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PDB: 20 件
1LUD
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SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 24 STRUCTURES
分子名称: 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM, DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Polshakov, V.I, Smirnov, E.G, Birdsall, B, Kelly, G, Feeney, J.
登録日2002-05-22
公開日2002-12-18
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH
J.Biomol.Nmr, 24, 2002
7QCB
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Williams-Beuren syndrome related methyltransferase WBSCR27 in complex with SAH
分子名称: Methyltransferase-like 27, S-ADENOSYL-L-HOMOCYSTEINE
著者Polshakov, V.I, Mariasina, S.S, Chang, C.-F, Efimov, S.V.
登録日2021-11-23
公開日2021-12-29
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Williams-Beuren Syndrome Related Methyltransferase WBSCR27: From Structure to Possible Function.
Front Mol Biosci, 9, 2022
1YHO
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Solution structure of human dihydrofolate reductase complexed with trimethoprim and nadph, 25 structures
分子名称: 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Polshakov, V.I, Birdsall, B.
登録日2005-01-10
公開日2005-11-22
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of human dihydrofolate reductase in its complex with trimethoprim and NADPH.
J.Biomol.Nmr, 33, 2005
1BZF
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BU of 1bzf by Molmil
NMR SOLUTION STRUCTURE AND DYNAMICS OF THE COMPLEX OF LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE WITH THE NEW LIPOPHILIC ANTIFOLATE DRUG TRIMETREXATE, 22 STRUCTURES
分子名称: DIHYDROFOLATE REDUCTASE, TRIMETREXATE
著者Polshakov, V.I, Birdsall, B, Frenkiel, T.A, Gargaro, A.R, Feeney, J.
登録日1998-10-28
公開日1999-05-18
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure and dynamics in solution of the complex of Lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug trimetrexate.
Protein Sci., 8, 1999
5LGF
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Solution structure of the N-terminal domain of Ogataea polymorpha telomerase reverse transcriptase
分子名称: Telomerase reverse transcriptase
著者Polshakov, V.I, Mantsyzov, A.B, Efimov, S.V.
登録日2016-07-07
公開日2017-07-19
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and function of the N-terminal domain of the yeast telomerase reverse transcriptase.
Nucleic Acids Res., 46, 2018
7QCC
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Williams-Beuren syndrome related methyltransferase WBSCR27 in apo-form
分子名称: Methyltransferase-like 27
著者Polshakov, V.I, Mariasina, S.S, Chang, C.-F.
登録日2021-11-23
公開日2021-12-29
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Williams-Beuren Syndrome Related Methyltransferase WBSCR27: From Structure to Possible Function.
Front Mol Biosci, 9, 2022
5LFY
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Zinc bound dimer of the fragment of human amyloid-beta peptide with Alzheimer's disease pathogenic Taiwanese mutation D7H
分子名称: Amyloid beta A4 protein, ZINC ION
著者Polshakov, V.I, Mantsyzov, A.B, Kozin, S.A.
登録日2016-07-05
公開日2017-08-23
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Binuclear Zinc Interaction Fold Discovered in the Homodimer of Alzheimer's Amyloid-beta Fragment with Taiwanese Mutation D7H.
Angew. Chem. Int. Ed. Engl., 56, 2017
2L28
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Solution structure of lactobacillus casei dihydrofolate reductase apo-form, 25 conformers
分子名称: Dihydrofolate reductase
著者Polshakov, V.I, Birdsall, B, Feeney, J.
登録日2010-08-13
公開日2011-04-06
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR Structures of Apo L. casei Dihydrofolate Reductase and Its Complexes with Trimethoprim and NADPH: Contributions to Positive Cooperative Binding from Ligand-Induced Refolding, Conformational Changes, and Interligand Hydrophobic Interactions.
Biochemistry, 50, 2011
2LLX
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Solution structure of the N-terminal domain of human polypeptide chain release factor eRF1
分子名称: Eukaryotic peptide chain release factor subunit 1
著者Polshakov, V.I, Eliseev, B.D, Birdsall, B, Frolova, L.Y.
登録日2011-11-18
公開日2012-05-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and dynamics in solution of the stop codon decoding N-terminal domain of the human polypeptide chain release factor eRF1.
Protein Sci., 21, 2012
2HM9
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Solution structure of dihydrofolate reductase complexed with trimethoprim, 33 structures
分子名称: 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM, Dihydrofolate reductase
著者Polshakov, V.I, Birdsall, B.
