6ML2
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![BU of 6ml2 by Molmil](/molmil-images/mine/6ml2) | ZBTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 1) | Descriptor: | DNA (5'-D(*AP*CP*GP*CP*AP*GP*GP*TP*CP*CP*TP*GP*GP*CP*AP*GP*CP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*GP*CP*TP*GP*CP*CP*AP*GP*GP*AP*CP*CP*TP*GP*CP*G)-3'), ZINC ION, ... | Authors: | Horton, J.R, Cheng, X, Ren, R. | Deposit date: | 2018-09-26 | Release date: | 2019-07-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.874 Å) | Cite: | Structural basis of specific DNA binding by the transcription factor ZBTB24. Nucleic Acids Res., 47, 2019
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6MLT
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![BU of 6mlt by Molmil](/molmil-images/mine/6mlt) | Crystal structure of the V. cholerae biofilm matrix protein Bap1 | Descriptor: | CALCIUM ION, CITRATE ANION, GLYCEROL, ... | Authors: | Kaus, K, Biester, A, Chupp, E, Lu, K, Vidsudharomn, C, Olson, R. | Deposit date: | 2018-09-28 | Release date: | 2019-08-28 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The 1.9 angstrom crystal structure of the extracellular matrix protein Bap1 fromVibrio choleraeprovides insights into bacterial biofilm adhesion. J.Biol.Chem., 294, 2019
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1TWD
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![BU of 1twd by Molmil](/molmil-images/mine/1twd) | Crystal Structure of the Putative Copper Homeostasis Protein (CutC) from Shigella flexneri, Northeast Structural Genomics Target SfR33 | Descriptor: | Copper homeostasis protein cutC | Authors: | Forouhar, F, Lee, I, Vorobiev, S.M, Ma, L.-C, Shastry, R, Conover, K, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-06-30 | Release date: | 2004-07-20 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of the Putative Copper Homeostasis Protein (CutC) from Shigella flexneri, Northeast Structural Genomics Target SfR33 To be Published
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4R3R
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![BU of 4r3r by Molmil](/molmil-images/mine/4r3r) | Crystal structures of EGFR in complex with Mig6 | Descriptor: | Epidermal growth factor receptor, peptide from ERBB receptor feedback inhibitor 1' | Authors: | Park, E, Kim, N, Yi, Z, Cho, A, Kim, K, Ficarro, S.B, Park, A, Park, W.Y, Murray, B, Meyerson, M, Beroukim, R, Marto, J.A, Cho, J, Eck, M.J. | Deposit date: | 2014-08-17 | Release date: | 2015-08-12 | Last modified: | 2015-09-16 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6. Nat.Struct.Mol.Biol., 22, 2015
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6MY4
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![BU of 6my4 by Molmil](/molmil-images/mine/6my4) | Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98M,HC-G99M,LC-S30bR] | Descriptor: | 1,2-ETHANEDIOL, anti-VEGF-A Fab fragment bH1 heavy chain, anti-VEGF-A Fab fragment bH1 light chain | Authors: | Shi, R, Picard, M.-E, Manenda, M. | Deposit date: | 2018-11-01 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Binding symmetry and surface flexibility mediate antibody self-association. Mabs, 11, 2019
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3R9D
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![BU of 3r9d by Molmil](/molmil-images/mine/3r9d) | CDK2 in complex with inhibitor RC-2-135 | Descriptor: | 4-amino-N-(3-fluorophenyl)-2-[(4-sulfamoylphenyl)amino]-1,3-thiazole-5-carboxamide, Cyclin-dependent kinase 2 | Authors: | Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. | Deposit date: | 2011-03-25 | Release date: | 2012-10-31 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases. J.Med.Chem., 56, 2013
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6N7X
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![BU of 6n7x by Molmil](/molmil-images/mine/6n7x) | S. cerevisiae U1 snRNP | Descriptor: | 56 kDa U1 small nuclear ribonucleoprotein component, Pre-mRNA-processing factor 39, Protein NAM8, ... | Authors: | Li, X, Liu, S, Jiang, J, Zhang, L, Espinosa, S, Hill, R.C, Hansen, K.C, Zhou, Z.H, Zhao, R. | Deposit date: | 2018-11-28 | Release date: | 2019-07-24 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing. Nat Commun, 8, 2017
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1TZ9
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![BU of 1tz9 by Molmil](/molmil-images/mine/1tz9) | Crystal Structure of the Putative Mannonate Dehydratase from Enterococcus faecalis, Northeast Structural Genomics Target EfR41 | Descriptor: | Mannonate dehydratase | Authors: | Forouhar, F, Chen, Y, Xiao, R, Cooper, B, Shastry, R, Acton, T.A, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-07-09 | Release date: | 2004-07-20 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal Structure of the Putative Mannonate Dehydratase from Enterococcus faecalis, Northeast Structural Genomics Target EfR41 To be Published
