2XNE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xne by Molmil](/molmil-images/mine/2xne) | Structure of Aurora-A bound to an imidazopyrazine inhibitor | 分子名称: | 3-chloro-N-(4-morpholin-4-ylphenyl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine, SERINE/THREONINE-PROTEIN KINASE 6 | 著者 | Kosmopoulou, M, Bayliss, R. | 登録日 | 2010-08-02 | 公開日 | 2010-09-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-based design of imidazo[1,2-a]pyrazine derivatives as selective inhibitors of Aurora-A kinase in cells. Bioorg. Med. Chem. Lett., 20, 2010
|
|
1MQJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mqj by Molmil](/molmil-images/mine/1mqj) | Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with willardiine at 1.65 angstroms resolution | 分子名称: | 2-AMINO-3-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, ZINC ION, glutamate receptor 2 | 著者 | Jin, R, Banke, T.G, Mayer, M.L, Traynelis, S.F, Gouaux, E. | 登録日 | 2002-09-16 | 公開日 | 2003-08-05 | 最終更新日 | 2017-08-02 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural basis for partial agonist action at ionotropic glutamate receptors Nat.Neurosci., 6, 2003
|
|
2XZ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xz6 by Molmil](/molmil-images/mine/2xz6) | MTSET-modified Y53C mutant of Aplysia AChBP | 分子名称: | 2-(TRIMETHYLAMMONIUM)ETHYL THIOL, SOLUBLE ACETYLCHOLINE RECEPTOR | 著者 | Brams, M, Gay, E.A, Colon Saez, J, Guskov, A, Van Elk, R, Van Der Schors, R.C, Peigneur, S, Tytgat, J, Strelkov, S.V, Smit, A.B, Yakel, J.L, Ulens, C. | 登録日 | 2010-11-23 | 公開日 | 2010-12-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.137 Å) | 主引用文献 | Crystal Structures of a Cysteine-Modified Mutant in Loop D of Acetylcholine Binding Protein J.Biol.Chem., 286, 2011
|
|
1M3A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1m3a by Molmil](/molmil-images/mine/1m3a) | Solution structure of a circular form of the truncated N-terminal SH3 domain from oncogene protein c-Crk. | 分子名称: | Proto-oncogene C-crk | 著者 | Schumann, F.H, Varadan, R, Tayakuniyil, P.P, Hall, J.B, Camarero, J.A, Fushman, D. | 登録日 | 2002-06-27 | 公開日 | 2003-08-05 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Changing protein backbone topology: Structural and dynamic consequences of the backbone cyclization in SH3 domain To be Published
|
|
2Y0R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2y0r by Molmil](/molmil-images/mine/2y0r) | Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2 | 分子名称: | MYOSIN-2 HEAVY CHAIN | 著者 | Preller, M, Bauer, S, Adamek, N, Fujita-Becker, S, Fedorov, R, Geeves, M.A, Manstein, D.J. | 登録日 | 2010-12-07 | 公開日 | 2011-07-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V. J.Biol.Chem., 286, 2011
|
|
2XOZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xoz by Molmil](/molmil-images/mine/2xoz) | C-terminal cysteine rich domain of human CHFR bound to AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, E3 UBIQUITIN-PROTEIN LIGASE CHFR, ZINC ION | 著者 | Oberoi, J, Bayliss, R. | 登録日 | 2010-08-24 | 公開日 | 2010-09-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.374 Å) | 主引用文献 | Structural Basis of Poly(Adp-Ribose) Recognition by the Multizinc Binding Domain of Checkpoint with Forkhead-Associated and Ring Domains (Chfr). J.Biol.Chem., 285, 2010
|
|
4O43
