6ZS5
 
 | | 3.5 A cryo-EM structure of human uromodulin filament core | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Uromodulin, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Stanisich, J.J, Zyla, D, Afanasyev, P, Xu, J, Pilhofer, M, Boeringer, D, Glockshuber, R. | | Deposit date: | 2020-07-15 | | Release date: | 2020-09-02 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | The cryo-EM structure of the human uromodulin filament core reveals a unique assembly mechanism.
Elife, 9, 2020
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8RWJ
 | | cryoEM structure of Acs1 filament determined by FilamentID | | Descriptor: | Acetyl-coenzyme A synthetase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] ethanoate | | Authors: | Hugener, J, Xu, J, Wettstein, R, Ioannidi, L, Velikov, D, Wollweber, F, Henggeler, A, Matos, J, Pilhofer, M. | | Deposit date: | 2024-02-05 | | Release date: | 2024-06-26 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | FilamentID reveals the composition and function of metabolic enzyme polymers during gametogenesis.
Cell, 187, 2024
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8RWK
 | | cryoEM structure of the central Ald4 filament determined by FilamentID | | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Potassium-activated aldehyde dehydrogenase, mitochondrial | | Authors: | Hugener, J, Xu, J, Wettstein, R, Ioannidi, L, Velikov, D, Wollweber, F, Henggeler, A, Matos, J, Pilhofer, M. | | Deposit date: | 2024-02-05 | | Release date: | 2024-06-26 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | FilamentID reveals the composition and function of metabolic enzyme polymers during gametogenesis.
Cell, 187, 2024
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8BKY
 | | Cryo-EM structure of a contractile injection system in Streptomyces coelicolor, the contracted sheath shell. | | Descriptor: | Phage tail sheath protein | | Authors: | Casu, B, Sallmen, J.W, Schlimpert, S, Pilhofer, M. | | Deposit date: | 2022-11-09 | | Release date: | 2023-03-15 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cytoplasmic contractile injection systems mediate cell death in Streptomyces.
Nat Microbiol, 8, 2023
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8BL4
 | | Cryo-EM structure of a contractile injection system in Streptomyces coelicolor, the sheath-tube module in extended state. | | Descriptor: | Phage tail protein, Phage tail sheath family protein | | Authors: | Casu, B, Sallmen, J.W, Schlimpert, S, Pilhofer, M. | | Deposit date: | 2022-11-09 | | Release date: | 2023-03-15 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Cytoplasmic contractile injection systems mediate cell death in Streptomyces.
Nat Microbiol, 8, 2023
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9FLW
 | | CryoEM structure of the fragment-6 (3571-4078) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | Descriptor: | The grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | Authors: | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | Deposit date: | 2024-06-05 | | Release date: | 2024-10-16 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Mechanism of bacterial predation via ixotrophy.
Science, 386, 2024
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9FLS
 | | CryoEM structure of the fragment-3 (2061-2397) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | Descriptor: | The grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | Authors: | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | Deposit date: | 2024-06-05 | | Release date: | 2024-10-16 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Mechanism of bacterial predation via ixotrophy.
Science, 386, 2024
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9FLY
 | | CryoEM structure of the base (4151-5009) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | Descriptor: | The grappling hook protein A in the bacterium Aureispira sp. CCB-QB1 | | Authors: | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | Deposit date: | 2024-06-05 | | Release date: | 2024-10-16 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Mechanism of bacterial predation via ixotrophy.
Science, 386, 2024
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9FLU
 | | CryoEM structure of the fragment-1 (3402-3733) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | Descriptor: | The grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | Authors: | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | Deposit date: | 2024-06-05 | | Release date: | 2024-10-16 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Mechanism of bacterial predation via ixotrophy.
Science, 386, 2024
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9FLV
 | | CryoEM structure of the fragment-5 (2393-2807) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | Descriptor: | The grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | Authors: | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | Deposit date: | 2024-06-05 | | Release date: | 2024-10-16 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Mechanism of bacterial predation via ixotrophy.
Science, 386, 2024
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9FLP
 | | CryoEM structure of the neck (1403-2314) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | Descriptor: | The grappling hook protein A in the bacterium Aureispira sp. CCB-QB1 | | Authors: | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | Deposit date: | 2024-06-05 | | Release date: | 2024-10-16 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Mechanism of bacterial predation via ixotrophy.
Science, 386, 2024
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9FLX
 | | CryoEM structure of the fragment-4 (4074-4421) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | Descriptor: | The grappling hook protein A in the bacterium Aureispira sp. CCB-QB1 | | Authors: | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | Deposit date: | 2024-06-05 | | Release date: | 2024-10-16 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Mechanism of bacterial predation via ixotrophy.
Science, 386, 2024
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9G8B
 | | CryoEM structure of the fragment-2 (2892-3236) in the grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | Descriptor: | The grappling hook protein A (GhpA) in the bacterium Aureispira sp. CCB-QB1 | | Authors: | Lien, Y.-W, Amendola, D, Lee, K.S, Bartlau, N, Xu, J, Furusawa, G, Polz, M.F, Stocker, R, Weiss, G.L, Pilhofer, M. | | Deposit date: | 2024-07-23 | | Release date: | 2024-10-16 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Mechanism of bacterial predation via ixotrophy.
Science, 386, 2024
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9F6U
 | | cryoEM structure of Asgard tubulin heterodimer AtubA/B with GDP | | Descriptor: | Asgard tubulin A (AtubA) from Candidatus Lokiarchaeum ossiferum, Asgard tubulin B (AtubB) from Candidatus Lokiarchaeum ossiferum, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Wollweber, F, Xu, J, Ponce-Toled, R.I, Rodrigues-Oliveira, T, Malit, J.J.L, Kokhanovska, A, Schleper, C, Pilhofer, M. | | Deposit date: | 2024-05-02 | | Release date: | 2025-04-02 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Microtubules in Asgard archaea.
