7Z3J
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![BU of 7z3j by Molmil](/molmil-images/mine/7z3j) | Structure of crystallisable rat Phospholipase C gamma 1 in complex with inositol 1,4,5-trisphosphate | Descriptor: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | Authors: | Pinotsis, N, Bunney, T.D, Katan, M. | Deposit date: | 2022-03-02 | Release date: | 2022-07-20 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Characterization of the membrane interactions of phospholipase C gamma reveals key features of the active enzyme. Sci Adv, 8, 2022
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1YA5
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![BU of 1ya5 by Molmil](/molmil-images/mine/1ya5) | Crystal structure of the titin domains z1z2 in complex with telethonin | Descriptor: | N2B-TITIN ISOFORM, SULFATE ION, TELETHONIN | Authors: | Pinotsis, N, Popov, A, Zou, P, Wilmanns, M. | Deposit date: | 2004-12-17 | Release date: | 2005-12-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.445 Å) | Cite: | Palindromic assembly of the giant muscle protein titin in the sarcomeric Z-disk Nature, 439, 2006
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1P2G
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![BU of 1p2g by Molmil](/molmil-images/mine/1p2g) | Crystal Structure of Glycogen Phosphorylase B in complex with Gamma Cyclodextrin | Descriptor: | Cyclooctakis-(1-4)-(alpha-D-glucopyranose), Glycogen phosphorylase, muscle form, ... | Authors: | Pinotsis, N, Leonidas, D.D, Chrysina, E.D, Oikonomakos, N.G, Mavridis, I.M. | Deposit date: | 2003-04-15 | Release date: | 2003-09-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The binding of beta- and gamma-cyclodextrins to glycogen phosphorylase b: Kinetic and crystallographic studies. Protein Sci., 12, 2003
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4D1E
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![BU of 4d1e by Molmil](/molmil-images/mine/4d1e) | THE CRYSTAL STRUCTURE OF HUMAN MUSCLE ALPHA-ACTININ-2 | Descriptor: | ALPHA-ACTININ-2 | Authors: | Pinotsis, N, Salmazo, A, Sjoeblom, B, Gkougkoulia, E, Djinovic-Carugo, K. | Deposit date: | 2014-05-01 | Release date: | 2014-12-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | The Structure and Regulation of Human Muscle Alpha-Actinin Cell(Cambridge,Mass.), 159, 2014
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2F8V
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![BU of 2f8v by Molmil](/molmil-images/mine/2f8v) | Structure of full length telethonin in complex with the N-terminus of titin | Descriptor: | N2B-Titin Isoform, SULFATE ION, Telethonin | Authors: | Pinotsis, N, Petoukhov, M, Lange, S, Svergun, D, Zou, P, Gautel, M, Wilmanns, M. | Deposit date: | 2005-12-04 | Release date: | 2006-06-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Evidence for a dimeric assembly of two titin/telethonin complexes induced by the telethonin C-terminus. J.Struct.Biol., 155, 2006
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1P2D
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![BU of 1p2d by Molmil](/molmil-images/mine/1p2d) | Crystal Structure of Glycogen Phosphorylase B in complex with Beta Cyclodextrin | Descriptor: | Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Pinotsis, N, Leonidas, D.D, Chrysina, E.D, Oikonomakos, N.G, Mavridis, I.M. | Deposit date: | 2003-04-15 | Release date: | 2003-09-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | The binding of beta- and gamma-cyclodextrins to glycogen phosphorylase b: Kinetic and crystallographic studies. Protein Sci., 12, 2003
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1P2B
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![BU of 1p2b by Molmil](/molmil-images/mine/1p2b) | Crystal Structure of Glycogen Phosphorylase B in Complex with Maltoheptaose | Descriptor: | Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Pinotsis, N, Leonidas, D.D, Chrysina, E.D, Oikonomakos, N.G, Mavridis, I.M. | Deposit date: | 2003-04-15 | Release date: | 2003-09-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The binding of beta- and gamma-cyclodextrins to glycogen phosphorylase b: Kinetic and crystallographic studies. Protein Sci., 12, 2003
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1P29
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![BU of 1p29 by Molmil](/molmil-images/mine/1p29) | Crystal Structure of glycogen phosphorylase b in complex with maltopentaose | Descriptor: | Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, ... | Authors: | Pinotsis, N, Leonidas, D.D, Chrysina, E.D, Oikonomakos, N.G, Mavridis, I.M. | Deposit date: | 2003-04-15 | Release date: | 2003-09-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The binding of beta- and gamma-cyclodextrins to glycogen phosphorylase b: Kinetic and crystallographic studies. Protein Sci., 12, 2003
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7Q4H
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![BU of 7q4h by Molmil](/molmil-images/mine/7q4h) | |
7Q4J
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![BU of 7q4j by Molmil](/molmil-images/mine/7q4j) | |
2R15
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![BU of 2r15 by Molmil](/molmil-images/mine/2r15) | |
8B9S
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![BU of 8b9s by Molmil](/molmil-images/mine/8b9s) | |
2Y23
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![BU of 2y23 by Molmil](/molmil-images/mine/2y23) | |
2Y25
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![BU of 2y25 by Molmil](/molmil-images/mine/2y25) | |
5NNY
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![BU of 5nny by Molmil](/molmil-images/mine/5nny) | |
2O9V
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![BU of 2o9v by Molmil](/molmil-images/mine/2o9v) | |
2O2W
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![BU of 2o2w by Molmil](/molmil-images/mine/2o2w) | |
2O31
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![BU of 2o31 by Molmil](/molmil-images/mine/2o31) | |
2O9S
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![BU of 2o9s by Molmil](/molmil-images/mine/2o9s) | The second SH3 domain from ponsin | Descriptor: | CHLORIDE ION, Ponsin, SODIUM ION, ... | Authors: | Pinotsis, N, Wilmanns, M. | Deposit date: | 2006-12-14 | Release date: | 2007-10-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (0.83 Å) | Cite: | Paxillin and ponsin interact in nascent costameres of muscle cells J.Mol.Biol., 369, 2007
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6SL7
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![BU of 6sl7 by Molmil](/molmil-images/mine/6sl7) | |
6SL2
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![BU of 6sl2 by Molmil](/molmil-images/mine/6sl2) | ALPHA-ACTININ FROM ENTAMOEBA HISTOLYTICA | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Calponin homology domain protein putative, ... | Authors: | Pinotsis, N, Khan, M.B, Djinovic-Carugo, K. | Deposit date: | 2019-08-18 | Release date: | 2020-08-26 | Last modified: | 2020-11-04 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Calcium modulates the domain flexibility and function of an alpha-actinin similar to the ancestral alpha-actinin. Proc.Natl.Acad.Sci.USA, 117, 2020
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6SL3
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![BU of 6sl3 by Molmil](/molmil-images/mine/6sl3) | |
5NL6
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![BU of 5nl6 by Molmil](/molmil-images/mine/5nl6) | |
5N72
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5NL7
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![BU of 5nl7 by Molmil](/molmil-images/mine/5nl7) | The crystal structure of the Actin Binding Domain (ABD) of alpha actinin from Entamoeba histolytica | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Calponin homology domain protein putative | Authors: | Pinotsis, N, Djinovic-Carugo, K, Khan, M.B. | Deposit date: | 2017-04-04 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Calcium modulates the domain flexibility and function of an alpha-actinin similar to the ancestral alpha-actinin. Proc.Natl.Acad.Sci.USA, 117, 2020
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