2PYR
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![BU of 2pyr by Molmil](/molmil-images/mine/2pyr) | PHOTOACTIVE YELLOW PROTEIN, 1 NANOSECOND INTERMEDIATE (287K) | Descriptor: | 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN | Authors: | Perman, B, Srajer, V, Ren, Z, Teng, T.Y, Pradervand, C, Ursby, T, Bourgeois, D, Schotte, F, Wulff, M, Kort, R, Hellingwerf, K, Moffat, K. | Deposit date: | 1998-03-04 | Release date: | 1999-04-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Energy transduction on the nanosecond time scale: early structural events in a xanthopsin photocycle. Science, 279, 1998
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2ORZ
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![BU of 2orz by Molmil](/molmil-images/mine/2orz) | Structural Basis for Ligand Binding and Heparin Mediated Activation of Neuropilin | Descriptor: | Neuropilin-1, Tuftsin | Authors: | Vander Kooi, C.W, Jusino, M.A, Perman, B, Neau, D.B, Bellamy, H.D, Leahy, D.J. | Deposit date: | 2007-02-05 | Release date: | 2007-04-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural basis for ligand and heparin binding to neuropilin B domains. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2ORX
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![BU of 2orx by Molmil](/molmil-images/mine/2orx) | Structural Basis for Ligand Binding and Heparin Mediated Activation of Neuropilin | Descriptor: | Neuropilin-1 | Authors: | Vander Kooi, C.W, Jusino, M.A, Perman, B, Neau, D.B, Bellamy, H.D, Leahy, D.J. | Deposit date: | 2007-02-05 | Release date: | 2007-04-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for ligand and heparin binding to neuropilin B domains Proc.Natl.Acad.Sci.Usa, 104, 2007
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1YN3
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![BU of 1yn3 by Molmil](/molmil-images/mine/1yn3) | Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens | Descriptor: | truncated cell surface protein map-w | Authors: | Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J. | Deposit date: | 2005-01-23 | Release date: | 2005-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens. J.Biol.Chem., 280, 2005
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1YN4
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![BU of 1yn4 by Molmil](/molmil-images/mine/1yn4) | Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens | Descriptor: | EapH1, ZINC ION | Authors: | Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J. | Deposit date: | 2005-01-23 | Release date: | 2005-03-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens. J.Biol.Chem., 280, 2005
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1YN5
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![BU of 1yn5 by Molmil](/molmil-images/mine/1yn5) | Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens | Descriptor: | EapH2 | Authors: | Geisbrecht, B.V, Hamaoka, B.Y, Perman, B, Zemla, A, Leahy, D.J. | Deposit date: | 2005-01-23 | Release date: | 2005-03-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Crystal Structures of EAP Domains from Staphylococcus aureus Reveal an Unexpected Homology to Bacterial Superantigens. J.Biol.Chem., 280, 2005
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8PRK
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![BU of 8prk by Molmil](/molmil-images/mine/8prk) | THE R78K AND D117E ACTIVE SITE VARIANTS OF SACCHAROMYCES CEREVISIAE SOLUBLE INORGANIC PYROPHOSPHATASE: STRUCTURAL STUDIES AND MECHANISTIC IMPLICATIONS | Descriptor: | MANGANESE (II) ION, PHOSPHATE ION, PROTEIN (INORGANIC PYROPHOSPHATASE) | Authors: | Tuominen, V, Heikinheimo, P, Kajander, T, Torkkel, T, Hyytia, T, Kapyla, J, Lahti, R, Cooperman, B.S, Goldman, A. | Deposit date: | 1998-09-16 | Release date: | 1998-12-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The R78K and D117E active-site variants of Saccharomyces cerevisiae soluble inorganic pyrophosphatase: structural studies and mechanistic implications. J.Mol.Biol., 284, 1998
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1E9G
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![BU of 1e9g by Molmil](/molmil-images/mine/1e9g) | STRUCTURE OF INORGANIC PYROPHOSPHATASE | Descriptor: | INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, PHOSPHATE ION | Authors: | Heikinheimo, P, Tuominen, V, Ahonen, A.-K, Teplyakov, A, Cooperman, B.S, Baykov, A.A, Lahti, R, Goldman, A. | Deposit date: | 2000-10-12 | Release date: | 2001-03-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Toward a Quantum-Mechanical Description of Metal-Assisted Phosphoryl Transfer in Pyrophosphatase Proc.Natl.Acad.Sci.USA, 98, 2001
