3NGT
 
 | | Structure of Leishmania NDKb complexed with AMP. | | 分子名称: | ADENOSINE MONOPHOSPHATE, Nucleoside diphosphate kinase | | 著者 | Trindade, D.M, Sousa, T.A.C.B, Tonoli, C.C.C, Santos, C.R, Arni, R.K, Ward, R.J, Oliveira, A.H.C, Murakami, M.T. | | 登録日 | 2010-06-13 | | 公開日 | 2011-04-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Molecular adaptability of nucleoside diphosphate kinase b from trypanosomatid parasites: stability, oligomerization and structural determinants of nucleotide binding.
Mol Biosyst, 7, 2011
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5WBN
 | | Crystal structure of fragment 3-(3-Benzyl-2-oxo-2H-[1,2,4]triazino[2,3-c]quinazolin-6-yl)propanoic acid bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain | | 分子名称: | 3-(3-benzyl-2-oxo-2H-[1,2,4]triazino[2,3-c]quinazolin-6-yl)propanoic acid, ACETATE ION, CHLORIDE ION, ... | | 著者 | Harding, R.J, Walker, J.R, Ferreira de Freitas, R, Ravichandran, M, Santhakumar, V, Schapira, M, Bountra, C, Edwards, A.M, Arrowsmith, C.H. | | 登録日 | 2017-06-29 | | 公開日 | 2017-08-02 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Crystal structure of fragment 3-(3-Benzyl-2-oxo-2H-[1,2,4]triazino[2,3-c]quinazolin-6-yl)propanoic acid bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain
To be published
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1YYE
 | | Crystal structure of estrogen receptor beta complexed with way-202196 | | 分子名称: | 3-(3-FLUORO-4-HYDROXYPHENYL)-7-HYDROXY-1-NAPHTHONITRILE, Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1 | | 著者 | Mewshaw, R.E, Edsall Jr, R.J, Yang, C, Manas, E.S, Xu, Z.B, Henderson, R.A, Keith Jr, J.C, Harris, H.A. | | 登録日 | 2005-02-24 | | 公開日 | 2006-02-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | ERbeta ligands. 3. Exploiting two binding orientations of the 2-phenylnaphthalene scaffold to achieve ERbeta selectivity
J.Med.Chem., 48, 2005
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3NGU
 | | Structure of Leishmania NDKb complexed with ADP. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Nucleoside diphosphate kinase | | 著者 | Trindade, D.M, Sousa, T.A.C.B, Tonoli, C.C.C, Santos, C.R, Arni, R.K, Ward, R.J, Oliveira, A.H.C, Murakami, M.T. | | 登録日 | 2010-06-13 | | 公開日 | 2011-04-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Molecular adaptability of nucleoside diphosphate kinase b from trypanosomatid parasites: stability, oligomerization and structural determinants of nucleotide binding.
Mol Biosyst, 7, 2011
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3NGR
 | | Crystal structure of Leishmania nucleoside diphosphate kinase b with unordered nucleotide-binding loop. | | 分子名称: | Nucleoside diphosphate kinase, PHOSPHATE ION | | 著者 | Trindade, D.M, Sousa, T.A.C.B, Tonoli, C.C.C, Santos, C.R, Arni, R.K, Ward, R.J, Oliveira, A.H.C, Murakami, M.T. | | 登録日 | 2010-06-13 | | 公開日 | 2011-04-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Molecular adaptability of nucleoside diphosphate kinase b from trypanosomatid parasites: stability, oligomerization and structural determinants of nucleotide binding.
Mol Biosyst, 7, 2011
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1ZAF
 | | Crystal structure of estrogen receptor beta complexed with 3-Bromo-6-hydroxy-2-(4-hydroxy-phenyl)-inden-1-one | | 分子名称: | 3-BROMO-6-HYDROXY-2-(4-HYDROXYPHENYL)-1H-INDEN-1-ONE, Estrogen receptor beta, Nuclear receptor coactivator 1 | | 著者 | McDevitt, R.E, Malamas, M.S, Manas, E.S, Unwalla, R.J, Xu, Z.B, Miller, C.P, Harris, H.A. | | 登録日 | 2005-04-06 | | 公開日 | 2006-04-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Estrogen receptor ligands: design and synthesis of new 2-arylindene-1-ones
Bioorg.Med.Chem.Lett., 15, 2005
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1ZBL
 | | Bacillus halodurans RNase H catalytic domain mutant D192N in complex with 12-mer RNA/DNA hybrid | | 分子名称: | 5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3', 5'-R(*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*C)-3', MAGNESIUM ION, ... | | 著者 | Nowotny, M, Gaidamakov, S.A, Crouch, R.J, Yang, W. | | 登録日 | 2005-04-08 | | 公開日 | 2005-07-12 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structures of RNase H Bound to an RNA/DNA Hybrid: Substrate Specificity and Metal-Dependent Catalysis.
