1VQ2
 
 | | CRYSTAL STRUCTURE OF T4-BACTERIOPHAGE DEOXYCYTIDYLATE DEAMINASE, MUTANT R115E | | 分子名称: | 3,4-DIHYDRO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, DEOXYCYTIDYLATE DEAMINASE, ZINC ION | | 著者 | Almog, R, Maley, F, Maley, G.F, Maccoll, R, Van Roey, P. | | 登録日 | 2004-12-15 | | 公開日 | 2004-12-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Three-Dimensional Structure of the R115E Mutant of T4-Bacteriophage 2'-Deoxycytidylate Deaminase
Biochemistry, 43, 2004
|
|
3IK4
 | | CRYSTAL STRUCTURE OF mandelate racemase/muconate lactonizing protein from Herpetosiphon aurantiacus | | 分子名称: | GLYCEROL, Mandelate racemase/muconate lactonizing protein, POTASSIUM ION | | 著者 | Patskovsky, Y, Toro, R, Dickey, M, Iizuka, M, Sauder, J.M, Gerlt, J.A, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2009-08-05 | | 公開日 | 2009-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily.
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
7N5S
 | | ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 6) | | 分子名称: | DNA Strand I, DNA Strand II, ZINC ION, ... | | 著者 | Horton, J.R, Ren, R, Cheng, X. | | 登録日 | 2021-06-06 | | 公開日 | 2021-08-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | Structural basis for human ZBTB7A action at the fetal globin promoter.
Cell Rep, 36, 2021
|
|
6XXW
 | | Structure of beta-D-Glucuronidase for Dictyoglomus thermophilum. | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-glucuronidase, ... | | 著者 | Lafite, P, Daniellou, R. | | 登録日 | 2020-01-28 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | | 主引用文献 | Thioglycoligation of aromatic thiols using a natural glucuronide donor.
Org.Biomol.Chem., 18, 2020
|
|
7N5T
 | | ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 5) | | 分子名称: | DNA Strand I, DNA Strand II, ZINC ION, ... | | 著者 | Horton, J.R, Ren, R, Cheng, X. | | 登録日 | 2021-06-06 | | 公開日 | 2021-08-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural basis for human ZBTB7A action at the fetal globin promoter.
Cell Rep, 36, 2021
|
|
5HKV
 | | The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lincomycin | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 23s ribosomal RNA, 50S ribosomal protein L13, ... | | 著者 | Yonath, A, Matzov, D, Eyal, Z, Ben Hamou, R, Zimmerman, E, Rozenberg, H, Bashan, A, Fridman, M. | | 登録日 | 2016-01-14 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.66 Å) | | 主引用文献 | Structural insights of lincosamides targeting the ribosome of Staphylococcus aureus.
Nucleic Acids Res., 45, 2017
|
|
6XXY
 | | Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase in complex with O-isobutenyl oxalylhydroxamate. | | 分子名称: | 2-(2-methylprop-2-enoxyamino)-2-oxidanylidene-ethanoic acid, 3-isopropylmalate dehydrogenase, MAGNESIUM ION, ... | | 著者 | Miggiano, R, Rossi, F, Martignon, S, Rizzi, M. | | 登録日 | 2020-01-28 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Crystal structure of Haemophilus influenzae 3-isopropylmalate dehydrogenase (LeuB) in complex with the inhibitor O-isobutenyl oxalylhydroxamate.
Biochem.Biophys.Res.Commun., 524, 2020
|
|
2YME
 | | Crystal structure of a mutant binding protein (5HTBP-AChBP) in complex with granisetron | | 分子名称: | 1-methyl-N-[(1R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, ... | | 著者 | Kesters, D, Thompson, A.J, Brams, M, Elk, R.v, Spurny, R, Geitmann, M, Villalgordo, J.M, Guskov, A, Danielson, U.H, Lummis, S.C.R, Smit, A.B, Ulens, C. | | 登録日 | 2012-10-09 | | 公開日 | 2012-12-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis of Ligand Recognition in 5-Ht3 Receptors.
Embo Rep., 14, 2013
|
|
7N0L
 | |
7N0K
 | |
3I74
 | |
8IM7
 | | Human gamma-secretase treated with ganglioside GM1 | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhou, R, Yang, G, Shi, Y. | | 登録日 | 2023-03-06 | | 公開日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Preferential Regulation of Gamma-Secretase-Mediated Cleavage of APP by Ganglioside GM1 Reveals a Potential Therapeutic Target for Alzheimer's Disease.
Adv Sci, 10, 2023
|
|
7NA6
 | |
3LYR
 | | Human Early B-cell Factor 1 (EBF1) DNA-binding domain | | 分子名称: | AMMONIUM ION, SULFATE ION, Transcription factor COE1, ... | | 著者 | Siponen, M.I, Wisniewska, M, Arrowsmith, C.H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kraulis, P, Kotenyova, T, Markova, N, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schuler, H, Schutz, P, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Berglund, H, Structural Genomics Consortium (SGC) | | 登録日 | 2010-02-28 | | 公開日 | 2010-03-16 | | 最終更新日 | 2014-10-08 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif.
J.Biol.Chem., 285, 2010
|
|
7NBA
 | | Plasmodium falciparum kinesin-5 motor domain bound to AMPPNP, complexed with 14 protofilament microtubule. | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin motor domain-containing protein,Kinesin motor domain-containing protein, MAGNESIUM ION, ... | | 著者 | Cook, A.D, Roberts, A, Atherton, J, Tewari, R, Topf, M, Moores, C.A. | | 登録日 | 2021-01-25 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition.
