Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 16 件
1SOS
DownloadVisualize
BU of 1sos by Molmil
ATOMIC STRUCTURES OF WILD-TYPE AND THERMOSTABLE MUTANT RECOMBINANT HUMAN CU, ZN SUPEROXIDE DISMUTASE
分子名称: COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE, ...
著者Parge, H.E, Hallewell, R.A, Tainer, J.A.
登録日1992-02-11
公開日1993-04-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Atomic structures of wild-type and thermostable mutant recombinant human Cu,Zn superoxide dismutase.
Proc.Natl.Acad.Sci.USA, 89, 1992
1CKS
DownloadVisualize
BU of 1cks by Molmil
HUMAN CKSHS2 ATOMIC STRUCTURE: A ROLE FOR ITS HEXAMERIC ASSEMBLY IN CELL CYCLE CONTROL
分子名称: CYCLIN-DEPENDENT KINASE SUBUNIT, TYPE 2, SULFATE ION
著者Parge, H.E, Arvai, A.S, Tainer, J.A.
登録日1993-09-16
公開日1995-02-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human CksHs2 atomic structure: a role for its hexameric assembly in cell cycle control.
Science, 262, 1993
3FRZ
DownloadVisualize
BU of 3frz by Molmil
Crystal Structure of HCV NS5B RNA polymerase in complex with PF868554
分子名称: (6R)-6-cyclopentyl-6-[2-(2,6-diethylpyridin-4-yl)ethyl]-3-[(5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl]-4-hydroxy-5,6-dihydro-2H-pyran-2-one, BETA-MERCAPTOETHANOL, N-[(benzyloxy)carbonyl]-L-alpha-glutamyl-N-[(1S)-4-oxo-4-phenyl-1-propylbut-2-en-1-yl]-L-phenylalaninamide, ...
著者Parge, H.E.
登録日2009-01-08
公開日2009-03-10
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Discovery of (R)-6-cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3-((5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methyl)-4-hydroxy-5,6-dihydropyran-2-one (PF-00868554) as a potent and orally available hepatitis C virus polymerase inhibitor.
J.Med.Chem., 52, 2009
1SPD
DownloadVisualize
BU of 1spd by Molmil
AMYOTROPHIC LATERAL SCLEROSIS AND STRUCTURAL DEFECTS IN CU,ZN SUPEROXIDE DISMUTASE
分子名称: COPPER (II) ION, SUPEROXIDE DISMUTASE, ZINC ION
著者Parge, H.E, Tainer, J.A.
登録日1993-07-21
公開日1994-04-30
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase.
Science, 261, 1993
1YSO
DownloadVisualize
BU of 1yso by Molmil
YEAST CU, ZN SUPEROXIDE DISMUTASE WITH THE REDUCED BRIDGE BROKEN
分子名称: COPPER (I) ION, YEAST CU, ZN SUPEROXIDE DISMUTASE, ...
著者Parge, H.E, Crane, B.R, Tsang, J, Tainer, J.A.
登録日1995-12-21
公開日1996-06-10
最終更新日2018-03-21
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Unusual trigonal-planar copper configuration revealed in the atomic structure of yeast copper-zinc superoxide dismutase.
Biochemistry, 35, 1996
1JCV
DownloadVisualize
BU of 1jcv by Molmil
REDUCED BRIDGE-BROKEN YEAST CU/ZN SUPEROXIDE DISMUTASE LOW TEMPERATURE (-180C) STRUCTURE
分子名称: COPPER (II) ION, CU/ZN SUPEROXIDE DISMUTASE, ZINC ION
著者Ogihara, N.L, Parge, H.E, Hart, P.J, Weiss, M.S, Valentine, J.S, Eisenberg, D.S, Tainer, J.A.
登録日1995-12-07
公開日1996-03-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Unusual trigonal-planar copper configuration revealed in the atomic structure of yeast copper-zinc superoxide dismutase.
Biochemistry, 35, 1996
1AY2
DownloadVisualize
BU of 1ay2 by Molmil
STRUCTURE OF THE FIBER-FORMING PROTEIN PILIN AT 2.6 ANGSTROMS RESOLUTION
分子名称: HEPTANE-1,2,3-TRIOL, PLATINUM (II) ION, TYPE 4 PILIN, ...
著者Forest, K.T, Parge, H.E, Tainer, J.A.
登録日1997-11-13
公開日1998-04-29
最終更新日2023-02-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the fibre-forming protein pilin at 2.6 A resolution.
Nature, 378, 1995
1OS5
DownloadVisualize
BU of 1os5 by Molmil
Crystal structure of HCV NS5B RNA polymerase complexed with a novel non-competitive inhibitor.
分子名称: 3-(4-AMINO-2-TERT-BUTYL-5-METHYL-PHENYLSULFANYL)-6-CYCLOPENTYL-4-HYDROXY-6-[2-(4-HYDROXY-PHENYL)-ETHYL]-5,6-DIHYDRO-PYRAN-2-ONE, Hepatitis C virus NS5B RNA polymerase
