5AMG
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7KCB
| Symmetry in Yeast Alcohol Dehydrogenase 1 -Closed Form with NAD+ and Trifluoroethanol | Descriptor: | ADH1 isoform 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRIFLUOROETHANOL, ... | Authors: | Subramanian, R, Chang, L, Li, Z, Plapp, B.V. | Deposit date: | 2020-10-05 | Release date: | 2021-03-31 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Cryo-Electron Microscopy Structures of Yeast Alcohol Dehydrogenase. Biochemistry, 60, 2021
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7KCQ
| Symmetry in Yeast Alcohol Dehydrogenase 1 -Open Form of Apoenzyme | Descriptor: | Alcohol dehydrogenase, ZINC ION | Authors: | Subramanian, R, Chang, L, Li, Z, Plapp, B.V. | Deposit date: | 2020-10-07 | Release date: | 2021-03-31 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-Electron Microscopy Structures of Yeast Alcohol Dehydrogenase. Biochemistry, 60, 2021
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5L3L
| D11 bound IGF-II | Descriptor: | Insulin-like growth factor II | Authors: | Hexnerova, R. | Deposit date: | 2016-05-23 | Release date: | 2016-08-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
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5L3M
| D11 bound [S39_PQ]-IGF-II | Descriptor: | Insulin-like growth factor II | Authors: | Hexnerova, R. | Deposit date: | 2016-05-23 | Release date: | 2016-08-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
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4Q24
| Crystal structure of Cyclo(L-leucyl-L-phenylalanyl) synthase | Descriptor: | Cyclo(L-leucyl-L-phenylalanyl) synthase, PHENYLMETHYL N-[(2S)-4-CHLORO-3-OXO-1-PHENYL-BUTAN-2-YL]CARBAMATE | Authors: | Moutiez, M, Schmitt, E, Seguin, J, Thai, R, Favry, E, Mechulam, Y, Gondry, M. | Deposit date: | 2014-04-07 | Release date: | 2014-10-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Unravelling the mechanism of non-ribosomal peptide synthesis by cyclodipeptide synthases. Nat Commun, 5, 2014
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7KC2
| Symmetry in Yeast Alcohol Dehydrogenase 1 -Closed Form with NADH | Descriptor: | Alcohol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION | Authors: | Subramanian, R, Chang, L, Li, Z, Plapp, B.V. | Deposit date: | 2020-10-04 | Release date: | 2021-03-31 | Method: | ELECTRON MICROSCOPY (2.67 Å) | Cite: | Cryo-Electron Microscopy Structures of Yeast Alcohol Dehydrogenase. Biochemistry, 60, 2021
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5L3N
| D11 bound [N29, S39_PQ]-IGF-II | Descriptor: | Insulin-like growth factor II | Authors: | Hexnerova, R. | Deposit date: | 2016-05-23 | Release date: | 2016-08-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
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3R7Y
| CDK2 in complex with inhibitor KVR-2-88 | Descriptor: | 1,2-ETHANEDIOL, 2-{[(2-aminopyrimidin-5-yl)methyl]amino}-4-(morpholin-4-yl)-5-nitrobenzamide, Cyclin-dependent kinase 2 | Authors: | Betzi, S, Alam, R, Han, H, Becker, A, Schonbrunn, E. | Deposit date: | 2011-03-23 | Release date: | 2012-08-08 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-guided optimization of novel CDK2 inhibitors discovered by high-throughput screening To be Published
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5LAO
| S-nitrosylated 3D NMR structure of the cytoplasmic rhodanese domain of the inner membrane protein YgaP from Escherichia coli | Descriptor: | Inner membrane protein YgaP | Authors: | Eichmann, C, Tzitzilonis, C, Nakamura, T, Maslennikov, I, Kwiatkowski, W, Choe, S, Lipton, S.A, Guntert, P, Riek, R. | Deposit date: | 2016-06-14 | Release date: | 2016-08-17 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein. J.Mol.Biol., 428, 2016
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5LAM
| Refined 3D NMR structure of the cytoplasmic rhodanese domain of the inner membrane protein YgaP from Escherichia coli | Descriptor: | Inner membrane protein YgaP | Authors: | Eichmann, C, Tzitzilonis, C, Nakamura, T, Maslennikov, I, Kwiatkowski, W, Choe, S, Lipton, S.A, Guntert, P, Riek, R. | Deposit date: | 2016-06-14 | Release date: | 2016-08-17 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein. J.Mol.Biol., 428, 2016
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5B2S
| Crystal structure of the Streptococcus pyogenes Cas9 EQR variant in complex with sgRNA and target DNA (TGAG PAM) | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CRISPR-associated endonuclease Cas9, ... | Authors: | Hirano, S, Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2016-02-02 | Release date: | 2016-03-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9 Mol.Cell, 61, 2016
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5AZ8
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5LKQ
| Protease domain of RadA | Descriptor: | DNA repair protein RadA | Authors: | Rapisarda, C, Fronzes, R. | Deposit date: | 2016-07-22 | Release date: | 2017-06-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.498 Å) | Cite: | Bacterial RadA is a DnaB-type helicase interacting with RecA to promote bidirectional D-loop extension. Nat Commun, 8, 2017
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7Z9C
