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PDB: 2920 件

6E1M
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Structure of AtTPC1(DDE) reconstituted in saposin A
分子名称: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CALCIUM ION, PALMITIC ACID, ...
著者Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M.
登録日2018-07-10
公開日2018-09-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E1P
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Structure of AtTPC1(DDE) in state 2
分子名称: CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1
著者Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M.
登録日2018-07-10
公開日2018-09-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
2G8X
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Escherichia coli Y209W apoprotein
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CARBONATE ION, PHOSPHATE ION, ...
著者Lee, T.T, Finer-Moore, J.S, Stroud, R.M.
登録日2006-03-03
公開日2006-03-14
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献The role of protein dynamics in thymidylate synthase catalysis: Variants of conserved dUMP-binding Tyr-261
TO BE PUBLISHED
1TDC
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STRUCTURES OF THYMIDYLATE SYNTHASE WITH A C-TERMINAL DELETION: ROLE OF THE C-TERMINUS IN ALIGNMENT OF D/UMP AND CH2H4FOLATE
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
著者Perry, K.M, Carreras, C.W, Chang, L.C, Santi, D.V, Stroud, R.M.
登録日1993-02-15
公開日1993-07-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structures of thymidylate synthase with a C-terminal deletion: role of the C-terminus in alignment of 2'-deoxyuridine 5'-monophosphate and 5,10-methylenetetrahydrofolate.
Biochemistry, 32, 1993
1TDA
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STRUCTURES OF THYMIDYLATE SYNTHASE WITH A C-TERMINAL DELETION: ROLE OF THE C-TERMINUS IN ALIGNMENT OF D/UMP AND CH2H4FOLATE
分子名称: PHOSPHATE ION, THYMIDYLATE SYNTHASE
著者Perry, K.M, Carreras, C.W, Chang, L.C, Santi, D.V, Stroud, R.M.
登録日1993-02-15
公開日1993-07-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Structures of thymidylate synthase with a C-terminal deletion: role of the C-terminus in alignment of 2'-deoxyuridine 5'-monophosphate and 5,10-methylenetetrahydrofolate.
Biochemistry, 32, 1993
2EVU
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BU of 2evu by Molmil
Crystal structure of aquaporin AqpM at 2.3A resolution
分子名称: Aquaporin aqpM, GLYCEROL, octyl beta-D-glucopyranoside
著者Lee, J.K, Kozono, D, Remis, J, Kitagawa, Y, Agre, P, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP)
登録日2005-10-31
公開日2005-12-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for conductance by the archaeal aquaporin AqpM at 1.68 A.
Proc.Natl.Acad.Sci.Usa, 102, 2005
1NJE
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THYMIDYLATE SYNTHASE WITH 2'-DEOXYCYTIDINE 5'-MONOPHOSPHATE (DCMP)
分子名称: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
著者Finer-Moore, J, Stroud, R.M.
登録日1996-01-23
公開日1996-07-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Partitioning roles of side chains in affinity, orientation, and catalysis with structures for mutant complexes: asparagine-229 in thymidylate synthase.
Biochemistry, 35, 1996
1N7U
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THE RECEPTOR-BINDING PROTEIN P2 OF BACTERIOPHAGE PRD1: CRYSTAL FORM I
分子名称: ACETATE ION, Adsorption protein P2, CALCIUM ION
著者Xu, L, Benson, S.D, Butcher, S.J, Bamford, D.H, Burnett, R.M.
登録日2002-11-18
公開日2003-04-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Receptor Binding Protein P2 of PRD1, a Virus Targeting Antibiotic-Resistant Bacteria, Has a Novel Fold Suggesting Multiple Functions.
Structure, 11, 2003
6FO6
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CryoEM structure of bovine cytochrome bc1 in complex with the anti-malarial inhibitor SCR0911
分子名称: 7-methoxy-3-methyl-2-[5-[4-(trifluoromethyloxy)phenyl]pyridin-3-yl]quinolin-4-ol, Cytochrome b, Cytochrome b-c1 complex subunit 1, ...
