1DC1
 
 | | RESTRICTION ENZYME BSOBI/DNA COMPLEX STRUCTURE: ENCIRCLEMENT OF THE DNA AND HISTIDINE-CATALYZED HYDROLYSIS WITHIN A CANONICAL RESTRICTION ENZYME FOLD | | Descriptor: | 1,4-DIETHYLENE DIOXIDE, BSOBI RESTRICTION ENDONUCLEASE, DNA (5'-D(*T*AP*TP*AP*CP*TP*CP*GP*AP*GP*TP*AP*T)-3') | | Authors: | van der Woerd, M.J, Pelletier, J.J, Xu, S.-Y, Friedman, A.M. | | Deposit date: | 1999-11-04 | | Release date: | 2001-02-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Restriction enzyme BsoBI-DNA complex: a tunnel for recognition of degenerate DNA sequences and potential histidine catalysis.
Structure, 9, 2001
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6XKI
 | | Crystal structure of eIF4A-I in complex with RNA bound to des-MePateA, a pateamine A analog | | Descriptor: | (3S,6Z,8E,11S,15R)-15-amino-3-[(1E,3E,5E)-7-(dimethylamino)-2,5-dimethylhepta-1,3,5-trien-1-yl]-9,11-dimethyl-4,12-dioxa-20-thia-21-azabicyclo[16.2.1]henicosa-1(21),6,8,18-tetraene-5,13-dione, Eukaryotic initiation factor 4A-I, MAGNESIUM ION, ... | | Authors: | Liang, J, Naineni, S.K, Pelletier, J, Nagar, B. | | Deposit date: | 2020-06-26 | | Release date: | 2021-01-06 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.87 Å) | | Cite: | Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A.
Cell Chem Biol, 28, 2021
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5TBW
 | | Crystal structure of chlorolissoclimide bound to the yeast 80S ribosome | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | | Authors: | Konst, Z.A, Szklarski, A.R, Pellegrino, S, Michalak, S.E, Meyer, M, Zanette, C, Cencic, R, Nam, S, Horne, D.A, Pelletier, J, Mobley, D.L, Yusupova, G, Yusupov, M, Vanderwal, C.D. | | Deposit date: | 2016-09-13 | | Release date: | 2017-07-26 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides.
Nat Chem, 9, 2017
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4MEZ
 | | Crystal structure of M68L/M69T double mutant TEM-1 | | Descriptor: | Beta-lactamase TEM, CHLORIDE ION, GLYCEROL, ... | | Authors: | Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M. | | Deposit date: | 2013-08-27 | | Release date: | 2014-10-15 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.047 Å) | | Cite: | The Structural Dynamics of Engineered beta-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function.
Sci Rep, 9, 2019
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1LTQ
 | | CRYSTAL STRUCTURE OF T4 POLYNUCLEOTIDE KINASE | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, POLYNUCLEOTIDE KINASE | | Authors: | Galburt, E.A, Pelletier, J, Wilson, G, Stoddard, B.L. | | Deposit date: | 2002-05-20 | | Release date: | 2002-10-09 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Structure of a tRNA repair enzyme and molecular biology workhorse: T4 polynucleotide kinase.
Structure, 10, 2002
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4ID4
 | | Crystal structure of chimeric beta-lactamase cTEM-17m | | Descriptor: | Beta-lactamase TEM, Beta-lactamase PSE-4, CHLORIDE ION, ... | | Authors: | Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M. | | Deposit date: | 2012-12-11 | | Release date: | 2013-12-25 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | Maintenance of Native-like Protein Dynamics May Not Be Required for Engineering Functional Proteins.