| E.coli gyrase holocomplex with 217 bp DNA and albicidin | Descriptor: | DNA (5'-D(*AP*AP*TP*CP*AP*CP*CP*CP*GP*CP*AP*CP*AP*GP*AP*TP*TP*T)-3'), DNA (5'-D(*GP*AP*TP*TP*TP*TP*AP*TP*GP*CP*CP*TP*GP*AP*TP*TP*CP*T)-3'), DNA (5'-D(P*AP*AP*AP*TP*CP*TP*GP*TP*GP*CP*GP*GP*GP*T)-3'), ... | Authors: | Ghilarov, D, Heddle, J.G.H, Suessmuth, R. | Deposit date: | 2022-03-21 | Release date: | 2023-02-15 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Molecular mechanism of topoisomerase poisoning by the peptide antibiotic albicidin. Nat Catal, 6, 2023
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5AZP
| Crystal structure of a membrane protein from Pseudomonas aeruginosa | Descriptor: | (2S)-1-(pentanoyloxy)propan-2-yl hexanoate, ACETATE ION, FORMIC ACID, ... | Authors: | Yonehara, R, Yamashita, E, Nakagawa, A. | Deposit date: | 2015-10-21 | Release date: | 2016-06-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Crystal structures of OprN and OprJ, outer membrane factors of multidrug tripartite efflux pumps of Pseudomonas aeruginosa. Proteins, 84, 2016
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4Q62
| Crystal Structure of Leucine-rich repeat- and Coiled coil-containing Protein from Legionella pneumophila | Descriptor: | 1,2-ETHANEDIOL, Leucine-rich repeat-and coiled coil-containing protein, SULFATE ION | Authors: | Kim, Y, Hatzos-Skintges, C, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Program for the Characterization of Secreted Effector Proteins (PCSEP) | Deposit date: | 2014-04-20 | Release date: | 2014-05-07 | Method: | X-RAY DIFFRACTION (1.898 Å) | Cite: | Crystal Structure of Leucine-rich repeat- and Coiled coil-containing Protein from
Legionella pneumophila To be Published
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7K3D
| The structure of NTMT1 in complex with compound DC1-13 | Descriptor: | N-terminal Xaa-Pro-Lys N-methyltransferase 1, N~2~-{(2S)-1-[(naphthalen-1-yl)acetyl]-2,5-dihydro-1H-pyrrole-2-carbonyl}-L-lysyl-L-argininamide, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Chen, D, Huang, R, Noinaj, N. | Deposit date: | 2020-09-11 | Release date: | 2021-04-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Structure-based Discovery of Cell-Potent Peptidomimetic Inhibitors for Protein N-Terminal Methyltransferase 1. Acs Med.Chem.Lett., 12, 2021
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7Z94
| Crystal structure of Variovorax paradoxus indole monooxygenase (VpIndA1) in complex with indole | Descriptor: | DIMETHYL SULFOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, INDOLE, ... | Authors: | Kratky, J, Weisse, R, Strater, N. | Deposit date: | 2022-03-19 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structural and Mechanistic Studies on Substrate and Stereoselectivity of the Indole Monooxygenase VpIndA1: New Avenues for Biocatalytic Epoxidations and Sulfoxidations. Angew.Chem.Int.Ed.Engl., 62, 2023
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7Z4X
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5LJC
| Crystal structure of holo human CRBP1 | Descriptor: | RETINOL, Retinol-binding protein 1, SODIUM ION | Authors: | Zanotti, G, Vallese, F, Berni, R, Menozzi, I. | Deposit date: | 2016-07-18 | Release date: | 2017-01-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.433 Å) | Cite: | Structural and molecular determinants affecting the interaction of retinol with human CRBP1. J. Struct. Biol., 197, 2017
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5LJH
| Crystal structure of human apo CRBP1/K40L mutant | Descriptor: | Retinol-binding protein 1, SODIUM ION | Authors: | Zanotti, G, Vallese, F, Berni, R, Menozzi, I. | Deposit date: | 2016-07-18 | Release date: | 2017-01-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Structural and molecular determinants affecting the interaction of retinol with human CRBP1. J. Struct. Biol., 197, 2017
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5AXF
| Crystal Structure Analysis of DNA Duplexes containing sulfoamide-bridged nucleic acid (SuNA-NMe) | Descriptor: | DNA (5'-D(*GP*CP*GP*TP*AP*(LSM)P*AP*CP*GP*C)-3') | Authors: | Mitsuoka, Y, Aoyama, H, Kugimiya, A, Fujimura, Y, Yamamoto, T, Waki, R, Wada, F, Tahara, S, Sawamura, M, Noda, M, Hari, Y, Obika, S. | Deposit date: | 2015-07-28 | Release date: | 2016-07-20 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.13 Å) | Cite: | Effect of an N-substituent in sulfonamide-bridged nucleic acid (SuNA) on hybridization ability and duplex structure. Org.Biomol.Chem., 14, 2016
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7Z98
| Crystal structure of F191M variant Variovorax paradoxus indole monooxygenase (VpIndA1) in complex with methyl phenyl sulfide | Descriptor: | (methylsulfanyl)benzene, 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Kratky, J, Weisse, R, Strater, N. | Deposit date: | 2022-03-20 | Release date: | 2023-02-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Structural and Mechanistic Studies on Substrate and Stereoselectivity of the Indole Monooxygenase VpIndA1: New Avenues for Biocatalytic Epoxidations and Sulfoxidations. Angew.Chem.Int.Ed.Engl., 62, 2023
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5LUV
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