8RBO
 
 | | Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase contracted clamp conformation | | 分子名称: | DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit Rpo12, ... | | 著者 | Tarau, D.M, Reichelt, R, Heiss, F.B, Pilsl, M, Hausner, W, Engel, C, Grohmann, D. | | 登録日 | 2023-12-04 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment.
Nucleic Acids Res., 52, 2024
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8SD6
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8SJS
 | | [3T18] Self-assembling right-handed tensegrity triangle with 18 interjunction base pairs and P63 symmetry | | 分子名称: | DNA (5'-D(*CP*AP*GP*AP*GP*CP*CP*TP*GP*AP*CP*AP*TP*AP*CP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*CP*TP*GP*TP*GP*GP*CP*TP*C)-3'), DNA (5'-D(P*TP*CP*GP*TP*GP*GP*AP*CP*AP*GP*CP*G)-3'), ... | | 著者 | Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P. | | 登録日 | 2023-04-18 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (6.31 Å) | | 主引用文献 | Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8SL5
 | | [2T13] Self-assembling left-handed two-turn tensegrity triangle with 13 interjunction base pairs and R3 symmetry | | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*CP*TP*GP*AP*CP*TP*AP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*TP*GP*GP*C)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*AP*CP*A)-3'), ... | | 著者 | Vecchioni, S, Janowski, J, Sha, R, Ohayon, Y.P. | | 登録日 | 2023-04-21 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (6.55 Å) | | 主引用文献 | Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8SD9
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8SAG
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8SAF
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8S03
 | | NMR solution structure of the CysD2 domain of MUC2 | | 分子名称: | CALCIUM ION, Mucin-2 | | 著者 | Recktenwald, C, Karlsson, B.G, Garcia-Bonnete, M.-J, Katona, G, Jensen, M, Lymer, R, Baeckstroem, M, Johansson, M.E.V, Hansson, G.C, Trillo-Muyo, S. | | 登録日 | 2024-02-13 | | 公開日 | 2024-04-17 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structure of the second CysD domain of MUC2 and role in mucin organization by transglutaminase-based cross-linking.
Cell Rep, 43, 2024
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8SFM
 | | Crystal structure of the engineered SsoPox variant IVB10 in alternate state | | 分子名称: | 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ... | | 著者 | Jacquet, P, Billot, R, Shimon, A, Hoekstra, N, Bergonzi, C, Jenks, A, Daude, D, Elias, M.H. | | 登録日 | 2023-04-11 | | 公開日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Changes in Active Site Loops Conformation Relates to a Transition from Lactonase to Phosphotriesterase
To Be Published
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8SFB
 | | Crystal structure of the engineered SsoPox variant IVA4 | | 分子名称: | Aryldialkylphosphatase, COBALT (II) ION, FE (III) ION, ... | | 著者 | Jacquet, P, Billot, R, Shimon, A, Hoekstra, N, Bergonzi, C, Jenks, A, Daude, D, Elias, M.H. | | 登録日 | 2023-04-10 | | 公開日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Changes in Active Site Loops Conformation Relates to a Transition from Lactonase to Phosphotriesterase
To Be Published
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8SJT
 | | [3T14+10] Self-assembling left-handed tensegrity triangle with 14 interjunction base pairs and a 10 bp linker with R3 symmetry | | 分子名称: | DNA (5'-D(*AP*CP*CP*TP*CP*CP*TP*GP*AP*GP*GP*TP*CP*GP*AP*GP*C)-3'), DNA (5'-D(*GP*AP*CP*TP*CP*TP*GP*CP*TP*A)-3'), DNA (5'-D(*GP*TP*TP*AP*GP*CP*AP*GP*AP*G)-3'), ... | | 著者 | Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P. | | 登録日 | 2023-04-18 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (9.38 Å) | | 主引用文献 | Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8SJV
 | | [4T24] Self-assembling left-handed tensegrity triangle with 24 interjunction base pairs and R3 symmetry | | 分子名称: | DNA (5'-D(P*CP*TP*TP*GP*TP*AP*GP*TP*CP*TP*CP*AP*CP*CP*AP*CP*TP*GP*TP*GP*AP*TP*GP*T)-3'), DNA (5'-D(P*GP*AP*AP*CP*AP*CP*TP*CP*CP*TP*GP*AP*GP*AP*CP*TP*AP*CP*AP*A)-3'), DNA (5'-D(P*GP*AP*CP*AP*TP*CP*AP*CP*AP*GP*TP*GP*GP*AP*CP*TP*AP*CP*AP*AP*G)-3'), ... | | 著者 | Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P. | | 登録日 | 2023-04-18 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (8.59 Å) | | 主引用文献 | Engineering tertiary chirality in helical biopolymers.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8SF1
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8SD8
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8RUU
 | | Fabs derived from bimekizumab in complex with IL-17F | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoblobulin heavy chain, Immunoblobulin light chain, ... | | 著者 | Adams, R, Lawson, A.D.G. | | 登録日 | 2024-01-31 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Crystal Structure of Bimekizumab Fab Fragment in Complex with IL-17F Provides Molecular Basis for Dual IL-17A and IL-17F Inhibition.
