1NO6
| Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Compound 5 Using a Linked-Fragment Strategy | 分子名称: | 2-[(CARBOXYCARBONYL)(1-NAPHTHYL)AMINO]BENZOIC ACID, Protein-tyrosine phosphatase, non-receptor type 1 | 著者 | Szczepankiewicz, B.G, Liu, G, Hajduk, P.J, Abad-Zapatero, C, Pei, Z, Xin, Z, Lubben, T, Trevillyan, J.M, Stashko, M.A, Ballaron, S.J, Liang, H, Huang, F, Hutchins, C.W, Fesik, S.W, Jirousek, M.R. | 登録日 | 2003-01-15 | 公開日 | 2003-04-08 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery of a Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor
Using a Linked-Fragment Strategy J.Am.Chem.Soc., 125, 2003
|
|
1NNY
| Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Compound 23 Using a Linked-Fragment Strategy | 分子名称: | 3-({5-[(N-ACETYL-3-{4-[(CARBOXYCARBONYL)(2-CARBOXYPHENYL)AMINO]-1-NAPHTHYL}-L-ALANYL)AMINO]PENTYL}OXY)-2-NAPHTHOIC ACID, Protein-tyrosine phosphatase, non-receptor type 1 | 著者 | Szczepankiewicz, B.G, Liu, G, Hajduk, P.J, Abad-Zapatero, C, Pei, Z, Xin, Z, Lubben, T, Trevillyan, J.M, Stashko, M.A, Ballaron, S.J, Liang, H, Huang, F, Hutchins, C.W, Fesik, S.W, Jirousek, M.R. | 登録日 | 2003-01-14 | 公開日 | 2003-04-08 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery of a Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor
Using a Linked-Fragment Strategy J.Am.Chem.Soc., 125, 2003
|
|
1NL9
| Potent, Selective Protein Tyrosine Phosphatase 1B Inhibitor Compound 12 Using a Linked-Fragment Strategy | 分子名称: | 2-{[4-(2-ACETYLAMINO-2-PENTYLCARBAMOYL-ETHYL)-NAPHTHALEN-1-YL]-OXALYL-AMINO}-BENZOIC ACID, Protein-tyrosine phosphatase, non-receptor type 1 | 著者 | Szczepankiewicz, B.G, Liu, G, Hajduk, P.J, Abad-Zapatero, C, Pei, Z, Xin, Z, Lubben, T, Trevillyan, J.M, Stashko, M.A, Ballaron, S.J, Liang, H, Huang, F, Hutchins, C.W, Fesik, S.W, Jirousek, M.R. | 登録日 | 2003-01-06 | 公開日 | 2003-04-08 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery of a Potent, Selective Protein Tyrosine
Phosphatase 1B Inhibitor Using a
Linked-Fragment Strategy J.Am.Chem.Soc., 125, 2003
|
|
8GCI
| |
1PYN
| DUAL-SITE POTENT, SELECTIVE PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR USING A LINKED FRAGMENT STRATEGY AND A MALONATE HEAD ON THE FIRST SITE | 分子名称: | 2-(4-{2-TERT-BUTOXYCARBONYLAMINO-2-[4-(3-HYDROXY-2-METHOXYCARBONYL-PHENOXY)-BUTYLCARBAMOYL]-ETHYL}-PHENOXY)-MALONIC ACID, Protein-tyrosine phosphatase, non-receptor type 1 | 著者 | Szczepankiewicz, B.G, Liu, G, Hajduk, P.J, Abad-Zapatero, C, Zhonghua, P, Lubben, T, Trevillyan, J.M, Stashko, M, Ballaron, S.J, Liang, H. | 登録日 | 2003-07-09 | 公開日 | 2003-09-16 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors. Bioorg.Med.Chem.Lett., 13, 2003
|
|
6J1U
| influenza virus nucleoprotein with a specific inhibitor | 分子名称: | Nucleoprotein, ~{N}-[4-[(4-~{tert}-butylphenyl)carbonylamino]phenyl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide | 著者 | Pang, B, Zhang, W.Z, Zhang, H.M, Hao, Q. | 登録日 | 2018-12-29 | 公開日 | 2020-01-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Discovery of a Novel Specific Inhibitor Targeting Influenza A Virus Nucleoprotein with Pleiotropic Inhibitory Effects on Various Steps of the Viral Life Cycle. J.Virol., 95, 2021
|
|
1EPO
