8FNU
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![BU of 8fnu by Molmil](/molmil-images/mine/8fnu) | Structure of RdrA from Streptococcus suis RADAR defense system | Descriptor: | KAP NTPase domain-containing protein | Authors: | Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. | Deposit date: | 2022-12-28 | Release date: | 2023-02-01 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Cryo-EM structure of the RADAR supramolecular anti-phage defense complex. Cell, 186, 2023
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6RLM
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![BU of 6rlm by Molmil](/molmil-images/mine/6rlm) | Crystal structure of AT1412dm Fab fragment | Descriptor: | AT1412dm Fab (Heavy Chain), AT1412dm Fab (Light Chain), CHLORIDE ION | Authors: | Neviani, V, Pearce, N.M, Pos, W, Schotte, R, Spits, H, Gros, P. | Deposit date: | 2019-05-02 | Release date: | 2021-05-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of a homo-dimerization site in tetraspanin CD9 targeted by a melanoma patient-derived antibody To Be Published
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8UHV
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![BU of 8uhv by Molmil](/molmil-images/mine/8uhv) | X-ray crystal structure of Toxoplasma gondii Apo GalNAc-T3 | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Glycosyl transferase | Authors: | Kumar, P, Samara, N.L. | Deposit date: | 2023-10-09 | Release date: | 2024-05-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A Toxoplasma gondii O-glycosyltransferase that modulates bradyzoite cyst wall rigidity is distinct from host homologues. Nat Commun, 15, 2024
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6RLO
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![BU of 6rlo by Molmil](/molmil-images/mine/6rlo) | Crystal structure of AT1412dm Fab fragment in complex with CD9 large extracellular loop | Descriptor: | AT1412dm Fab Fragment (Heavy Chain), AT1412dm Fab Fragment (Light Chain), CD9 antigen, ... | Authors: | Neviani, V, Pearce, N.M, Pos, W, Schotte, R, Spits, H, Gros, P. | Deposit date: | 2019-05-02 | Release date: | 2021-05-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis of a homo-dimerization site in tetraspanin CD9 targeted by a melanoma patient-derived antibody To Be Published
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7KHA
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![BU of 7kha by Molmil](/molmil-images/mine/7kha) | Cryo-EM Structure of the Desulfovibrio vulgaris Type I-C Apo Cascade | Descriptor: | CRISPR-associated protein, CT1133 family, CT1134 family, ... | Authors: | O'Brien, R, Wrapp, D, Bravo, J.P.K, Schwartz, E, Taylor, D. | Deposit date: | 2020-10-20 | Release date: | 2020-11-11 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Structural basis for assembly of non-canonical small subunits into type I-C Cascade. Nat Commun, 11, 2020
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4D7P
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![BU of 4d7p by Molmil](/molmil-images/mine/4d7p) | Superoxide reductase (1Fe-SOR) from Giardia intestinalis | Descriptor: | FE (III) ION, SUPEROXIDE REDUCTASE | Authors: | Sousa, C.M, Carpentier, P, Matias, P.M, Testa, F, Pinho, F.G, Sarti, P, Giuffre, A, Bandeiras, T.M, Romao, C.V. | Deposit date: | 2014-11-26 | Release date: | 2015-10-07 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Superoxide Reductase from Giardia Intestinalis: Structural Characterization of the First Sor from a Eukaryotic Organism Shows an Iron Centre that is Highly Sensitive to Photoreduction. Acta Crystallogr.,Sect.D, 71, 2015
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8UJH
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![BU of 8ujh by Molmil](/molmil-images/mine/8ujh) | X-ray crystal structure of Toxoplasma gondii GalNAc-T3 in complex with UDP-GalNAc, Mn2+, and a CST1 diglycopeptide. | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, GLYCEROL, Glycosyl transferase, ... | Authors: | Kumar, P, Samara, N.L. | Deposit date: | 2023-10-11 | Release date: | 2024-05-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | A Toxoplasma gondii O-glycosyltransferase that modulates bradyzoite cyst wall rigidity is distinct from host homologues. Nat Commun, 15, 2024
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1NFV
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![BU of 1nfv by Molmil](/molmil-images/mine/1nfv) | X-ray structure of Desulfovibrio desulfuricans bacterioferritin: the diiron centre in different catalytic states (as-isolated structure) | Descriptor: | 1,3,5,8-TETRAMETHYL-PORPHINE-2,4,6,7-TETRAPROPIONIC ACID FERROUS COMPLEX, 3-HYDROXYPYRUVIC ACID, FE (III) ION, ... | Authors: | Macedo, S, Romao, C.V, Mitchell, E, Matias, P.M, Liu, M.Y, Xavier, A.V, LeGall, J, Teixeira, M, Lindley, P, Carrondo, M.A. | Deposit date: | 2002-12-16 | Release date: | 2003-04-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The nature of the di-iron site in the bacterioferritin from
Desulfovibrio desulfuricans NAT.STRUCT.BIOL., 10, 2003
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8UI1
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![BU of 8ui1 by Molmil](/molmil-images/mine/8ui1) | |
8UJE
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![BU of 8uje by Molmil](/molmil-images/mine/8uje) | X-ray crystal structure of Toxoplasma gondii GalNAc-T3 in complex with UDP-GalNAc, Mn2+, and Muc5AC-3,13 | Descriptor: | DI(HYDROXYETHYL)ETHER, Glycosyl transferase, MANGANESE (II) ION, ... | Authors: | Kumar, P, Samara, N.L. | Deposit date: | 2023-10-11 | Release date: | 2024-05-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A Toxoplasma gondii O-glycosyltransferase that modulates bradyzoite cyst wall rigidity is distinct from host homologues. Nat Commun, 15, 2024
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2UUN
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![BU of 2uun by Molmil](/molmil-images/mine/2uun) | Crystal structure of C-phycocyanin from Phormidium, Lyngbya spp. (Marine) and Spirulina sp. (Fresh water) shows two different ways of energy transfer between two hexamers. | Descriptor: | BILIVERDINE IX ALPHA, C-PHYCOCYANIN, PHYCOCYANOBILIN | Authors: | Satyanarayana, L, Patel, A, Mishra, S, K Ghosh, P, Suresh, C.G. | Deposit date: | 2007-03-05 | Release date: | 2008-05-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structure of C-Phycocyanin from Phormidium, Lyngbya Spp. (Marine) and Spirulina Sp. (Fresh Water) Shows Two Different Ways of Energy Transfer between Two Hexamers. To be Published
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8FH3
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![BU of 8fh3 by Molmil](/molmil-images/mine/8fh3) | Human IFT-A complex structures provide molecular insights into ciliary transport | Descriptor: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 140 homolog, Tubby-related protein 3, ... | Authors: | Jiang, M, Palicharla, V.R, Miller, D, Hwang, S.H, Zhu, H, Hixson, P, Mukhopadhyay, S, Sun, J. | Deposit date: | 2022-12-13 | Release date: | 2023-02-22 | Last modified: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Human IFT-A complex structures provide molecular insights into ciliary transport. Cell Res., 33, 2023
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6RPV
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![BU of 6rpv by Molmil](/molmil-images/mine/6rpv) | Extremely stable monomeric variant of human cystatin C with single amino acid substitution | Descriptor: | Cystatin-C | Authors: | Zhukov, I, Rodziewicz-Motowidlo, S, Maszota-Zieleniak, M, Jurczak, P, Kozak, M. | Deposit date: | 2019-05-14 | Release date: | 2019-07-31 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR, SOLUTION SCATTERING | Cite: | NMR and crystallographic structural studies of the extremely stable monomeric variant of human cystatin C with single amino acid substitution. Febs J., 287, 2020
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8FGW
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![BU of 8fgw by Molmil](/molmil-images/mine/8fgw) | Human IFT-A complex structures provide molecular insights into ciliary transport | Descriptor: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 140 homolog, Intraflagellar transport protein 43 homolog, ... | Authors: | Jiang, M, Palicharla, V.R, Miller, D, Hwang, S.H, Zhu, H, Hixson, P, Mukhopadhyay, S, Sun, J. | Deposit date: | 2022-12-12 | Release date: | 2023-02-22 | Last modified: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Human IFT-A complex structures provide molecular insights into ciliary transport. Cell Res., 33, 2023
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4MM1
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![BU of 4mm1 by Molmil](/molmil-images/mine/4mm1) | GGGPS from Methanothermobacter thermautotrophicus | Descriptor: | Geranylgeranylglyceryl phosphate synthase, SN-GLYCEROL-1-PHOSPHATE, TRIETHYLENE GLYCOL | Authors: | Rajendran, C, Peterhoff, D, Beer, B, Kumpula, E.P, Kapetaniou, E, Guldan, H, Wierenga, R.K, Sterner, R, Babinger, P. | Deposit date: | 2013-09-07 | Release date: | 2014-06-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8004 Å) | Cite: | A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization. Mol.Microbiol., 92, 2014
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5FEP
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![BU of 5fep by Molmil](/molmil-images/mine/5fep) | HydE from T. maritima in complex with (2R,4R)-MeTDA | Descriptor: | (2R,4R)-2-methyl-1,3-thiazolidine-2,4-dicarboxylic acid, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CHLORIDE ION, ... | Authors: | Rohac, R, Amara, P, Benjdia, A, Martin, L, Ruffie, P, Favier, A, Berteau, O, Mouesca, J.M, Fontecilla-Camps, J.C, Nicolet, Y. | Deposit date: | 2015-12-17 | Release date: | 2016-04-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Carbon-sulfur bond-forming reaction catalysed by the radical SAM enzyme HydE. Nat.Chem., 8, 2016
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8FPT
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![BU of 8fpt by Molmil](/molmil-images/mine/8fpt) | STRUCTURE OF ALPHA-SYNUCLEIN FIBRILS DERIVED FROM HUMAN LEWY BODY DEMENTIA TISSUE | Descriptor: | Alpha-synuclein | Authors: | Barclay, A.M, Dhavale, D.D, Borcik, C.G, Rau, M.J, Basore, K, Milchberg, M.H, Warmuth, O.A, Kotzbauer, P.T, Rienstra, C.M, Schwieters, C.D. | Deposit date: | 2023-01-05 | Release date: | 2023-02-22 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Structure of alpha-synuclein fibrils derived from human Lewy body dementia tissue. Biorxiv, 2023
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6EYK
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![BU of 6eyk by Molmil](/molmil-images/mine/6eyk) | E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic ligand NV355 | Descriptor: | (2~{S})-3-cyclohexyl-2-[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[(1~{R},2~{R},3~{S})-3-methyl-2-[(2~{R},3~{S},4~{R},5~{S},6~{R})-3,4,5-tris(oxidanyl)-6-(trifluoromethyl)oxan-2-yl]oxy-cyclohexyl]oxy-3,5-bis(oxidanyl)oxan-4-yl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Jakob, R.P, Zihlmann, P, Preston, R.C, Varga, N, Ernst, B, Maier, T. | Deposit date: | 2017-11-13 | Release date: | 2018-11-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | E-selectin lectin with different glycomimetic ligands To Be Published
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1K29
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![BU of 1k29 by Molmil](/molmil-images/mine/1k29) | Solution Structure of a DNA Duplex Containing M1G Opposite a 2 Base Pair Deletion | Descriptor: | 5'-D(*AP*TP*CP*GP*CP*(M1G)P*CP*GP*GP*CP*AP*TP*G)-3', 5'-D(*CP*AP*TP*GP*CP*CP*GP*CP*GP*AP*T)-3' | Authors: | Schnetz-Boutaud, N.C, Saleh, S, Marnett, L.J, Stone, M.P. | Deposit date: | 2001-09-26 | Release date: | 2002-01-16 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The exocyclic 1,N2-deoxyguanosine pyrimidopurinone M1G is a chemically stable DNA adduct when placed opposite a two-base deletion in the (CpG)3 frameshift hotspot of the Salmonella typhimurium hisD3052 gene. Biochemistry, 40, 2001