J Invest Dermatol., 2024
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8SH4
 | | Crystal structure of the tRNA (m1G37) methyltransferase apoenzyme from Anaplasma phagocytophilum | | 分子名称: | GLYCEROL, tRNA (guanine-N(1)-)-methyltransferase | | 著者 | Jannotta, C, Edele, D, Levanti, D, Carson, M, Prucha, G, Caesar, J, Picchiello, C, Collins, K, Garland, E, Handley-Pendleton, J, Hernandez, V, Leffler, S, Williams, D, Stojanoff, V, Perez, A, Halloran, J, Bolen, R. | | 登録日 | 2023-04-13 | | 公開日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of the m1G37 tRNA methyltransferase apoenzyme from Anaplasma phagocytophilum
To Be Published
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8SIH
 | | Crystal Structure of PRMT4 with Compound YD1-289 | | 分子名称: | 5'-{[2-(benzylcarbamamido)ethyl][3-(N'-cyclopentylcarbamimidamido)propyl]amino}-5'-deoxyadenosine, CALCIUM ION, Histone-arginine methyltransferase CARM1 | | 著者 | Song, X, Dong, A, Deng, Y, Huang, R, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2023-04-16 | | 公開日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal Structure of PRMT4 with Compound YD1-289
To be published
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8RHR
 | | E.coli Peptide Deformylase with bound inhibitor BB4 | | 分子名称: | 2-(5-bromo-1H-indol-3-yl)-N-hydroxyacetamide, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Kirschner, H, Stoll, R, Hofmann, E. | | 登録日 | 2023-12-16 | | 公開日 | 2024-04-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Toward More Selective Antibiotic Inhibitors: A Structural View of the Complexed Binding Pocket of E. coli Peptide Deformylase.
J.Med.Chem., 67, 2024
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8SF2
 | | Crystal structure of the engineered SsoPox variant IG7 | | 分子名称: | Aryldialkylphosphatase, COBALT (II) ION, FE (III) ION, ... | | 著者 | Jacquet, P, Billot, R, Shimon, A, Hoekstra, N, Bergonzi, C, Jenks, A, Daude, D, Elias, M.H. | | 登録日 | 2023-04-10 | | 公開日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Changes in Active Site Loops Conformation Relates to a Transition from Lactonase to Phosphotriesterase
To Be Published
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8SIG
 | | Crystal Structure of PRMT4 with Compound YD1-288 | | 分子名称: | 5'-{(3-aminopropyl)[2-(benzylcarbamamido)ethyl]amino}-5'-deoxyadenosine, Histone-arginine methyltransferase CARM1, SODIUM ION, ... | | 著者 | Song, X, Dong, A, Deng, Y, Huang, R, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | | 登録日 | 2023-04-16 | | 公開日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Crystal Structure of PRMT4 with Compound YD1-288
To be published
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8RTZ
 | | The structure of E. coli penicillin binding protein 3 (PBP3) in complex with a bicyclic peptide inhibitor | | 分子名称: | 1,1',1''-(1,3,5-triazinane-1,3,5-triyl)tripropan-1-one, Bicyclic peptide inhibitor, Peptidoglycan D,D-transpeptidase FtsI | | 著者 | Newman, H, Rowland, C.E, Dods, R, Lewis, N, Stanway, S.J, Bellini, D, Beswick, P. | | 登録日 | 2024-01-29 | | 公開日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | Discovery and chemical optimisation of a Potent, Bi-cyclic (Bicycle) Antimicrobial Inhibitor of Escherichia coli PBP3
To Be Published
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8SFA
 | | Crystal structure of the engineered SsoPox variant IIIC1 | | 分子名称: | Aryldialkylphosphatase, COBALT (II) ION, FE (III) ION | | 著者 | Jacquet, P, Billot, R, Shimon, A, Hoekstra, N, Bergonzi, C, Jenks, A, Daude, D, Elias, M.H. | | 登録日 | 2023-04-10 | | 公開日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Changes in Active Site Loops Conformation Relates to a Transition from Lactonase to Phosphotriesterase
To Be Published
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8SF9
 | | Crystal structure of the engineered SsoPox variant IG7 - Alternative state | | 分子名称: | Aryldialkylphosphatase, COBALT (II) ION, FE (III) ION | | 著者 | Jacquet, P, Billot, R, Shimon, A, Hoekstra, N, Bergonzi, C, Jenks, A, Daude, D, Elias, M.H. | | 登録日 | 2023-04-10 | | 公開日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Changes in Active Site Loops Conformation Relates to a Transition from Lactonase to Phosphotriesterase
To Be Published
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8SFC
 | | Crystal structure of the engineered SsoPox variant IVA4 in alternate state | | 分子名称: | Aryldialkylphosphatase, COBALT (II) ION, FE (III) ION, ... | | 著者 | Jacquet, P, Billot, R, Shimon, A, Hoekstra, N, Bergonzi, C, Jenks, A, Daude, D, Elias, M.H. | | 登録日 | 2023-04-10 | | 公開日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Changes in Active Site Loops Conformation Relates to a Transition from Lactonase to Phosphotriesterase
To Be Published
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8SFK
 | | Crystal structure of the engineered SsoPox variant IVE2 | | 分子名称: | Aryldialkylphosphatase, COBALT (II) ION, FE (III) ION, ... | | 著者 | Jacquet, P, Billot, R, Shimon, A, Hoekstra, N, Bergonzi, C, Jenks, A, Daude, D, Elias, M.H. | | 登録日 | 2023-04-11 | | 公開日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Changes in Active Site Loops Conformation Relates to a Transition from Lactonase to Phosphotriesterase
To Be Published
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