| ENDOTHIA ASPARTIC PROTEINASE (ENDOTHIAPEPSIN) COMPLEXED WITH CP-81,282 (MOR PHE NLE CHF NME) | 分子名称: | ENDOTHIAPEPSIN, N-(morpholin-4-ylcarbonyl)-L-phenylalanyl-N-[(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-(methylamino)-4-oxobutyl]-L-norleucinamide | 著者 | Veerapandian, B, Cooper, J.B, Blundell, T.L. | 登録日 | 1994-07-27 | 公開日 | 1994-12-20 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Direct observation by X-ray analysis of the tetrahedral intermediate of aspartic proteinases. Protein Sci., 1, 1992
|
|
1UPT
| Structure of a complex of the golgin-245 GRIP domain with Arl1 | 分子名称: | ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 1, GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A MEMBER 4, ... | 著者 | Panic, B, Perisic, O, Veprintsev, D.B, Williams, R.L, Munro, S. | 登録日 | 2003-10-12 | 公開日 | 2003-10-30 | 最終更新日 | 2019-10-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Basis for Arl1-Dependent Targeting of Homodimeric Grip Domains to the Golgi Apparatus Mol.Cell, 12, 2003
|
|
2ER7
| X-RAY ANALYSES OF ASPARTIC PROTEINASES.III. THREE-DIMENSIONAL STRUCTURE OF ENDOTHIAPEPSIN COMPLEXED WITH A TRANSITION-STATE ISOSTERE INHIBITOR OF RENIN AT 1.6 ANGSTROMS RESOLUTION | 分子名称: | ENDOTHIAPEPSIN, SULFATE ION, TRANSITION-STATE ISOSTERE INHIBITOR OF RENIN | 著者 | Veerapandian, B, Cooper, J.B, Szelke, M, Blundell, T.L. | 登録日 | 1990-11-12 | 公開日 | 1991-01-15 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | X-ray analyses of aspartic proteinases. III Three-dimensional structure of endothiapepsin complexed with a transition-state isostere inhibitor of renin at 1.6 A resolution. J.Mol.Biol., 216, 1990
|
|
2KJX
| Solution structure of the extracellular domain of JTB | 分子名称: | Jumping translocation breakpoint protein | 著者 | Rousseau, F, Lingel, A, Pan, B, Fairbrother, W.J, Bazan, F. | 登録日 | 2009-06-10 | 公開日 | 2010-08-11 | 最終更新日 | 2012-04-18 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure of the extracellular domain of the jumping translocation breakpoint protein reveals a variation of the midkine fold. J.Mol.Biol., 415, 2012
|
|
2JOA
| HtrA1 bound to an optimized peptide: NMR assignment of PDZ domain and ligand resonances | 分子名称: | Peptide H1-C1, Serine protease HTRA1 | 著者 | Runyon, S.T, Zhang, Y, Appleton, B.A, Sazinksy, S.L, Wu, P, Pan, B, Wiesmann, C, Skelton, N.J, Sidhu, S.S. | 登録日 | 2007-03-01 | 公開日 | 2007-11-20 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and functional analysis of the PDZ domains of human HtrA1 and HtrA3 Protein Sci., 16, 2007
|
|
2HDE
| |
1EV0
| |
1JAJ
| |
2G91
| |
1OSX
| Solution Structure of the Extracellular Domain of BLyS Receptor 3 (BR3) | 分子名称: | Tumor necrosis factor receptor superfamily member 13C | 著者 | Gordon, N.C, Pan, B, Hymowitz, S.G, Yin, J.P, Kelley, R.F, Cochran, A.G, Yan, M, Dixit, V.M, Fairbrother, W.J, Starovasnik, M.A. | 登録日 | 2003-03-20 | 公開日 | 2003-05-27 | 最終更新日 | 2024-10-16 | 実験手法 | SOLUTION NMR | 主引用文献 | BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site Biochemistry, 42, 2003
|
|
1XUT
| Solution structure of TACI-CRD2 | 分子名称: | Tumor necrosis factor receptor superfamily member 13B | 著者 | Hymowitz, S.G, Patel, D.R, Wallweber, H.J, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A. | 登録日 | 2004-10-26 | 公開日 | 2004-11-09 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding. J.Biol.Chem., 280, 2005