著者Johnson, R.M, Amporndanai, K, O'Neill, P.M, Fishwick, C.W.G, Jamson, A.H, Rawson, S.D, Hasnain, S.S, Antonyuk, S.V, Muench, S.P.
登録日2018-02-06
公開日2018-02-28
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献X-ray and cryo-EM structures of inhibitor-bound cytochromebc1complexes for structure-based drug discovery.
IUCrJ, 5, 2018
6GAL
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BU of 6gal by Molmil
Structure of fully reduced Hydrogenase (Hyd-1) variant E28Q collected at pH 10
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, CHLORIDE ION, FE3-S4 CLUSTER, ...
著者Carr, S.B, Armstrong, F.A, Evans, R.M.
登録日2018-04-11
公開日2019-02-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Mechanistic Exploitation of a Self-Repairing, Blocked Proton Transfer Pathway in an O2-Tolerant [NiFe]-Hydrogenase.
J. Am. Chem. Soc., 140, 2018
2BGA
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Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH7 using 20 Micromolar ZnSO4 in the buffer. 1mM DTT was used as a reducing agent. Cys221 is oxidized.
分子名称: AZIDE ION, BETA-LACTAMASE II, GLYCEROL, ...
著者Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
登録日2004-12-17
公開日2005-03-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism
Biochemistry, 44, 2005
2G89
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L. casei thymidylate synthase Y261A in complex with substrate, dUMP
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, thymidylate synthase
著者Finer-Moore, J.S, Stroud, R.M.
登録日2006-03-02
公開日2006-03-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261
Biochemistry, 45, 2006
6FPI
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BU of 6fpi by Molmil
Structure of fully reduced Hydrogenase (Hyd-1) variant E28Q
分子名称: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, FE3-S4 CLUSTER, ...
著者Carr, S.B, Armstrong, F.A, Evans, R.M.
登録日2018-02-09
公開日2018-12-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Mechanistic Exploitation of a Self-Repairing, Blocked Proton Transfer Pathway in an O2-Tolerant [NiFe]-Hydrogenase.
J. Am. Chem. Soc., 140, 2018
1TDB
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BU of 1tdb by Molmil
STRUCTURES OF THYMIDYLATE SYNTHASE WITH A C-TERMINAL DELETION: ROLE OF THE C-TERMINUS IN ALIGNMENT OF D/UMP AND CH2H4FOLATE
分子名称: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
著者Perry, K.M, Carreras, C.W, Chang, L.C, Santi, D.V, Stroud, R.M.
登録日1993-02-15
公開日1993-07-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structures of thymidylate synthase with a C-terminal deletion: role of the C-terminus in alignment of 2'-deoxyuridine 5'-monophosphate and 5,10-methylenetetrahydrofolate.
Biochemistry, 32, 1993
6G9Z
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Crystal structure of human histidine triad nucleotide-binding protein 1 (hHINT1) crystallized at P212121 space group, with visible extended fragment of N-terminus
分子名称: (2S)-2-hydroxybutanedioic acid, Histidine triad nucleotide-binding protein 1
著者Dolot, R.M, Seda, A, Nawrot, B.C.
登録日2018-04-11
公開日2018-04-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Differences in crystal packing as the key factor for stabilization of the N-terminal fragment of hHINT1 protein
To Be Published
2GFA
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double tudor domain complex structure
分子名称: Jumonji domain-containing protein 2A, peptide
著者Huang, Y, Fang, J, Bedford, M.T, Zhang, Y, Xu, R.M.
登録日2006-03-21
公開日2006-05-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A
Science, 312, 2006
2G86
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L. casei thymidylate synthase Y261F in complex with substrate, dUMP
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase
著者Finer-Moore, J.S, Stroud, R.M.
登録日2006-03-01
公開日2006-03-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261
Biochemistry, 45, 2006
2BH2
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BU of 2bh2 by Molmil
Crystal Structure of E. coli 5-methyluridine methyltransferase RumA in complex with ribosomal RNA substrate and S-adenosylhomocysteine.