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117E
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![BU of 117e by Molmil](/molmil-images/mine/117e) | THE R78K AND D117E ACTIVE SITE VARIANTS OF SACCHAROMYCES CEREVISIAE SOLUBLE INORGANIC PYROPHOSPHATASE: STRUCTURAL STUDIES AND MECHANISTIC IMPLICATIONS | Descriptor: | MANGANESE (II) ION, PHOSPHATE ION, PROTEIN (INORGANIC PYROPHOSPHATASE) | Authors: | Tuominen, V, Heikinheimo, P, Kajander, T, Torkkel, T, Hyytia, T, Kapyla, J, Lahti, R, Cooperman, B.S, Goldman, A. | Deposit date: | 1998-09-15 | Release date: | 1998-12-23 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The R78K and D117E active-site variants of Saccharomyces cerevisiae soluble inorganic pyrophosphatase: structural studies and mechanistic implications. J.Mol.Biol., 284, 1998
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1HUJ
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![BU of 1huj by Molmil](/molmil-images/mine/1huj) | |
1E6A
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![BU of 1e6a by Molmil](/molmil-images/mine/1e6a) | Fluoride-inhibited substrate complex of Saccharomyces cerevisiae inorganic pyrophosphatase | Descriptor: | FLUORIDE ION, INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, ... | Authors: | Heikinheimo, P, Tuominen, V, Ahonen, A.-K, Teplyakov, A, Cooperman, B.S, Baykov, A.A, Lahti, R, Goldman, A. | Deposit date: | 2000-08-09 | Release date: | 2001-03-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Toward a quantum-mechanical description of metal-assisted phosphoryl transfer in pyrophosphatase. Proc. Natl. Acad. Sci. U.S.A., 98, 2001
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1FOZ
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![BU of 1foz by Molmil](/molmil-images/mine/1foz) | STRUCTURE OF CYCLIC PEPTIDE INHIBITORS OF MAMMALIAN RIBONUCLEOTIDE REDUCTASE | Descriptor: | SYNTHETIC CYCLIC PEPTIDE | Authors: | Pellegrini, M, Liehr, S, Fisher, A.L, Cooperman, B.S, Mierke, D.F. | Deposit date: | 2000-08-29 | Release date: | 2000-11-22 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Structure-based optimization of peptide inhibitors of mammalian ribonucleotide reductase. Biochemistry, 39, 2000
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1AFT
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![BU of 1aft by Molmil](/molmil-images/mine/1aft) | SMALL SUBUNIT C-TERMINAL INHIBITORY PEPTIDE OF MOUSE RIBONUCLEOTIDE REDUCTASE AS BOUND TO THE LARGE SUBUNIT, NMR, 26 STRUCTURES | Descriptor: | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE | Authors: | Laub, P.B, Fisher, A.L, Furst, G.T, Barwis, B.A, Hamann, C.S, Cooperman, B.S. | Deposit date: | 1997-03-13 | Release date: | 1997-05-15 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | NMR structure of an inhibitory R2 C-terminal peptide bound to mouse ribonucleotide reductase R1 subunit. Nat.Struct.Biol., 2, 1995
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1HUK
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2ZLF
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![BU of 2zlf by Molmil](/molmil-images/mine/2zlf) | The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase | Descriptor: | FTLDADF, Ribonucleoside-diphosphate reductase large chain 1 | Authors: | Xu, H, Fairman, J.W, Wijerathna, S.R, LaMacchia, J, Kreischer, N.R, Helmbrecht, E, Cooperman, B.S, Dealwis, C. | Deposit date: | 2008-04-09 | Release date: | 2008-08-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore J.Med.Chem., 51, 2008
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2ZLG
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![BU of 2zlg by Molmil](/molmil-images/mine/2zlg) | The Structual Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase | Descriptor: | (5R,9S,12S,15S,18S,21S)-21-benzyl-12,18-bis(carboxymethyl)-15-cyclohexyl-1-(9H-fluoren-9-yl)-4-methyl-9-(2-methylpropyl)-3,6,10,13,16,19-hexaoxo-5-phenyl-2-oxa-4,8,11,14,17,20-hexaazadocosan-22-oic acid, GLYCEROL, Ribonucleoside-diphosphate reductase large chain 1 | Authors: | Xu, H, Fairman, J.W, Wijerathna, S.R, LaMacchia, J, Kreischer, N.R, Helmbrecht, E, Cooperman, B.S, Dealwis, C. | Deposit date: | 2008-04-09 | Release date: | 2008-08-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.52 Å) | Cite: | The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore J.Med.Chem., 51, 2008
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