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PDB: 2920 件

8CUZ
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KS-AT domains of mycobacterial Pks13 with inward AT conformation
分子名称: Polyketide synthase PKS13, UNKNOWN LIGAND
著者Kim, S.K, Dickinson, M.S, Finer-Moore, J.S, Rosenberg, O.S, Stroud, R.M.
登録日2022-05-17
公開日2023-02-15
最終更新日2023-03-29
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13.
Nat.Struct.Mol.Biol., 30, 2023
8CV1
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ACP1-KS-AT domains of mycobacterial Pks13
分子名称: Polyketide synthase PKS13, UNKNOWN LIGAND
著者Kim, S.K, Dickinson, M.S, Finer-Moore, J.S, Rosenberg, O.S, Stroud, R.M.
登録日2022-05-17
公開日2023-02-15
最終更新日2023-03-29
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13.
Nat.Struct.Mol.Biol., 30, 2023
1BTX
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Episelection: Novel Ki ~Nanomolar Inhibitors of Serine Proteases Selected by Binding or Chemistry on an Enzyme Surface
分子名称: BETA-TRYPSIN, CALCIUM ION, N-(tert-butoxycarbonyl)-L-alanyl-N-[(1S)-5-amino-1-(diethoxyboranyl)pentyl]-L-valinamide
著者Stroud, R.M, Katz, B.A, Finer-Moore, J.
登録日1995-05-17
公開日1995-10-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface.
Biochemistry, 34, 1995
1BTZ
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Episelection: novel KI ~nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface
分子名称: BETA-TRYPSIN, CALCIUM ION, N-(tert-butoxycarbonyl)-L-alanyl-N-{(1R)-5-ammonio-1-[hydroxy(methoxy)boranyl]pentyl}-L-valinamide
著者Stroud, R.M, Katz, B.A, Finer-Moore, J.
登録日1995-05-17
公開日1995-10-15
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface.
Biochemistry, 34, 1995
1BTY
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Crystal structure of beta-trypsin in complex with benzamidine
分子名称: BENZAMIDINE, BETA-TRYPSIN, CALCIUM ION
著者Stroud, R.M, Katz, B.A, Finer-Moore, J.
登録日1995-05-17
公開日1995-10-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface.
Biochemistry, 34, 1995
1BTW
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Episelection: novel KI ~nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface
分子名称: BETA-TRYPSIN, CALCIUM ION, N-(tert-butoxycarbonyl)-L-alanyl-N-{(1S)-5-ammonio-1-[hydroxy(3-hydroxypropoxy)boranyl]pentyl}-L-valinamide
著者Stroud, R.M, Katz, B.A, Finer-Moore, J.
登録日1995-05-17
公開日1995-10-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface.
Biochemistry, 34, 1995
4Q5W
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Crystal structure of extended-Tudor 9 of Drosophila melanogaster
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Maternal protein tudor
著者Ren, R, Liu, H, Wang, W, Wang, M, Yang, N, Dong, Y, Gong, W, Lehmann, R, Xu, R.M.
登録日2014-04-17
公開日2014-05-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Structure and domain organization of Drosophila Tudor
Cell Res., 24, 2014
4QF1
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Crystal structure of unliganded CH59UA, the inferred unmutated ancestor of the RV144 anti-HIV antibody lineage producing CH59
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CH59UA Fab fragment of heavy chain, CHLORIDE ION, ...
著者Wiehe, K, Easterhoff, D, Luo, K, Nicely, N.I, Bradley, T, Jaeger, F.H, Dennison, S.M, Zhang, R, Lloyd, K.E, Stolarchuk, C, Parks, R, Sutherland, L.L, Scearce, R.M, Morris, L, Kaewkungwal, J, Nitayaphan, S, Pitisuttithum, P, Rerks-Ngarm, S, Michael, N, Kim, J, Kelsoe, G, Montefiori, D.C, Tomaras, G, Bonsignori, M, Santra, S, Kepler, T.B, Alam, S.M, Moody, M.A, Liao, H.-X, Haynes, B.F.
登録日2014-05-19
公開日2015-02-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Antibody Light-Chain-Restricted Recognition of the Site of Immune Pressure in the RV144 HIV-1 Vaccine Trial Is Phylogenetically Conserved.
Immunity, 41, 2014
1C94
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REVERSING THE SEQUENCE OF THE GCN4 LEUCINE ZIPPER DOES NOT AFFECT ITS FOLD.
