6J10
| Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly | Descriptor: | 6-cyclohexyl-4-methyl-1-oxidanyl-pyridin-2-one, Capsid protein | Authors: | Park, S, Jin, M.S, Cho, Y, Kang, J, Kim, S, Park, M, Park, H, Kim, J, Park, S, Hwang, J, Kim, Y, Kim, Y.J. | Deposit date: | 2018-12-27 | Release date: | 2019-04-17 | Last modified: | 2019-05-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly. Nat Commun, 10, 2019
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8SQF
| OXA-48 bound to inhibitor CDD-2725 | Descriptor: | (1M)-3'-(benzyloxy)-5-hydroxy[1,1'-biphenyl]-3,4'-dicarboxylic acid, BICARBONATE ION, Beta-lactamase | Authors: | Park, S, Judge, A, Fan, J, Sankaran, B, Prasad, B.V.V, Palzkill, T. | Deposit date: | 2023-05-04 | Release date: | 2024-01-03 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Exploiting the Carboxylate-Binding Pocket of beta-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library. J.Med.Chem., 67, 2024
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8SQG
| OXA-48 bound to inhibitor CDD-2801 | Descriptor: | (1M)-3'-(benzyloxy)-5-[2-(methylamino)-2-oxoethoxy][1,1'-biphenyl]-3,4'-dicarboxylic acid, BICARBONATE ION, Beta-lactamase | Authors: | Park, S, Judge, A, Fan, J, Sankaran, B, Palzkill, T. | Deposit date: | 2023-05-04 | Release date: | 2024-01-03 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Exploiting the Carboxylate-Binding Pocket of beta-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library. J.Med.Chem., 67, 2024
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8KCA
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4NJD
| Structure of p21-activated kinase 4 with a novel inhibitor KY-04031 | Descriptor: | N-(1H-indazol-5-yl)-N'-[2-(1H-indol-3-yl)ethyl]-6-methoxy-1,3,5-triazine-2,4-diamine, Serine/threonine-protein kinase PAK 4 | Authors: | Park, S. | Deposit date: | 2013-11-09 | Release date: | 2014-05-21 | Last modified: | 2022-08-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Discovery and the structural basis of a novel p21-activated kinase 4 inhibitor. Cancer Lett., 349, 2014
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6JLA
| Crystal structure of a mouse ependymin related protein | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Mammalian ependymin-related protein 1 | Authors: | Park, S. | Deposit date: | 2019-03-04 | Release date: | 2020-03-04 | Last modified: | 2020-09-16 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of three ependymin-related proteins suggest their function as a hydrophobic molecule binder. Iucrj, 6, 2019
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1L5Z
| CRYSTAL STRUCTURE OF THE E121K SUBSTITUTION OF THE RECEIVER DOMAIN OF SINORHIZOBIUM MELILOTI DCTD | Descriptor: | C4-DICARBOXYLATE TRANSPORT TRANSCRIPTIONAL REGULATORY PROTEIN DCTD, GLYCEROL, SULFATE ION | Authors: | Park, S, Meyer, M, Jones, A.D, Yennawar, H.P, Yennawar, N.H, Nixon, B.T. | Deposit date: | 2002-03-08 | Release date: | 2002-10-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Two-component signaling in the AAA + ATPase DctD: binding Mg2+ and BeF3- selects between alternate dimeric states of the receiver domain FASEB J., 16, 2002
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1L5Y
| CRYSTAL STRUCTURE OF MG2+ / BEF3-BOUND RECEIVER DOMAIN OF SINORHIZOBIUM MELILOTI DCTD | Descriptor: | BERYLLIUM DIFLUORIDE, BERYLLIUM TETRAFLUORIDE ION, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Park, S, Meyer, M, Jones, A.D, Yennawar, H.P, Yennawar, N.H, Nixon, B.T. | Deposit date: | 2002-03-08 | Release date: | 2002-10-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Two-component signaling in the AAA + ATPase DctD: binding Mg2+ and BeF3- selects between alternate dimeric states of the receiver domain FASEB J., 16, 2002
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4FVC
| HmoB structure with heme | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Putative uncharacterized protein yhgC | Authors: | Park, S. | Deposit date: | 2012-06-29 | Release date: | 2013-07-03 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of HmoB with Heme To be Published
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5U7G
| Crystal Structure of the Catalytic Core of CBP | Descriptor: | CREB-binding protein, ZINC ION | Authors: | Park, S, Stanfield, R.L, Martinez-Yamout, M.M, Dyson, H.J, Wilson, I.A, Wright, P.E. | Deposit date: | 2016-12-12 | Release date: | 2017-06-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.401 Å) | Cite: | Role of the CBP catalytic core in intramolecular SUMOylation and control of histone H3 acetylation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1OWA
| Solution Structural Studies on Human Erythrocyte Alpha Spectrin N Terminal Tetramerization Domain | Descriptor: | Spectrin alpha chain, erythrocyte | Authors: | Park, S, Caffrey, M.S, Johnson, M.E, Fung, L.W. | Deposit date: | 2003-03-28 | Release date: | 2004-03-30 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structural studies on human erythrocyte alpha-spectrin tetramerization site. J.Biol.Chem., 278, 2003
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2KNH
