4R4P
 
 | | Crystal Structure of the VS ribozyme-A756G mutant | | 分子名称: | MAGNESIUM ION, VS ribozyme RNA | | 著者 | Piccirilli, J.A, Suslov, N.B, Dasgupta, S, Huang, H, Lilley, D.M.J, Rice, P.A. | | 登録日 | 2014-08-19 | | 公開日 | 2015-09-30 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | Crystal structure of the Varkud satellite ribozyme.
Nat.Chem.Biol., 11, 2015
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4R4V
 | | Crystal structure of the VS ribozyme - G638A mutant | | 分子名称: | MAGNESIUM ION, POTASSIUM ION, VS ribozyme RNA | | 著者 | Piccirilli, J.A, Suslov, N.B, Dasgupta, S, Huang, H, Lilley, D.M.J, Rice, P.A. | | 登録日 | 2014-08-19 | | 公開日 | 2015-09-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | Crystal structure of the Varkud satellite ribozyme.
Nat.Chem.Biol., 11, 2015
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9AUR
 | | Crystal structure of loop-closed A21 2'-OMe dumbbell RNA bridged by glycine | | 分子名称: | Fab BL3-6 heavy chain, Fab BL3-6 light chain, GLYCINE, ... | | 著者 | Radakovic, A, Lewicka, A, Todisco, M, Aitken, H.R.M, Weiss, Z, Kim, S, Bannan, A, Piccirilli, J.A, Szostak, J.W. | | 登録日 | 2024-02-29 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | A potential role for RNA aminoacylation prior to its role in peptide synthesis.
Proc.Natl.Acad.Sci.USA, 121, 2024
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9AUS
 | | Crystal structure of loop-closed dumbbell RNA bridged by glycine | | 分子名称: | Fab BL3-6 heavy chain, Fab BL3-6 light chain, GLYCINE, ... | | 著者 | Radakovic, A, Lewicka, A, Todisco, M, Aitken, H.R.M, Weiss, Z, Kim, S, Bannan, A, Piccirilli, J.A, Szostak, J.W. | | 登録日 | 2024-02-29 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | A potential role for RNA aminoacylation prior to its role in peptide synthesis.
Proc.Natl.Acad.Sci.USA, 121, 2024
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6U8K
 | | Crystal structure of hepatitis C virus IRES junction IIIabc in complex with Fab HCV3 | | 分子名称: | Heavy chain of Fab HCV3, JIIIabc RNA (68-MER), Light chain of Fab HCV3 | | 著者 | Koirala, D, Lewicka, A, Koldobskaya, Y, Huang, H, Piccirilli, J.A. | | 登録日 | 2019-09-05 | | 公開日 | 2019-12-04 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Synthetic Antibody Binding to a Preorganized RNA Domain of Hepatitis C Virus Internal Ribosome Entry Site Inhibits Translation.
Acs Chem.Biol., 15, 2020
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6B14
 | | Crystal structure of Spinach RNA aptamer in complex with Fab BL3-6S97N | | 分子名称: | Heavy chain of Fab BL3-6S97N, Light chain of Fab BL3-6S97N, MAGNESIUM ION, ... | | 著者 | DasGupta, S, Shelke, S.A, Piccirilli, J.A. | | 登録日 | 2017-09-16 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Affinity maturation of a portable Fab-RNA module for chaperone-assisted RNA crystallography.
Nucleic Acids Res., 46, 2018
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8SH5
 | | Crystal structure of 3'cap-independent translation enhancers (CITE) from Pea enation mosaic virus RNA 2 (PEMV2) with Fab BL3-6K170A | | 分子名称: | Fab BL3-6K170A heavy chain, Fab BL3-6K170A light chain, RNA (88-MER) | | 著者 | Lewicka, A, Roman, C, Rice, P.A, Piccirilli, J.A. | | 登録日 | 2023-04-13 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal structure of a cap-independent translation enhancer RNA.
Nucleic Acids Res., 51, 2023
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7U0Y
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3IVK
 | | Crystal Structure of the Catalytic Core of an RNA Polymerase Ribozyme Complexed with an Antigen Binding Antibody Fragment | | 分子名称: | CADMIUM ION, CHLORIDE ION, Fab heavy chain, ... | | 著者 | Koldobskaya, Y, Duguid, E.M, Shechner, D.M, Koide, S, Kossiakoff, A.A, Bartel, D.P, Piccirilli, J.A. | | 登録日 | 2009-09-01 | | 公開日 | 2010-03-02 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal structure of the catalytic core of an RNA-polymerase ribozyme.
Science, 326, 2009
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8UTA
 | | yjdF riboswitch from R. gauvreauii in complex with proflavine bound to Fab BL3-6 S97N | | 分子名称: | Fab BL3-6 S97N heavy chain, Fab BL3-6 S97N light chain, MAGNESIUM ION, ... | | 著者 | Krochmal, D, Lewicka, A, Piccirilli, J.A. | | 登録日 | 2023-10-30 | | 公開日 | 2024-04-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structural basis for promiscuity in ligand recognition by yjdF riboswitch.