分子名称: RETRO-GCN4 LEUCINE ZIPPER
著者Mittl, P.R.E, Deillon, C.A, Sargent, D, Liu, N, Klauser, S, Thomas, R.M, Gutte, B, Gruetter, M.G.
登録日1999-07-30
公開日2000-03-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献The retro-GCN4 leucine zipper sequence forms a stable three-dimensional structure.
Proc.Natl.Acad.Sci.USA, 97, 2000
1BQ2
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E. COLI THYMIDYLATE SYNTHASE MUTANT N177A
分子名称: PHOSPHATE ION, THYMIDYLATE SYNTHASE
著者Reyes, C.L, Sage, C.R, Rutenber, E.E, Finer-Moore, J.S, Stroud, R.M.
登録日1998-08-20
公開日1999-04-27
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Inactivity of N229A thymidylate synthase due to water-mediated effects: isolating a late stage in methyl transfer.
J.Mol.Biol., 284, 1998
1BJ8
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THIRD N-TERMINAL DOMAIN OF GP130, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: GP130
著者Kernebeck, T, Pflanz, S, Muller-Newen, G, Kurapkat, G, Scheek, R.M, Dijkstra, K, Heinrich, P.C, Wollmer, A, Grzesiek, S, Grotzinger, J.
登録日1998-07-02
公開日1999-01-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The signal transducer gp130: solution structure of the carboxy-terminal domain of the cytokine receptor homology region.
Protein Sci., 8, 1999
4Q5Y
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Crystal structure of extended-Tudor 10-11 of Drosophila melanogaster
分子名称: Maternal protein tudor
著者Liu, H, Ren, R, Wang, W, Wang, M, Yang, N, Dong, Y, Gong, W, Lehmann, R, Xu, R.M.
登録日2014-04-18
公開日2014-05-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and domain organization of Drosophila Tudor
Cell Res., 24, 2014
1BJP
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CRYSTAL STRUCTURE OF 4-OXALOCROTONATE TAUTOMERASE INACTIVATED BY 2-OXO-3-PENTYNOATE AT 2.4 ANGSTROMS RESOLUTION
分子名称: 2-OXO-3-PENTENOIC ACID, 4-OXALOCROTONATE TAUTOMERASE
著者Taylor, A.B, Czerwinski, R.M, Johnson Junior, W.H, Whitman, C.P, Hackert, M.L.
登録日1998-06-26
公開日1998-12-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of 4-oxalocrotonate tautomerase inactivated by 2-oxo-3-pentynoate at 2.4 A resolution: analysis and implications for the mechanism of inactivation and catalysis.
Biochemistry, 37, 1998
4Q31
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The crystal structure of cystathione gamma lyase (CalE6) from Micromonospora echinospora
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FORMIC ACID, ...
著者Tan, K, Bigelow, L, Jedrzejczak, R, Babnigg, G, Bingman, C.A, Yennamalli, R.M, Singh, S, Kharel, M.K, Thorson, J.S, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2014-04-10
公開日2014-05-07
最終更新日2017-03-08
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Structural dynamics of a methionine gamma-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate.
Struct Dyn, 3, 2016
2INY
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Nanoporous Crystals of Chicken Embryo Lethal Orphan (CELO) Adenovirus Major Coat Protein, Hexon
分子名称: Hexon protein
著者Xu, L, Benson, S.D, Burnett, R.M.
登録日2006-10-09
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Nanoporous crystals of chicken embryo lethal orphan (CELO) adenovirus major coat protein, hexon.
J.Struct.Biol., 157, 2007
2J9F
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Human branched-chain alpha-ketoacid dehydrogenase-decarboxylase E1b
分子名称: 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, C2-1-HYDROXY-3-METHYL-PROPYL-THIAMIN DIPHOSPHATE, ...
著者Jun, L, Machius, M, Chuang, J.L, Wynn, R.M, Chuang, D.T.
登録日2006-11-07
公開日2007-02-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献The Two Active Sites in Human Branched-Chain Alpha- Keto Acid Dehydrogenase Operate Independently without an Obligatory Alternating-Site Mechanism.
J.Biol.Chem., 282, 2007
2MCV
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Solid-state NMR structure of piscidin 1 in aligned 1:1 phosphatidylethanolamine/phosphoglycerol lipid bilayers
分子名称: Moronecidin
著者Fu, R, Tian, Y, Perrin Jr, B.S, Grant, C.V, Hayden, R.M, Pastor, R.W, Cotten, M.L.
登録日2013-08-27
公開日2014-01-22
最終更新日2014-03-19
実験手法SOLID-STATE NMR
主引用文献High-resolution structures and orientations of antimicrobial peptides piscidin 1 and piscidin 3 in fluid bilayers reveal tilting, kinking, and bilayer immersion.