J.Biol.Chem., 297, 2021
|
|
7NB8
 | | Plasmodium falciparum kinesin-5 motor domain without nucleotide, complexed with 14 protofilament microtubule. | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Kinesin-5, MAGNESIUM ION, ... | | 著者 | Cook, A.D, Roberts, A, Atherton, J, Tewari, R, Topf, M, Moores, C.A. | | 登録日 | 2021-01-25 | | 公開日 | 2021-10-13 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition.
J.Biol.Chem., 297, 2021
|
|
8BYU
 | | Crystal Structure of HexaBody-CD38 Fab in complex with CD38 | | 分子名称: | 1,2-ETHANEDIOL, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Fab Heavy Chain, ... | | 著者 | Freier, R, Krapp, S, Hibbert, R.G. | | 登録日 | 2022-12-14 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Preclinical anti-tumour activity of HexaBody-CD38, a next-generation CD38 antibody with superior complement-dependent cytotoxic activity.
Ebiomedicine, 93, 2023
|
|
6XM8
 | | Crystal structure of lignostilbene bound to Co-LSD4 from Sphingobium sp. strain SYK-6 | | 分子名称: | COBALT (II) ION, DIMETHYL SULFOXIDE, Dioxygenase, ... | | 著者 | Kuatsjah, E, Chan, A.C, Katahira, R, Beckham, G.T, Murphy, M.E, Eltis, L.D. | | 登録日 | 2020-06-29 | | 公開日 | 2021-05-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural and functional analysis of lignostilbene dioxygenases from Sphingobium sp. SYK-6.
J.Biol.Chem., 296, 2021
|
|
6XMA
 | | Crystal structure of iron-bound LSD4 from Sphingobium sp. strain SYK-6 | | 分子名称: | Dioxygenase, FE (III) ION, SULFATE ION | | 著者 | Kuatsjah, E, Chan, A.C, Katahira, R, Beckham, G.T, Murphy, M.E, Eltis, L.D. | | 登録日 | 2020-06-29 | | 公開日 | 2021-05-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structural and functional analysis of lignostilbene dioxygenases from Sphingobium sp. SYK-6.
J.Biol.Chem., 296, 2021
|
|
5HOT
 | | Structural Basis for Inhibitor-Induced Aggregation of HIV-1 Integrase | | 分子名称: | (2S)-tert-butoxy[4-(8-fluoro-5-methyl-3,4-dihydro-2H-chromen-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinolin-3-yl]ethanoic acid, Integrase | | 著者 | Gupta, K, Turkki, V, Sherrill-Mix, S, Hwang, Y, Eilers, G, Taylor, L, McDanal, C, Wang, P, Temelkoff, D, Nolte, R, Velthuisen, E, Jeffrey, J, Van Duyne, G.D, Bushman, F.D. | | 登録日 | 2016-01-19 | | 公開日 | 2016-12-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (4.4 Å) | | 主引用文献 | Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase.
PLoS Biol., 14, 2016
|
|
6XM9
 | | Crystal structure of vanillin bound to Co-LSD4 from Sphingobium sp. strain SYK-6 | | 分子名称: | 4-hydroxy-3-methoxybenzaldehyde, ACETATE ION, COBALT (II) ION, ... | | 著者 | Kuatsjah, E, Chan, A.C, Katahira, R, Beckham, G.T, Murphy, M.E, Eltis, L.D. | | 登録日 | 2020-06-29 | | 公開日 | 2021-05-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.651 Å) | | 主引用文献 | Structural and functional analysis of lignostilbene dioxygenases from Sphingobium sp. SYK-6.
J.Biol.Chem., 296, 2021
|
|
6XM7
 | | Crystal structure of DCA-S bound to Co-LSD4 from Sphingobium sp. strain SYK-6 | | 分子名称: | (2E)-3-{4-hydroxy-3-[(E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-5-methoxyphenyl}prop-2-enoic acid, COBALT (II) ION, DIMETHYL SULFOXIDE, ... | | 著者 | Kuatsjah, E, Chan, A.C, Katahira, R, Beckham, G.T, Murphy, M.E, Eltis, L.D. | | 登録日 | 2020-06-29 | | 公開日 | 2021-05-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structural and functional analysis of lignostilbene dioxygenases from Sphingobium sp. SYK-6.
J.Biol.Chem., 296, 2021
|
|
6XM6
 | | Crystal structure of cobalt-bound LSD4 from Sphingobium sp. strain SYK-6 | | 分子名称: | COBALT (II) ION, Dioxygenase | | 著者 | Kuatsjah, E, Chan, A.C, Katahira, R, Beckham, G.T, Murphy, M.E, Eltis, L.D. | | 登録日 | 2020-06-29 | | 公開日 | 2021-05-12 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structural and functional analysis of lignostilbene dioxygenases from Sphingobium sp. SYK-6.
J.Biol.Chem., 296, 2021
|
|
8IU6
 | | Crystal structure of peptidyl-tRNA hydrolase mutant from Enterococcus faecium | | 分子名称: | GLYCEROL, Peptidyl-tRNA hydrolase | | 著者 | Pandey, R, Tripathi, S, Lanka, A.K, Zohib, M, Pal, R.K, Arora, A. | | 登録日 | 2023-03-23 | | 公開日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of peptidyl-tRNA hydrolase mutant from Enterococcus faecium
To Be Published
|
|
3ILZ
 | | Structure of TR-alfa bound to selective thyromimetic GC-1 in P212121 space group | | 分子名称: | Thyroid hormone receptor, alpha isoform 1 variant, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid | | 著者 | Aparicio, R, Polikarpov, L, Bleicher, L. | | 登録日 | 2009-08-07 | | 公開日 | 2010-04-28 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.
Bmc Struct.Biol., 8, 2008
|
|
