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PDB: 54 件
1SRS
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BU of 1srs by Molmil
SERUM RESPONSE FACTOR (SRF) CORE COMPLEXED WITH SPECIFIC SRE DNA
分子名称: DNA (5'-D(*CP*CP*(5IU)P*TP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*CP*CP*AP*TP*G)-3'), DNA (5'-D(*CP*CP*AP*TP*GP*GP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*A P*AP*G)-3'), PROTEIN (SERUM RESPONSE FACTOR (SRF))
著者Pellegrini, L, Tan, S, Richmond, T.J.
登録日1995-07-28
公開日1995-07-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of serum response factor core bound to DNA.
Nature, 376, 1995
1E0O
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BU of 1e0o by Molmil
CRYSTAL STRUCTURE OF A TERNARY FGF1-FGFR2-HEPARIN COMPLEX
分子名称: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, FIBROBLAST GROWTH FACTOR 1, FIBROBLAST GROWTH FACTOR RECEPTOR 2, ...
著者Pellegrini, L, Burke, D.F, von Delft, F, Mulloy, B, Blundell, T.L.
登録日2000-04-03
公開日2000-10-23
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Fibroblast Growth Factor Receptor Ectodomain Bound to Ligand and Heparin
Nature, 407, 2000
1N0W
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BU of 1n0w by Molmil
Crystal structure of a RAD51-BRCA2 BRC repeat complex
分子名称: 1,2-ETHANEDIOL, ARTIFICIAL GLY-SER-MSE-GLY PEPTIDE, Breast cancer type 2 susceptibility protein, ...
著者Pellegrini, L, Yu, D.S, Lo, T, Anand, S, Lee, M, Blundell, T.L, Venkitaraman, A.R.
登録日2002-10-15
公開日2002-11-27
最終更新日2020-01-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Insights into DNA recombination from the structure of a RAD51-BRCA2 complex
Nature, 420, 2002
2ILR
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BU of 2ilr by Molmil
Crystal structure of human Fanconi Anemia protein E C-terminal domain
分子名称: Fanconi anemia group E protein
著者Pellegrini, L, Nookala, R.K.
登録日2006-10-03
公開日2007-02-27
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Insights into Fanconi Anaemia from the structure of human FANCE
Nucleic Acids Res., 35, 2007
6T9Q
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BU of 6t9q by Molmil
Crystal structure of the second, C-terminal repeat of the DNA-binding domain of human TImeless
分子名称: Protein timeless homolog
著者Pellegrini, L, Holzer, S.
登録日2019-10-28
公開日2020-07-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Timeless couples G-quadruplex detection with processing by DDX11 helicase during DNA replication.
Embo J., 39, 2020
5NWL
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BU of 5nwl by Molmil
Crystal structure of a human RAD51-ATP filament.
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA repair protein RAD51 homolog 1, MAGNESIUM ION
著者Pellegrini, L, Moschetti, T.
登録日2017-05-06
公開日2018-03-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.93 Å)
主引用文献Two distinct conformational states define the interaction of human RAD51-ATP with single-stranded DNA.
EMBO J., 37, 2018
5OF3
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BU of 5of3 by Molmil
Crystal structure of the heterotrimeric PriSLX primase from S. solfataricus.
分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA primase large subunit PriL, DNA primase small subunit PriS, ...
著者Pellegrini, L, Holzer, S.
登録日2017-07-10
公開日2017-11-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.906 Å)
主引用文献Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster.
Nat Commun, 8, 2017
5OFN
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BU of 5ofn by Molmil
Crystal structure of the heterotrimeric PriSLX primase from S. solfataricus.
分子名称: DNA primase large subunit PriL,PriL-X fusion protein, DNA primase small subunit PriS, ZINC ION
著者Pellegrini, L, Holzer, S.
登録日2017-07-11
公開日2017-11-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.005 Å)
主引用文献Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster.
