6OVC
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![BU of 6ovc by Molmil](/molmil-images/mine/6ovc) | hMcl1 inhibitor complex | 分子名称: | (2S)-N-(benzylsulfonyl)-4-(cyclobutylmethyl)-2-(2,4-dichlorophenyl)-3,4-dihydro-2H-1,4-benzoxazine-6-carboxamide, Induced myeloid leukemia cell differentiation protein Mcl-1 | 著者 | Poppe, L. | 登録日 | 2019-05-07 | 公開日 | 2019-05-22 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | AMG 176, a Selective MCL1 Inhibitor, Is Effective in Hematologic Cancer Models Alone and in Combination with Established Therapies. Cancer Discov, 8, 2018
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7SWI
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![BU of 7swi by Molmil](/molmil-images/mine/7swi) | cTnC-TnI chimera complexed with A2 | 分子名称: | 4-(3-cyano-3-methylazetidine-1-carbonyl)-N-[(3R,4S)-7-fluoro-4-hydroxy-6-methyl-3,4-dihydro-2H-1-benzopyran-3-yl]-5-methyl-1H-pyrrole-2-sulfonamide, Troponin C, slow skeletal and cardiac muscles,Troponin I, ... | 著者 | Poppe, L, Hartman, J.J, Romero, A, Reagan, J.D. | 登録日 | 2021-11-19 | 公開日 | 2022-04-06 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and Thermodynamic Model for the Activation of Cardiac Troponin. Biochemistry, 61, 2022
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7SVC
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![BU of 7svc by Molmil](/molmil-images/mine/7svc) | NMR structure of cTnC-TnI chimera bound to calcium and A2 | 分子名称: | 4-(3-cyano-3-methylazetidine-1-carbonyl)-N-[(3R,4S)-7-fluoro-4-hydroxy-6-methyl-3,4-dihydro-2H-1-benzopyran-3-yl]-5-methyl-1H-pyrrole-2-sulfonamide, CALCIUM ION, Troponin C, ... | 著者 | Poppe, L, Hartman, J.J, Romero, A, Reagan, J.D. | 登録日 | 2021-11-18 | 公開日 | 2022-04-06 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and Thermodynamic Model for the Activation of Cardiac Troponin. Biochemistry, 61, 2022
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7SUP
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![BU of 7sup by Molmil](/molmil-images/mine/7sup) | NMR structure of cTnC-TnI chimera bound to calcium and A1 | 分子名称: | 4-(3-cyano-3-methylazetidine-1-carbonyl)-N-[(3S)-7-fluoro-6-methyl-3,4-dihydro-2H-1-benzopyran-3-yl]-5-methyl-1H-pyrrole-2-sulfonamide, CALCIUM ION, Troponin C, ... | 著者 | Poppe, L, Hartman, J.J, Romero, A, Reagan, J.D. | 登録日 | 2021-11-17 | 公開日 | 2022-04-06 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and Thermodynamic Model for the Activation of Cardiac Troponin. Biochemistry, 61, 2022
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7SWG
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![BU of 7swg by Molmil](/molmil-images/mine/7swg) | cTnC-TnI chimera complexed with A1 | 分子名称: | 4-(3-cyano-3-methylazetidine-1-carbonyl)-N-[(3S)-7-fluoro-6-methyl-3,4-dihydro-2H-1-benzopyran-3-yl]-5-methyl-1H-pyrrole-2-sulfonamide, Troponin C, slow skeletal and cardiac muscles,Troponin I, ... | 著者 | Poppe, L, Hartman, J.J, Romero, A, Reagan, J.D. | 登録日 | 2021-11-19 | 公開日 | 2022-04-06 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and Thermodynamic Model for the Activation of Cardiac Troponin. Biochemistry, 61, 2022
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7SXD
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![BU of 7sxd by Molmil](/molmil-images/mine/7sxd) | NMR solution structure TnC-TnI chimera | 分子名称: | Troponin C, slow skeletal and cardiac muscles,Troponin I, cardiac muscle chimera | 著者 | Poppe, L, Hartman, J.J, Romero, A, Reagan, J.D. | 登録日 | 2021-11-22 | 公開日 | 2022-04-06 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and Thermodynamic Model for the Activation of Cardiac Troponin. Biochemistry, 61, 2022
