8C7H
 
 | | Cryo-EM Map of the latTGF-beta 28G11 Fab complex | | 分子名称: | 28G11 Fab heavy chain, 28G11 Fab light chain, Transforming growth factor beta activator LRRC32, ... | | 著者 | Ebenhoch, R, Nar, H. | | 登録日 | 2023-01-16 | | 公開日 | 2023-03-01 | | 最終更新日 | 2023-03-29 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Anti-GARP Antibodies Inhibit Release of TGF-beta by Regulatory T Cells via Different Modes of Action, but Do Not Influence Their Function In Vitro.
Immunohorizons, 7, 2023
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1OAK
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8CE7
 | | Type1 alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein | | 分子名称: | Alpha-synuclein | | 著者 | Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Peak-Chew, S.Y, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M. | | 登録日 | 2023-02-01 | | 公開日 | 2023-03-01 | | 最終更新日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy.
Acta Neuropathol, 145, 2023
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5ZRN
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5ZS9
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5ZSX
 | | Catechol 2,3-dioxygenase with 3-fluorocatechol from Diaphorobacter sp DS2 | | 分子名称: | 1,2-ETHANEDIOL, 3-FLUOROBENZENE-1,2-DIOL, CALCIUM ION, ... | | 著者 | Mishra, K, Arya, C.K, Subramanian, R, Ramanathan, G. | | 登録日 | 2018-04-30 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Catechol 2,3-dioxygenase with 3-fluorocatechol from Diaphorobacter sp DS2.
To Be Published
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8CEB
 | | Type2 alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein | | 分子名称: | Alpha-synuclein | | 著者 | Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Sew, P.C, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M. | | 登録日 | 2023-02-01 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy.
Acta Neuropathol, 145, 2023
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8CO2
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1KT6
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5T51
 | | Structure of the MIND Complex Shows a Regulatory Focus of Yeast Kinetochore Assembly | | 分子名称: | KLLA0E05809p, KLLA0F02343p, SULFATE ION | | 著者 | Dimitrova, Y, Jenni, S, Valverde, R, Khin, Y, Harrison, S.C. | | 登録日 | 2016-08-30 | | 公開日 | 2016-11-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.2007 Å) | | 主引用文献 | Structure of the MIND Complex Defines a Regulatory Focus for Yeast Kinetochore Assembly.
Cell, 167, 2016
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8C3L
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5T59
 | | Structure of the MIND Complex Shows a Regulatory Focus of Yeast Kinetochore Assembly | | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, KLLA0B13629p, KLLA0E05809p, ... | | 著者 | Dimitrova, Y, Jenni, S, Valverde, R, Khin, Y, Harrison, S.C. | | 登録日 | 2016-08-30 | | 公開日 | 2016-11-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.405 Å) | | 主引用文献 | Structure of the MIND Complex Defines a Regulatory Focus for Yeast Kinetochore Assembly.
Cell, 167, 2016
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1ZV5
 | | Crystal structure of the variable domain of the camelid heavy-chain antibody D2-L29 in complex with hen egg white lysozyme | | 分子名称: | Lysozyme C, PHOSPHATE ION, immunoglobulin heavy chain antibody variable domain | | 著者 | De Genst, E, Silence, K, Decanniere, K, Conrath, K, Loris, R, Kinne, J, Muyldermans, S, Wyns, L. | | 登録日 | 2005-06-01 | | 公開日 | 2006-04-04 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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5TRY
 | | Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide PKS2206 | | 分子名称: | (2~{S})-~{N}-[(2~{S})-3-methoxy-1-(naphthalen-1-ylmethylamino)-1-oxidanylidene-propan-2-yl]-4-oxidanylidene-2-(3-phenylpropanoylamino)-4-piperidin-1-yl-butanamide, Proteasome subunit alpha, Proteasome subunit beta | | 著者 | Hsu, H.-C, Fan, H, Singh, P.K, Wang, R, Sukenick, G, Nathan, C, Lin, G, Li, H. | | 登録日 | 2016-10-27 | | 公開日 | 2017-01-11 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.000008 Å) | | 主引用文献 | Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome.