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6MH0
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![BU of 6mh0 by Molmil](/molmil-images/mine/6mh0) | Crystal Structure of the New Deli Metallo Beta Lactamase Variant 3 from Klebsiella pneumoniae | Descriptor: | CHLORIDE ION, Metallo-beta-lactamase NDM-3, SULFATE ION, ... | Authors: | Kim, Y, Tesar, C, Jedrzejczak, R, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2018-09-16 | Release date: | 2018-10-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal Structure of the New Deli Metallo Beta Lactamase Variant 3 from Klebsiella pneumoniae To Be Published
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6MH8
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![BU of 6mh8 by Molmil](/molmil-images/mine/6mh8) | High-viscosity injector-based Pink Beam Serial Crystallography of Micro-crystals at a Synchrotron Radiation Source | Descriptor: | 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Adenosine receptor A2a, Soluble cytochrome b562 chimeric construct | Authors: | Martin-Garcia, J.M, Zhu, L, Mendez, D, Lee, M, Chun, E, Li, C, Hu, H, Subramanian, G, Kissick, D, Ogata, C, Henning, R, Ishchenko, A, Dobson, Z, Zhan, S, Weierstall, U, Spence, J.C.H, Fromme, P, Zatsepin, N.A, Fischetti, R.F, Cherezov, V, Liu, W. | Deposit date: | 2018-09-17 | Release date: | 2019-04-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | High-viscosity injector-based pink-beam serial crystallography of microcrystals at a synchrotron radiation source. Iucrj, 6, 2019
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6MKJ
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![BU of 6mkj by Molmil](/molmil-images/mine/6mkj) | Crystal structure of penicillin binding protein 5 (PBP5) from Enterococcus faecium in the closed conformation | Descriptor: | penicillin binding protein 5 (PBP5) | Authors: | Moon, T.M, Soares, A, D'Andrea, E.D, Jaconcic, J, Peti, W, Page, R. | Deposit date: | 2018-09-25 | Release date: | 2018-10-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.864 Å) | Cite: | The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance. J. Biol. Chem., 293, 2018
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6ML9
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![BU of 6ml9 by Molmil](/molmil-images/mine/6ml9) | Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) D30A mutant from Salmonella typhimurium complexed with arginine | Descriptor: | ACETATE ION, ARGININE, GLYCEROL, ... | Authors: | Romero-Romero, S, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A. | Deposit date: | 2018-09-27 | Release date: | 2019-08-07 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.687 Å) | Cite: | The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein. Febs J., 287, 2020
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6MLN
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![BU of 6mln by Molmil](/molmil-images/mine/6mln) | Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) S72A mutant from Salmonella typhimurium complexed with arginine | Descriptor: | ACETATE ION, ARGININE, GLYCEROL, ... | Authors: | Romero-Romero, S, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A. | Deposit date: | 2018-09-27 | Release date: | 2019-08-07 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.721 Å) | Cite: | The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein. Febs J., 287, 2020
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6MKI
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![BU of 6mki by Molmil](/molmil-images/mine/6mki) | Crystal structure of penicillin-binding protein 4 (PBP4) from Enterococcus faecalis in the ceftaroline-bound form | Descriptor: | Ceftaroline, bound form, GLYCEROL, ... | Authors: | D'Andrea, E.D, Moon, T.M, Peti, W, Page, R. | Deposit date: | 2018-09-25 | Release date: | 2018-10-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.984 Å) | Cite: | The structures of penicillin-binding protein 4 (PBP4) and PBP5 fromEnterococciprovide structural insights into beta-lactam resistance. J. Biol. Chem., 293, 2018
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6MKU
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![BU of 6mku by Molmil](/molmil-images/mine/6mku) | Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) D11A mutant from Salmonella typhimurium complexed with arginine | Descriptor: | ACETATE ION, ARGININE, GLYCEROL, ... | Authors: | Romero-Romero, S, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A. | Deposit date: | 2018-09-26 | Release date: | 2019-08-07 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.727 Å) | Cite: | The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein. Febs J., 287, 2020
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6ML7
