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PDB: 2930 件

3LBS
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Crystal structure of the cytoplasmic tail of (pro)renin receptor as a MBP fusion (Maltose-bound form)
分子名称: Maltose-binding periplasmic protein, Renin receptor, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Zhang, Y, Garavito, R.M.
登録日2010-01-08
公開日2011-02-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural analysis of the intracellular domain of (pro)renin receptor fused to maltose-binding protein.
Biochem.Biophys.Res.Commun., 407, 2011
4V5G
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The crystal structure of the 70S ribosome bound to EF-Tu and tRNA
分子名称: 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V.
登録日2009-09-01
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献The crystal structure of the ribosome bound to EF-Tu and aminoacyl-tRNA.
Science, 326, 2009
1VZE
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L. CASEI THYMIDYLATE SYNTHASE MUTANT E60Q TERNARY COMPLEX WITH DUMP AND CB3717
分子名称: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
著者Birdsall, D.L, Finer-Moore, J, Stroud, R.M.
登録日1996-09-18
公開日1997-03-12
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The separate effects of E60Q in Lactobacillus casei thymidylate synthase delineate between mechanisms for formation of intermediates in catalysis.
Protein Eng., 11, 1998
1VZD
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L. CASEI THYMIDYLATE SYNTHASE MUTANT E60Q TERNARY COMPLEX WITH FDUMP AND CB3717
分子名称: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
著者Birdsall, D.L, Finer-Moore, J, Stroud, R.M.
登録日1996-09-18
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The separate effects of E60Q in Lactobacillus casei thymidylate synthase delineate between mechanisms for formation of intermediates in catalysis.
Protein Eng., 11, 1998
1VZA
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THYMIDYLATE SYNTHASE E60D MUTANT BINARY COMPLEX WITH 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
著者Birdsall, D.L, Finer-Moore, J, Stroud, R.M.
登録日1996-09-18
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The separate effects of E60Q in Lactobacillus casei thymidylate synthase delineate between mechanisms for formation of intermediates in catalysis.
Protein Eng., 11, 1998
1VZC
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L. CASEI THYMIDYLATE SYNTHASE MUTANT E60Q BINARY COMPLEX WITH FDUMP
分子名称: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
著者Birdsall, D.L, Finer-Moore, J, Stroud, R.M.
登録日1996-09-18
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The separate effects of E60Q in Lactobacillus casei thymidylate synthase delineate between mechanisms for formation of intermediates in catalysis.
Protein Eng., 11, 1998
4V5P
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The crystal structure of EF-Tu and A9C-tRNA-Trp bound to a near- cognate codon on the 70S ribosome
分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Schmeing, T.M, Voorhees, R.M, Ramakrishnan, V.
登録日2010-12-07
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献How Mutations in tRNA Distant from the Anticodon Affect the Fidelity of Decoding.
Nat.Struct.Mol.Biol., 18, 2011
4V8N
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The crystal structure of agmatidine tRNA-Ile2 bound to the 70S ribosome in the A and P site.
分子名称: 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ...
著者Voorhees, R.M, Mandal, D, Neubauer, C, Koehrer, C, RajBhandary, U.L, Ramakrishnan, V.
登録日2013-02-13
公開日2014-07-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The Structural Basis for Specific Decoding of Aua by Isoleucine tRNA on the Ribosome
Nat.Struct.Mol.Biol., 20, 2013
3LZ9
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The Crystal Structure of 5-epi-aristolochene synthase M4 mutant complexed with (2-trans,6-trans)-2-fluorofarnesyl diphosphate
分子名称: (2Z,6E)-2-fluoro-3,7,11-trimethyldodeca-2,6,10-trien-1-yl trihydrogen diphosphate, Aristolochene synthase, MAGNESIUM ION
著者Noel, J.P, Dellas, N, Faraldos, J.A, Zhao, M, Hess Jr, B.A, Smentek, L, Coates, R.M, O'Maille, P.E.
登録日2010-03-01
公開日2010-04-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates.
