7OXN
Crystal Structure of TAP01 in complex with cyclised amyloid beta peptide
Summary for 7OXN
| Entry DOI | 10.2210/pdb7oxn/pdb |
| Related | 7OW1 |
| Descriptor | TAP01 family antibody heavy chain, TAP01 family antibody light chain, Amyloid-beta precursor protein, ... (6 entities in total) |
| Functional Keywords | alzheimer's disease, immune system |
| Biological source | Homo sapiens More |
| Total number of polymer chains | 3 |
| Total formula weight | 48581.43 |
| Authors | Hall, G.,Cowan, R.,Carr, M.D. (deposition date: 2021-06-22, release date: 2022-06-29, Last modification date: 2024-01-31) |
| Primary citation | Bakrania, P.,Hall, G.,Bouter, Y.,Bouter, C.,Beindorff, N.,Cowan, R.,Davies, S.,Price, J.,Mpamhanga, C.,Love, E.,Matthews, D.,Carr, M.D.,Bayer, T.A. Discovery of a novel pseudo beta-hairpin structure of N-truncated amyloid-beta for use as a vaccine against Alzheimer's disease. Mol Psychiatry, 27:840-848, 2022 Cited by PubMed: 34776512DOI: 10.1038/s41380-021-01385-7 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report
