7ZLA

Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the half-closed conformation

Summary for 7ZLA

Entry DOI	10.2210/pdb7zla/pdb
Related	7PQ9
EMDB information	14778
Descriptor	PLP-dependent aminotransferase family protein, DNA (48-MER) (3 entities in total)
Functional Keywords	transcription factor, plp-binding protein, domain-swap homodimer, dna binding protein
Biological source	Alkalihalobacillus clausii More
Total number of polymer chains	4
Total formula weight	140560.30
Authors	Freda, I.,Montemiglio, L.C.,Tramonti, A.,Contestabile, R.,Vallone, B.,Savino, C.,Exertier, C.,Bolognesi, M.,Chaves Sanjuan, A. (deposition date: 2022-04-14, release date: 2023-07-05, Last modification date: 2024-01-17)
Primary citation	Freda, I.,Exertier, C.,Barile, A.,Chaves-Sanjuan, A.,Vega, M.V.,Isupov, M.N.,Harmer, N.J.,Gugole, E.,Swuec, P.,Bolognesi, M.,Scipioni, A.,Savino, C.,Di Salvo, M.L.,Contestabile, R.,Vallone, B.,Tramonti, A.,Montemiglio, L.C. Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR. Nucleic Acids Res., 51:8237-8254, 2023 Cited by PubMed: 37378428 DOI: 10.1093/nar/gkad552 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.99 Å)

Structure validation