145, 2011
3OF8
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Structural Basis for Reversible and Irreversible Inhibition of Human Cathepsin L by their Respective Dipeptidyl Glyoxal and Diazomethylketone Inhibitors
分子名称: Cathepsin L1, Nalpha-[(benzyloxy)carbonyl]-N-[(2S)-1-(4-tert-butoxyphenyl)-4-hydroxy-3-oxobutan-2-yl]-L-phenylalaninamide
著者Shenoy, R.T, Sivaraman, J.
登録日2010-08-14
公開日2010-12-08
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for reversible and irreversible inhibition of human cathepsin L by their respective dipeptidyl glyoxal and diazomethylketone inhibitors.
J.Struct.Biol., 173, 2011
3OF9
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Structural Basis for Irreversible Inhibition of Human Cathepsin L by a Diazomethylketone Inhibitor
分子名称: Cathepsin L1, Nalpha-[(benzyloxy)carbonyl]-N-[(1S)-1-(4-tert-butoxybenzyl)-3-diazo-2-oxopropyl]-L-phenylalaninamide
著者Shenoy, R.T, Sivaraman, J.
登録日2010-08-14
公開日2010-12-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.761 Å)
主引用文献Structural basis for reversible and irreversible inhibition of human cathepsin L by their respective dipeptidyl glyoxal and diazomethylketone inhibitors.
J.Struct.Biol., 173, 2011
3SD3
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The structure of the tetrahydrofolate riboswitch containing a U25C mutation
分子名称: IRIDIUM HEXAMMINE ION, N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, Tetrahydrofolate riboswitch
著者Reyes, F.E, Trausch, J.J, Ceres, P, Batey, R.T.
登録日2011-06-08
公開日2011-09-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The structure of a tetrahydrofolate-sensing riboswitch reveals two ligand binding sites in a single aptamer.
Structure, 19, 2011
1SDL
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CROSS-LINKED, CARBONMONOXY HEMOGLOBIN A
分子名称: 1,3,5-BENZENETRICARBOXYLIC ACID, CARBON MONOXIDE, HEMOGLOBIN A, ...
著者Schumacher, M.A, Dixon, M.M, Kluger, R, Jones, R.T, Brennan, R.G.
登録日1996-02-26
公開日1996-08-01
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Allosteric transition intermediates modelled by crosslinked haemoglobins.
Nature, 375, 1995
3DDW
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Crystal structure of glycogen phosphorylase complexed with an anthranilimide based inhibitor GSK055
分子名称: (2S)-{[(3-{[(2-chloro-6-methylphenyl)carbamoyl]amino}naphthalen-2-yl)carbonyl]amino}(phenyl)ethanoic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者Nolte, R.T.
登録日2008-06-06
公開日2009-01-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy.
Bioorg.Med.Chem.Lett., 19, 2009
3DDS
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Crystal structure of glycogen phosphorylase complexed with an anthranilimide based inhibitor GSK261
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CAFFEINE, ...
著者Nolte, R.T.
登録日2008-06-06
公開日2009-01-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy.
Bioorg.Med.Chem.Lett., 19, 2009
3CJF
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Crystal structure of VEGFR2 in complex with a 3,4,5-trimethoxy aniline containing pyrimidine
分子名称: N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine, SULFATE ION, Vascular endothelial growth factor receptor 2
著者Nolte, R.T.
登録日2008-03-12
公開日2008-10-07
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor.
J.Med.Chem., 51, 2008
1TXX
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ACTIVE-SITE VARIANT OF E.COLI THIOREDOXIN
分子名称: COPPER (II) ION, PROTEIN (THIOREDOXIN)
著者Schultz, L.W, Chivers, P.T, Raines, R.T.
登録日1999-04-07
公開日1999-09-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The CXXC motif: crystal structure of an active-site variant of Escherichia coli thioredoxin.
Acta Crystallogr.,Sect.D, 55, 1999

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