Acs Chem.Biol., 5, 2010
4GGM
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Structure of LpxI
分子名称: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, MAGNESIUM ION, UDP-2,3-diacylglucosamine pyrophosphatase LpxI
著者Metzger IV, L.E, Lee, J.K, Finer-Moore, J.S, Raetz, C.R.H, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP)
登録日2012-08-06
公開日2012-10-03
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.897 Å)
主引用文献LpxI structures reveal how a lipid A precursor is synthesized.
Nat.Struct.Mol.Biol., 19, 2012
1F09
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BU of 1f09 by Molmil
CRYSTAL STRUCTURE OF THE GREEN FLUORESCENT PROTEIN (GFP) VARIANT YFP-H148Q WITH TWO BOUND IODIDES
分子名称: GREEN FLUORESCENT PROTEIN, IODIDE ION
著者Wachter, R.M, Yarbrough, D, Kallio, K, Remington, S.J.
登録日2000-05-15
公開日2000-11-17
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Crystallographic and energetic analysis of binding of selected anions to the yellow variants of green fluorescent protein.
J.Mol.Biol., 301, 2000
4GEV
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E. coli thymidylate synthase Y209W variant in complex with substrate and a cofactor analog
分子名称: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-deoxy-5'-uridylic acid, Thymidylate synthase
著者Newby, Z, Lee, T.T, Finer-Moore, J, Stroud, R.M.
登録日2012-08-02
公開日2012-08-29
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献A remote mutation affects the hydride transfer by disrupting concerted protein motions in thymidylate synthase.
J.Am.Chem.Soc., 134, 2012
1VQB
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GENE V PROTEIN (SINGLE-STRANDED DNA BINDING PROTEIN)
分子名称: GENE V PROTEIN
著者Skinner, M.M, Zhang, H, Leschnitzer, D.H, Guan, Y, Bellamy, H, Sweet, R.M, Gray, C.W, Konings, R.N.H, Wang, A.H.-J, Terwilliger, T.C.
登録日1996-08-14
公開日1997-02-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the gene V protein of bacteriophage f1 determined by multiwavelength x-ray diffraction on the selenomethionyl protein.
Proc.Natl.Acad.Sci.USA, 91, 1994
1F0B
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BU of 1f0b by Molmil
CRYSTAL STRUCTURE OF THE GREEN FLUORESCENT PROTEIN (GFP) VARIANT YFP-H148Q
分子名称: GREEN FLUORESCENT PROTEIN
著者Wachter, R.M, Yarbrough, D, Kallio, K, Remington, S.J.
登録日2000-05-15
公開日2000-11-17
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallographic and energetic analysis of binding of selected anions to the yellow variants of green fluorescent protein.
J.Mol.Biol., 301, 2000
2BFZ
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Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH4.5 using 20mM ZnSO4 in buffer. 1mM DTT was used as a reducing agent. Cys221 is oxidized.
分子名称: AZIDE ION, BETA-LACTAMASE II, GLYCEROL, ...
著者Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
登録日2004-12-16
公開日2005-03-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism
Biochemistry, 44, 2005
4UY3
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Cytoplasmic domain of bacterial cell division protein ezra
分子名称: SEPTATION RING FORMATION REGULATOR EZRA
著者Cleverley, R.M, Barrett, J.R, Basle, A, Khai-Bui, N, Hewitt, L, Solovyova, A, Xu, Z, Daniela, R.A, Dixon, N.E, Harry, E.J, Oakley, A.J, Vollmer, W, Lewis, R.J.
登録日2014-08-28
公開日2014-10-22
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and Function of a Spectrin-Like Regulator of Bacterial Cytokinesis.
Nat.Commun., 5, 2014
4UXV
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Cytoplasmic domain of bacterial cell division protein EzrA
分子名称: SEPTATION RING FORMATION REGULATOR EZRA
著者Cleverley, R.M, Barrett, J.R, Basle, A, Khai-Bui, N, Hewitt, L, Solovyova, A, Xu, Z, Daniela, R.A, Dixon, N.E, Harry, E.J, Oakley, A.J, Vollmer, W, Lewis, R.J.
