8UOA
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![BU of 8uoa by Molmil](/molmil-images/mine/8uoa) | Structure of the synaptic vesicle protein 2A Luminal domain in complex with a nanobody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody, Synaptic vesicle glycoprotein 2A, ... | 著者 | Mittal, A, Martin, M.F, Levin, E, Adams, C, Yang, M, Ledecq, M, Horanyi, P.S, Coleman, J.A. | 登録日 | 2023-10-19 | 公開日 | 2024-05-22 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structures of synaptic vesicle protein 2A and 2B bound to anticonvulsants. Nat.Struct.Mol.Biol., 2024
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6MEG
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![BU of 6meg by Molmil](/molmil-images/mine/6meg) | Crystal structure of human monoclonal antibody HEPC46 | 分子名称: | antibody HEPC46 Heavy Chain, antibody HEPC46 Light Chain | 著者 | Flyak, A.I, Bjorkman, P.J. | 登録日 | 2018-09-06 | 公開日 | 2018-11-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design. Cell Host Microbe, 24, 2018
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8V4Q
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![BU of 8v4q by Molmil](/molmil-images/mine/8v4q) | Myxococcus xanthus EncA 3xHis pore mutant with tetrahedral symmetry | 分子名称: | Type 1 encapsulin shell protein EncA | 著者 | Szyszka, T.N, Andreas, M.P, Lie, F, Miller, L.M, Adamson, L.S.R, Fatehi, F, Twarock, R, Draper, B.E, Jarrold, M.F, Giessen, T.W, Lau, Y.H. | 登録日 | 2023-11-29 | 公開日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | 主引用文献 | Point mutation in a virus-like capsid drives symmetry reduction to form tetrahedral cages. Proc.Natl.Acad.Sci.USA, 121, 2024
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8U3E
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7XPE
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![BU of 7xpe by Molmil](/molmil-images/mine/7xpe) | Cryo-EM structure of the T=4 lake sinai virus 2 virus-like capsid at pH 8.5 | 分子名称: | Capsid protein alpha | 著者 | Chen, N.C, Wang, C.H, Chen, C.J, Yoshimura, M, Guan, H.H, Chuankhayan, P, Lin, C.C. | 登録日 | 2022-05-04 | 公開日 | 2023-02-08 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | Structures of honeybee-infecting Lake Sinai virus reveal domain functions and capsid assembly with dynamic motions. Nat Commun, 14, 2023
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6F2Q
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![BU of 6f2q by Molmil](/molmil-images/mine/6f2q) | Neutron crystal structure of perdeuterated galectin-3C in the ligand-free form | 分子名称: | Galectin-3 | 著者 | Manzoni, F, Blakeley, M.P, Oksanen, E, Logan, D.T. | 登録日 | 2017-11-27 | 公開日 | 2018-05-02 | 最終更新日 | 2024-05-01 | 実験手法 | NEUTRON DIFFRACTION (1.03 Å), X-RAY DIFFRACTION | 主引用文献 | Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design. J. Med. Chem., 61, 2018
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7XGZ
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![BU of 7xgz by Molmil](/molmil-images/mine/7xgz) | Cryo-EM structure of the T=4 lake sinai virus 2 virus-like capsid at pH 7.5 | 分子名称: | Capsid protein alpha | 著者 | Chen, N.C, Wang, C.H, Chen, C.J, Yoshimura, M, Guan, H.H, Chuankhayan, P, Lin, C.C. | 登録日 | 2022-04-07 | 公開日 | 2023-02-08 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | Structures of honeybee-infecting Lake Sinai virus reveal domain functions and capsid assembly with dynamic motions Nat Commun, 14, 2023
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5EL9
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![BU of 5el9 by Molmil](/molmil-images/mine/5el9) | A. thaliana IGPD2 in complex with the triazole-phosphonate inhibitor, (S)-C348, to 1.1A resolution | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Imidazoleglycerol-phosphate dehydratase 2, ... | 著者 | Bisson, C, Britton, K.L, Sedelnikova, S.E, Rodgers, H.F, Eadsforth, T.C, Viner, R.C, Hawkes, T.R, Baker, P.J, Rice, D.W. | 登録日 | 2015-11-04 | 公開日 | 2016-10-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Mirror-Image Packing Provides a Molecular Basis for the Nanomolar Equipotency of Enantiomers of an Experimental Herbicide. Angew.Chem.Int.Ed.Engl., 55, 2016
