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PDB: 27201 件

7RY1
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human Hsp90_MC domain structure
分子名称: Heat shock protein HSP 90-alpha, N-[2-(1-MALEIMIDYL)ETHYL]-7-DIETHYLAMINOCOUMARIN-3-CARBOXAMIDE
著者Peng, S, Deng, J, Matts, R.
登録日2021-08-24
公開日2022-05-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.523 Å)
主引用文献Crystal structure of the middle and C-terminal domains of Hsp90 alpha labeled with a coumarin derivative reveals a potential allosteric binding site as a drug target.
Acta Crystallogr D Struct Biol, 78, 2022
5SNP
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PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z381729066
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, N-(propan-2-yl)-1H-pyrazole-3-carboxamide, ...
著者Brenk, R, Georgiou, C.
登録日2022-05-30
公開日2023-12-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献PanDDA analysis group deposition
Chemrxiv, 2023
5SN8
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PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z375990520
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, PHOSPHATE ION, ...
著者Brenk, R, Georgiou, C.
登録日2022-05-30
公開日2023-12-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献PanDDA analysis group deposition
Chemrxiv, 2023
5SO4
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PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with JKH93A
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, PHOSPHATE ION, ...
著者Brenk, R, Georgiou, C.
登録日2022-05-30
公開日2023-12-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献PanDDA analysis group deposition
Chemrxiv, 2023
5SND
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PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z1217960891
分子名称: (3S)-3-(3-fluorophenoxy)-1-methylpyrrolidin-2-one, 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ...
著者Brenk, R, Georgiou, C.
登録日2022-05-30
公開日2023-12-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献PanDDA analysis group deposition
Chemrxiv, 2023
5SNQ
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PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z1891773476
分子名称: 1-[(2S)-2,3-dihydro-1,4-benzodioxin-2-yl]-N-methylmethanamine, 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ...
著者Brenk, R, Georgiou, C.
登録日2022-05-30
公開日2023-12-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献PanDDA analysis group deposition
Chemrxiv, 2023
5SNS
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PanDDA analysis group deposition -- Crystal Structure of Pseudomonas Aeruginosa FabF-C164Q mutant protein in complex with Z1354416068
分子名称: 1-(5-amino-1,3-dihydro-2H-isoindol-2-yl)ethan-1-one, 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, ...
著者Brenk, R, Georgiou, C.
登録日2022-05-30
公開日2023-12-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献PanDDA analysis group deposition
Chemrxiv, 2023
5Y78
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Crystal structure of the triose-phosphate/phosphate translocator in complex with inorganic phosphate
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PHOSPHATE ION, Putative hexose phosphate translocator
著者Lee, Y, Nishizawa, T, Takemoto, M, Kumazaki, K, Yamashita, K, Hirata, K, Minoda, A, Nagatoishi, S, Tsumoto, K, Ishitani, R, Nureki, O.
登録日2017-08-16
公開日2017-10-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity
Nat Plants, 3, 2017
5T9R
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Structure of rabbit RyR1 (Ca2+-only dataset, class 3)
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ...
著者Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J.
登録日2016-09-09
公開日2016-10-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Structural Basis for Gating and Activation of RyR1.
Cell, 167, 2016
5TB0
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Structure of rabbit RyR1 (EGTA-only dataset, all particles)
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION
著者Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J.
登録日2016-09-10
公開日2016-10-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural Basis for Gating and Activation of RyR1.
Cell, 167, 2016
8A29
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Apo 1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa
分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, CALCIUM ION, CHLORIDE ION, ...
著者Hamid, R, Adam, S, Lacour, A, Monjas, L, Hirsch, A.
登録日2022-06-02
公開日2023-06-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding.
J.Biol.Chem., 299, 2023
5Y8P
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Mycobacterium tuberculosis 3-Hydroxyisobutyrate dehydrogenase (MtHIBADH) + 3-Hydroxy propionate (3-HP)
分子名称: (2~{S})-2-methylpentanedioic acid, 3-HYDROXY-PROPANOIC ACID, ACRYLIC ACID, ...
著者Srikalaivani, R, Singh, A, Surolia, A, Vijayan, M.
登録日2017-08-21
公開日2018-07-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure, interactions and action ofMycobacterium tuberculosis3-hydroxyisobutyric acid dehydrogenase.
Biochem. J., 475, 2018
5XXX
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GMPCPP-microtubule complexed with nucleotide-free KIF5C
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
著者Morikawa, M, Shigematsu, H, Nitta, R, Hirokawa, N.
登録日2017-07-05
公開日2018-10-10
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (6.43 Å)
主引用文献Kinesin-binding-triggered conformation switching of microtubules contributes to polarized transport
