6ILR
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8HW9
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![BU of 8hw9 by Molmil](/molmil-images/mine/8hw9) | Solution structure of ubiquitin-like domain (UBL) of human ZFAND1 | Descriptor: | AN1-type zinc finger protein 1 | Authors: | Lai, C.H, Ko, K.T, Fan, P.J, Yu, T.A, Chang, C.F, Hsu, S.T.D. | Deposit date: | 2022-12-29 | Release date: | 2024-01-31 | Last modified: | 2024-08-14 | Method: | SOLUTION NMR | Cite: | Structural insight into the ZFAND1-p97 interaction involved in stress granule clearance. J.Biol.Chem., 300, 2024
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8ESS
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![BU of 8ess by Molmil](/molmil-images/mine/8ess) | Myoglobin variant Mb-cIII complex | Descriptor: | Myoglobin, SULFATE ION, [2,18-bis(2-carboxyethyl)-7,12-diethenyl-3,8,13,17-tetramethyl-21-(2-oxo-3-phenylpropyl)porphyrin-21-iumato(2-)-kappa~3~N~22~,N~23~,N~24~]iron(2+) | Authors: | Bacik, J.P, Fasan, R, Ando, N. | Deposit date: | 2022-10-14 | Release date: | 2023-12-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Mechanistic manifold in a hemoprotein-catalyzed cyclopropanation reaction with diazoketone. Nat Commun, 14, 2023
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3J5M
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![BU of 3j5m by Molmil](/molmil-images/mine/3j5m) | Cryo-EM structure of the BG505 SOSIP.664 HIV-1 Env trimer with 3 PGV04 Fabs | Descriptor: | BG505 SOSIP gp120, BG505 SOSIP gp41, PGV04 heavy chain, ... | Authors: | Lyumkis, D, Julien, J.-P, Wilson, I.A, Ward, A.B. | Deposit date: | 2013-10-26 | Release date: | 2013-11-13 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (5.8 Å) | Cite: | Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer. Science, 342, 2013
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8ESU
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![BU of 8esu by Molmil](/molmil-images/mine/8esu) | Myoglobin variant Mb-imi complex | Descriptor: | IMIDAZOLE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Bacik, J.P, Fasan, R, Ando, N. | Deposit date: | 2022-10-14 | Release date: | 2023-12-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.04 Å) | Cite: | Mechanistic manifold in a hemoprotein-catalyzed cyclopropanation reaction with diazoketone. Nat Commun, 14, 2023
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8F78
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![BU of 8f78 by Molmil](/molmil-images/mine/8f78) | Compound 1 bound to procaspase-6 | Descriptor: | 5-fluoro-2-({[3-(pyrimidin-2-yl)pyridin-2-yl]amino}methyl)phenol, CHLORIDE ION, Procaspase-6 | Authors: | Fan, P, Zhao, Y, Renslo, A.R, Arkin, M.R. | Deposit date: | 2022-11-18 | Release date: | 2023-12-13 | Last modified: | 2024-06-26 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Systematic Study of Heteroarene Stacking Using a Congeneric Set of Molecular Glues for Procaspase-6. J.Med.Chem., 66, 2023
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7YW9
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![BU of 7yw9 by Molmil](/molmil-images/mine/7yw9) | Crystal structure of the triple mutant CmnC-L136Q,S138G,D249Y in complex with alpha-KG | Descriptor: | ACETATE ION, CmnC, D-ARGININE, ... | Authors: | Huang, S.J, Hsiao, Y.H, Lin, E.C, Hsiao, P.Y, Chang, C.Y. | Deposit date: | 2022-08-22 | Release date: | 2023-08-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal structure of the alpha-ketoglutarate-dependent non-heme iron oxygenase CmnC in capreomycin biosynthesis and its engineering to catalyze hydroxylation of the substrate enantiomer. Front Chem, 10, 2022
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6RM8
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![BU of 6rm8 by Molmil](/molmil-images/mine/6rm8) | Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Hamann, F, Neumann, P, Ficner, R. | Deposit date: | 2019-05-06 | Release date: | 2020-02-05 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2. Proc.Natl.Acad.Sci.USA, 117, 2020
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2SRT
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8EYP