Cell, 188, 2025
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7B5I
 | | Cryo-EM structure of the contractile injection system cap complex from Anabaena PCC7120 | | Descriptor: | All3324 protein, All3325 protein, All3326 protein, ... | | Authors: | Eisenstein, F, Weiss, G.L, Pilhofer, M. | | Deposit date: | 2020-12-03 | | Release date: | 2022-02-23 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structure of a thylakoid-anchored contractile injection system in multicellular cyanobacteria.
Nat Microbiol, 7, 2022
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7B5H
 | | Cryo-EM structure of the contractile injection system base plate from Anabaena PCC7120 | | Descriptor: | All3314 protein, All3315 protein, All3316 protein, ... | | Authors: | Eisenstein, F, Weiss, G.L, Pilhofer, M. | | Deposit date: | 2020-12-03 | | Release date: | 2022-02-23 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure of a thylakoid-anchored contractile injection system in multicellular cyanobacteria.
Nat Microbiol, 7, 2022
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9F6T
 | | cryoEM structure of Asgard tubulin heterodimer AtubA/B with GTP | | Descriptor: | Asgard tubulin A (AtubA) from Candidatus Lokiarchaeum ossiferum, Asgard tubulin B (AtubB) from Candidatus Lokiarchaeum ossiferum, GUANOSINE-5'-TRIPHOSPHATE | | Authors: | Wollweber, F, Xu, J, Ponce-Toled, R.I, Rodrigues-Oliveira, T, Malit, J.J.L, Kokhanovska, A, Schleper, C, Pilhofer, M. | | Deposit date: | 2024-05-02 | | Release date: | 2025-04-02 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Microtubules in Asgard archaea.
Cell, 188, 2025
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9F6V
 | | cryoEM structure of Asgard tubulin heterodimer AtubA/B2 with GTP | | Descriptor: | Asgard tubulin A (AtubA) from Candidatus Lokiarchaeum ossiferum, Asgard tubulin B homolog (AtubB2) from Candidatus Lokiarchaeum ossiferum, GUANOSINE-5'-TRIPHOSPHATE | | Authors: | Wollweber, F, Xu, J, Ponce-Toled, R.I, Rodrigues-Oliveira, T, Malit, J.J.L, Kokhanovska, A, Schleper, C, Pilhofer, M. | | Deposit date: | 2024-05-02 | | Release date: | 2025-04-02 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Microtubules in Asgard archaea.
Cell, 188, 2025
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9HXC
 | | CryoEM structure of Asgard AtubA/B2 microtubule | | Descriptor: | Asgard tubulin AtubA with residues from TEV protease cleavage site, Asgard tubulin AtubB2, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Wollweber, F, Xu, J, Ponce-Toledo, R.I, Rodrigues-Oliveira, T, Malit, J.J.L, Kokhanovska, A, Wieczorek, M, Schleper, C, Pilhofer, M. | | Deposit date: | 2025-01-07 | | Release date: | 2025-04-02 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Microtubules in Asgard archaea.
Cell, 188, 2025
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7ADZ
 | | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the cap portion in extended state. | | Descriptor: | Phage tail protein, Putative phage tail sheath protein FI, cap adaptor protein (Algo2), ... | | Authors: | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | | Deposit date: | 2020-09-17 | | Release date: | 2022-02-16 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis.
Nat Microbiol, 7, 2022
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7AEK
 | | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the contracted sheath shell. | | Descriptor: | Putative phage tail sheath protein FI | | Authors: | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | | Deposit date: | 2020-09-17 | | Release date: | 2022-02-16 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis.
Nat Microbiol, 7, 2022
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7AEB
 | | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the baseplate complex in extended state applied 6-fold symmetry. | | Descriptor: | Baseplate_J domain-containing protein, LysM domain-containing protein, Phage tail protein, ... | | Authors: | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | | Deposit date: | 2020-09-17 | | Release date: | 2022-02-16 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis.
Nat Microbiol, 7, 2022
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7AE0
 | | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the sheath-tube module in extended state. | | Descriptor: | Phage tail protein, Putative phage tail sheath protein FI | | Authors: | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | | Deposit date: | 2020-09-17 | | Release date: | 2022-02-16 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis.
Nat Microbiol, 7, 2022
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7AEF
 | | Cryo-EM structure of an extracellular contractile injection system in marine bacterium Algoriphagus machipongonensis, the baseplate complex in extended state applied 3-fold symmetry. | | Descriptor: | Baseplate_J domain-containing protein, LysM domain-containing protein, Phage tail protein, ... | | Authors: | Xu, J, Ericson, C, Feldmueller, M, Lien, Y.W, Pilhofer, M. | | Deposit date: | 2020-09-17 | | Release date: | 2022-02-23 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Identification and structure of an extracellular contractile injection system from the marine bacterium Algoriphagus machipongonensis.
Nat Microbiol, 7, 2022
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9EZM
 | | CryoEM structure of the contracted sheath in H. borinquense | | Descriptor: | Phage tail sheath protein FI | | Authors: | Zachs, T, Malit, J.J, Xu, J, Schuerch, A, Sivabalasarma, S, Nussbaum, P, Albers, S.V, Pilhofer, M. | | Deposit date: | 2024-04-12 | | Release date: | 2024-11-27 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Archaeal type six secretion system mediates contact-dependent antagonism.
Sci Adv, 10, 2024
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