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PDB: 30 results

3EYH
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BU of 3eyh by Molmil
Crystal structures of JAK1 and JAK2 inhibitor complexes
Descriptor: 2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE, Tyrosine-protein kinase
Authors:Williams, N.K, Bamert, R.S, Patell, O, Wang, C, Walden, P.M, Fantino, E.
Deposit date:2008-10-20
Release date:2009-02-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.
J.Mol.Biol., 387, 2009
3EYG
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BU of 3eyg by Molmil
Crystal structures of JAK1 and JAK2 inhibitor complexes
Descriptor: 3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile, Tyrosine-protein kinase
Authors:Williams, N.K, Bamert, R.S, Patell, O, Wang, C, Walden, P.M, Fantino, E.
Deposit date:2008-10-20
Release date:2009-02-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.
J.Mol.Biol., 387, 2009
2OGV
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BU of 2ogv by Molmil
Crystal Structure of the Autoinhibited Human c-Fms Kinase Domain
Descriptor: Macrophage colony-stimulating factor 1 receptor precursor
Authors:Walter, M, Lucet, I.S, Patel, O, Broughton, S.E, Bamert, R, Williams, N.K, Fantino, E, Wilks, A.F, Rossjohn, J.
Deposit date:2007-01-09
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The 2.7 A crystal structure of the autoinhibited human c-Fms kinase domain.
J.Mol.Biol., 367, 2007
3FUP
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BU of 3fup by Molmil
Crystal structures of JAK1 and JAK2 inhibitor complexes
Descriptor: 3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile, Tyrosine-protein kinase JAK2
Authors:Williams, N.K, Bamert, R.S, Patel, O, Fantino, E, Rossjohn, J, Lucet, I.S.
Deposit date:2009-01-14
Release date:2009-02-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.
J.Mol.Biol., 387, 2009
3SDX
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BU of 3sdx by Molmil
Crystal structure of human autoreactive-Valpha24 NKT TCR in complex with CD1d-beta-galactosylceramide
Descriptor: Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, N-[(2S,3R)-1-(beta-D-galactopyranosyloxy)-3-hydroxyoctadec-4-en-2-yl]tetracosanamide, ...
Authors:Clarke, A.J, Patel, O, Rossjohn, J.
Deposit date:2011-06-09
Release date:2011-10-05
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Recognition of beta-linked self glycolipids mediated by natural killer T cell antigen receptors
Nat.Immunol., 12, 2011
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