Cell(Cambridge,Mass.), 121, 2005
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5WPB
 | | Crystal structure of fragment 3-(3-(pyridin-2-ylmethoxy)quinoxalin-2-yl)propanoic acid bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain | | 分子名称: | 3-{3-[(pyridin-2-yl)methoxy]quinoxalin-2-yl}propanoic acid, Histone deacetylase 6, UNKNOWN ATOM OR ION, ... | | 著者 | Harding, R.J, Tempel, W, Ferreira de Freitas, R, Franzoni, I, Ravichandran, M, Lautens, M, Santhakumar, V, Schapira, M, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | | 登録日 | 2017-08-04 | | 公開日 | 2017-08-23 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin.
J. Med. Chem., 60, 2017
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3NAU
 | | Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2) | | 分子名称: | SULFATE ION, Zinc fingers and homeoboxes protein 2 | | 著者 | Ren, J, Bird, L.E, Owens, R.J, Stammers, D.K, Oxford Protein Production Facility (OPPF) | | 登録日 | 2010-06-02 | | 公開日 | 2010-07-07 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains
Bmc Struct.Biol., 10, 2010
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5WWQ
 | | Crystal structure of human NSun6 | | 分子名称: | Putative methyltransferase NSUN6 | | 著者 | Liu, R.J, Long, T, Wang, E.D. | | 登録日 | 2017-01-04 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.815 Å) | | 主引用文献 | Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6
Nucleic Acids Res., 45, 2017
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1ZM0
 | | Crystal Structure of the Carboxyl Terminal PH Domain of Pleckstrin To 2.1 Angstroms | | 分子名称: | Pleckstrin | | 著者 | Jackson, S.G, Zhang, Y, Zhang, K, Summerfield, R, Haslam, R.J, Junop, M.S. | | 登録日 | 2005-05-09 | | 公開日 | 2006-02-28 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of the carboxy-terminal PH domain of pleckstrin at 2.1 Angstroms.
Acta Crystallogr.,Sect.D, 62, 2006
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1ZNE
 | | Strong Solute-Solute Dispersive Interactions in a Protein-Ligand Complex | | 分子名称: | CADMIUM ION, HEXAN-1-OL, Major Urinary Protein | | 著者 | Malham, R, Johnstone, S, Bingham, R.J, Barratt, E, Phillips, S.E, Laughton, C.A, Homans, S.W. | | 登録日 | 2005-05-11 | | 公開日 | 2005-12-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Strong Solute-Solute Dispersive Interactions in a Protein-Ligand Complex.
J.Am.Chem.Soc., 127, 2005
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1ZNL
 | | Strong Solute-Solute Dispersive Interactions in a Protein-Ligand Complex | | 分子名称: | CADMIUM ION, DECAN-1-OL, Major Urinary Protein | | 著者 | Malham, R, Johnstone, S, Bingham, R.J, Barratt, E, Phillips, S.E, Laughton, C.A, Homans, S.W. | | 登録日 | 2005-05-11 | | 公開日 | 2005-12-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Strong Solute-Solute Dispersive Interactions in a Protein-Ligand Complex.
J.Am.Chem.Soc., 127, 2005
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5WWR
 | | Crystal structure of human NSun6/tRNA/SFG | | 分子名称: | Putative methyltransferase NSUN6, SINEFUNGIN, tRNA | | 著者 | Liu, R.J, Long, T, Wang, E.D. | | 登録日 | 2017-01-04 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.096 Å) | | 主引用文献 | Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6
Nucleic Acids Res., 45, 2017
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1ZYQ
 | | T7 DNA polymerase in complex with 8oG and incoming ddATP | | 分子名称: | 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*CP*CP*(8OG)P*CP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*(DDG))-3', ... | | 著者 | Brieba, L.G, Kokoska, R.J, Bebenek, K, Kunkel, T.A, Ellenberger, T. | | 登録日 | 2005-06-10 | | 公開日 | 2005-11-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A lysine residue in the fingers subdomain of t7 DNA polymerase modulates the miscoding potential of 8-oxo-7,8-dihydroguanosine.
Structure, 13, 2005
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1MLC
 | | MONOCLONAL ANTIBODY FAB D44.1 RAISED AGAINST CHICKEN EGG-WHITE LYSOZYME COMPLEXED WITH LYSOZYME | | 分子名称: | HEN EGG WHITE LYSOZYME, IGG1-KAPPA D44.1 FAB (HEAVY CHAIN), IGG1-KAPPA D44.1 FAB (LIGHT CHAIN) | | 著者 | Braden, B.C, Souchon, H, Eisele, J.-L, Bentley, G.A, Bhat, T.N, Navaza, J, Poljak, R.J. | | 登録日 | 1995-03-10 | | 公開日 | 1995-06-03 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Three-dimensional structures of the free and the antigen-complexed Fab from monoclonal anti-lysozyme antibody D44.1.