| The Solution structure of the eTAFH domain of AML1-ETO complexed with HEB peptide | Descriptor: | Protein CBFA2T1, Transcription factor 12 | Authors: | Park, S, Cierpicki, T, Tonelli, M, Bushweller, J.H. | Deposit date: | 2009-08-25 | Release date: | 2009-10-06 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity. Blood, 113, 2009
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2KYX
| Solution structure of the RRM domain of CYP33 | Descriptor: | Peptidyl-prolyl cis-trans isomerase E | Authors: | Park, S, Bushweller, J.H. | Deposit date: | 2010-06-09 | Release date: | 2010-08-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression . Biochemistry, 49, 2010
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2KYU
| The solution structure of the PHD3 finger of MLL | Descriptor: | Histone-lysine N-methyltransferase MLL, ZINC ION | Authors: | Park, S, Bushweller, J.H. | Deposit date: | 2010-06-08 | Release date: | 2010-08-25 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | The PHD3 domain of MLL acts as a CYP33-regulated switch between MLL-mediated activation and repression. Biochemistry, 49, 2010
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6LXX
| Frog EPDR1 with an Ir atom | Descriptor: | CALCIUM ION, CHLORIDE ION, Ependymin-related 1, ... | Authors: | Park, S, Park, J. | Deposit date: | 2020-02-12 | Release date: | 2021-02-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A Single Soaked Iridium (IV) Ion Observed in the Frog Ependymin-Related Protein. Bull.Korean Chem.Soc., 41, 2020
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1ZC1
| Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites | Descriptor: | Ubiquitin fusion degradation protein 1 | Authors: | Park, S, Isaacson, R, Kim, H.T, Silver, P.A, Wagner, G. | Deposit date: | 2005-04-10 | Release date: | 2005-07-26 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Ufd1 Exhibits the AAA-ATPase Fold with Two Distinct Ubiquitin Interaction Sites Structure, 13, 2005
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2B86
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6L9X
| Xenons in frog EPDR1 | Descriptor: | Ependymin-related 1, XENON | Authors: | Park, S. | Deposit date: | 2019-11-11 | Release date: | 2020-11-11 | Last modified: | 2021-05-26 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | De novo Phasing Xenons Observed in the Frog Ependymin-Related Protein Crystals, 10, 2020
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2JPX
| A18H Vpu TM structure in lipid bilayers | Descriptor: | Vpu protein | Authors: | Park, S, Opella, S.J. | Deposit date: | 2007-05-25 | Release date: | 2007-11-13 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | Conformational changes induced by a single amino acid substitution in the trans-membrane domain of Vpu: implications for HIV-1 susceptibility to channel blocking drugs Protein Sci., 16, 2007
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2KLV
| Membrane-bound structure of the Pf1 major coat protein in DHPC micelle | Descriptor: | Capsid protein G8P | Authors: | Park, S, Son, W, Mukhopadhyay, R, Valafar, H, Opella, S.J. | Deposit date: | 2009-07-08 | Release date: | 2009-10-06 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Phage-induced alignment of membrane proteins enables the measurement and structural analysis of residual dipolar couplings with dipolar waves and lambda-maps. J.Am.Chem.Soc., 131, 2009
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2KSJ
| Structure and Dynamics of the Membrane-bound form of Pf1 Coat Protein: Implications for Structural Rearrangement During Virus Assembly | Descriptor: | Capsid protein G8P | Authors: | Park, S, Marassi, F, Black, D, Opella, S.J. | Deposit date: | 2010-01-05 | Release date: | 2010-11-10 | Last modified: | 2024-05-01 | Method: | SOLID-STATE NMR, SOLUTION NMR | Cite: | Structure and dynamics of the membrane-bound form of Pf1 coat protein: implications of structural rearrangement for virus assembly. Biophys.J., 99, 2010
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2LNL
| Structure of human CXCR1 in phospholipid bilayers | Descriptor: | C-X-C chemokine receptor type 1 | Authors: | Park, S, Das, B.B, Casagrande, F, Nothnagel, H, Chu, M, Kiefer, H, Maier, K, De Angelis, A, Marassi, F.M, Opella, S.J. | Deposit date: | 2011-12-31 | Release date: | 2012-10-17 | Last modified: | 2016-04-27 | Method: | SOLID-STATE NMR | Cite: | Structure of the chemokine receptor CXCR1 in phospholipid bilayers. Nature, 491, 2012
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6AGQ
| Acetyl xylan esterase from Paenibacillus sp. R4 | Descriptor: | ZINC ION, acetyl xylan esterase | Authors: | Park, S, Lee, C.W, Lee, J.H. | Deposit date: | 2018-08-13 | Release date: | 2018-10-10 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure and functional characterization of a cold-active acetyl xylan esterase (PbAcE) from psychrophilic soil microbe Paenibacillus sp. PLoS ONE, 13, 2018
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1EHG
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1EHF
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