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![BU of 8eyp by Molmil](/molmil-images/mine/8eyp) | Joint X-ray/neutron structure of Salmonella typhimurium tryptophan synthase internal aldimine from microgravity-grown crystal | Descriptor: | SODIUM ION, Tryptophan synthase alpha chain, Tryptophan synthase beta chain | Authors: | Drago, V.N, Kovalevsky, A, Blakeley, M.P, Forsyth, V.T, Mueser, T.C. | Deposit date: | 2022-10-28 | Release date: | 2024-02-14 | Last modified: | 2024-05-08 | Method: | NEUTRON DIFFRACTION (1.8 Å), X-RAY DIFFRACTION | Cite: | Neutron diffraction from a microgravity-grown crystal reveals the active site hydrogens of the internal aldimine form of tryptophan synthase. Cell Rep Phys Sci, 5, 2024
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5EYX
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![BU of 5eyx by Molmil](/molmil-images/mine/5eyx) | Monoclinic Form of Centrolobium tomentosum seed lectin (CTL) complexed with Man1-3Man-OMe. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Centrolobium tomentosum lectin, ... | Authors: | Almeida, A.C, Osterne, V.J.S, Santiago, M.Q, Pinto-Junior, V.R, Silva-Filho, J.C, Lossio, C.F, Almeida, R.P.H, Teixeira, C.S, Delatorre, P, Rocha, B.A.M, Santiago, K.S, Cavada, B.S. | Deposit date: | 2015-11-25 | Release date: | 2016-03-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural analysis of Centrolobium tomentosum seed lectin with inflammatory activity. Arch.Biochem.Biophys., 596, 2016
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6ED9
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6S7Q
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6RSC
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1JAB
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![BU of 1jab by Molmil](/molmil-images/mine/1jab) | TYPE III ANTIFREEZE PROTEIN ISOFORM HPLC 12 T18S | Descriptor: | PROTEIN (ANTIFREEZE PROTEIN TYPE III) | Authors: | Graether, S.P, Deluca, C.I, Baardsnes, J, Hill, G.A, Davies, P.L, Jia, Z. | Deposit date: | 1999-01-24 | Release date: | 1999-04-29 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Quantitative and qualitative analysis of type III antifreeze protein structure and function. J.Biol.Chem., 274, 1999
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8TDX
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![BU of 8tdx by Molmil](/molmil-images/mine/8tdx) | TRNM-b.01 in complex with HIV Env fusion peptide | Descriptor: | Env Fusion Peptide, TRNM-b.01 Fab Heavy Chain, TRNM-b.01 Fab Light Chain | Authors: | Olia, A.S, Kwong, P.D. | Deposit date: | 2023-07-05 | Release date: | 2024-07-10 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Broad and potent HIV-1 neutralization in fusion peptide-primed SHIV-boosted macaques To Be Published
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4Q78
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![BU of 4q78 by Molmil](/molmil-images/mine/4q78) | Structure-assisted design of carborane-based inhibitors of carbonic anhydrase | Descriptor: | 1-(sulfamoylamino)methyl-1,2-dicarba-closo-dodecaborane, Carbonic anhydrase 2, MERCURIBENZOIC ACID, ... | Authors: | Mader, P, Brynda, J, Rezacova, P. | Deposit date: | 2014-04-24 | Release date: | 2015-03-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Carborane-based carbonic anhydrase inhibitors: insight into CAII/CAIX specificity from a high-resolution crystal structure, modeling, and quantum chemical calculations. Biomed Res Int, 2014, 2014
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8TJP
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![BU of 8tjp by Molmil](/molmil-images/mine/8tjp) | KS-AT core of 6-deoxyerythronolide B synthase (DEBS) Module 3 crosslinked with its elongation ACP partner | Descriptor: | EryAII | Authors: | Cogan, D.P, Soohoo, A.M, Chen, M, Brodsky, K.L, Liu, Y, Khosla, C. | Deposit date: | 2023-07-23 | Release date: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.71 Å) | Cite: | Structural Basis for Intermodular Communication in Assembly-Line Polyketide Biosynthesis To Be Published
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8IM6
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![BU of 8im6 by Molmil](/molmil-images/mine/8im6) | Crystal structure of HCoV 229E main protease in complex with PF07304814 | Descriptor: | 3C-like proteinase, [(3~{S})-3-[[(2~{S})-2-[(4-methoxy-1~{H}-indol-2-yl)carbonylamino]-4-methyl-pentanoyl]amino]-2-oxidanylidene-4-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]butyl] dihydrogen phosphate | Authors: | Zhou, Y.R, Zeng, P, Zhang, J, Li, J. | Deposit date: | 2023-03-06 | Release date: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structural basis of main proteases of HCoV-229E bound to inhibitor PF-07304814 and PF-07321332. Biochem.Biophys.Res.Commun., 657, 2023
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4E7V
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![BU of 4e7v by Molmil](/molmil-images/mine/4e7v) | The structure of R6 bovine insulin | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Harris, P, Frankaer, C.G, Knudsen, M.V. | Deposit date: | 2012-03-19 | Release date: | 2012-04-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy. Acta Crystallogr.,Sect.D, 68, 2012
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6EEI
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![BU of 6eei by Molmil](/molmil-images/mine/6eei) | Crystal structure of Arabidopsis thaliana phenylacetaldehyde synthase in complex with L-phenylalanine | Descriptor: | PHENYLALANINE, SULFATE ION, Tyrosine decarboxylase 1 | Authors: | Torrens-Spence, M.P, Chiang, Y, Smith, T, Vicent, M.A, Wang, Y, Weng, J.K. | Deposit date: | 2018-08-14 | Release date: | 2018-09-19 | Last modified: | 2020-06-03 | Method: | X-RAY DIFFRACTION (1.99001348 Å) | Cite: | Structural basis for divergent and convergent evolution of catalytic machineries in plant aromatic amino acid decarboxylase proteins. Proc.Natl.Acad.Sci.USA, 117, 2020
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6RVD
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![BU of 6rvd by Molmil](/molmil-images/mine/6rvd) | Revised cryo-EM structure of the human 2:1 Ptch1-Shh complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | El Omari, K, Rudolf, A.F, Kowatsch, C, Malinauskas, T, Kinnebrew, M, Ansell, T.B, Bishop, B, Pardon, E, Schwab, R.A, Qian, M, Duman, R, Covey, D.F, Steyaert, J, Wagner, A, Sansom, M.S.P, Rohatgi, R, Siebold, C. | Deposit date: | 2019-05-31 | Release date: | 2019-10-02 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism. Nat.Chem.Biol., 15, 2019
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7Z3F
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![BU of 7z3f by Molmil](/molmil-images/mine/7z3f) | Crystal structure of the cupredoxin AcoP from Acidithiobacillus ferrooxidans, oxidized form | Descriptor: | ACETATE ION, AcoP, CHLORIDE ION, ... | Authors: | Leone, P, Sciara, G, Ilbert, M. | Deposit date: | 2022-03-02 | Release date: | 2023-09-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Beyond the coupled distortion model: structural analysis of the single domain cupredoxin AcoP, a green mononuclear copper centre with original features. Dalton Trans, 53, 2024
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4M7Z
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![BU of 4m7z by Molmil](/molmil-images/mine/4m7z) | Unliganded 1 crystal structure of S25-26 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Haji-Ghassemi, O, Evans, S.V, Muller-Loennies, S, Saldova, R, Muniyappa, M, Brade, L, Rudd, P.M, Harvey, D.J, Kosma, P, Brade, H. | Deposit date: | 2013-08-12 | Release date: | 2014-04-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Groove-type Recognition of Chlamydiaceae-specific Lipopolysaccharide Antigen by a Family of Antibodies Possessing an Unusual Variable Heavy Chain N-Linked Glycan. J.Biol.Chem., 289, 2014
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3K2L
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![BU of 3k2l by Molmil](/molmil-images/mine/3k2l) | Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) | Descriptor: | CHLORIDE ION, Dual specificity tyrosine-phosphorylation-regulated kinase 2, SODIUM ION, ... | Authors: | Filippakopoulos, P, Myrianthopoulos, V, Soundararajan, M, Krojer, T, Hapka, E, Fedorov, O, Berridge, G, Wang, J, Shrestha, L, Pike, A.C.W, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Bountra, C, Mikros, E, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-09-30 | Release date: | 2009-10-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition. Structure, 21, 2013
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