7RY1
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![BU of 7ry1 by Molmil](/molmil-images/mine/7ry1) | human Hsp90_MC domain structure | Descriptor: | Heat shock protein HSP 90-alpha, N-[2-(1-MALEIMIDYL)ETHYL]-7-DIETHYLAMINOCOUMARIN-3-CARBOXAMIDE | Authors: | Peng, S, Deng, J, Matts, R. | Deposit date: | 2021-08-24 | Release date: | 2022-05-11 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.523 Å) | Cite: | Crystal structure of the middle and C-terminal domains of Hsp90 alpha labeled with a coumarin derivative reveals a potential allosteric binding site as a drug target. Acta Crystallogr D Struct Biol, 78, 2022
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5SNP
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5SN8
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5SO4
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![BU of 5so4 by Molmil](/molmil-images/mine/5so4) | |
5SND
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5SNQ
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5SNS
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5Y78
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![BU of 5y78 by Molmil](/molmil-images/mine/5y78) | Crystal structure of the triose-phosphate/phosphate translocator in complex with inorganic phosphate | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PHOSPHATE ION, Putative hexose phosphate translocator | Authors: | Lee, Y, Nishizawa, T, Takemoto, M, Kumazaki, K, Yamashita, K, Hirata, K, Minoda, A, Nagatoishi, S, Tsumoto, K, Ishitani, R, Nureki, O. | Deposit date: | 2017-08-16 | Release date: | 2017-10-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity Nat Plants, 3, 2017
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5T9R
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![BU of 5t9r by Molmil](/molmil-images/mine/5t9r) | Structure of rabbit RyR1 (Ca2+-only dataset, class 3) | Descriptor: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ... | Authors: | Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. | Deposit date: | 2016-09-09 | Release date: | 2016-10-12 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (5.8 Å) | Cite: | Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
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5TB0
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![BU of 5tb0 by Molmil](/molmil-images/mine/5tb0) | Structure of rabbit RyR1 (EGTA-only dataset, all particles) | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION | Authors: | Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. | Deposit date: | 2016-09-10 | Release date: | 2016-10-12 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
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8A29
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![BU of 8a29 by Molmil](/molmil-images/mine/8a29) | Apo 1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa | Descriptor: | 1-deoxy-D-xylulose-5-phosphate synthase, CALCIUM ION, CHLORIDE ION, ... | Authors: | Hamid, R, Adam, S, Lacour, A, Monjas, L, Hirsch, A. | Deposit date: | 2022-06-02 | Release date: | 2023-06-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | 1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding. J.Biol.Chem., 299, 2023
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5Y8P
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![BU of 5y8p by Molmil](/molmil-images/mine/5y8p) | Mycobacterium tuberculosis 3-Hydroxyisobutyrate dehydrogenase (MtHIBADH) + 3-Hydroxy propionate (3-HP) | Descriptor: | (2~{S})-2-methylpentanedioic acid, 3-HYDROXY-PROPANOIC ACID, ACRYLIC ACID, ... | Authors: | Srikalaivani, R, Singh, A, Surolia, A, Vijayan, M. | Deposit date: | 2017-08-21 | Release date: | 2018-07-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure, interactions and action ofMycobacterium tuberculosis3-hydroxyisobutyric acid dehydrogenase. Biochem. J., 475, 2018
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5XXX
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![BU of 5xxx by Molmil](/molmil-images/mine/5xxx) | GMPCPP-microtubule complexed with nucleotide-free KIF5C | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ... | Authors: | Morikawa, M, Shigematsu, H, Nitta, R, Hirokawa, N. | Deposit date: | 2017-07-05 | Release date: | 2018-10-10 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (6.43 Å) | Cite: | Kinesin-binding-triggered conformation switching of microtubules contributes to polarized transport J. Cell Biol., 217, 2018
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5XZC
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![BU of 5xzc by Molmil](/molmil-images/mine/5xzc) | Cryo-EM structure of p300-p53 protein complex | Descriptor: | Cellular tumor antigen p53, Histone acetyltransferase p300 | Authors: | Ghosh, R, Roy, S, Sengupta, J. | Deposit date: | 2017-07-12 | Release date: | 2019-01-23 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (10.7 Å) | Cite: | Tumor suppressor p53-mediated structural reorganization of the transcriptional coactivator p300. Biochemistry, 2019
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7SEK
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![BU of 7sek by Molmil](/molmil-images/mine/7sek) | Solution structure of the zinc finger domain of murine MetAP1, complexed with ZNG N-terminal peptide | Descriptor: | COBW domain-containing protein 1,Methionine aminopeptidase 1 fusion, ZINC ION | Authors: | Edmonds, K.A, Jordan, M.R, Thalluri, K, Wu, H, Di Marchi, R, Giedroc, D.P. | Deposit date: | 2021-09-30 | Release date: | 2022-06-01 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis. Cell, 185, 2022
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8A36
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7ZTH
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![BU of 7zth by Molmil](/molmil-images/mine/7zth) | Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the open conformation | Descriptor: | DNA (48-MER), PLP-dependent aminotransferase family protein | Authors: | Freda, I, Montemiglio, L.C, Tramonti, A, Contestabile, R, Vallone, B, Exertier, C, Savino, C, Chaves Sanjuan, A, Bolognesi, M. | Deposit date: | 2022-05-10 | Release date: | 2023-07-05 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR. Nucleic Acids Res., 51, 2023
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8A39
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![BU of 8a39 by Molmil](/molmil-images/mine/8a39) | Crystal Structure of PaaX from Escherichia coli W | Descriptor: | DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive, GLYCEROL, ... | Authors: | Molina, R, Alba-Perez, A, Hermoso, J.A. | Deposit date: | 2022-06-07 | Release date: | 2023-07-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural characterization of PaaX, the main repressor of the phenylacetate degradation pathway in Escherichia coli W: A novel fold of transcription regulator proteins. Int.J.Biol.Macromol., 254, 2024
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5TAS
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![BU of 5tas by Molmil](/molmil-images/mine/5tas) | Structure of rabbit RyR1 (Caffeine/ATP/EGTA dataset, class 1) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... | Authors: | Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. | Deposit date: | 2016-09-10 | Release date: | 2016-10-12 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
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5TB8
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8A4D
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8A45
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7ZN5
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![BU of 7zn5 by Molmil](/molmil-images/mine/7zn5) | Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the closed conformation, C2 symmetry. | Descriptor: | DNA (48-MER), PLP-dependent aminotransferase family protein | Authors: | Freda, I, Montemiglio, L.C, Tramonti, A, Contestabile, R, Vallone, B, Exertier, C, Savino, C, Chaves Sanjuan, A, Bolognesi, M. | Deposit date: | 2022-04-20 | Release date: | 2023-07-05 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR. Nucleic Acids Res., 51, 2023
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8A33
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7ZLA
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![BU of 7zla by Molmil](/molmil-images/mine/7zla) | Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the half-closed conformation | Descriptor: | DNA (48-MER), PLP-dependent aminotransferase family protein | Authors: | Freda, I, Montemiglio, L.C, Tramonti, A, Contestabile, R, Vallone, B, Savino, C, Exertier, C, Bolognesi, M, Chaves Sanjuan, A. | Deposit date: | 2022-04-14 | Release date: | 2023-07-05 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.99 Å) | Cite: | Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR. Nucleic Acids Res., 51, 2023
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