1OMI
| Crystal structure of PrfA,the transcriptional regulator in Listeria monocytogenes | Descriptor: | GLYCEROL, Listeriolysin regulatory protein | Authors: | Thirumuruhan, R, Rajashankar, K, Fedorov, A.A, Dodatko, T, Chance, M.R, Cossart, P, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2003-02-25 | Release date: | 2003-03-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of PrfA, the transcriptional regulator in Listeria monocytogenes To be Published
|
|
7OBF
| |
6ZG1
| SARM1 SAM1-2 domains | Descriptor: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y. | Deposit date: | 2020-06-18 | Release date: | 2020-11-11 | Last modified: | 2020-12-09 | Method: | ELECTRON MICROSCOPY (3.77 Å) | Cite: | Structural basis for SARM1 inhibition and activation under energetic stress. Elife, 9, 2020
|
|
6XUS
| RNA dodecamer with a 6-hydrazino-2-aminopurine modified base | Descriptor: | MAGNESIUM ION, RNA dodecamer with a 6-hydrazino-2-aminopurine modified base, SODIUM ION | Authors: | Ennifar, E, Micura, R, Gasser, C, Brillet, K. | Deposit date: | 2020-01-21 | Release date: | 2021-02-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Thioguanosine Conversion Enables mRNA-Lifetime Evaluation by RNA Sequencing Using Double Metabolic Labeling (TUC-seq DUAL). Angew.Chem.Int.Ed.Engl., 59, 2020
|
|
3IXM
| |
3BAW
| Human pancreatic alpha-amylase complexed with azide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AZIDE ION, CALCIUM ION, ... | Authors: | Maurus, R, Brayer, G.D. | Deposit date: | 2007-11-08 | Release date: | 2008-03-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Alternative catalytic anions differentially modulate human alpha-amylase activity and specificity Biochemistry, 47, 2008
|
|
7OT4
| |
7OXN
| Crystal Structure of TAP01 in complex with cyclised amyloid beta peptide | Descriptor: | 1,2-ETHANEDIOL, Amyloid-beta precursor protein, TAP01 family antibody heavy chain, ... | Authors: | Hall, G, Cowan, R, Carr, M.D. | Deposit date: | 2021-06-22 | Release date: | 2022-06-29 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Discovery of a novel pseudo beta-hairpin structure of N-truncated amyloid-beta for use as a vaccine against Alzheimer's disease. Mol Psychiatry, 27, 2022
|
|
6XX7
| Arabidopsis thaliana Casein Kinase 2 (CK2) alpha-1 crystal in complex with ANP | Descriptor: | CHLORIDE ION, Casein kinase II subunit alpha-1, MAGNESIUM ION, ... | Authors: | Demulder, M, De Veylder, L, Loris, R. | Deposit date: | 2020-01-27 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of Arabidopsis thaliana casein kinase 2 alpha 1. Acta Crystallogr.,Sect.F, 76, 2020
|
|
7OQR
| Crystal structure of Trypanosoma cruzi peroxidase | Descriptor: | ACETATE ION, Ascorbate peroxidase, GLYCEROL, ... | Authors: | Freeman, S.L, Kwon, H, Skafar, V, Fielding, A.J, Martinez, A, Piacenza, L, Radi, R, Raven, E.L. | Deposit date: | 2021-06-04 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal structure of Trypanosoma cruzi heme peroxidase and characterization of its substrate specificity and compound I intermediate. J.Biol.Chem., 298, 2022
|
|
8P4Y
| Coiled-coil protein origami triangle | Descriptor: | GLYCEROL, Protein origami triangle | Authors: | Satler, T, Hadzi, S, Jerala, R. | Deposit date: | 2023-05-23 | Release date: | 2023-08-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.052 Å) | Cite: | Crystal Structure of de Novo Designed Coiled-Coil Protein Origami Triangle. J.Am.Chem.Soc., 145, 2023
|
|
8OR6
| |
7OW1
| Crystal Structure of TAP01 in complex with amyloid beta peptide | Descriptor: | Amyloid-beta precursor protein, CITRATE ANION, TAP01 family antibody heavy chain, ... | Authors: | Hall, G, Cowan, R, Carr, M.D. | Deposit date: | 2021-06-16 | Release date: | 2022-06-29 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Discovery of a novel pseudo beta-hairpin structure of N-truncated amyloid-beta for use as a vaccine against Alzheimer's disease. Mol Psychiatry, 27, 2022
|
|
6Z5N
| DnaJB1 JD-GF | Descriptor: | DnaJ homolog subfamily B member 1 | Authors: | Avraham-Abayev, M, London, N, Rosenzweig, R. | Deposit date: | 2020-05-27 | Release date: | 2020-11-18 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | HSP40 proteins use class-specific regulation to drive HSP70 functional diversity. Nature, 587, 2020
