7OXN
Crystal Structure of TAP01 in complex with cyclised amyloid beta peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | TAP01 family antibody heavy chain | polymer | 219 | 23281.2 | 1 | Homo sapiens | ||
| 2 | B (K) | TAP01 family antibody light chain | polymer | 214 | 23477.9 | 1 | Homo sapiens | ||
| 3 | C (A) | Amyloid-beta precursor protein | polymer | 14 | 1694.8 | 1 | UniProt (P05067) | Homo sapiens | APP,ABPP,APPI,Alzheimer disease amyloid A4 protein homolog,Alzheimer disease amyloid protein,Amyloid precursor protein,Amyloid-beta (A4) precursor protein,Amyloid-beta A4 protein,Cerebral vascular amyloid peptide,CVAP,PreA4,Protease nexin-II,PN-II |
| 4 | D (H) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | E (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | F, G, H (H, K, A) | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence modifications
A: 1 - 14 (UniProt: P05067)
| PDB | External Database | Details |
|---|---|---|
| Smc 3 | Glu 674 | engineered mutation |
| Cys 12 | Val 683 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 48454.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 127.5 | |
| All* | Total formula weight | 48581.4 |