J.Am.Chem.Soc., 136, 2014
1P2Z
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Refinement of Adenovirus Type 2 Hexon with CNS
分子名称: CITRIC ACID, Hexon protein
著者Rux, J.J, Kuser, P.R, Burnett, R.M.
登録日2003-04-16
公開日2003-11-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and phylogenetic analysis of adenovirus hexons by use of high-resolution x-ray crystallographic, molecular modeling, and sequence-based methods
J.VIROL., 77, 2003
1PGG
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PROSTAGLANDIN H2 SYNTHASE-1 COMPLEXED WITH 1-(4-IODOBENZOYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID (IODOINDOMETHACIN), TRANS MODEL
分子名称: 1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Loll, P.J, Picot, D, Garavito, R.M.
登録日1995-12-02
公開日1997-01-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site.
Biochemistry, 35, 1996
1PGF
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PROSTAGLANDIN H2 SYNTHASE-1 COMPLEXED WITH 1-(4-IODOBENZOYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID (IODOINDOMETHACIN), CIS MODEL
分子名称: 1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Loll, P.J, Picot, D, Garavito, R.M.
登録日1995-12-02
公開日1997-01-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Synthesis and use of iodinated nonsteroidal antiinflammatory drug analogs as crystallographic probes of the prostaglandin H2 synthase cyclooxygenase active site.
Biochemistry, 35, 1996
1GW7
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QUASI-ATOMIC RESOLUTION MODEL OF BACTERIOPHAGE PRD1 CAPSID, OBTAINED BY COMBINED CRYO-EM AND X-RAY CRYSTALLOGRAPHY.
分子名称: MAJOR CAPSID PROTEIN
著者San Martin, C, Huiskonen, J, Bamford, J.K.H, Butcher, S.J, Fuller, S.D, Bamford, D.H, Burnett, R.M.
登録日2002-03-08
公開日2002-03-13
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (13.5 Å)
主引用文献Minor Proteins, Mobile Arms, and Membrane-Capsid Interactions in Bacteriophage Prd1 Capsid Assembly
Nat.Struct.Biol., 9, 2002
1GBT
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STRUCTURE OF AN ACYL-ENZYME INTERMEDIATE DURING CATALYSIS: (GUANIDINOBENZOYL) TRYPSIN
分子名称: 4-carbamimidamidobenzoic acid, BETA-TRYPSIN, CALCIUM ION, ...
著者Singer, P.T, Sweet, R.M.
登録日1991-09-17
公開日1994-01-31
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of an acyl-enzyme intermediate during catalysis: (guanidinobenzoyl)trypsin.
Biochemistry, 29, 1990
1GW8
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quasi-atomic resolution model of bacteriophage PRD1 sus607 mutant, obtained by combined cryo-EM and X-ray crystallography.
分子名称: MAJOR CAPSID PROTEIN
著者San Martin, C, Huiskonen, J, Bamford, J.K.H, Butcher, S.J, Fuller, S.D, Bamford, D.H, Burnett, R.M.
登録日2002-03-08
公開日2002-03-15
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (13.3 Å)
主引用文献Minor Proteins, Mobile Arms and Membrane-Capsid Interactions in the Bacteriophage Prd1 Capsid.
Nat.Struct.Biol., 9, 2002
1HX6
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P3, THE MAJOR COAT PROTEIN OF THE LIPID-CONTAINING BACTERIOPHAGE PRD1.
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, MAJOR CAPSID PROTEIN, ...
著者Benson, S.D, Bamford, J.K.H, Bamford, D.H, Burnett, R.M.
登録日2001-01-11
公開日2001-01-24
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The X-ray crystal structure of P3, the major coat protein of the lipid-containing bacteriophage PRD1, at 1.65 A resolution.
Acta Crystallogr.,Sect.D, 58, 2002
1HQN
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THE SELENOMETHIONINE DERIVATIVE OF P3, THE MAJOR COAT PROTEIN OF THE LIPID-CONTAINING BACTERIOPHAGE PRD1.
分子名称: MAJOR CAPSID PROTEIN
著者Benson, S.D, Bamford, J.K.H, Bamford, D.H, Burnett, R.M.
登録日2000-12-18
公開日2001-01-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The X-ray crystal structure of P3, the major coat protein of the lipid-containing bacteriophage PRD1, at 1.65 A resolution.
Acta Crystallogr.,Sect.D, 58, 2002

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