|
|
8OSD
| Crystal structure of the titin domain Fn3-49 | Descriptor: | Titin | Authors: | Nikoopour, R, Rees, M, Gautel, M. | Deposit date: | 2023-04-18 | Release date: | 2023-08-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation. J.Struct.Biol., 215, 2023
|
|
8OS3
| Crystal structure of the titin domain Fn3-11 | Descriptor: | Titin | Authors: | Nikoopour, R, Rees, M, Gautel, M. | Deposit date: | 2023-04-17 | Release date: | 2023-08-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation. J.Struct.Biol., 215, 2023
|
|
8OT5
| Crystal structure of the titin domain Fn3-85 | Descriptor: | CHLORIDE ION, SODIUM ION, Titin | Authors: | Nikoopour, R, Rees, M, Gautel, M. | Deposit date: | 2023-04-20 | Release date: | 2023-08-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation. J.Struct.Biol., 215, 2023
|
|
8OTY
| Crystal structure of the titin domain Fn3-90 | Descriptor: | Titin | Authors: | Nikoopour, R, Rees, M, Gautel, M. | Deposit date: | 2023-04-21 | Release date: | 2023-08-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation. J.Struct.Biol., 215, 2023
|
|
6ZRT
| Crystal structure of SARS CoV2 main protease in complex with inhibitor Telaprevir | Descriptor: | (1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(2R,3S)-1-(cyclopropylamino)-2-hydroxy-1-oxohexan-3-yl]octahydrocyclopenta[c]pyrrole-1-carboxamide, DIMETHYL SULFOXIDE, Main Protease | Authors: | Oerlemans, R, Wang, W, Lunev, S, Domling, A, Groves, M.R. | Deposit date: | 2020-07-14 | Release date: | 2020-08-12 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Repurposing the HCV NS3-4A protease drug boceprevir as COVID-19 therapeutics. Rsc Med Chem, 12, 2020
|
|
8P0P
| Crystal structure of AaNGT complexed to UDP-2F-Glucose | Descriptor: | Adhesin, URIDINE-5'-DIPHOSPHATE, URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GLUCOSE | Authors: | Piniello, B, Macias-Leon, J, Rovira, C, Hurtado-Guerrero, R. | Deposit date: | 2023-05-10 | Release date: | 2023-09-06 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Molecular basis for bacterial N-glycosylation by a soluble HMW1C-like N-glycosyltransferase. Nat Commun, 14, 2023
|
|
6ZS5
| 3.5 A cryo-EM structure of human uromodulin filament core | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Stanisich, J.J, Zyla, D, Afanasyev, P, Xu, J, Pilhofer, M, Boeringer, D, Glockshuber, R. | Deposit date: | 2020-07-15 | Release date: | 2020-09-02 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The cryo-EM structure of the human uromodulin filament core reveals a unique assembly mechanism. Elife, 9, 2020
|
|
8ORP
| Crystal structure of Drosophila melanogaster alpha-amylase in complex with the inhibitor acarbose | Descriptor: | 1,2-ETHANEDIOL, 4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ... | Authors: | Aghajari, N, Haser, R. | Deposit date: | 2023-04-16 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and Functional Characterization of Drosophila melanogaster alpha-Amylase. Molecules, 28, 2023
|
|
6ZU9
| Structure of a yeast ABCE1-bound 48S initiation complex | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | Authors: | Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | Deposit date: | 2020-07-22 | Release date: | 2020-10-28 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
|
|
6ZXF
| Cryo-EM structure of a late human pre-40S ribosomal subunit - State G | Descriptor: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | Authors: | Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. | Deposit date: | 2020-07-29 | Release date: | 2020-12-02 | Last modified: | 2020-12-09 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020
|
|
6ZQA
| Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state A (Poly-Ala) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R. | Deposit date: | 2020-07-09 | Release date: | 2020-09-23 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | 90 S pre-ribosome transformation into the primordial 40 S subunit. Science, 369, 2020
|
|