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o43 by Molmil](/molmil-images/mine/4o43) | DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities | 分子名称: | (5~{E})-3-[(2~{R})-butan-2-yl]-5-[(4-hydroxyphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, Exonuclease, putative, ... | 著者 | Shibata, A, Moiani, D, Arvai, A.S, Perry, J, Harding, S.M, Genois, M, Maity, R, Rossum-Fikkert, S, Kertokalio, A, Romoli, F, Ismail, A, Ismalaj, E, Petricci, E, Neale, M.J, Bristow, R.G, Masson, J, Wyman, C, Jeggo, P.A, Tainer, J.A. | 登録日 | 2013-12-18 | 公開日 | 2014-01-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities. Mol.Cell, 53, 2014
|
|
1MJB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mjb by Molmil](/molmil-images/mine/1mjb) | Crystal structure of yeast Esa1 histone acetyltransferase E338Q mutant complexed with acetyl coenzyme A | 分子名称: | ACETYL COENZYME *A, Esa1 protein | 著者 | Yan, Y, Harper, S, Speicher, D, Marmorstein, R. | 登録日 | 2002-08-27 | 公開日 | 2002-10-30 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate. Nat.Struct.Biol., 9, 2002
|
|
2XXQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xxq by Molmil](/molmil-images/mine/2xxq) | A widespread family of bacterial cell wall assembly proteins | 分子名称: | (2Z,6Z,10Z,14Z,18Z,22Z,26Z)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl trihydrogen diphosphate, 1,2-ETHANEDIOL, ACETATE ION, ... | 著者 | Marles-Wright, J, Kawai, Y, Emmins, R, Ishikawa, S, Kuwano, M, Heinz, N, Cleverley, R.M, Bui, N.K, Ogasawara, N, Lewis, R.J, Vollmer, W, Daniel, R.A, Errington, J. | 登録日 | 2010-11-11 | 公開日 | 2011-10-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | A Widespread Family of Bacterial Cell Wall Assembly Proteins. Embo J., 30, 2011
|
|
2XLR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xlr by Molmil](/molmil-images/mine/2xlr) | |
2XX6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xx6 by Molmil](/molmil-images/mine/2xx6) | Structure of the Bacillus subtilis prophage dUTPase, YosS | 分子名称: | SPBC2 PROPHAGE-DERIVED DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YOSS | 著者 | Garcia-Nafria, J, Harkiolaki, M, Persson, R, Fogg, M.J, Wilson, K.S. | 登録日 | 2010-11-08 | 公開日 | 2011-02-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | The Structure of Bacillus Subtilis Sp Beta Prophage Dutpase and its Complexes with Two Nucleotides Acta Crystallogr.,Sect.D, 67, 2011
|
|
4O34
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o34 by Molmil](/molmil-images/mine/4o34) | Room temperature macromolecular serial crystallography using synchrotron radiation | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | Stellato, F, Oberthuer, D, Liang, M, Bean, R, Gati, C, Yefanov, O, Barty, A, Burkhardt, A, Fischer, P, Galli, L, Kirian, R.A, Mayer, J, Pannerselvam, S, Yoon, C.H, Chervinskii, F, Speller, E, White, T.A, Betzel, C, Meents, A, Chapman, H.N. | 登録日 | 2013-12-18 | 公開日 | 2014-06-11 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Room-temperature macromolecular serial crystallography using synchrotron radiation. IUCrJ, 1, 2014
|
|
2XNZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xnz by Molmil](/molmil-images/mine/2xnz) | xpt-pbuX C74U Riboswitch from B. subtilis bound to acetoguanamine identified by virtual screening | 分子名称: | 6-METHYL-1,3,5-TRIAZINE-2,4-DIAMINE, ACETATE ION, COBALT HEXAMMINE(III), ... | 著者 | Daldrop, P, Reyes, F.E, Robinson, D.A, Hammond, C.M, Lilley, D.M.J, Batey, R.T, Brenk, R. | 登録日 | 2010-08-06 | 公開日 | 2011-04-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Novel ligands for a purine riboswitch discovered by RNA-ligand docking. Chem. Biol., 18, 2011
|
|
