8HQE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hqe by Molmil](/molmil-images/mine/8hqe) | Cryo-EM structure of the apo-GPR132-Gi | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Wang, J.L, Ding, J.H, Sun, J.P, Yu, X. | 登録日 | 2022-12-13 | 公開日 | 2023-10-11 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Functional screening and rational design of compounds targeting GPR132 to treat diabetes. Nat Metab, 5, 2023
|
|
3PO6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3po6 by Molmil](/molmil-images/mine/3po6) | Crystal structure of human carbonic anhydrase II with 6,7-Dimethoxy-1-methyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide | 分子名称: | (1R)-6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide, (1S)-6,7-dimethoxy-1-methyl-3,4-dihydroisoquinoline-2(1H)-sulfonamide, ACETATE ION, ... | 著者 | Mader, P, Brynda, J, Gitto, R, Agnello, S, Ferro, S, De Luca, L, Vullo, D, Supuran, C.T, Chimirri, A. | 登録日 | 2010-11-22 | 公開日 | 2011-04-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Structural basis for the interaction between carbonic anhydrase and 1,2,3,4-tetrahydroisoquinolin-2-ylsulfonamides. J.Med.Chem., 54, 2011
|
|
4WOG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wog by Molmil](/molmil-images/mine/4wog) | Crystal Structure of Frutalin from Artocarpus incisa | 分子名称: | Frutalin | 著者 | Pereira, H.M, Moreira, A.C.O.M, Vieira Neto, A.E, Moreno, F.B.M.B, Lobo, M.D.P, Sousa, F.D, Grangeiro, T.B, Moreira, R.A. | 登録日 | 2014-10-15 | 公開日 | 2015-10-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.813 Å) | 主引用文献 | Crystal Structure of Frutalin from Artocarpus incisa To Be Published
|
|
4ZJ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zj3 by Molmil](/molmil-images/mine/4zj3) | Crystal structure of cephalexin bound acyl-enzyme intermediate of Val216AcrF mutant TEM1 beta-lactamase from Escherichia coli: E166N and V216AcrF mutant. | 分子名称: | Beta-lactamase TEM | 著者 | Xiao, H, Nasertorabi, F, Choi, S, Han, G.W, Reed, S.A, Stevens, R.C, Schultz, P.G. | 登録日 | 2015-04-29 | 公開日 | 2015-05-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Exploring the potential impact of an expanded genetic code on protein function. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
3EIK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3eik by Molmil](/molmil-images/mine/3eik) | |
4WF5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4wf5 by Molmil](/molmil-images/mine/4wf5) | Crystal structure of E.Coli DsbA soaked with compound 4 | 分子名称: | 1,2-ETHANEDIOL, 4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid, COPPER (II) ION, ... | 著者 | Adams, L.A, Sharma, P, Mohanty, B, Ilyichova, O.V, Mulcair, M.D, Williams, M.L, Gleeson, E.C, Totsika, M, Doak, B.C, Caria, S, Rimmer, K, Shouldice, S.R, Vazirani, M, Headey, S.J, Plumb, B.R, Martin, J.L, Heras, B, Simpson, J.S, Scanlon, M.J. | 登録日 | 2014-09-12 | 公開日 | 2015-01-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA. Angew.Chem.Int.Ed.Engl., 54, 2015
|
|
8HQM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hqm by Molmil](/molmil-images/mine/8hqm) | Activation mechanism of GPR132 by NPGLY | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Wang, J.L, Ding, J.H, Sun, J.P, Yu, X. | 登録日 | 2022-12-13 | 公開日 | 2023-10-11 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Functional screening and rational design of compounds targeting GPR132 to treat diabetes. Nat Metab, 5, 2023
|
|
3EJ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ej3 by Molmil](/molmil-images/mine/3ej3) | Structural and mechanistic analysis of trans-3-chloroacrylic acid dehalogenase activity | 分子名称: | ACETATE ION, Alpha-subunit of trans-3-chloroacrylic acid dehalogenase, Beta-subunit of trans-3-chloroacrylic acid dehalogenase, ... | 著者 | Pegan, S, Serrano, H, Whitman, C.P, Mesecar, A.D. | 登録日 | 2008-09-17 | 公開日 | 2008-12-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural and mechanistic analysis of trans-3-chloroacrylic acid dehalogenase activity. Acta Crystallogr.,Sect.D, 64, 2008
|
|
6XSD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xsd by Molmil](/molmil-images/mine/6xsd) | Patient-derived B2GPI | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-glycoprotein 1 | 著者 | Klenotic, P.A, Yu, E.W.Y. | 登録日 | 2020-07-15 | 公開日 | 2021-07-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | B2-Glycoprotein I and it's role in APS To Be Published
|
|
1AGT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1agt by Molmil](/molmil-images/mine/1agt) | SOLUTION STRUCTURE OF THE POTASSIUM CHANNEL INHIBITOR AGITOXIN 2: CALIPER FOR PROBING CHANNEL GEOMETRY | 分子名称: | AGITOXIN 2 | 著者 | Krezel, A.M, Kasibhatla, C, Hidalgo, P, Mackinnon, R, Wagner, G. | 登録日 | 1995-04-14 | 公開日 | 1995-07-10 | 最終更新日 | 2017-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the potassium channel inhibitor agitoxin 2: caliper for probing channel geometry. Protein Sci., 4, 1995
|
|
8HBG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8hbg by Molmil](/molmil-images/mine/8hbg) | FMDV (A/TUR/14/98) in complex with M678F | 分子名称: | M678F nab, VP1 of capsid protein, VP2 of capsid protein, ... | 著者 | Li, H.Z, Dong, H, Liu, P. | 登録日 | 2022-10-28 | 公開日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural and in vivo studies of neutralizing antibody topographical classifications reveal mechanisms underlying differences in immunogenicity and antigenicity between 146S and 12S of foot-and-mouth disease virus To Be Published
|
|
3PQ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pq5 by Molmil](/molmil-images/mine/3pq5) | Structure of I274C variant of E. coli KatE[] - Images 19-24 | 分子名称: | CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE 17R, 18S, ... | 著者 | Loewen, P.C, Jha, V, Louis, S, Chelikani, P, Carpena, X, Fita, I. | 登録日 | 2010-11-25 | 公開日 | 2010-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Modulation of heme orientation and binding by a single residue in catalase HPII of Escherichia coli. Biochemistry, 50, 2011
|
|
1WZ9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wz9 by Molmil](/molmil-images/mine/1wz9) | The 2.1 A structure of a tumour suppressing serpin | 分子名称: | Maspin precursor, SULFATE ION | 著者 | Law, R.H, Irving, J.A, Buckle, A.M, Ruzyla, K, Buzza, M, Bashtannyk-Puhalovich, T.A, Beddoe, T.C, Kim, N, Worrall, D.M, Bottomley, S.P, Bird, P.I, Rossjohn, J, Whisstock, J.C. | 登録日 | 2005-03-03 | 公開日 | 2005-03-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix. J.Biol.Chem., 280, 2005
|
|
6OMC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6omc by Molmil](/molmil-images/mine/6omc) | |
2LZW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lzw by Molmil](/molmil-images/mine/2lzw) | DNA duplex containing mispair-aligned O6G-heptylene-O6G interstrand cross-link | 分子名称: | DNA (5'-D(*CP*GP*AP*AP*AP*GP*TP*TP*TP*CP*G)-3'), HEPTANE | 著者 | Denisov, A.Y, McManus, F.P, Noronha, A.M, Wilds, C.J. | 登録日 | 2012-10-11 | 公開日 | 2013-10-16 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis of interstrand cross-link repair by O 6 -alkylguanine DNA alkyltransferase. Org.Biomol.Chem., 15, 2017
|
|
2BGU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2bgu by Molmil](/molmil-images/mine/2bgu) | CRYSTAL STRUCTURE OF THE DNA MODIFYING ENZYME BETA-GLUCOSYLTRANSFERASE IN THE PRESENCE AND ABSENCE OF THE SUBSTRATE URIDINE DIPHOSPHOGLUCOSE | 分子名称: | BETA-GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE | 著者 | Vrielink, A, Rueger, W, Driessen, H.P.C, Freemont, P.S. | 登録日 | 1994-06-09 | 公開日 | 1995-12-09 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of the DNA modifying enzyme beta-glucosyltransferase in the presence and absence of the substrate uridine diphosphoglucose. EMBO J., 13, 1994
|
|
6XST
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xst by Molmil](/molmil-images/mine/6xst) | |
1A9B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1a9b by Molmil](/molmil-images/mine/1a9b) | DECAMER-LIKE CONFORMATION OF A NANO-PEPTIDE BOUND TO HLA-B3501 DUE TO NONSTANDARD POSITIONING OF THE C-TERMINUS | 分子名称: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-35 B*3501 (ALPHA CHAIN), ... | 著者 | Menssen, R, Orth, P, Ziegler, A, Saenger, W. | 登録日 | 1998-04-03 | 公開日 | 1998-10-21 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Decamer-like conformation of a nona-peptide bound to HLA-B*3501 due to non-standard positioning of the C terminus. J.Mol.Biol., 285, 1999
|
|
2BJJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2bjj by Molmil](/molmil-images/mine/2bjj) | Structure of recombinant human lactoferrin produced in the milk of transgenic cows | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | 著者 | Thomassen, E.A.J, Van Veen, H.A, Van Berkel, P.H.C, Nuijens, J.H, Abrahams, J.P. | 登録日 | 2005-02-03 | 公開日 | 2005-08-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The Protein Structure of Recombinant Human Lactoferrin Produced in the Milk of Transgenic Cows Closely Matches the Structure of Human Milk-Derived Lactoferrin Transgenic Res., 14, 2005
|
|
1AN0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1an0 by Molmil](/molmil-images/mine/1an0) | CDC42HS-GDP COMPLEX | 分子名称: | CDC42HS-GDP, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Kongsaeree, P, Cerione, R, Clardy, J. | 登録日 | 1997-06-26 | 公開日 | 1999-01-13 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The Structure Determination of Cdc42Hs and Gdp Complex To be Published
|
|
3PUN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3pun by Molmil](/molmil-images/mine/3pun) | Crystal structure of P domain dimer of Norovirus VA207 with Lewis y tetrasaccharide | 分子名称: | Capsid, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose | 著者 | Chen, Y, Tan, M, Xia, M, Hao, N, Zhang, X.C, Huang, P, Jiang, X, Li, X, Rao, Z. | 登録日 | 2010-12-06 | 公開日 | 2011-08-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystallography of a Lewis-binding norovirus, elucidation of strain-specificity to the polymorphic human histo-blood group antigens Plos Pathog., 7, 2011
|
|
2C44
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2c44 by Molmil](/molmil-images/mine/2c44) | Crystal Structure of E. coli Tryptophanase | 分子名称: | POTASSIUM ION, SULFATE ION, TRYPTOPHANASE | 著者 | Ku, S.-Y, Yip, P, Howell, P.L. | 登録日 | 2005-10-15 | 公開日 | 2006-06-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of Escherichia Coli Tryptophanase Acta Crystallogr.,Sect.D, 62, 2006
|
|
5KJD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5kjd by Molmil](/molmil-images/mine/5kjd) | |
4ZQB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4zqb by Molmil](/molmil-images/mine/4zqb) | Crystal structure of NADP-dependent dehydrogenase from Rhodobactersphaeroides in complex with NADP and sulfate | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Kowiel, M, Gasiorowska, O.A, Shabalin, I.G, Handing, K.B, Porebski, P.J, Bonanno, J, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2015-05-08 | 公開日 | 2015-05-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of NADP-dependent dehydrogenase from Rhodobactersphaeroides in complex with NADP and sulfate to be published
|
|
5KK0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5kk0 by Molmil](/molmil-images/mine/5kk0) | Synechocystis ACO mutant - T136A | 分子名称: | Apocarotenoid-15,15'-oxygenase, CHLORIDE ION, FE (II) ION | 著者 | Sui, X, Kiser, P.D, Palczewski, K. | 登録日 | 2016-06-20 | 公開日 | 2016-07-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Utilization of Dioxygen by Carotenoid Cleavage Oxygenases. J.Biol.Chem., 290, 2015
|
|