Cell Discov, 10, 2024
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8UIW
 | | yjdF riboswitch from R. gauvreauii in complex with chelerythrine bound to Fab BL3-6 S97N | | 分子名称: | 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium, Fab BL3-6 S97N heavy chain, Fab BL3-6 S97N light chain, ... | | 著者 | Krochmal, D, Lewicka, A, Piccirilli, J.A. | | 登録日 | 2023-10-10 | | 公開日 | 2024-04-10 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Structural basis for promiscuity in ligand recognition by yjdF riboswitch.
Cell Discov, 10, 2024
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6U8D
 | | Crystal structure of hepatitis C virus IRES junction IIIabc in complex with Fab HCV2 | | 分子名称: | Heavy chain of Fab HCV2, JIIIabc RNA (68-MER), Light chain of Fab HCV2 | | 著者 | Koirala, D, Lewicka, A, Koldobskaya, Y, Huang, H, Piccirilli, J.A. | | 登録日 | 2019-09-04 | | 公開日 | 2019-12-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.807 Å) | | 主引用文献 | Synthetic Antibody Binding to a Preorganized RNA Domain of Hepatitis C Virus Internal Ribosome Entry Site Inhibits Translation.
Acs Chem.Biol., 15, 2020
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7SZU
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2R8S
 | | High resolution structure of a specific synthetic FAB bound to P4-P6 RNA ribozyme domain | | 分子名称: | Fab heavy chain, Fab light chain, MAGNESIUM ION, ... | | 著者 | Ye, J.D, Tereshko, V, Sidhu, S.S, Koide, S, Kossiakoff, A.A, Piccirilli, J.A. | | 登録日 | 2007-09-11 | | 公開日 | 2007-12-04 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Synthetic antibodies for specific recognition and crystallization of structured RNA
Proc.Natl.Acad.Sci.Usa, 105, 2008
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6XJQ
 | | Crystal structure of a self-alkylating ribozyme - alkylated form with biotinylated epoxide substrate | | 分子名称: | 2-{[(4R)-4-hydroxyhexyl]oxy}ethyl 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate, Fab HAVx Heavy Chain, Fab HAVx Light Chain, ... | | 著者 | Koirala, D, Piccirilli, J.A. | | 登録日 | 2020-06-24 | | 公開日 | 2022-01-19 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.708 Å) | | 主引用文献 | Structural basis for substrate binding and catalysis by a self-alkylating ribozyme.
Nat.Chem.Biol., 18, 2022
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6XJW
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5V3I
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2KZZ
 | | KLENOW FRAGMENT WITH NORMAL SUBSTRATE AND ZINC ONLY | | 分子名称: | DNA (5'-D(*GP*CP*TP*T*AP*CP*G)-3'), PROTEIN (DNA POLYMERASE I), ZINC ION | | 著者 | Brautigam, C.A, Sun, S, Piccirilli, J.A, Steitz, T.A. | | 登録日 | 1998-07-07 | | 公開日 | 1999-12-14 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli.
Biochemistry, 38, 1999
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2KZM
 | | KLENOW FRAGMENT WITH NORMAL SUBSTRATE AND ZINC AND MANGANESE | | 分子名称: | DNA (5'-D(*GP*CP*TP*TP*A*CP*GP*C)-3'), MANGANESE (II) ION, PROTEIN (DNA POLYMERASE I), ... | | 著者 | Brautigam, C.A, Sun, S, Piccirilli, J.A, Steitz, T.A. | | 登録日 | 1998-07-03 | | 公開日 | 1999-02-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli.
Biochemistry, 38, 1999
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6MWN
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6XJY
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6XJZ
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2KFZ
 | | KLENOW FRAGMENT WITH BRIDGING-SULFUR SUBSTRATE AND ZINC ONLY | | 分子名称: | 5'-D(*GP*CP*TP*TP*AP*(US1)P*G)-3', KLENOW FRAGMENT OF DNA POLYMERASE I, MAGNESIUM ION, ... | | 著者 | Brautigam, C.A, Sun, S, Piccirilli, J.A, Steitz, T.A. | | 登録日 | 1998-07-02 | | 公開日 | 1998-11-11 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli.
Biochemistry, 38, 1999
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2KFN
 | | KLENOW FRAGMENT WITH BRIDGING-SULFUR SUBSTRATE AND MANGANESE | | 分子名称: | 5'-D(*GP*CP*TP*TP*AP*(US1)P*G)-3', KLENOW FRAGMENT OF DNA POLYMERASE I, MAGNESIUM ION, ... | | 著者 | Brautigam, C.A, Sun, S, Piccirilli, J.A, Steitz, T.A. | | 登録日 | 1998-07-01 | | 公開日 | 1998-11-11 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli.
Biochemistry, 38, 1999
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3OV6
 | | CD1c in complex with MPM (mannosyl-beta1-phosphomycoketide) | | 分子名称: | 1-O-[(S)-hydroxy{[(4S,8S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl]oxy}phosphoryl]-beta-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | | 著者 | Scharf, L, Li, N.S, Hawk, A.J, Garzon, D, Zhang, T, Kazen, A.R, Shah, S, Haddadian, E.J, Saghatelian, A, Faraldo-Gomez, J.D, Meredith, S.C, Piccirilli, J.A, Adams, E.J. | | 登録日 | 2010-09-15 | | 公開日 | 2011-01-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | | 主引用文献 | The 2.5 A structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation
Immunity, 33, 2010
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