7OPK
 
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8OTM
 | | structure of InhA from mycobacterium tuberculosis in complex with N-((1-(3-hydroxy-4-phenoxybenzyl)-1H-1,2,3-triazol-4-yl)methyl)-2-oxo-2H-chromene-3-carboxamide | | Descriptor: | 1,2-ETHANEDIOL, 2-oxidanylidene-~{N}-[[1-[(3-oxidanyl-4-phenoxy-phenyl)methyl]-1,2,3-triazol-4-yl]methyl]chromene-3-carboxamide, ACETATE ION, ... | | Authors: | Chebaiki, M, Maveyraud, L, Tamhaev, R, Lherbet, C, Mourey, L. | | Deposit date: | 2023-04-21 | | Release date: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Discovery of new diaryl ether inhibitors against Mycobacterium tuberculosis targeting the minor portal of InhA.
Eur.J.Med.Chem., 259, 2023
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7OLW
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7OLN
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5FJB
 | | Cyclophilin A Stabilize HIV-1 Capsid through a Novel Non- canonical Binding Site | | Descriptor: | GAG POLYPROTEIN, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A | | Authors: | Liu, C, Perilla, J.R, Ning, J, Lu, M, Hou, G, Ramalhu, R, Bedwell, G.J, Ahn, J, Shi, J, Gronenborn, A.M, Prevelige Jr, P.E, Rousso, I, Aiken, C, Polenova, T, Schulten, K, Zhang, P. | | Deposit date: | 2015-10-07 | | Release date: | 2016-03-16 | | Last modified: | 2017-08-23 | | Method: | ELECTRON MICROSCOPY (9 Å) | | Cite: | Cyclophilin a Stabilizes the HIV-1 Capsid Through a Novel Non-Canonical Binding Site.
Nat.Commun., 7, 2016
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1PNB
 | | STRUCTURE OF NAPIN BNIB, NMR, 10 STRUCTURES | | Descriptor: | NAPIN BNIB | | Authors: | Rico, M, Bruix, M, Gonzalez, C, Monsalve, R, Rodriguez, R. | | Deposit date: | 1996-09-17 | | Release date: | 1997-09-17 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | 1H NMR assignment and global fold of napin BnIb, a representative 2S albumin seed protein.
Biochemistry, 35, 1996
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7OLU
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6YTL
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6YU7
 | | Crystal structure of MhsT in complex with L-tyrosine | | Descriptor: | DODECYL-BETA-D-MALTOSIDE, SODIUM ION, Sodium-dependent transporter, ... | | Authors: | Focht, D, Neumann, C, Lyons, J, Eguskiza Bilbao, A, Blunck, R, Malinauskaite, L, Schwarz, I.O, Javitch, J.A, Quick, M, Nissen, P. | | Deposit date: | 2020-04-25 | | Release date: | 2020-07-15 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | A non-helical region in transmembrane helix 6 of hydrophobic amino acid transporter MhsT mediates substrate recognition.
Embo J., 40, 2021
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8OTN
 | | structure of InhA from mycobacterium tuberculosis in complex with inhibitor 7-((1-(3-Hydroxy-4-phenoxybenzyl)-1H-1,2,3-triazol-4-yl)methoxy)-4-methyl-2H-chromen-2-one | | Descriptor: | 4-methyl-7-[[1-[(3-oxidanyl-4-phenoxy-phenyl)methyl]-1,2,3-triazol-4-yl]methoxy]chromen-2-one, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Chebaiki, M, Maveyraud, L, Tamhaev, R, Lherbet, C, Mourey, L. | | Deposit date: | 2023-04-21 | | Release date: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.962 Å) | | Cite: | Discovery of new diaryl ether inhibitors against Mycobacterium tuberculosis targeting the minor portal of InhA.
Eur.J.Med.Chem., 259, 2023
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5GR5
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7OOM
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6ZG0
 | | SARM1 SAM1-2 domains | | Descriptor: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y. | | Deposit date: | 2020-06-18 | | Release date: | 2020-11-11 | | Last modified: | 2020-12-09 | | Method: | ELECTRON MICROSCOPY (7.7 Å) | | Cite: | Structural basis for SARM1 inhibition and activation under energetic stress.