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7SXC
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![BU of 7sxc by Molmil](/molmil-images/mine/7sxc) | cTnC-TnI chimera complexed with calcium | 分子名称: | CALCIUM ION, Troponin C, slow skeletal and cardiac muscles,Troponin I, ... | 著者 | Poppe, L, Hartman, J.J, Romero, A, Reagan, J.D. | 登録日 | 2021-11-22 | 公開日 | 2022-04-06 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and Thermodynamic Model for the Activation of Cardiac Troponin. Biochemistry, 61, 2022
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2LZG
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![BU of 2lzg by Molmil](/molmil-images/mine/2lzg) | NMR Structure of Mdm2 (6-125) with Pip-1 | 分子名称: | E3 ubiquitin-protein ligase Mdm2, [(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(cyclopropylmethyl)-2-oxopiperidin-3-yl]acetic acid | 著者 | Michelsen, K.B, Jordan, J.B, Lewis, J, Long, A.M, Yang, E, Rew, Y, Zhou, J, Yakowec, P, Schnier, P.D, Huang, X, Poppe, L. | 登録日 | 2012-10-02 | 公開日 | 2012-11-07 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Ordering of the N-Terminus of Human MDM2 by Small Molecule Inhibitors. J.Am.Chem.Soc., 134, 2012
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2KEF
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![BU of 2kef by Molmil](/molmil-images/mine/2kef) | Solution NMR structures of human hepcidin at 325K | 分子名称: | Hepcidin | 著者 | Jordan, J.B, Poppe, L, Hainu, M, Arvedson, T, Syed, R, Li, V, Kohno, H, Kim, H, Miranda, L.P, Cheetham, J, Sasu, B.J. | 登録日 | 2009-01-29 | 公開日 | 2009-06-23 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Hepcidin revisited, disulfide connectivity, dynamics, and structure. J.Biol.Chem., 284, 2009
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2MHS
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![BU of 2mhs by Molmil](/molmil-images/mine/2mhs) | NMR Structure of human Mcl-1 | 分子名称: | Induced myeloid leukemia cell differentiation protein Mcl-1 | 著者 | Liu, G, Poppe, L, Aoki, K, Yamane, H, Lewis, J, Szyperski, T. | 登録日 | 2013-12-04 | 公開日 | 2014-05-14 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | High-Quality NMR Structure of Human Anti-Apoptotic Protein Domain Mcl-1(171-327) for Cancer Drug Design. Plos One, 9, 2014
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6HQF
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![BU of 6hqf by Molmil](/molmil-images/mine/6hqf) | Structure of Phenylalanine ammonia-lyase from Petroselinum crispum in complex with (R)-APEP | 分子名称: | Phenylalanine ammonia-lyase 1, [(1R)-1-amino-2-phenylethyl]phosphonic acid | 著者 | Bata, Z, Molnar, B, Leveles, I, Poppe, L, Vertessy, G.B. | 登録日 | 2018-09-24 | 公開日 | 2019-10-09 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Substrate Tunnel Engineering Aided by X-ray Crystallography and Functional Dynamics Swaps the Function of MIO-Enzymes Acs Catalysis, 2021
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6F6T
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![BU of 6f6t by Molmil](/molmil-images/mine/6f6t) | |
6H2O
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![BU of 6h2o by Molmil](/molmil-images/mine/6h2o) | APO structure of Phenylalanine ammonia-lyase from Petroselinum crispum | 分子名称: | Phenylalanine ammonia-lyase 1 | 著者 | Molnar, B, Bata, Z, Leveles, I, Poppe, L, Vertessy, G.B. | 登録日 | 2018-07-14 | 公開日 | 2019-07-31 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Substrate Tunnel Engineering Aided by X-ray Crystallography and Functional Dynamics Swaps the Function of MIO-Enzymes Acs Catalysis, 2021
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