分子名称: 23S RIBOSOMAL RNA 1932-1968, 23S RRNA (URACIL-5-)-METHYLTRANSFERASE RUMA, IRON/SULFUR CLUSTER, ...
著者Lee, T.T, Agarwalla, S, Stroud, R.M.
登録日2005-01-06
公開日2005-03-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A Unique RNA Fold in the Ruma-RNA-Cofactor Ternary Complex Contributes to Substrate Selectivity and Enzymatic Function
Cell(Cambridge,Mass.), 120, 2005
2G8D
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Lactobacillus casei thymidylate synthase Y261W-dUMP complex
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, thymidylate synthase
著者Finer-Moore, J.S, Stroud, R.M.
登録日2006-03-02
公開日2006-03-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261
Biochemistry, 45, 2006
1N7V
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BU of 1n7v by Molmil
THE RECEPTOR-BINDING PROTEIN P2 OF BACTERIOPHAGE PRD1: CRYSTAL FORM III
分子名称: ACETATE ION, Adsorption protein P2, CALCIUM ION
著者Xu, L, Benson, S.D, Butcher, S.J, Bamford, D.H, Burnett, R.M.
登録日2002-11-18
公開日2003-04-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Receptor Binding Protein P2 of PRD1, a Virus Targeting Antibiotic-Resistant Bacteria, Has a Novel Fold Suggesting Multiple Functions.
Structure, 11, 2003
2BG8
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BU of 2bg8 by Molmil
Bacillus cereus metallo-beta-lactamase (BcII) Arg (121) Cys mutant. Solved at pH4.5 using 20 Micromolar ZnSO4 in the buffer. 1mM DTT and 1mM TCEP-HCl were used as reducing agents.
分子名称: BETA-LACTAMASE II, GLYCEROL, SULFATE ION, ...
著者Davies, A.M, Rasia, R.M, Vila, A.J, Sutton, B.J, Fabiane, S.M.
登録日2004-12-17
公開日2005-03-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Effect of Ph on the Active Site of an Arg121Cys Mutant of the Metallo-Beta-Lactamase from Bacillus Cereus: Implications for the Enzyme Mechanism
Biochemistry, 44, 2005
2GF1
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BU of 2gf1 by Molmil
SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR 1: A NUCLEAR MAGNETIC RESONANCE AND RESTRAINED MOLECULAR DYNAMICS STUDY
分子名称: INSULIN-LIKE GROWTH FACTOR I
著者Cooke, R.M, Harvey, T.S, Campbell, I.D.
登録日1991-01-23
公開日1993-04-15
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study.
Biochemistry, 30, 1991
1NJB
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BU of 1njb by Molmil
THYMIDYLATE SYNTHASE
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
著者Finer-Moore, J, Stroud, R.M.
登録日1996-01-23
公開日1996-10-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Partitioning roles of side chains in affinity, orientation, and catalysis with structures for mutant complexes: asparagine-229 in thymidylate synthase.
Biochemistry, 35, 1996
2GSM
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Catalytic Core (Subunits I and II) of Cytochrome c oxidase from Rhodobacter sphaeroides
分子名称: CADMIUM ION, CALCIUM ION, COPPER (II) ION, ...
著者Qin, L, Hiser, C, Mulichak, A, Garavito, R.M, Ferguson-Miller, S.
登録日2006-04-26
公開日2006-10-10
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification of conserved lipid/detergent-binding sites in a high-resolution structure of the membrane protein cytochrome c oxidase.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1NJC
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THYMIDYLATE SYNTHASE, MUTATION, N229D WITH 2'-DEOXYCYTIDINE 5'-MONOPHOSPHATE (DCMP)
分子名称: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
著者Finer-Moore, J, Stroud, R.M.
登録日1996-01-23
公開日1996-07-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Partitioning roles of side chains in affinity, orientation, and catalysis with structures for mutant complexes: asparagine-229 in thymidylate synthase.
Biochemistry, 35, 1996

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