Elife, 9, 2020
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7OPT
 | | Crystal structure of Trypanosoma cruzi peroxidase | | Descriptor: | Ascorbate peroxidase, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Freeman, S.L, Kwon, H, Skafar, V, Fielding, A.J, Martinez, A, Piacenza, L, Radi, R, Raven, E.L. | | Deposit date: | 2021-06-01 | | Release date: | 2022-06-08 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Crystal structure of Trypanosoma cruzi heme peroxidase and characterization of its substrate specificity and compound I intermediate.
J.Biol.Chem., 298, 2022
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7PB9
 | | Crystal structure of tandem WH domains of Vps25 from Odinarchaeota | | Descriptor: | Tandem WH domains of Vps25 | | Authors: | Salzer, R, Bellini, D, Papatziamou, D, Robinson, N.P, Lowe, J. | | Deposit date: | 2021-08-01 | | Release date: | 2022-06-08 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Asgard archaea shed light on the evolutionary origins of the eukaryotic ubiquitin-ESCRT machinery.
Nat Commun, 13, 2022
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8P0O
 | | Crystal structure of AaNGT complexed to UDP-Gal | | Descriptor: | 1,2-ETHANEDIOL, Adhesin, GALACTOSE-URIDINE-5'-DIPHOSPHATE | | Authors: | Pinello, B, Macias-Leon, J, Rovira, C, Hurtado-Guerrero, R. | | Deposit date: | 2023-05-10 | | Release date: | 2023-09-06 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Molecular basis for bacterial N-glycosylation by a soluble HMW1C-like N-glycosyltransferase.
Nat Commun, 14, 2023
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8P0Q
 | | Crystal structure of AaNGT complexed to UDP and a peptide | | Descriptor: | Adhesin, PHE-GLY-ASN-TRP-THR-THR, URIDINE-5'-DIPHOSPHATE | | Authors: | Piniello, B, Macias-Leon, J, Rovira, C, Hurtado-Guerrero, R. | | Deposit date: | 2023-05-10 | | Release date: | 2023-09-06 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Molecular basis for bacterial N-glycosylation by a soluble HMW1C-like N-glycosyltransferase.
Nat Commun, 14, 2023
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7NWD
 | | Three-quartet c-kit2 G-quadruplex stabilized by a pyrene conjugate | | Descriptor: | POTASSIUM ION, c-kit2_py1 | | Authors: | Peterkova, K, Durnik, I, Marek, R, Plavec, J, Podbevsek, P. | | Deposit date: | 2021-03-16 | | Release date: | 2021-08-04 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | c-kit2 G-quadruplex stabilized via a covalent probe: exploring G-quartet asymmetry.
Nucleic Acids Res., 49, 2021
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6ZQE
 | | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-A (Poly-Ala) | | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | | Authors: | Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R. | | Deposit date: | 2020-07-09 | | Release date: | 2020-09-23 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (7.1 Å) | | Cite: | 90 S pre-ribosome transformation into the primordial 40 S subunit.
Science, 369, 2020
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7A2B
 | | X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant Q207D | | Descriptor: | MAGNESIUM ION, R-specific alcohol dehydrogenase | | Authors: | Bischoff, D, Hermann, J, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. | | Deposit date: | 2020-08-17 | | Release date: | 2020-10-28 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.399 Å) | | Cite: | Controlling Protein Crystallization by Free Energy Guided Design of Interactions at Crystal Contacts
Crystals, 11, 2021
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7A5J
 | | Structure of the split human mitoribosomal large subunit with P-and E-site mt-tRNAs | | Descriptor: | 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... | | Authors: | Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. | | Deposit date: | 2020-08-21 | | Release date: | 2020-12-23 | | Last modified: | 2023-03-15 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Elongational stalling activates mitoribosome-associated quality control.
Science, 370, 2020
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5GQX
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5GNV
 | | Structure of PSD-95/MAP1A complex reveals unique target recognition mode of MAGUK GK domain | | Descriptor: | Disks large homolog 4, Microtubule-associated protein 1A, SULFATE ION | | Authors: | Shang, Y, Xia, Y, Zhu, R, Zhu, J. | | Deposit date: | 2016-07-25 | | Release date: | 2017-08-02 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.596 Å) | | Cite: | Structure of the PSD-95/MAP1A complex reveals a unique target recognition mode of the MAGUK GK domain
Biochem. J., 474, 2017
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6ZQC
 | | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Pre-A1 | | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | | Authors: | Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R. | | Deposit date: | 2020-07-09 | | Release date: | 2020-09-23 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | 90 S pre-ribosome transformation into the primordial 40 S subunit.
Science, 369, 2020
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5GQW
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