5W5O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5w5o by Molmil](/molmil-images/mine/5w5o) | |
5W5J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5w5j by Molmil](/molmil-images/mine/5w5j) | |
1ZLT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zlt by Molmil](/molmil-images/mine/1zlt) | Crystal Structure of Chk1 Complexed with a Hymenaldisine Analog | 分子名称: | (4Z)-4-(2-AMINO-5-OXO-3,5-DIHYDRO-4H-IMIDAZOL-4-YLIDENE)-2,3-DICHLORO-4,5,6,7-TETRAHYDROPYRROLO[2,3-C]AZEPIN-8(1H)-ONE, SULFATE ION, Serine/threonine-protein kinase Chk1 | 著者 | Lee, C.C, Ng, K, Wan, Y, Gray, N, Spraggon, G. | 登録日 | 2005-05-09 | 公開日 | 2006-06-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Crystal Structure of Chk1 Complexed with a Hymenaldisine Analog To be Published
|
|
1ZH0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1zh0 by Molmil](/molmil-images/mine/1zh0) | Crystal Structure of L-3-(2-napthyl)alanine-tRNA synthetase in complex with L-3-(2-napthyl)alanine | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-(2-NAPHTHYL)-ALANINE, Tyrosyl-tRNA synthetase | 著者 | Turner, J.M, Graziano, J, Spraggon, G, Schultz, P.G. | 登録日 | 2005-04-22 | 公開日 | 2006-04-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural plasticity of an aminoacyl-tRNA synthetase active site Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
3FCA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fca by Molmil](/molmil-images/mine/3fca) | Genetic Incorporation of a Metal-ion Chelating Amino Acid into proteins as biophysical probe | 分子名称: | Cysteine synthase, ZINC ION | 著者 | Wang, F, Lee, H, Spraggon, G, Schultz, P.G. | 登録日 | 2008-11-21 | 公開日 | 2009-02-17 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.149 Å) | 主引用文献 | Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe. J.Am.Chem.Soc., 131, 2009
|
|
2QB5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qb5 by Molmil](/molmil-images/mine/2qb5) | Crystal Structure of Human Inositol 1,3,4-Trisphosphate 5/6-Kinase (ITPK1) in Complex with ADP and Mn2+ | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Inositol-tetrakisphosphate 1-kinase, MANGANESE (II) ION, ... | 著者 | Chamberlain, P.P, Lesley, S.A, Spraggon, G. | 登録日 | 2007-06-15 | 公開日 | 2007-07-03 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Integration of inositol phosphate signaling pathways via human ITPK1. J.Biol.Chem., 282, 2007
|
|
2V9K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2v9k by Molmil](/molmil-images/mine/2v9k) | Crystal structure of human PUS10, a novel pseudouridine synthase. | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ... | 著者 | McCleverty, C.J, Hornsby, M, Spraggon, G, Kreusch, A. | 登録日 | 2007-08-23 | 公開日 | 2007-10-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Human Pus10, a Novel Pseudouridine Synthase. J.Mol.Biol., 373, 2007
|
|
3O0P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3o0p by Molmil](/molmil-images/mine/3o0p) | |
2PIS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2pis by Molmil](/molmil-images/mine/2pis) | Efforts toward Expansion of the Genetic Alphabet: Structure and Replication of Unnatural Base Pairs | 分子名称: | DNA (5'-D(*CP*GP*(CBR)P*GP*AP*AP*(FFD)P*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION | 著者 | Matsuda, S, Fillo, J.D, Henry, A.A, Wilkins, S.J, Rai, P, Dwyer, T.J, Geierstanger, B.H, Wemmer, D.E, Schultz, P.G, Spraggon, G, Romesberg, F.E. | 登録日 | 2007-04-13 | 公開日 | 2007-10-30 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs. J.Am.Chem.Soc., 129, 2007
|
|
1FZC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1fzc by Molmil](/molmil-images/mine/1fzc) | CRYSTAL STRUCTURE OF FRAGMENT DOUBLE-D FROM HUMAN FIBRIN WITH TWO DIFFERENT BOUND LIGANDS | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Everse, S.J, Spraggon, G, Veerapandian, L, Riley, M, Doolittle, R.F. | 登録日 | 1998-05-19 | 公開日 | 1998-10-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of fragment double-D from human fibrin with two different bound ligands. Biochemistry, 37, 1998