J. Cell Biol., 217, 2018
5XZC
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Cryo-EM structure of p300-p53 protein complex
分子名称: Cellular tumor antigen p53, Histone acetyltransferase p300
著者Ghosh, R, Roy, S, Sengupta, J.
登録日2017-07-12
公開日2019-01-23
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (10.7 Å)
主引用文献Tumor suppressor p53-mediated structural reorganization of the transcriptional coactivator p300.
Biochemistry, 2019
8A36
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Crystal structure of PpSB1-LOV-K117E mutant (dark state), monoclinic form
分子名称: FLAVIN MONONUCLEOTIDE, Sensory box protein
著者Batra-Safferling, R, Granzin, J.
登録日2022-06-07
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of PpSB1-LOV-K117E mutant (dark state), monoclinic form
To Be Published
7SEK
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BU of 7sek by Molmil
Solution structure of the zinc finger domain of murine MetAP1, complexed with ZNG N-terminal peptide
分子名称: COBW domain-containing protein 1,Methionine aminopeptidase 1 fusion, ZINC ION
著者Edmonds, K.A, Jordan, M.R, Thalluri, K, Wu, H, Di Marchi, R, Giedroc, D.P.
登録日2021-09-30
公開日2022-06-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis.
Cell, 185, 2022
7ZTH
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Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the open conformation
分子名称: DNA (48-MER), PLP-dependent aminotransferase family protein
著者Freda, I, Montemiglio, L.C, Tramonti, A, Contestabile, R, Vallone, B, Exertier, C, Savino, C, Chaves Sanjuan, A, Bolognesi, M.
登録日2022-05-10
公開日2023-07-05
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR.
Nucleic Acids Res., 51, 2023
8A39
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Crystal Structure of PaaX from Escherichia coli W
分子名称: DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive, GLYCEROL, ...
著者Molina, R, Alba-Perez, A, Hermoso, J.A.
登録日2022-06-07
公開日2023-07-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural characterization of PaaX, the main repressor of the phenylacetate degradation pathway in Escherichia coli W: A novel fold of transcription regulator proteins.
Int.J.Biol.Macromol., 254, 2024
5TAS
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BU of 5tas by Molmil
Structure of rabbit RyR1 (Caffeine/ATP/EGTA dataset, class 1)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J.
登録日2016-09-10
公開日2016-10-12
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Structural Basis for Gating and Activation of RyR1.
Cell, 167, 2016
5TB8
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Precatalytic ternary complex of Human DNA Polymerase Beta in closed conformation With Gapped DNA substrate incoming (-)3TC-TP and Mn2+.
分子名称: 10- MER PRIMER, 16- MER TEMPLATE, 5-MER PHOSPHORYLATED DOWNSTREAM PRIME, ...
著者Vyas, R, Suo, Z.
登録日2016-09-11
公開日2017-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Insights into the Post-Chemistry Steps of Nucleotide Incorporation Catalyzed by a DNA Polymerase.
J. Am. Chem. Soc., 139, 2017
8A4D
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1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa with a thiamine analog inhibitor
分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, 2-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]phenyl}ethanol, CALCIUM ION, ...
著者Hamid, R, Hirsch, A.
登録日2022-06-10
公開日2023-07-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding.
J.Biol.Chem., 299, 2023
8A45
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Structural analysis of 1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa with 2-acetyl thiamine diphosphate
分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, 2-ACETYL-THIAMINE DIPHOSPHATE, CALCIUM ION, ...
著者Hamid, R, Hirsch, A.
登録日2022-06-10
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding.
J.Biol.Chem., 299, 2023
7ZN5
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Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the closed conformation, C2 symmetry.
分子名称: DNA (48-MER), PLP-dependent aminotransferase family protein
著者Freda, I, Montemiglio, L.C, Tramonti, A, Contestabile, R, Vallone, B, Exertier, C, Savino, C, Chaves Sanjuan, A, Bolognesi, M.
登録日2022-04-20
公開日2023-07-05
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR.
Nucleic Acids Res., 51, 2023
8A33
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Crystal structure of PpSB1-LOV-K117E mutant (light state)
分子名称: Flavin mononucleotide (semi-quinone intermediate), Sensory box protein
著者Batra-Safferling, R, Granzin, J, Krauss, U.
登録日2022-06-07
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Crystal structure of PpSB1-LOV-K117E mutant (light state)
To Be Published
7ZLA
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BU of 7zla by Molmil
Cryo-EM structure of holo-PdxR from Bacillus clausii bound to its target DNA in the half-closed conformation
分子名称: DNA (48-MER), PLP-dependent aminotransferase family protein
著者Freda, I, Montemiglio, L.C, Tramonti, A, Contestabile, R, Vallone, B, Savino, C, Exertier, C, Bolognesi, M, Chaves Sanjuan, A.
登録日2022-04-14
公開日2023-07-05
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (3.99 Å)
主引用文献Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR.
Nucleic Acids Res., 51, 2023

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件を2024-07-17に公開中

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