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PDB: 30 件

3EYH
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BU of 3eyh by Molmil
Crystal structures of JAK1 and JAK2 inhibitor complexes
分子名称: 2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE, Tyrosine-protein kinase
著者Williams, N.K, Bamert, R.S, Patell, O, Wang, C, Walden, P.M, Fantino, E.
登録日2008-10-20
公開日2009-02-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.
J.Mol.Biol., 387, 2009
3EYG
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Crystal structures of JAK1 and JAK2 inhibitor complexes
分子名称: 3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile, Tyrosine-protein kinase
著者Williams, N.K, Bamert, R.S, Patell, O, Wang, C, Walden, P.M, Fantino, E.
登録日2008-10-20
公開日2009-02-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.
J.Mol.Biol., 387, 2009
2OGV
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Crystal Structure of the Autoinhibited Human c-Fms Kinase Domain
分子名称: Macrophage colony-stimulating factor 1 receptor precursor
著者Walter, M, Lucet, I.S, Patel, O, Broughton, S.E, Bamert, R, Williams, N.K, Fantino, E, Wilks, A.F, Rossjohn, J.
登録日2007-01-09
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The 2.7 A crystal structure of the autoinhibited human c-Fms kinase domain.
J.Mol.Biol., 367, 2007
3FUP
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BU of 3fup by Molmil
Crystal structures of JAK1 and JAK2 inhibitor complexes
分子名称: 3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile, Tyrosine-protein kinase JAK2
著者Williams, N.K, Bamert, R.S, Patel, O, Fantino, E, Rossjohn, J, Lucet, I.S.
登録日2009-01-14
公開日2009-02-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.
J.Mol.Biol., 387, 2009
3SDX
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BU of 3sdx by Molmil
Crystal structure of human autoreactive-Valpha24 NKT TCR in complex with CD1d-beta-galactosylceramide
分子名称: Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, N-[(2S,3R)-1-(beta-D-galactopyranosyloxy)-3-hydroxyoctadec-4-en-2-yl]tetracosanamide, ...
著者Clarke, A.J, Patel, O, Rossjohn, J.
登録日2011-06-09
公開日2011-10-05
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Recognition of beta-linked self glycolipids mediated by natural killer T cell antigen receptors
Nat.Immunol., 12, 2011
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