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7XPA
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![BU of 7xpa by Molmil](/molmil-images/mine/7xpa) | Cryo-EM structure of the T=3 lake sinai virus 2 virus-like capsid at pH 7.5 | 分子名称: | Capsid protein alpha | 著者 | Chen, N.C, Wang, C.H, Chen, C.J, Yoshimura, M, Guan, H.H, Chuankhayan, P, Lin, C.C. | 登録日 | 2022-05-04 | 公開日 | 2023-02-08 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Structures of honeybee-infecting Lake Sinai virus reveal domain functions and capsid assembly with dynamic motions. Nat Commun, 14, 2023
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7XPB
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![BU of 7xpb by Molmil](/molmil-images/mine/7xpb) | Cryo-EM structure of the T=4 lake sinai virus 2 virus-like capsid at pH 6.5 | 分子名称: | Capsid protein alpha | 著者 | Chen, N.C, Wang, C.H, Chen, C.J, Yoshimura, M, Guan, H.H, Chuankhayan, P, Lin, C.C. | 登録日 | 2022-05-04 | 公開日 | 2023-02-08 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | 主引用文献 | Structures of honeybee-infecting Lake Sinai virus reveal domain functions and capsid assembly with dynamic motions. Nat Commun, 14, 2023
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5EFV
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![BU of 5efv by Molmil](/molmil-images/mine/5efv) | The host-recognition device of Staphylococcus aureus phage Phi11 | 分子名称: | FE (III) ION, Phi ETA orf 56-like protein | 著者 | Koc, C, Kuhner, P, Xia, G, Spinelli, S, Roussel, A, Cambillau, C, Stehle, T. | 登録日 | 2015-10-26 | 公開日 | 2016-05-25 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the host-recognition device of Staphylococcus aureus phage 11. Sci Rep, 6, 2016
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5NJM
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![BU of 5njm by Molmil](/molmil-images/mine/5njm) | Lysozyme room-temperature structure determined by serial millisecond crystallography | 分子名称: | Lysozyme C | 著者 | Weinert, T, Vera, L, Marsh, M, James, D, Gashi, D, Nogly, P, Jaeger, K, Standfuss, J. | 登録日 | 2017-03-29 | 公開日 | 2017-09-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons. Nat Commun, 8, 2017
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8BXP
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8U3D
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6HV2
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![BU of 6hv2 by Molmil](/molmil-images/mine/6hv2) | MMP-13 in complex with the peptide IMISF | 分子名称: | CALCIUM ION, Collagenase 3, GLYCEROL, ... | 著者 | Mittl, P, Riedl, R, Hohl, D. | 登録日 | 2018-10-10 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.709 Å) | 主引用文献 | Drug Design Inspired by Nature: Crystallographic Detection of an Auto-Tailored Protease Inhibitor Template. Angew.Chem.Int.Ed.Engl., 58, 2019
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4QGO
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![BU of 4qgo by Molmil](/molmil-images/mine/4qgo) | Crystal structure of NucA from Streptococcus agalactiae with no metal bound | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DNA-entry nuclease (Competence-specific nuclease), ... | 著者 | Pedersen, L.C, Moon, A.F, Gaudu, P. | 登録日 | 2014-05-23 | 公開日 | 2014-11-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural characterization of the virulence factor nuclease A from Streptococcus agalactiae. Acta Crystallogr.,Sect.D, 70, 2014
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7XF3
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![BU of 7xf3 by Molmil](/molmil-images/mine/7xf3) | The structure of HLA-B*1501/BM58-66AF9 | 分子名称: | 9-mer peptide from Matrix protein 1, Beta-2-microglobulin, MHC class I antigen | 著者 | Zhao, Y.Z, Xiao, W.L, Wu, Y.N, Fan, W.F, Yue, C, Zhang, Q.X, Zhang, D.N, Yuan, X.J, Yao, S.J, Liu, S, Li, M, Wang, P.Y, Zhang, H.J, Zhang, J, Zhao, M, Zheng, X.Q, Liu, W.J, Gao, G.F, Liu, W.L. | 登録日 | 2022-03-31 | 公開日 | 2023-02-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Parallel T Cell Immunogenic Regions in Influenza B and A Viruses with Distinct Nuclear Export Signal Functions: The Balance between Viral Life Cycle and Immune Escape. J Immunol., 210, 2023