|
|
2Q7D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2q7d by Molmil](/molmil-images/mine/2q7d) | Crystal Structure of Human Inositol 1,3,4-Trisphosphate 5/6-kinase (ITPK1) in complex with AMPPNP and Mn2+ | 分子名称: | Inositol-tetrakisphosphate 1-kinase, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Chamberlain, P.P, Lesley, S.A, Spraggon, G. | 登録日 | 2007-06-06 | 公開日 | 2007-07-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Integration of inositol phosphate signaling pathways via human ITPK1. J.Biol.Chem., 282, 2007
|
|
2QTW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qtw by Molmil](/molmil-images/mine/2qtw) | The Crystal Structure of PCSK9 at 1.9 Angstroms Resolution Reveals structural homology to Resistin within the C-terminal domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Proprotein convertase subtilisin/kexin type 9, ... | 著者 | Hampton, E.N, Knuth, M.W, Li, J, Harris, J.L, Lesley, S.A, Spraggon, G. | 登録日 | 2007-08-02 | 公開日 | 2007-09-18 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain. Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2VP8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2vp8 by Molmil](/molmil-images/mine/2vp8) | Structure of Mycobacterium tuberculosis Rv1207 | 分子名称: | 1,2-ETHANEDIOL, DIHYDROPTEROATE SYNTHASE 2 | 著者 | Gengenbacher, M, Xu, T, Niyomwattanakit, P, Spraggon, G, Dick, T. | 登録日 | 2008-02-27 | 公開日 | 2008-08-12 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Biochemical and Structural Characterization of the Putative Dihydropteroate Synthase Ortholog Rv1207 of Mycobacterium Tuberculosis. Fems Microbiol.Lett., 287, 2008
|
|
3JXO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3jxo by Molmil](/molmil-images/mine/3jxo) | Crystal Structure of an Octomeric Two-Subunit TrkA K+ Channel Ring Gating Assembly, TM1088A:TM1088B, from Thermotoga maritima | 分子名称: | TrkA-N domain protein | 著者 | Deller, M.C, Johnson, H.A, Miller, M, Spraggon, G, Wilson, I.A, Lesley, S.A, Joint Center for Structural Genomics (JCSG) | 登録日 | 2009-09-20 | 公開日 | 2009-10-06 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal Structure of an Octomeric Two-Subunit TrkA K+ Channel Ring Gating Assembly, TM1088A:TM1088B, from Thermotoga maritima To be Published
|
|
2H7J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2h7j by Molmil](/molmil-images/mine/2h7j) | Crystal Structure of Cathepsin S in complex with a Nonpeptidic Inhibitor. | 分子名称: | 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, Cathepsin S, N-[(1S)-1-{1-[(1R,3E)-1-ACETYLPENT-3-EN-1-YL]-1H-1,2,3-TRIAZOL-4-YL}-1,2-DIMETHYLPROPYL]BENZAMIDE | 著者 | Patterson, A.W, Wood, W.J, Hornsby, M, Lesley, S, Spraggon, G, Ellman, J.A. | 登録日 | 2006-06-02 | 公開日 | 2006-10-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Identification of selective, nonpeptidic nitrile inhibitors of cathepsin s using the substrate activity screening method. J.Med.Chem., 49, 2006
|
|
2HXZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hxz by Molmil](/molmil-images/mine/2hxz) | Crystal Structure of Cathepsin S in complex with a Nonpeptidic Inhibitor (Hexagonal spacegroup) | 分子名称: | Cathepsin S, N-[(1S)-1-{1-[(1R,3E)-1-ACETYLPENT-3-EN-1-YL]-1H-1,2,3-TRIAZOL-4-YL}-1,2-DIMETHYLPROPYL]BENZAMIDE, SULFATE ION | 著者 | Patterson, A.W, Wood, W.J, Hornsby, M, Lesley, S, Spraggon, G, Ellman, J.A. | 登録日 | 2006-08-04 | 公開日 | 2006-10-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Identification of selective, nonpeptidic nitrile inhibitors of cathepsin s using the substrate activity screening method. J.Med.Chem., 49, 2006
|
|
4AE0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ae0 by Molmil](/molmil-images/mine/4ae0) | |
4AE1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ae1 by Molmil](/molmil-images/mine/4ae1) | |
1S96
