1MSJ
 
 | | TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 T15V | | 分子名称: | PROTEIN (ANTIFREEZE PROTEIN TYPE III) | | 著者 | Graether, S.P, Deluca, C.I, Baardsnes, J, Hill, G.A, Davies, P.L, Jia, Z. | | 登録日 | 1999-01-24 | | 公開日 | 1999-04-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Quantitative and qualitative analysis of type III antifreeze protein structure and function.
J.Biol.Chem., 274, 1999
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1N4I
 | | Solution structure of spruce budworm antifreeze protein at 5 degrees celsius | | 分子名称: | thermal hysteresis protein | | 著者 | Graether, S.P, Gagne, S.M, Spyracopoulos, L, Jia, Z, Davies, P.L, Sykes, B.D. | | 登録日 | 2002-10-31 | | 公開日 | 2003-04-08 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Spruce Budworm Antifreeze Protein: Changes in Structure and Dynamics at Low Temperature
J.Mol.Biol., 327, 2003
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2W7X
 | | Cellular inhibition of checkpoint kinase 2 and potentiation of cytotoxic drugs by novel Chk2 inhibitor PV1019 | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, N-[4-[(E)-N-carbamimidamido-C-methyl-carbonimidoyl]phenyl]-7-nitro-1H-indole-2-carboxamide, ... | | 著者 | Jobson, A.G, Lountos, G.T, Lorenzi, P.L, Llamas, J, Connelly, J, Tropea, J.E, Onda, A, Kondapaka, S, Zhang, G, Caplen, N.J, Caredellina, J.H, Monks, A, Self, C, Waugh, D.S, Shoemaker, R.H, Pommier, Y. | | 登録日 | 2009-01-06 | | 公開日 | 2009-09-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Cellular Inhibition of Chk2 Kinase and Potentiation of Camptothecins and Radiation by the Novel Chk2 Inhibitor Pv1019.
J.Pharmacol.Exp.Ther., 331, 2009
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3P4G
 | | X-ray crystal structure of a hyperactive, Ca2+-dependent, beta-helical antifreeze protein from an Antarctic bacterium | | 分子名称: | ACETATE ION, Antifreeze protein, CALCIUM ION, ... | | 著者 | Garnham, C.P, Campbell, R.L, Davies, P.L. | | 登録日 | 2010-10-06 | | 公開日 | 2011-04-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Anchored clathrate waters bind antifreeze proteins to ice.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3MMS
 | | Crystal structure of Streptococcus pneumoniae MTA/SAH nucleosidase in complex with 8-aminoadenine | | 分子名称: | 5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase, 9H-purine-6,8-diamine, GLYCEROL | | 著者 | Siu, K.K.W, Lee, J.E, Horvatin-Mrakovcic, C, Howell, P.L. | | 登録日 | 2010-04-20 | | 公開日 | 2010-05-12 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of Streptococcus pneumoniae MTA/SAH nucleosidase in complex with 8-aminoadenine
TO BE PUBLISHED
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3MSI
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2VXH
 | | The crystal structure of chlorite dismutase: a detox enzyme producing molecular oxygen | | 分子名称: | CARBONATE ION, CHLORITE DISMUTASE, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | De Geus, D.C, Thomassen, E.A.J, Hagedoorn, P.L, Pannu, N.S, Abrahams, J.P. | | 登録日 | 2008-07-04 | | 公開日 | 2009-03-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of Chlorite Dismutase, a Detoxifying Enzyme Producing Molecular Oxygen
J.Mol.Biol., 387, 2009
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2XVC
 | | Molecular and structural basis of ESCRT-III recruitment to membranes during archaeal cell division | | 分子名称: | CADMIUM ION, CDVA, SSO0911, ... | | 著者 | Samson, R.Y, Obita, T, Hodgson, B, Shaw, M.K, Chong, P.L, Williams, R.L, Bell, S.D. | | 登録日 | 2010-10-25 | | 公開日 | 2011-02-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Molecular and Structural Basis of Escrt-III Recruitment to Membranes During Archaeal Cell Division.
Mol.Cell, 41, 2011
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3O4V
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2W2D
 | | Crystal Structure of a Catalytically Active, Non-toxic Endopeptidase Derivative of Clostridium botulinum Toxin A | | 分子名称: | ACETATE ION, BOTULINUM NEUROTOXIN A HEAVY CHAIN, BOTULINUM NEUROTOXIN A LIGHT CHAIN, ... | | 著者 | Masuyer, G, Thiyagarajan, N, James, P.L, Marks, P.M.H, Chaddock, J.A, Acharya, K.R. | | 登録日 | 2008-10-29 | | 公開日 | 2009-03-24 | | 最終更新日 | 2022-05-04 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Crystal Structure of a Catalytically Active, Non-Toxic Endopeptidase Derivative of Clostridium Botulinum Toxin A.
Biochem.Biophys.Res.Commun., 381, 2009
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3PG0
 | | Crystal structure of designed 3-fold symmetric protein, ThreeFoil | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, SODIUM ION, ... | | 著者 | Lobsanov, Y.D, Broom, A, Howell, P.L, Rose, D.R, Meiering, E.M. | | 登録日 | 2010-10-29 | | 公開日 | 2011-12-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Modular evolution and the origins of symmetry: reconstruction of a three-fold symmetric globular protein.