著者Love, R.A, Parge, H.E, Yu, X, Hickey, M.J, Diehl, W, Gao, J, Wriggers, H, Ekker, A, Wang, L, Thomson, J.A, Dragovich, P.S, Fuhrman, S.A.
登録日2003-03-18
公開日2004-03-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystallographic identification of a noncompetitive inhibitor binding site on the hepatitis C virus NS5B RNA polymerase enzyme.
J.Virol., 77, 2003
1VAR
DownloadVisualize
BU of 1var by Molmil
MITOCHONDRIAL MANGANESE SUPEROXIDE DISMUTASE VARIANT WITH ILE 58 REPLACED BY THR
分子名称: MANGANESE (III) ION, MANGANESE SUPEROXIDE DISMUTASE
著者Borgstahl, G.E.O, Parge, H.E, Tainer, J.A.
登録日1996-01-04
公開日1996-06-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Human mitochondrial manganese superoxide dismutase polymorphic variant Ile58Thr reduces activity by destabilizing the tetrameric interface.
Biochemistry, 35, 1996
1A1Q
DownloadVisualize
BU of 1a1q by Molmil
HEPATITIS C VIRUS NS3 PROTEINASE
分子名称: NS3 PROTEINASE, ZINC ION
著者Love, R.A, Parge, H.E, Wickersham, J.A, Hostomsky, Z, Habuka, N, Moomaw, E.W, Adachi, T, Hostomska, Z.
登録日1997-12-12
公開日1998-03-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site.
Cell(Cambridge,Mass.), 87, 1996
1AUI
DownloadVisualize
BU of 1aui by Molmil
HUMAN CALCINEURIN HETERODIMER
分子名称: CALCIUM ION, FE (III) ION, SERINE/THREONINE PHOSPHATASE 2B, ...
著者Kissinger, C.R, Parge, H.E, Knighton, D.R, Pelletier, L.A, Lewis, C.T, Tempczyk, A, Villafranca, J.E.
登録日1997-08-27
公開日1997-12-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex.
Nature, 378, 1995
1N0N
DownloadVisualize
BU of 1n0n by Molmil
Catalytic and Structural Effects of Amino-Acid Substitution at His30 in Human Manganese Superoxide Dismutase
分子名称: MANGANESE (II) ION, SULFATE ION, Superoxide dismutase [Mn]
著者Borgstahl, G.E.O, Parge, H.E, Hickey, M.J, Beyer Jr, W.F, Hallewell, R.A, Tainer, J.A.
登録日2002-10-14
公開日2002-11-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Catalytic and Structural Effects of Amino-Acid Substitution at His30 in Human Manganese Superoxide Dismutase
to be published
1N0J
DownloadVisualize
BU of 1n0j by Molmil
The Structure of Human Mitochondrial MN3+ Superoxide Dismutase Reveals a Novel Tetrameric Interface of Two 4-Helix Bundles
分子名称: MANGANESE (II) ION, Superoxide dismutase [Mn]
著者Borgstahl, G.E.O, Parge, H.E, Tainer, J.A.
登録日2002-10-14
公開日2002-11-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Structure of Human Mitochondrial Mn3+ Superoxide Dismutase Reveals a Novel Tetrameric Interface of Two 4-Helix Bundles
Cell(Cambridge,Mass.), 71, 1992
1XR6
DownloadVisualize
BU of 1xr6 by Molmil
Crystal Structure of RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 1B
分子名称: Genome polyprotein, POTASSIUM ION
著者Love, R.A, Maegley, K.A, Yu, X, Ferre, R.A, Lingardo, L.K, Diehl, W, Parge, H.E, Dragovich, P.S, Fuhrman, S.A.
登録日2004-10-13
公開日2004-10-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy
Structure, 12, 2004
1XR7
DownloadVisualize
BU of 1xr7 by Molmil
Crystal structure of RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 16
分子名称: Genome polyprotein
著者Love, R.A, Maegley, K.A, Yu, X, Ferre, R.A, Lingardo, L.K, Diehl, W, Parge, H.E, Dragovich, P.S, Fuhrman, S.A.
登録日2004-10-13
公開日2004-10-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy
Structure, 12, 2004
1XR5
DownloadVisualize
BU of 1xr5 by Molmil
Crystal Structure of the RNA-dependent RNA Polymerase 3D from human rhinovirus serotype 14
分子名称: Genome polyprotein, SAMARIUM (III) ION
著者Love, R.A, Maegley, K.A, Yu, X, Ferre, R.A, Lingardo, L.K, Diehl, W, Parge, H.E, Dragovich, P.S, Fuhrman, S.A.
登録日2004-10-13
公開日2004-10-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Crystal Structure of the RNA-Dependent RNA Polymerase from Human Rhinovirus: A Dual-Function Target for Common Cold Antiviral Therapy
Structure, 12, 2004

219869

件を2024-05-15に公開中

PDB statisticsPDBj update infoContact PDBjnumon