Nat Commun, 8, 2017
5OGS
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BU of 5ogs by Molmil
Crystal structure of human AND-1 SepB domain
分子名称: MALONATE ION, WD repeat and HMG-box DNA-binding protein 1
著者Pellegrini, L, Simon, A.C.
登録日2017-07-13
公開日2017-11-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献The human CTF4-orthologue AND-1 interacts with DNA polymerase alpha /primase via its unique C-terminal HMG box.
Open Biol, 7, 2017
3LGB
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BU of 3lgb by Molmil
Crystal Structure of the Fe-S Domain of the yeast DNA primase
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA primase large subunit, GLYCEROL, ...
著者Sauguet, L, Pellegrini, L.
登録日2010-01-20
公開日2010-04-21
最終更新日2011-10-05
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Shared Active Site Architecture between the Large Subunit of Eukaryotic Primase and DNA Photolyase
PLOS ONE, 5, 2010
4FYD
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BU of 4fyd by Molmil
Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA and dGTP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*TP*GP*AP*GP*CP*GP*TP*G*TP*GP*TP*AP*CP*CP*CP*CP*TP*GP*CP*CP*CP*GP*CP*CP*G)-3'), DNA polymerase alpha catalytic subunit A, ...
著者Perera, R.L, Pellegrini, L.
登録日2012-07-04
公開日2013-02-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha
eLife, 2, 2013
4WWM
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BU of 4wwm by Molmil
X-ray crystal structure of Sulfolobus solfataricus Urm1
分子名称: SULFATE ION, Uncharacterized protein
著者Bray, S.M, Anjum, S.R, Blackwood, J.K, Kilkenny, M.L, Coelho, M.A, Foster, B.M, Pellegrini, L, Robinson, N.P.
登録日2014-11-11
公開日2015-09-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Involvement of a eukaryotic-like ubiquitin-related modifier in the proteasome pathway of the archaeon Sulfolobus acidocaldarius.
Nat Commun, 6, 2015
5HOI
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BU of 5hoi by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Tof2.
分子名称: DNA polymerase alpha-binding protein, Topoisomerase 1-associated factor 2
著者Simon, A.C, Pellegrini, L.
登録日2016-01-19
公開日2016-06-22
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase.
Mol.Cell, 63, 2016
5HOG
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BU of 5hog by Molmil
Crystal structure of the carboxy-terminal domain of yeast Ctf4 bound to Dna2.
分子名称: DNA polymerase alpha-binding protein, Dna2p
著者Simon, A.C, Pellegrini, L.
登録日2016-01-19
公開日2016-06-22
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.092 Å)
主引用文献Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase.
Mol.Cell, 63, 2016
7BGF
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BU of 7bgf by Molmil
CRYSTAL STRUCTURE OF THE N-TERMINAL DIMERIC COILED COIL OF THE HUMAN CTIP PROTEIN
分子名称: DNA endonuclease RBBP8,CtIP/RBBP8
著者Morton, C.R, Pellegrini, L.
登録日2021-01-07
公開日2021-06-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献Structural basis for the coiled-coil architecture of human CtIP.
Open Biology, 11, 2021
1IK9
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BU of 1ik9 by Molmil
CRYSTAL STRUCTURE OF A XRCC4-DNA LIGASE IV COMPLEX
分子名称: DNA LIGASE IV, DNA REPAIR PROTEIN XRCC4
著者Sibanda, B.L, Critchlow, S.E, Begun, J, Pei, X.Y, Jackson, S.P, Blundell, T.L, Pellegrini, L.
登録日2001-05-03
公開日2001-11-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of an Xrcc4-DNA ligase IV complex.
Nat.Struct.Biol., 8, 2001
3FLO
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BU of 3flo by Molmil
Crystal structure of the carboxyl-terminal domain of yeast DNA polymerase alpha in complex with its B subunit
分子名称: DNA polymerase alpha catalytic subunit A, DNA polymerase alpha subunit B, SULFATE ION, ...