登録日2014-08-27
公開日2014-10-22
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.961 Å)
主引用文献Structure and Function of a Spectrin-Like Regulator of Bacterial Cytokinesis.
Nat.Commun., 5, 2014
1BTX
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Episelection: Novel Ki ~Nanomolar Inhibitors of Serine Proteases Selected by Binding or Chemistry on an Enzyme Surface
分子名称: BETA-TRYPSIN, CALCIUM ION, N-(tert-butoxycarbonyl)-L-alanyl-N-[(1S)-5-amino-1-(diethoxyboranyl)pentyl]-L-valinamide
著者Stroud, R.M, Katz, B.A, Finer-Moore, J.
登録日1995-05-17
公開日1995-10-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface.
Biochemistry, 34, 1995
3MLH
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BU of 3mlh by Molmil
Crystal structure of the 2009 H1N1 influenza virus hemagglutinin receptor-binding domain
分子名称: GLYCEROL, Hemagglutinin
著者DuBois, R.M, Aguilar-Yanez, J.M, Mendoza-Ochoa, G.I, Schultz-Cherry, S, Alvarez, M.M, White, S.W, Russell, C.J.
登録日2010-04-16
公開日2010-12-01
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The Receptor-Binding Domain of Influenza Virus Hemagglutinin Produced in Escherichia coli Folds into Its Native, Immunogenic Structure.
J.Virol., 85, 2011
2BFK
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Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH7 using 20mM ZnSO4 in buffer. 1mM DTT was used as a reducing agent
分子名称: AZIDE ION, BETA-LACTAMASE II, GLYCEROL, ...
著者Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
登録日2004-12-07
公開日2005-03-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism
Biochemistry, 44, 2005
2BG6
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Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH5 using 20 Micromolar ZnSO4 in the buffer. 1mM DTT was used as a reducing agent. Cys221 is oxidized.
分子名称: AZIDE ION, BETA-LACTAMASE II, GLYCEROL, ...
著者Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
登録日2004-12-17
公開日2005-03-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism
Biochemistry, 44, 2005
3LZU
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Crystal Structure of a Nelfinavir Resistant HIV-1 CRF01_AE Protease variant (N88S) in Complex with the Protease Inhibitor Darunavir.
分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, HIV-1 protease
著者Schiffer, C.A, Bandaranayake, R.M.
登録日2010-03-01
公開日2010-08-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献The Effect of Clade-Specific Sequence Polymorphisms on HIV-1 Protease Activity and Inhibitor Resistance Pathways.
J.Virol., 84, 2010
1FE2
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BU of 1fe2 by Molmil
CRYSTAL STRUCTURE OF DIHOMO-GAMMA-LINOLEIC ACID BOUND IN THE CYCLOOXYGENASE CHANNEL OF PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, EICOSA-8,11,14-TRIENOIC ACID, PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1, ...
著者Thuresson, E.D, Malkowski, M.G, Lakkides, K.M, Smith, W.L, Garavito, R.M.
登録日2000-07-20
公開日2001-05-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mutational and X-ray crystallographic analysis of the interaction of dihomo-gamma -linolenic acid with prostaglandin endoperoxide H synthases.
J.Biol.Chem., 276, 2001
1BTY
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BU of 1bty by Molmil
Crystal structure of beta-trypsin in complex with benzamidine
分子名称: BENZAMIDINE, BETA-TRYPSIN, CALCIUM ION
著者Stroud, R.M, Katz, B.A, Finer-Moore, J.
登録日1995-05-17
公開日1995-10-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface.
Biochemistry, 34, 1995
1BTZ
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Episelection: novel KI ~nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface
分子名称: BETA-TRYPSIN, CALCIUM ION, N-(tert-butoxycarbonyl)-L-alanyl-N-{(1R)-5-ammonio-1-[hydroxy(methoxy)boranyl]pentyl}-L-valinamide
著者Stroud, R.M, Katz, B.A, Finer-Moore, J.
登録日1995-05-17
公開日1995-10-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface.
Biochemistry, 34, 1995

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