1M1U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1m1u by Molmil](/molmil-images/mine/1m1u) | AN ISOLEUCINE-BASED ALLOSTERIC SWITCH CONTROLS AFFINITY AND SHAPE SHIFTING IN INTEGRIN CD11B A-DOMAIN | 分子名称: | CALCIUM ION, Integrin alpha-M | 著者 | Xiong, J.-P, Li, R, Essafi, M, Stehle, T, Arnaout, M.A. | 登録日 | 2002-06-20 | 公開日 | 2002-08-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | An isoleucine-based allosteric switch controls affinity and shape shifting in integrin CD11b A-domain. J.Biol.Chem., 275, 2000
|
|
4O5G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o5g by Molmil](/molmil-images/mine/4o5g) | DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities | 分子名称: | (5~{E})-5-[(4-aminophenyl)methylidene]-2-azanylidene-1,3-thiazolidin-4-one, Exonuclease, putative, ... | 著者 | Shibata, A, Moiani, D, Arvai, A.S, Perry, J, Harding, S.M, Genois, M, Maity, R, Rossum-Fikkert, S, Kertokalio, A, Romoli, F, Ismail, A, Ismalaj, E, Petricci, E, Neale, M.J, Bristow, R.G, Masson, J, Wyman, C, Jeggo, P.A, Tainer, J.A. | 登録日 | 2013-12-19 | 公開日 | 2014-01-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | DNA Double-Strand Break Repair Pathway Choice Is Directed by Distinct MRE11 Nuclease Activities. Mol.Cell, 53, 2014
|
|
2XSD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xsd by Molmil](/molmil-images/mine/2xsd) | Crystal Structure of the dimeric Oct-6 (Pou3f1) POU domain bound to palindromic MORE DNA | 分子名称: | 1,2-ETHANEDIOL, 5'-D(*AP*TP*GP*CP*AP*TP*GP*AP*GP*GP*AP)-3', 5'-D(*CP*CP*TP*CP*AP*TP*GP*CP*AP*TP*AP)-3', ... | 著者 | Jauch, R, Choo, S.H, Ng, C.K.L, Kolatkar, P.R. | 登録日 | 2010-09-28 | 公開日 | 2010-10-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.049 Å) | 主引用文献 | Crystal Structure of the Dimeric Oct6 (POU3F1) POU Domain Bound to Palindromic More DNA. Proteins, 79, 2011
|
|
2XSX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xsx by Molmil](/molmil-images/mine/2xsx) | Crystal structure of human beta enolase ENOB | 分子名称: | 1,2-ETHANEDIOL, BETA-ENOLASE, MAGNESIUM ION, ... | 著者 | Vollmar, M, Krysztofinska, E, Chaikuad, A, Krojer, T, Cocking, R, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Yue, W.W, Oppermann, U. | 登録日 | 2010-09-30 | 公開日 | 2010-11-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structure of Human Beta Enolase Enob To be Published
|
|
2Y2W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2y2w by Molmil](/molmil-images/mine/2y2w) | Elucidation of the substrate specificity and protein structure of AbfB, a family 51 alpha-L-arabinofuranosidase from Bifidobacterium longum. | 分子名称: | ARABINOFURANOSIDASE | 著者 | Lagaert, S, Schoepe, J, Delcour, J.A, Lavigne, R, Strelkov, S.V, Courtin, C.M, Mikkelsen, N.E, Sandgren, M, Volckaert, G. | 登録日 | 2010-12-16 | 公開日 | 2011-12-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Elucidation of the Substrate Specificity and Protein Structure of Abfb, a Family 51 Alpha-L- Arabinofuranosidase from Bifidobacterium Longum. To be Published
|
|
1M3I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1m3i by Molmil](/molmil-images/mine/1m3i) | Perfringolysin O, new crystal form | 分子名称: | perfringolysin O | 著者 | Rossjohn, J, Parker, M, Polekhina, G, Feil, S, Tweten, R. | 登録日 | 2002-06-28 | 公開日 | 2004-02-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural Snapshots in the Molecular Mechanism of PFO Revealed To be Published
|
|