Chem.Biol., 21, 2014
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4QY6
 | | Crystal structures of chimeric beta-lactamase cTEM-19m showing different conformations | | Descriptor: | Beta-lactamase TEM, Beta-lactamase PSE-4, CHLORIDE ION, ... | | Authors: | Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M. | | Deposit date: | 2014-07-23 | | Release date: | 2015-08-12 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Crystal structures of chimeric beta-lactamase cTEM-19m showing different conformations
To be Published
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4R4R
 | | Crystal structure of chimeric beta-lactamase cTEM-19m at 1.2 angstrom resolution | | Descriptor: | Beta-lactamase TEM,Beta-lactamase PSE-4, CHLORIDE ION, MAGNESIUM ION | | Authors: | Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M. | | Deposit date: | 2014-08-19 | | Release date: | 2015-11-11 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | The Structural Dynamics of Engineered beta-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function.
Sci Rep, 9, 2019
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4R4S
 | | Crystal structure of chimeric beta-lactamase cTEM-19m at 1.1 angstrom resolution | | Descriptor: | Beta-lactamase TEM,Beta-lactamase PSE-4, CHLORIDE ION, MAGNESIUM ION | | Authors: | Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M. | | Deposit date: | 2014-08-19 | | Release date: | 2015-11-11 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | The Structural Dynamics of Engineered beta-Lactamases Vary Broadly on Three Timescales yet Sustain Native Function.
Sci Rep, 9, 2019
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4QY5
 | | Crystal structures of chimeric beta-lactamase cTEM-19m showing different conformations | | Descriptor: | Beta-lactamase TEM,Beta-lactamase PSE-4, CHLORIDE ION, MAGNESIUM ION | | Authors: | Park, J, Gobeil, S, Pelletier, J.N, Berghuis, A.M. | | Deposit date: | 2014-07-23 | | Release date: | 2015-08-12 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (1.501 Å) | | Cite: | Crystal structures of chimeric beta-lactamase cTEM-19m showing different conformations
To be Published
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1RC8
 | | T4 Polynucleotide Kinase bound to 5'-GTCAC-3' ssDNA | | Descriptor: | 5'-D(*GP*TP*CP*AP*C)-3', ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | | Authors: | Eastberg, J.H, Pelletier, J, Stoddard, B.L. | | Deposit date: | 2003-11-03 | | Release date: | 2004-02-17 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Recognition of DNA substrates by T4 bacteriophage polynucleotide kinase.
Nucleic Acids Res., 32, 2004
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1RPZ
 | | T4 POLYNUCLEOTIDE KINASE BOUND TO 5'-TGCAC-3' SSDNA | | Descriptor: | 5'-D(*TP*GP*CP*AP*C)-3', ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | | Authors: | Eastberg, J.H, Pelletier, J, Stoddard, B.L. | | Deposit date: | 2003-12-03 | | Release date: | 2004-02-17 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Recognition of DNA substrates by T4 bacteriophage polynucleotide kinase.
Nucleic Acids Res., 32, 2004
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1RRC
 | | T4 POLYNUCLEOTIDE KINASE BOUND TO 5'-GTC-3' SSDNA | | Descriptor: | 5'-D(*GP*TP*C)-3', ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | | Authors: | Eastberg, J.H, Pelletier, J, Stoddard, B.L. | | Deposit date: | 2003-12-08 | | Release date: | 2004-02-17 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.46 Å) | | Cite: | Recognition of DNA substrates by T4 bacteriophage polynucleotide kinase.
Nucleic Acids Res., 32, 2004
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9AVR
 | | Human eIF4A-1 in complex with AMP-PNP, RNA, and the inhibitor silvestrol | | Descriptor: | Eukaryotic initiation factor 4A-I, IODIDE ION, MAGNESIUM ION, ... | | Authors: | Bhatt, G.B, Naineni, S.K, Cencic, R.C, Jiramongkolsiri, E.J, Huang, S.H, Pelletier, J.P, Nagar, B.N. | | Deposit date: | 2024-03-04 | | Release date: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Human eIF4A-1 in complex with AMP-PNP, RNA, and the inhibitor silvestrol
To Be Published
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