著者Klinge, S.N, Pellegrini, L.
登録日2008-12-19
公開日2009-06-09
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献3D architecture of DNA Pol alpha reveals the functional core of multi-subunit replicative polymerases
Embo J., 28, 2009
4FVM
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BU of 4fvm by Molmil
Crystal structure of yeast DNA polymerase alpha
分子名称: DNA polymerase alpha catalytic subunit A
著者Perera, R.L, Pellegrini, L.
登録日2012-06-29
公開日2013-02-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha
eLife, 2, 2013
4FXD
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BU of 4fxd by Molmil
Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA
分子名称: DNA (5'-D(*TP*TP*TP*TP*CP*GP*CP*TP*GP*CP*CP*CP*GP*CP*CP*T)-3'), DNA polymerase alpha catalytic subunit A, RNA (5'-R(*AP*GP*GP*CP*GP*GP*GP*CP*AP*G)-3')
著者Perera, R.L, Torella, R, Klinge, S, Kilkenny, M.L, Maman, J.D, Pellegrini, L.
登録日2012-07-03
公開日2013-02-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha
eLife, 2, 2013
4B08
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BU of 4b08 by Molmil
Yeast DNA polymerase alpha, Selenomethionine protein
分子名称: DNA POLYMERASE ALPHA CATALYTIC SUBUNIT A
著者Perera, R.L, Torella, R, Klinge, S, Kilkenny, M.L, Maman, J.D, Pellegrini, L.
登録日2012-06-29
公開日2013-02-27
最終更新日2013-05-01
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Mechanism for Priming DNA Synthesis by Yeast DNA Polymerase Alpha
Elife, 2, 2013
8PBD
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BU of 8pbd by Molmil
RAD51 filament on dsDNA bound by the BRCA2 c-terminus
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Breast cancer type 2 susceptibility protein, CALCIUM ION, ...
著者Appleby, R, Pellegrini, L.
登録日2023-06-09
公開日2023-11-15
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Structural basis for stabilisation of the RAD51 nucleoprotein filament by BRCA2.
Nat Commun, 14, 2023
8PBC
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BU of 8pbc by Molmil
RAD51 filament on ssDNA bound by the BRCA2 c-terminus
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Breast cancer type 2 susceptibility protein, CALCIUM ION, ...
著者Appleby, R, Pellegrini, L.
登録日2023-06-09
公開日2023-11-15
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Structural basis for stabilisation of the RAD51 nucleoprotein filament by BRCA2.
Nat Commun, 14, 2023
1Z56
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BU of 1z56 by Molmil
Co-Crystal Structure of Lif1p-Lig4p
分子名称: DNA ligase IV, Ligase interacting factor 1
著者Dore, A.S, Furnham, N, Davies, O.R, Sibanda, B.L, Chirgadze, D.Y, Jackson, S.P, Pellegrini, L, Blundell, T.L.
登録日2005-03-17
公開日2006-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.92 Å)
主引用文献Structure of an Xrcc4-DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode.
DNA REPAIR, 5, 2006
8BSC
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BU of 8bsc by Molmil
CryoEM structure of the RAD51 nucleoprotein filament in the presence of ADP and Ca2+
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, DNA repair protein RAD51 homolog 1
著者Appleby, R, Bollschweiler, D, Pellegrini, L.
登録日2022-11-24
公開日2023-05-03
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献A metal ion-dependent mechanism of RAD51 nucleoprotein filament disassembly.
Iscience, 26, 2023
8BQ2
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BU of 8bq2 by Molmil
CryoEM structure of the pre-synaptic RAD51 nucleoprotein filament in the presence of ATP and Ca2+
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ...
著者Appleby, R, Bollschweiler, D, Pellegrini, L.
登録日2022-11-18
公開日2023-05-03
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献A metal ion-dependent mechanism of RAD51 nucleoprotein filament disassembly.
Iscience, 26, 2023

 

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