Biochemistry, 56, 2017
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8C03
 | | Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy12 in outward-facing conformation | | 分子名称: | 2-[2-[2-(1~{H}-benzimidazol-2-yl)ethylamino]ethyl]-~{N}-[(3-fluoranylpyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide, Solute carrier family 40 member 1 | | 著者 | Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. | | 登録日 | 2022-12-15 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (3.89 Å) | | 主引用文献 | Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
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1KF5
 | | Atomic Resolution Structure of RNase A at pH 7.1 | | 分子名称: | pancreatic ribonuclease | | 著者 | Berisio, R, Sica, F, Lamzin, V.S, Wilson, K.S, Zagari, A, Mazzarella, L. | | 登録日 | 2001-11-19 | | 公開日 | 2001-12-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Atomic resolution structures of ribonuclease A at six pH values.
Acta Crystallogr.,Sect.D, 58, 2002
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1KI4
 | | CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE I COMPLEXED WITH 5-BROMOTHIENYLDEOXYURIDINE | | 分子名称: | 5-BROMOTHIENYLDEOXYURIDINE, SULFATE ION, THYMIDINE KINASE | | 著者 | Champness, J.N, Bennett, M.S, Wien, F, Visse, R, Summers, W.C, Sanderson, M.R. | | 登録日 | 1998-05-18 | | 公開日 | 1998-12-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands.
Proteins, 32, 1998
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8BZY
 | | Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy3 in occluded conformation | | 分子名称: | 2-[2-[2-(1~{H}-benzimidazol-2-yl)ethylamino]ethyl]-~{N}-[(3-fluoranylpyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide, DIUNDECYL PHOSPHATIDYL CHOLINE, Solute carrier family 40 member 1, ... | | 著者 | Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. | | 登録日 | 2022-12-15 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-05-24 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
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8C02
 | | Structure of SLC40/ferroportin in complex with synthetic nanobody Sy3 in occluded conformation | | 分子名称: | Solute carrier family 40 member 1, Sybody3 | | 著者 | Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. | | 登録日 | 2022-12-15 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-03-29 | | 実験手法 | ELECTRON MICROSCOPY (4.09 Å) | | 主引用文献 | Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
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5WG5
 | | Human GRK2 in complex with Gbetagamma subunits and CCG224061 | | 分子名称: | 5-{[(3S,4R)-4-(4-fluorophenyl)piperidin-3-yl]methoxy}-2H-indazole, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Bouley, R, Tesmer, J.J.G. | | 登録日 | 2017-07-13 | | 公開日 | 2017-12-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein-Coupled Receptor Kinase 2 Inhibitors.
Mol. Pharmacol., 92, 2017
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5WCG
 | | SET and MYND Domain Containing protein 2 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIMETHYL SULFOXIDE, N-lysine methyltransferase SMYD2, ... | | 著者 | Dong, A, Zeng, H, Walker, J.R, Hutch, A, Seitova, A, Tatlock, J, Kumpf, R, Owen, A, Taylor, A, Casimiro-Garcia, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC) | | 登録日 | 2017-06-30 | | 公開日 | 2017-08-02 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | The crystal structure of SMYD2 in complex with compound MTF003
to be published
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8C9C
 | | Cryo-EM captures early ribosome assembly in action | | 分子名称: | 23S rRNA, 50S ribosomal protein L22, 50S ribosomal protein L24, ... | | 著者 | Nikolay, R, Qin, B, Lauer, S. | | 登録日 | 2023-01-21 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (6.62 Å) | | 主引用文献 | Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
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8C91
 | | Cryo-EM captures early ribosome assembly in action | | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Lauer, S, Nikolay, R, Qin, B. | | 登録日 | 2023-01-21 | | 公開日 | 2023-04-05 | | 実験手法 | ELECTRON MICROSCOPY (4.19 Å) | | 主引用文献 | Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
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8C93
 | | Cryo-EM captures early ribosome assembly in action | | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | 著者 | Lauer, S, Nikolay, R, Qin, B. | | 登録日 | 2023-01-21 | | 公開日 | 2023-04-05 | | 実験手法 | ELECTRON MICROSCOPY (4.17 Å) | | 主引用文献 | Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
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8C99
 | | Cryo-EM captures early ribosome assembly in action | | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L15, ... | | 著者 | Nikolay, R, Qin, B, Lauer, S. | | 登録日 | 2023-01-21 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | | 主引用文献 | Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
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