|
|
1JUX
| |
1R3Z
| Crystal structures of d(Gm5CGm5CGCGC) and d(GCGCGm5CGm5C): Effects of methylation on alternating DNA octamers | 分子名称: | 5'-D(*GP*(5CM)P*GP*(5CM)P*GP*CP*GP*C)-3' | 著者 | Shi, K, Pan, B, Tippin, D, Sundaralingam, M. | 登録日 | 2003-10-03 | 公開日 | 2003-12-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structures of d(Gm5)CGm5CGCGC) and d(GCGCGm5CGm5C): effects of methylation on alternating DNA octamers. Acta Crystallogr.,Sect.D, 60, 2004
|
|
1R41
| Crystal structures of d(Gm5CGm5CGCGC) and d(GCGCGm5CGm5C): Effects of methylation on alternating DNA octamers | 分子名称: | 5'-D(*GP*CP*GP*CP*GP*(5CM)P*GP*(5CM))-3' | 著者 | Shi, K, Pan, B, Tippin, D, Sundaralingam, M. | 登録日 | 2003-10-03 | 公開日 | 2003-12-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of d(Gm5)CGm5CGCGC) and d(GCGCGm5CGm5C): effects of methylation on alternating DNA octamers. Acta Crystallogr.,Sect.D, 60, 2004
|
|
1OSG
| Complex between BAFF and a BR3 derived peptide presented in a beta-hairpin scaffold | 分子名称: | BR3 derived PEPTIDE, MAGNESIUM ION, Tumor necrosis factor ligand superfamily member 13B | 著者 | Gordon, N.C, Pan, B, Hymowitz, S.G, Yin, J.P, Kelley, R.F, Cochran, A.G, Yan, M, Dixit, V.M, Fairbrother, W.J, Starovasnik, M.A. | 登録日 | 2003-03-19 | 公開日 | 2003-05-27 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site Biochemistry, 42, 2003
|
|
1JZV
| Crystal structure of a bulged RNA from the SL2 stem-loop of the HIV-1 psi-RNA | 分子名称: | 5'-R(*CP*AP*GP*UP*AP*CP*GP*(5IC)P*C)-3', 5'-R(*GP*GP*CP*GP*AP*CP*(5BU)P*G)-3', MAGNESIUM ION | 著者 | Xiong, Y, Sudarsanakumar, C, Deng, J, Pan, B, Sundaralingam, M. | 登録日 | 2001-09-17 | 公開日 | 2003-11-11 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structure of a Bulged RNA from the SL2 Stem-loop of the HIV-1 psi-RNA To be Published
|
|
1M77
| Near Atomic Resolution Crystal Structure of an A-DNA Decamer d(CCCGATCGGG): Cobalt Hexammine Interactions with A-DNA | 分子名称: | 5'-D(*CP*CP*CP*GP*AP*TP*CP*GP*GP*G)-3', COBALT HEXAMMINE(III) | 著者 | Ramakrishnan, B, Sekharudu, C, Pan, B.C, Sundaralingam, M. | 登録日 | 2002-07-18 | 公開日 | 2003-01-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Near-atomic resolution crystal structure of an A-DNA decamer d(CCCGATCGGG): cobalt hexammine interaction with A-DNA. Acta Crystallogr.,Sect.D, 59, 2003
|
|
1XU1
| The crystal structure of APRIL bound to TACI | 分子名称: | NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13, Tumor necrosis factor receptor superfamily member 13B | 著者 | Hymowitz, S.G, Patel, D.R, Wallweber, H.J.A, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A. | 登録日 | 2004-10-25 | 公開日 | 2004-11-09 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding J.Biol.Chem., 280, 2005
|
|
1XU2
| The crystal structure of APRIL bound to BCMA | 分子名称: | NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13, Tumor necrosis factor receptor superfamily member 17 | 著者 | Hymowitz, S.G, Patel, D.R, Wallweber, H.J.A, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A. | 登録日 | 2004-10-25 | 公開日 | 2004-11-09 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding J.Biol.Chem., 280, 2005
|
|