1AFT

SMALL SUBUNIT C-TERMINAL INHIBITORY PEPTIDE OF MOUSE RIBONUCLEOTIDE REDUCTASE AS BOUND TO THE LARGE SUBUNIT, NMR, 26 STRUCTURES

Summary for 1AFT

Entry DOI	10.2210/pdb1aft/pdb
Descriptor	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (1 entity in total)
Functional Keywords	ribonucleotide reductase, peptide inhibitors, transferred noesy, restrained molecular dynamics, nonstandard type i turn
Cellular location	Cytoplasm: P11157
Total number of polymer chains	1
Total formula weight	853.92
Authors	Laub, P.B.,Fisher, A.L.,Furst, G.T.,Barwis, B.A.,Hamann, C.S.,Cooperman, B.S. (deposition date: 1997-03-13, release date: 1997-05-15, Last modification date: 2024-10-30)
Primary citation	Fisher, A.,Laub, P.B.,Cooperman, B.S. NMR structure of an inhibitory R2 C-terminal peptide bound to mouse ribonucleotide reductase R1 subunit. Nat.Struct.Biol., 2:951-955, 1995 Cited by PubMed Abstract: The structure of peptide N-AcYTLDADF when bound to the large subunit of mouse ribonucleotide reductase has been elucidated by transfer NOE. This structure suggests a general design for type 1 RR inhibitors. PubMed: 7583667 DOI: 10.1038/nsb1195-951 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation