4F9V
 
 | | Structure of C113A/C136A mutant variant of glycosylated glutaminyl cyclase from Drosophila melanogaster | | Descriptor: | 1-(3,4-dimethoxyphenyl)-3-[3-(1H-imidazol-1-yl)propyl]thiourea, CG32412, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Kolenko, P, Koch, B, Ruiz-Carilo, D, Stubbs, M.T. | | Deposit date: | 2012-05-21 | | Release date: | 2012-08-29 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structures of Glutaminyl Cyclases (QCs) from Drosophila melanogaster Reveal Active Site Conservation between Insect and Mammalian QCs.
Biochemistry, 51, 2012
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6KNP
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1MXO
 | | AmpC beta-lactamase in complex with an m.carboxyphenylglycylboronic acid bearing the cephalothin R1 side chain | | Descriptor: | (1R)-1-(2-THIENYLACETYLAMINO)-1-(3-CARBOXYPHENYL)METHYLBORONIC ACID, Beta-lactamase, PHOSPHATE ION | | Authors: | Morandi, F, Caselli, E, Morandi, S, Focia, P.J, Blazquez, J, Shoichet, B.K, Prati, F. | | Deposit date: | 2002-10-02 | | Release date: | 2003-03-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.83 Å) | | Cite: | Nanomolar inhibitors of AmpC beta-lactamase.
J.Am.Chem.Soc., 125, 2003
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4FDX
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1MY8
 | | AmpC beta-lactamase in complex with an M.carboxyphenylglycylboronic acid bearing the cephalothin R1 side chain | | Descriptor: | (1R)-1-(2-THIENYLACETYLAMINO)-1-PHENYLMETHYLBORONIC ACID, PHOSPHATE ION, beta-lactamase | | Authors: | Morandi, F, Caselli, E, Morandi, S, Focia, P.J, Blazquez, J, Shoichet, B.K, Prati, F. | | Deposit date: | 2002-10-03 | | Release date: | 2003-03-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Nanomolar inhibitors of AmpC beta-lactamase.
J.Am.Chem.Soc., 125, 2003
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3HF1
 | | Crystal structure of human p53R2 | | Descriptor: | FE (III) ION, Ribonucleoside-diphosphate reductase subunit M2 B, SULFATE ION | | Authors: | Smith, P, Zhou, B, Yuan, Y.-C, Su, L, Tsai, S.-C, Yen, Y. | | Deposit date: | 2009-05-10 | | Release date: | 2009-10-13 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | 2.6 A X-ray crystal structure of human p53R2, a p53-inducible ribonucleotide reductase .
Biochemistry, 48, 2009
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4FD9
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1MZ5
 | | Trypanosoma rangeli sialidase | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, sialidase | | Authors: | Buschiazzo, A, Tavares, G.A, Campetella, O, Spinelli, S, Cremona, M.L, Paris, G, Amaya, M.F, Frasch, A.C.C, Alzari, P.M. | | Deposit date: | 2002-10-05 | | Release date: | 2002-10-16 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis of sialyltransferase activity in trypanosomal sialidases
Embo J., 19, 2000
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4FFN
 | | PylC in complex with D-ornithine and AMPPNP | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, D-ORNITHINE, MAGNESIUM ION, ... | | Authors: | Quitterer, F, List, A, Beck, P, Bacher, A, Groll, M. | | Deposit date: | 2012-06-01 | | Release date: | 2012-09-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Biosynthesis of the 22nd genetically encoded amino acid pyrrolysine: structure and reaction mechanism of PylC at 1.5A resolution.
J.Mol.Biol., 424, 2012
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1N2L
 | | Crystal structure of a covalent intermediate of endogenous human arylsulfatase A | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ARYLSULFATASE A, ... | | Authors: | Chruszcz, M, Laidler, P, Monkiewicz, M, Ortlund, E, Lebioda, L, Lewinski, K. | | Deposit date: | 2002-10-23 | | Release date: | 2003-12-23 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structure of a covalent intermediate of endogenous human arylsulfatase A.