Structure, 20, 2012
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6OJZ
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2R9C
 | | Calpain 1 proteolytic core inactivated by ZLAK-3001, an alpha-ketoamide | | 分子名称: | CALCIUM ION, CHLORIDE ION, Calpain-1 catalytic subunit, ... | | 著者 | Qian, J, Campbell, R.L, Davies, P.L. | | 登録日 | 2007-09-12 | | 公開日 | 2008-08-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Cocrystal structures of primed side-extending alpha-ketoamide inhibitors reveal novel calpain-inhibitor aromatic interactions.
J.Med.Chem., 51, 2008
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2RIV
 | | Crystal structure of the reactive loop cleaved human Thyroxine Binding Globulin | | 分子名称: | GLYCEROL, SULFATE ION, Thyroxine-binding globulin | | 著者 | Zhou, A, Wei, Z, Stanley, P.L.D, Read, R.J, Stein, P.E, Carrell, R.W. | | 登録日 | 2007-10-12 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins
J.Biol.Chem., 286, 2011
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6OLL
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2R9F
 | | Calpain 1 proteolytic core inactivated by ZLAK-3002, an alpha-ketoamide | | 分子名称: | CALCIUM ION, CHLORIDE ION, Calpain-1 catalytic subunit, ... | | 著者 | Qian, J, Campbell, R.L, Davies, P.L. | | 登録日 | 2007-09-12 | | 公開日 | 2008-08-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Cocrystal structures of primed side-extending alpha-ketoamide inhibitors reveal novel calpain-inhibitor aromatic interactions.
J.Med.Chem., 51, 2008
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6OK2
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2RI9
 | | Penicillium citrinum alpha-1,2-mannosidase in complex with a substrate analog | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Lobsanov, Y.D, Yoshida, T, Desmet, T, Nerinckx, W, Yip, P, Claeyssens, M, Herscovics, A, Howell, P.L. | | 登録日 | 2007-10-10 | | 公開日 | 2008-03-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Modulation of activity by Arg407: structure of a fungal alpha-1,2-mannosidase in complex with a substrate analogue.
Acta Crystallogr.,Sect.D, 64, 2008
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6OD6
 | | Structure of BACE-1 in complex with Ligand 13 | | 分子名称: | Beta-secretase 1, GLYCEROL, N-{3-[(3R)-1-amino-3-methyl-3,4-dihydropyrrolo[1,2-a]pyrazin-3-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide | | 著者 | Shaffer, P.L. | | 登録日 | 2019-03-26 | | 公開日 | 2019-09-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Evaluation of a Series of beta-Secretase 1 Inhibitors Containing Novel Heteroaryl-Fused-Piperazine Amidine Warheads.
Acs Med.Chem.Lett., 10, 2019
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6OLJ
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2RIW
 | | The Reactive loop cleaved human Thyroxine Binding Globulin complexed with thyroxine | | 分子名称: | 3,5,3',5'-TETRAIODO-L-THYRONINE, Thyroxine-binding globulin | | 著者 | Zhou, A, Wei, Z, Stanley, P.L.D, Read, R.J, Stein, P.E, Carrell, R.W. | | 登録日 | 2007-10-12 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins
J.Biol.Chem., 286, 2011
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2SPG
 | | TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 T15S | | 分子名称: | PROTEIN (ANTIFREEZE PROTEIN TYPE III) | | 著者 | Graether, S.P, Deluca, C.I, Baardsnes, J, Hill, G.A, Davies, P.L, Jia, Z. | | 登録日 | 1999-01-21 | | 公開日 | 1999-04-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Quantitative and qualitative analysis of type III antifreeze protein structure and function.
J.Biol.Chem., 274, 1999
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7WRO
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6P9E
 | | Crystal structure of IL-36gamma complexed to A-552 | | 分子名称: | (2S)-2-{[4-(3-amino-4-methylphenyl)-6-methylpyrimidin-2-yl]oxy}-3-methoxy-3,3-diphenylpropanoic acid, Interleukin-36 gamma | | 著者 | Argiriadi, M.A, Todorovic, T, Su, Z, Putman, B, Kakavas, S.J, Salte, K.M, McDonald, H.A, Wetter, J.B, Paulsboe, S.E, Sun, Q, Gerstein, C.E, Medina, L, Sielaff, B, Sadhukhan, R, Stockmann, H, Richardson, P.L, Qiu, W, Henry, R.F, Herold, J.M, Shotwell, J.B, McGaraughty, S.P, Honore, P, Gopalakrishnan, S.M, Sun, C.C, Scott, V.E. | | 登録日 | 2019-06-10 | | 公開日 | 2019-06-26 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Small Molecule IL-36 gamma Antagonist as a Novel Therapeutic Approach for Plaque Psoriasis.
Sci Rep, 9, 2019
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7XX6
 | | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment) | | 分子名称: | CALCIUM ION, DNA (169-MER), Histone H1.0, ... | | 著者 | Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A. | | 登録日 | 2022-05-28 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.39 Å) | | 主引用文献 | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment)
To Be Published
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