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s96 by Molmil](/molmil-images/mine/1s96) | The 2.0 A X-ray structure of Guanylate Kinase from E.coli | 分子名称: | Guanylate kinase, PHOSPHATE ION, UNKNOWN ATOM OR ION | 著者 | Kreusch, A, Spraggon, G, Klock, H.E, McMullan, D, Vincent, J, Rodrigues, K, Lesley, S.A. | 登録日 | 2004-02-03 | 公開日 | 2004-02-10 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Structure of Guanylate Kinase from Escherichia coli at 2.0 A resolution To be Published
|
|
3R5L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3r5l by Molmil](/molmil-images/mine/3r5l) | Structure of Ddn, the Deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824 | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Deazaflavin-dependent nitroreductase | 著者 | Cellitti, S.E, Shaffer, J, Jones, D.H, Mukherjee, T, Gurumurthy, M, Bursulaya, B, Boshoff, H.I.M, Choi, I, Nayyar, A, Lee, Y.S, Cherian, J, Niyomrattanakit, P, Dick, T, Manjunatha, U.H, Barry, C.E, Spraggon, G, Geierstanger, B.H. | 登録日 | 2011-03-18 | 公開日 | 2012-01-18 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824. Structure, 20, 2012
|
|
3R5R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3r5r by Molmil](/molmil-images/mine/3r5r) | Structure of Ddn, the Deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824, with co-factor F420 | 分子名称: | COENZYME F420, Deazaflavin-dependent nitroreductase | 著者 | Cellitti, S.E, Shaffer, J, Jones, D.H, Mukherjee, T, Gurumurthy, M, Bursulaya, B, Boshoff, H.I.M, Choi, I, Nayya, A, Lee, Y.S, Cherian, J, Niyomrattanakit, P, Dick, T, Manjunatha, U.H, Barry, C.E, Spraggon, G, Geierstanger, B.H. | 登録日 | 2011-03-19 | 公開日 | 2012-01-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824. Structure, 20, 2012
|
|
3R5P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3r5p by Molmil](/molmil-images/mine/3r5p) | Structure of Ddn, the Deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824 | 分子名称: | Deazaflavin-dependent nitroreductase, SULFATE ION | 著者 | Cellitti, S.E, Shaffer, J, Jones, D.H, Mukherjee, T, Gurumurthy, M, Bursulaya, B, Boshoff, H.I.M, Choi, I, Nayya, A, Lee, Y.S, Cherian, J, Niyomrattanakit, P, Dick, T, Manjunatha, U.H, Barry, C.E, Spraggon, G, Geierstanger, B.H. | 登録日 | 2011-03-19 | 公開日 | 2012-01-18 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824. Structure, 20, 2012
|
|
3R5Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3r5y by Molmil](/molmil-images/mine/3r5y) | Structure of a Deazaflavin-dependent nitroreductase from Nocardia farcinica, with co-factor F420 | 分子名称: | COENZYME F420, Putative uncharacterized protein | 著者 | Cellitti, S.E, Shaffer, J, Jones, D.H, Mukherjee, T, Gurumurthy, M, Bursulaya, B, Boshoff, H.I.M, Choi, I, Nayya, A, Lee, Y.S, Cherian, J, Niyomrattanakit, P, Dick, T, Manjunatha, U.H, Barry, C.E, Spraggon, G, Geierstanger, B.H. | 登録日 | 2011-03-20 | 公開日 | 2012-01-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824. Structure, 20, 2012
|
|
3QE4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qe4 by Molmil](/molmil-images/mine/3qe4) | An evolved aminoacyl-tRNA Synthetase with atypical polysubstrate specificity | 分子名称: | 4-cyano-L-phenylalanine, Tyrosyl-tRNA synthetase | 著者 | Young, D.D, Young, T.S, Jahnz, M, Ahmad, I, Spraggon, G, Schultz, P.G. | 登録日 | 2011-01-19 | 公開日 | 2011-02-16 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | An Evolved Aminoacyl-tRNA Synthetase with Atypical Polysubstrate Specificity . Biochemistry, 50, 2011
|
|
3R5W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3r5w by Molmil](/molmil-images/mine/3r5w) | Structure of Ddn, the Deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824, with co-factor F420 | 分子名称: | COENZYME F420, Deazaflavin-dependent nitroreductase | 著者 | Cellitti, S.E, Shaffer, J, Jones, D.H, Mukherjee, T, Gurumurthy, M, Bursulaya, B, Boshoff, H.I.M, Choi, I, Nayya, A, Lee, Y.S, Cherian, J, Niyomrattanakit, P, Dick, T, Manjunatha, U.H, Barry, C.E, Spraggon, G, Geierstanger, B.H. | 登録日 | 2011-03-20 | 公開日 | 2012-01-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.786 Å) | 主引用文献 | Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824. Structure, 20, 2012
|
|