J.Inorg.Biochem., 96, 2003
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5KP8
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1MR5
 | | Orthorhombic form of Trypanosoma cruzi trans-sialidase | | Descriptor: | trans-sialidase | | Authors: | Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M. | | Deposit date: | 2002-09-18 | | Release date: | 2003-03-18 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
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1MS8
 | | Triclinic form of Trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-N-acetylneuraminic acid (DANA) | | Descriptor: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, trans-sialidase | | Authors: | Buschiazzo, A, Amaya, M.F, Cremona, M.L, Frasch, A.C, Alzari, P.M. | | Deposit date: | 2002-09-19 | | Release date: | 2003-03-25 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The crystal structure and mode of action of trans-sialidase, a key enzyme in Trypanosoma cruzi pathogenesis
Mol.Cell, 10, 2002
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3HJT
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1MVQ
 | | Cratylia mollis lectin (isoform 1) in complex with methyl-alpha-D-mannose | | Descriptor: | CALCIUM ION, MANGANESE (II) ION, lectin, ... | | Authors: | de Souza, G.A, Oliveira, P.S, Trapani, S, Correia, M.T, Oliva, G, Coelho, L.C, Greene, L.J. | | Deposit date: | 2002-09-26 | | Release date: | 2003-10-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Amino acid sequence and tertiary structure of Cratylia mollis seed lectin
Glycobiology, 13, 2003
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7RCO
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3UP2
 | | Aurora A in complex with RPM1686 | | Descriptor: | 1,2-ETHANEDIOL, 4-[(4-{[2-(trifluoromethoxy)phenyl]amino}pyrimidin-2-yl)amino]benzoic acid, Aurora kinase A | | Authors: | Martin, M.P, Zhu, J.-Y, Schonbrunn, E. | | Deposit date: | 2011-11-17 | | Release date: | 2012-01-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.3001 Å) | | Cite: | A Novel Mechanism by Which Small Molecule Inhibitors Induce the DFG Flip in Aurora A.
Acs Chem.Biol., 7, 2012
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1MZH
 | | QR15, an Aldolase | | Descriptor: | Deoxyribose-phosphate aldolase, PHOSPHATE ION | | Authors: | Tan, A.Y, Smith, P.C, Shen, J, Xiao, R, Acton, T, Rost, B, Montelione, G, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2002-10-07 | | Release date: | 2003-02-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of Aquifex Aeolicus Aldolase,
Northeast Structural Genomics Consortium Target
QR15
To be Published
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5KJV
 | | Crystal structure of Coleus blumei HCT | | Descriptor: | Hydroxycinnamoyl transferase | | Authors: | Levsh, O, Chiang, Y.C, Tung, C.F, Noel, J.P, Wang, Y, Weng, J.K. | | Deposit date: | 2016-06-20 | | Release date: | 2016-11-02 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Dynamic Conformational States Dictate Selectivity toward the Native Substrate in a Substrate-Permissive Acyltransferase.
Biochemistry, 55, 2016
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3UPG
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5KUT
 | | hMiro2 C-terminal GTPase domain, GDP-bound | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Mitochondrial Rho GTPase 2 | | Authors: | Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M. | | Deposit date: | 2016-07-13 | | Release date: | 2016-09-21 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.693 Å) | | Cite: | Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
Sci Rep, 6, 2016
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1N11
 | | D34 REGION OF HUMAN ANKYRIN-R AND LINKER | | Descriptor: | Ankyrin, BROMIDE ION, CHLORIDE ION | | Authors: | Michaely, P, Tomchick, D.R, Machius, M, Anderson, R.G.W. | | Deposit date: | 2002-10-16 | | Release date: | 2002-12-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of a 12 ANK repeat stack from human ankyrinR
Embo J., 21, 2002
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4FNM
 | | The alpha-esterase-7 carboxylesterase, E3, from the blowfly Lucilia cuprina | | Descriptor: | DIETHYL HYDROGEN PHOSPHATE, E3 alpha-esterase-7 carboxylesterase | | Authors: | Jackson, C.J, Liu, J.-W, Carr, P.D, Younis, F, Pandey, G, Coppin, C, Meirelles, T, Ollis, D.L, Tawfik, D.S, Weik, M, Oakeshott, J.G. | | Deposit date: | 2012-06-20 | | Release date: | 2013-12-04 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.804 Å) | | Cite: | Structure and function of an insect alpha-carboxylesterase ( alpha Esterase7) associated with insecticide resistance.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4FNU
 | | Crystal structure of GH36 alpha-galactosidase AgaA A355E D478A from Geobacillus stearothermophilus in complex with stachyose | | Descriptor: | Alpha-galactosidase AgaA, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose-(1-6)-alpha-D-galactopyranose-(1-6)-alpha-D-galactopyranose | | Authors: | Merceron, R, Foucault, M, Haser, R, Mattes, R, Watzlawick, H, Gouet, P. | | Deposit date: | 2012-06-20 | | Release date: | 2012-10-03 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | The molecular mechanism of the thermostable alpha-galactosidases AgaA and AgaB explained by X-ray crystallography and mutational studies
J.Biol.Chem., 287, 2012
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1MYZ
 | | CO COMPLEX OF MYOGLOBIN MB-YQR AT RT SOLVED FROM LAUE DATA. | | Descriptor: | CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Bourgeois, D, Vallone, B, Schotte, F, Arcovito, A, Miele, A.E, Sciara, G, Wulff, M, Anfinrud, P, Brunori, M. | | Deposit date: | 2002-10-04 | | Release date: | 2003-08-19 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Complex landscape of protein
structural dynamics unveiled by
nanosecond Laue crystallography.
Proc.Natl.Acad.Sci.USA, 100, 2003
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