登録日2006-07-11
公開日2007-06-05
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR structures of apo L.casei dihydrofolate reductase and its complexes with trimethoprim and NADPH. Contributions to positive cooperative binding from ligand-induced refolding, conformational changes and interligand hydrophobic interactions
Biochemistry, 2011
2HST
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Solution structure of the middle domain of human eukaryotic translation termination factor eRF1
分子名称: Eukaryotic peptide chain release factor subunit 1
著者Polshakov, V.I, Birdsall, B, Kisselev, L.L.
登録日2006-07-23
公開日2007-06-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Eukaryotic class 1 translation termination factor eRF1 - the NMR structure and dynamics of the middle domain involved in triggering ribosome-dependent peptidyl-tRNA hydrolysis
Febs J., 274, 2007
2HQP
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BU of 2hqp by Molmil
Solution structure of L.casei dihydrofolate reductase complexed with NADPH, 32 structures
分子名称: Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Polshakov, V.I, Birdsall, B.
登録日2006-07-19
公開日2007-06-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural insights into cooperative effects of ligand binding to L. casei dihydrofolate redutase
TO BE PUBLISHED
6Q44
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Est3 telomerase subunit in the yeast Hansenula polymorpha
分子名称: Uncharacterized protein
著者Mantsyzov, A.B, Mariasina, S.S, Petrova, O.A, Efimov, S.V, Dontsova, O.A, Polshakov, V.I.
登録日2018-12-05
公開日2019-12-25
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Insights into the structure and function of Est3 from the Hansenula polymorpha telomerase.
Sci Rep, 10, 2020
1PS2
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BU of 1ps2 by Molmil
HIGH RESOLUTION NMR SOLUTION STRUCTURE OF HUMAN PS2, 19 STRUCTURES
分子名称: PS2
著者Williams, M.A, Polshakov, V.I, Gargaro, A.R, Feeney, J.
登録日1997-01-07
公開日1997-07-07
最終更新日2021-11-03
実験手法SOLUTION NMR
主引用文献High-resolution solution structure of human pNR-2/pS2: a single trefoil motif protein.
J.Mol.Biol., 267, 1997
1DIS
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BU of 1dis by Molmil
DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE
分子名称: BRODIMOPRIM-4,6-DICARBOXYLATE, DIHYDROFOLATE REDUCTASE
著者Morgan, W.D, Birdsall, B, Polshakov, V.I, Sali, D, Kompis, I, Feeney, J.
登録日1995-08-01
公開日1995-11-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase.
Biochemistry, 34, 1995
1DIU
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DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE
分子名称: BRODIMOPRIM-4,6-DICARBOXYLATE, DIHYDROFOLATE REDUCTASE
著者Morgan, W.D, Birdsall, B, Polshakov, V.I, Sali, D, Kompis, I, Feeney, J.
登録日1995-08-01
公開日1995-11-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase.
Biochemistry, 34, 1995
1AO8
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DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE, NMR, 21 STRUCTURES
分子名称: DIHYDROFOLATE REDUCTASE, METHOTREXATE
著者Gargaro, A.R, Soteriou, A, Frenkiel, T.A, Bauer, C.J, Birdsall, B, Polshakov, V.I, Barsukov, I.L, Roberts, G.C.K, Feeney, J.
登録日1997-07-22
公開日1998-02-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure of the complex of Lactobacillus casei dihydrofolate reductase with methotrexate.
J.Mol.Biol., 277, 1998
7NF9
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BU of 7nf9 by Molmil
N-terminal C2H2 Zn-finger domain of Clamp
分子名称: Chromatin-linked adaptor for MSL proteins, isoform A, ZINC ION
著者Mariasina, S.S, Bonchuk, A.N, Tikhonova, E.A, Efimov, S.V, Maksimenko, O.G, Georgiev, P.G, Polshakov, V.I.
登録日2021-02-05
公開日2021-12-29
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structural basis for interaction between CLAMP and MSL2 proteins involved in the specific recruitment of the dosage compensation complex in Drosophila.
Nucleic Acids Res., 50, 2022
2KTV
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Human eRF1 C-domain, "open" conformer
分子名称: Eukaryotic peptide chain release factor subunit 1
著者Mantsyzov, A.B, Polshakov, V.I, Birdsall, B.
登録日2010-02-09
公開日2010-06-09
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor.
Febs J., 277, 2010
2KTU
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Human eRF1 C-domain, "closed" conformer
分子名称: Eukaryotic peptide chain release factor subunit 1
著者Mantsyzov, A.B, Polshakov, V.I, Birdsall, B.
登録日2010-02-09
公開日2010-06-09
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR assignments of the C-terminal domain of human polypeptide release factor eRF1.
Biomol.Nmr Assign., 1, 2007

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