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6JAR
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![BU of 6jar by Molmil](/molmil-images/mine/6jar) | Crystal structure of ABC transporter alpha-glycoside-binding mutant protein R49A in complex with maltose | Descriptor: | 1,2-ETHANEDIOL, ABC transporter, periplasmic substrate-binding protein, ... | Authors: | Kanaujia, S.P, Chandravanshi, M, Gogoi, P. | Deposit date: | 2019-01-24 | Release date: | 2019-10-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Structural and thermodynamic correlation illuminates the selective transport mechanism of disaccharide alpha-glycosides through ABC transporter. Febs J., 287, 2020
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6S9N
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![BU of 6s9n by Molmil](/molmil-images/mine/6s9n) | Designed Armadillo Repeat protein Lock2 fused to target peptide KRKRKAKLSF | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Lock2_KRKRKAKLSF | Authors: | Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A. | Deposit date: | 2019-07-15 | Release date: | 2020-02-19 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-Guided Design of a Peptide Lock for Modular Peptide Binders. Acs Chem.Biol., 15, 2020
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2UZB
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![BU of 2uzb by Molmil](/molmil-images/mine/2uzb) | Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor | Descriptor: | 4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-FURYL}-N-METHYLBENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2, CYCLIN-A2 | Authors: | Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. | Deposit date: | 2007-04-27 | Release date: | 2007-06-26 | Last modified: | 2019-04-03 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Discovery of a Potent Cdk2 Inhibitor with a Novel Binding Mode, Using Virtual Screening and Initial, Structure-Guided Lead Scoping. Bioorg.Med.Chem.Lett., 17, 2007
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8FTU
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![BU of 8ftu by Molmil](/molmil-images/mine/8ftu) | Crystal structure of the SNARE Use1 bound to Dsl1 complex subunits Sec39 and Dsl1, Revised Use1 structure | Descriptor: | Protein transport protein DSL1, Protein transport protein SEC39, Vesicle transport protein USE1 | Authors: | Travis, S.M, Jeffrey, P.D, Hughson, F.M. | Deposit date: | 2023-01-13 | Release date: | 2023-03-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (5.73 Å) | Cite: | Structure of a membrane tethering complex incorporating multiple SNAREs. Nat.Struct.Mol.Biol., 31, 2024
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2UZD
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![BU of 2uzd by Molmil](/molmil-images/mine/2uzd) | Crystal structure of human CDK2 complexed with a thiazolidinone inhibitor | Descriptor: | 4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2 | Authors: | Richardson, C.M, Dokurno, P, Murray, J.B, Surgenor, A.E. | Deposit date: | 2007-04-27 | Release date: | 2007-06-26 | Last modified: | 2019-04-03 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Discovery of a Potent Cdk2 Inhibitor with a Novel Binding Mode, Using Virtual Screening and Initial, Structure-Guided Lead Scoping. Bioorg.Med.Chem.Lett., 17, 2007
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8PWZ
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![BU of 8pwz by Molmil](/molmil-images/mine/8pwz) | Crystal Structure of (3R)-hydroxyacyl-ACP dehydratase HadBD from Mycobacterium tuberculosis | Descriptor: | (3R)-hydroxyacyl-ACP dehydratase subunit HadB, UPF0336 protein Rv0504c | Authors: | Rima, J, Grimoire, Y, Bories, P, Bardou, F, Quemard, A, Bon, C, Mourey, L, Tranier, S. | Deposit date: | 2023-07-22 | Release date: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.00196719 Å) | Cite: | HadBD dehydratase from Mycobacterium tuberculosis fatty acid synthase type II: A singular structure for a unique function. Protein Sci., 33, 2024
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