2XNP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xnp by Molmil](/molmil-images/mine/2xnp) | Structure of Nek2 bound to CCT244858 | 分子名称: | 1,2-ETHANEDIOL, 4-{5-[(1-METHYLPIPERIDIN-4-YL)OXY]-1H-BENZIMIDAZOL-1-YL}-2-{(1R)-1-[2-(TRIFLUOROMETHYL)PHENYL]ETHOXY}BENZAMIDE, CHLORIDE ION, ... | 著者 | Mas-Droux, C, Bayliss, R. | 登録日 | 2010-08-05 | 公開日 | 2011-03-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Benzimidazole Inhibitors Induce a Dfg-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure-Activity Relationship. J.Med.Chem., 54, 2011
|
|
2XOE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xoe by Molmil](/molmil-images/mine/2xoe) | Crystal structure of flavoprotein NrdI from Bacillus anthracis in the semiquinone form | 分子名称: | ACETATE ION, CACODYLATE ION, FLAVIN MONONUCLEOTIDE, ... | 著者 | Johansson, R, Sprenger, J, Torrents, E, Sahlin, M, Sjoberg, B.M, Logan, D.T. | 登録日 | 2010-08-14 | 公開日 | 2010-08-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | High Resolution Crystal Structures of Nrdi in the Oxidised and Reduced States: An Unusual Flavodoxin FEBS J., 277, 2010
|
|
2XZ4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xz4 by Molmil](/molmil-images/mine/2xz4) | Crystal structure of the LFZ ectodomain of the peptidoglycan recognition protein LF | 分子名称: | 1,2-ETHANEDIOL, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, COPPER (II) ION, ... | 著者 | Basbous, N, Coste, F, Leone, P, Vincentelli, R, Royet, J, Kellenberger, C, Roussel, A. | 登録日 | 2010-11-23 | 公開日 | 2011-04-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | The Drosophila Peptidoglycan-Recognition Protein Lf Interacts with Peptidoglycan-Recognition Protein Lc to Downregulate the Imd Pathway. Embo Rep., 12, 2011
|
|
2XPC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xpc by Molmil](/molmil-images/mine/2xpc) | Second-generation sulfonamide inhibitors of MurD: Activity optimisation with conformationally rigid analogues of D-glutamic acid | 分子名称: | (1R,3R,4S)-4-[({6-[(4-CYANO-2-FLUOROBENZYL)OXY]NAPHTHALEN-2-YL}SULFONYL)AMINO]CYCLOHEXANE-1,3-DICARBOXYLIC ACID, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Sosic, I, Barreteau, H, Simcic, M, Sink, R, Cesar, J, Golic-Grdadolnik, S, Contreras-Martel, C, Dessen, A, Amoroso, A, Joris, B, Blanot, D, Gobec, S. | 登録日 | 2010-08-26 | 公開日 | 2011-05-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Second-Generation Sulfonamide Inhibitors of D- Glutamic Acid-Adding Enzyme: Activity Optimisation with Conformationally Rigid Analogues of D- Glutamic Acid. Eur.J.Med.Chem, 46, 2011
|
|
2Y1T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2y1t by Molmil](/molmil-images/mine/2y1t) | Bacillus subtilis prophage dUTPase in complex with dUDP | 分子名称: | DEOXYURIDINE-5'-DIPHOSPHATE, SPBC2 PROPHAGE-DERIVED DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YOSS | 著者 | Garcia-Nafria, J, Harkiolaki, M, Persson, R, Fogg, M.J, Wilson, K.S. | 登録日 | 2010-12-10 | 公開日 | 2011-02-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | The Structure of Bacillus Subtilis Sp Beta Prophage Dutpase and its Complexes with Two Nucleotides Acta Crystallogr.,Sect.D, 67, 2011
|
|
2XC1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xc1 by Molmil](/molmil-images/mine/2xc1) | Full-length Tailspike Protein Mutant Y108W of Bacteriophage P22 | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, BIFUNCTIONAL TAIL PROTEIN, CALCIUM ION, ... | 著者 | Mueller, J.J, Seul, A, Seckler, R, Heinemann, U. | 登録日 | 2010-04-15 | 公開日 | 2011-05-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Bacteriophage P22 Tailspike: Structure of the Complete Protein and Function of the Interdomain Linker Acta Crystallogr.,Sect.D, 70, 2014
|
|