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![BU of 6ml7 by Molmil](/molmil-images/mine/6ml7) | ZBTB24 Zinc Fingers 4-8 with 19+1mer DNA Oligonucleotide (Sequence 4 with a CpG 5mC Modification) | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*AP*CP*GP*CP*AP*GP*GP*TP*CP*CP*TP*GP*GP*AP*(5CM)P*GP*AP*AP*TP*T)-3'), ... | Authors: | Horton, J.R, Cheng, X, Ren, R. | Deposit date: | 2018-09-26 | Release date: | 2019-07-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural basis of specific DNA binding by the transcription factor ZBTB24. Nucleic Acids Res., 47, 2019
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6MNU
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![BU of 6mnu by Molmil](/molmil-images/mine/6mnu) | Crystal structure of Yersinia pestis UDP-glucose pyrophosphorylase | Descriptor: | 1,2-ETHANEDIOL, UTP--glucose-1-phosphate uridylyltransferase | Authors: | Gibbs, M.E, Lountos, G.T, Gumpena, R, Waugh, D.S. | Deposit date: | 2018-10-03 | Release date: | 2019-09-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.172 Å) | Cite: | Crystal structure of UDP-glucose pyrophosphorylase from Yersinia pestis, a potential therapeutic target against plague. Acta Crystallogr.,Sect.F, 75, 2019
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1UE0
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![BU of 1ue0 by Molmil](/molmil-images/mine/1ue0) | Isoleucyl-tRNA synthetase editing domain complexed with L-Valine | Descriptor: | Isoleucyl-tRNA synthetase, VALINE | Authors: | Fukunaga, R, Fukai, S, Ishitani, R, Nureki, O, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-05-08 | Release date: | 2004-03-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the CP1 domain from Thermus thermophilus isoleucyl-tRNA synthetase and its complex with L-valine. J.Biol.Chem., 279, 2004
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2J4Z
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![BU of 2j4z by Molmil](/molmil-images/mine/2j4z) | Structure of Aurora-2 in complex with PHA-680626 | Descriptor: | 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE, ARSENIC, SERINE THREONINE-PROTEIN KINASE 6 | Authors: | Cameron, A.D, Izzo, G, Storici, P, Rusconi, L, Fancelli, D, Varasi, M, Berta, D, Bindi, S, Forte, B, Severino, D, Tonani, R, Vianello, P. | Deposit date: | 2006-09-08 | Release date: | 2006-11-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | 1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile. J. Med. Chem., 49, 2006
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6HAP
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![BU of 6hap by Molmil](/molmil-images/mine/6hap) | Adenylate kinase | Descriptor: | Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE | Authors: | Kantaev, R, Inbal, R, Goldenzweig, A, Barak, Y, Dym, O, Peleg, Y, Albek, S, Fleishman, S.J, Haran, G. | Deposit date: | 2018-08-08 | Release date: | 2019-08-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Manipulating the Folding Landscape of a Multidomain Protein. J.Phys.Chem.B, 122, 2018
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5MX3
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![BU of 5mx3 by Molmil](/molmil-images/mine/5mx3) | |
5MMK
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![BU of 5mmk by Molmil](/molmil-images/mine/5mmk) | HYL-20 | Descriptor: | GLY-ILE-LEU-SER-SER-LEU-TRP-LYS-LYS-LEU-LYS-LYS-ILE-ILE-ALA-LYS | Authors: | Hexnerova, R. | Deposit date: | 2016-12-10 | Release date: | 2017-09-06 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | How proteases from Enterococcus faecalis contribute to its resistance to short alpha-helical antimicrobial peptides. Pathog Dis, 75, 2017
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5MML
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![BU of 5mml by Molmil](/molmil-images/mine/5mml) | HYL-20k | Descriptor: | GLY-ILE-LEU-SER-SER-LEU-TRP-LYS-LYS-LEU-LYS-LYS-ILE-ILE-ALA-LYS | Authors: | Hexnerova, R. | Deposit date: | 2016-12-10 | Release date: | 2017-09-06 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | How proteases from Enterococcus faecalis contribute to its resistance to short alpha-helical antimicrobial peptides. Pathog Dis, 75, 2017
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5MZW
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![BU of 5mzw by Molmil](/molmil-images/mine/5mzw) | Crystal structure of the decarboxylase AibA/AibB | Descriptor: | GLYCEROL, Glutaconate CoA-transferase family, subunit A, ... | Authors: | Bock, T, Luxenburger, E, Hoffmann, J, Schuetza, V, Feiler, C, Mueller, R, Blankenfeldt, W. | Deposit date: | 2017-02-02 | Release date: | 2017-05-31 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | AibA/AibB Induces an Intramolecular Decarboxylation in Isovalerate Biosynthesis by Myxococcus xanthus. Angew. Chem. Int. Ed. Engl., 56, 2017
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6N81
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![BU of 6n81 by Molmil](/molmil-images/mine/6n81) | |