J.Mol.Biol., 243, 1994
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3NMJ
 | | Crystal structure of a nickel mediated dimer for the phenanthroline-modified cytochrome cb562 variant, MBP-Phen2 | | 分子名称: | N-1,10-phenanthrolin-5-ylacetamide, NICKEL (II) ION, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Radford, R.J, Tezcan, F.A. | | 登録日 | 2010-06-22 | | 公開日 | 2010-11-24 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Porous protein frameworks with unsaturated metal centers in sterically encumbered coordination sites.
Chem.Commun.(Camb.), 47, 2011
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3NMI
 | | Crystal structure of the phenanthroline-modified cytochrome cb562 variant, MBP-Phen2 | | 分子名称: | ACETATE ION, N-1,10-phenanthrolin-5-ylacetamide, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Radford, R.J, Tezcan, F.A. | | 登録日 | 2010-06-22 | | 公開日 | 2010-11-24 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Porous protein frameworks with unsaturated metal centers in sterically encumbered coordination sites.
Chem.Commun.(Camb.), 47, 2011
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3NQS
 | | Crystal Structure of Inducible Nitric Oxide Synthase with N-Nitrosated-pterin | | 分子名称: | 1,2-ETHANEDIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE, ... | | 著者 | Rosenfeld, R.J, Getzoff, E.D, Tainer, J.A. | | 登録日 | 2010-06-29 | | 公開日 | 2010-07-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Nitric-oxide synthase forms N-NO-pterin and S-NO-cys: implications for activity, allostery, and regulation.
J.Biol.Chem., 285, 2010
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7MHT
 | | CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX | | 分子名称: | 5'-D(P*CP*CP*AP*TP*GP*AP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ... | | 著者 | O'Gara, M, Horton, J.R, Roberts, R.J, Cheng, X. | | 登録日 | 1998-08-05 | | 公開日 | 1998-11-30 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
Nat.Struct.Biol., 5, 1998
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3NWA
 | | Glycoprotein B from Herpes simplex virus type 1, W174R mutant, low-pH | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein B, MESO-ERYTHRITOL | | 著者 | Stampfer, S.D, Lou, H, Cohen, G.H, Eisenberg, R.J, Heldwein, E.E. | | 登録日 | 2010-07-09 | | 公開日 | 2010-12-01 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2629 Å) | | 主引用文献 | Structural basis of local, pH-dependent conformational changes in glycoprotein B from herpes simplex virus type 1.
J.Virol., 84, 2010
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5WWT
 | | Crystal structure of human NSun6/tRNA | | 分子名称: | Putative methyltransferase NSUN6, tRNA | | 著者 | Liu, R.J, Long, T, Wang, E.D. | | 登録日 | 2017-01-04 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.197 Å) | | 主引用文献 | Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6
Nucleic Acids Res., 45, 2017
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5WWS
 | | Crystal structure of human NSun6/tRNA/SAM | | 分子名称: | Putative methyltransferase NSUN6, S-ADENOSYLMETHIONINE, tRNA | | 著者 | Liu, R.J, Long, T, Wang, E.D. | | 登録日 | 2017-01-04 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.247 Å) | | 主引用文献 | Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6
Nucleic Acids Res., 45, 2017
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1MLB
 | | MONOCLONAL ANTIBODY FAB D44.1 RAISED AGAINST CHICKEN EGG-WHITE LYSOZYME | | 分子名称: | IGG1-KAPPA D44.1 FAB (HEAVY CHAIN), IGG1-KAPPA D44.1 FAB (LIGHT CHAIN) | | 著者 | Braden, B.C, Souchon, H, Eisele, J.-L, Bentley, G.A, Bhat, T.N, Navaza, J, Poljak, R.J. | | 登録日 | 1995-03-08 | | 公開日 | 1995-06-03 | | 最終更新日 | 2013-09-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Three-dimensional structures of the free and the antigen-complexed Fab from monoclonal anti-lysozyme antibody D44.1.
J.Mol.Biol., 243, 1994
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3NT5
 | | Crystal structure of myo-inositol dehydrogenase from Bacillus subtilis with bound cofactor and product inosose | | 分子名称: | (2R,3S,4s,5R,6S)-2,3,4,5,6-pentahydroxycyclohexanone, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase, ... | | 著者 | Van Straaten, K.E, Palmer, D.R.J, Sanders, D.A.R. | | 登録日 | 2010-07-02 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.9006 Å) | | 主引用文献 | Structural investigation of myo-inositol dehydrogenase from Bacillus subtilis: implications for catalytic mechanism and inositol dehydrogenase subfamily classification.
Biochem.J., 432, 2010
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