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6VL1
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![BU of 6vl1 by Molmil](/molmil-images/mine/6vl1) | Crystal Structure of the N-prenyltransferase DabA in Complex with NGG and Mg2+ | 分子名称: | DabA, MAGNESIUM ION, N-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-L-glutamic acid | 著者 | Chekan, J.R, Noel, J.P, Moore, B.S. | 登録日 | 2020-01-22 | 公開日 | 2020-04-08 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Algal neurotoxin biosynthesis repurposes the terpene cyclase structural fold into anN-prenyltransferase. Proc.Natl.Acad.Sci.USA, 117, 2020
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5EP5
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3R2H
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![BU of 3r2h by Molmil](/molmil-images/mine/3r2h) | 1.7 A resolution structure of As-Isolated FtnA from Pseudomonas aeruginosa (pH 10.5) | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Bacterioferritin, SODIUM ION | 著者 | Lovell, S.W, Battaile, K.P, Yao, H, Jepkorir, G, Nama, P.V, Weeratunga, S, Rivera, M. | 登録日 | 2011-03-14 | 公開日 | 2011-05-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Two distinct ferritin-like molecules in Pseudomonas aeruginosa: the product of the bfrA gene is a bacterial ferritin (FtnA) and not a bacterioferritin (Bfr). Biochemistry, 50, 2011
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8U3G
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3FRL
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![BU of 3frl by Molmil](/molmil-images/mine/3frl) | The 2.25 A crystal structure of LipL32, the major surface antigen of Leptospira interrogans serovar Copenhageni | 分子名称: | 2,2',2''-NITRILOTRIETHANOL, CHLORIDE ION, LipL32, ... | 著者 | Farah, C.S, Guzzo, C.R, Hauk, P, Ho, P.L. | 登録日 | 2009-01-08 | 公開日 | 2009-06-16 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure and calcium-binding activity of LipL32, the major surface antigen of pathogenic Leptospira sp. J.Mol.Biol., 390, 2009
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5FYY
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![BU of 5fyy by Molmil](/molmil-images/mine/5fyy) | Crystal structure of the catalytic domain of human JARID1B in complex with Maybridge fragment 3-pyridin-3-ylaniline (N05798a) (ligand modelled based on PANDDA event map) | 分子名称: | 1,2-ETHANEDIOL, 3-(pyridin-3-yl)aniline, CHLORIDE ION, ... | 著者 | Nowak, R, Krojer, T, Johansson, C, Gileadi, C, Kupinska, K, Strain-Damerell, C, Szykowska, A, Pearce, N, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, von Delft, F, Brennan, P.E, Oppermann, U. | 登録日 | 2016-03-10 | 公開日 | 2016-03-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Crystal Structure of the Catalytic Domain of Human Jarid1B in Complex with N05798A To be Published
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4GW8
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![BU of 4gw8 by Molmil](/molmil-images/mine/4gw8) | Human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and Leucettine L41 | 分子名称: | 1,2-ETHANEDIOL, 5-(1,3-benzodioxol-5-ylmethyl)-2-(phenylamino)-4H-imidazol-4-one, Consensus peptide (Pimtide), ... | 著者 | Filippakopoulos, P, Bullock, A, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Meijer, L, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2012-09-01 | 公開日 | 2012-10-03 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Selectivity, cocrystal structures, and neuroprotective properties of leucettines, a family of protein kinase inhibitors derived from the marine sponge alkaloid leucettamine B. J.Med.Chem., 55, 2012
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6MCX
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![BU of 6mcx by Molmil](/molmil-images/mine/6mcx) | INFLUENZA VIRUS NEURAMINIDASE SUBTYPE N9 (TERN) RECOMBINANT HEAD DOMAIN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | 著者 | Streltsov, V.A, Schmidt, P, McKimm-Breschkin, J. | 登録日 | 2018-09-02 | 公開日 | 2019-01-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of an Influenza A virus N9 neuraminidase with a tetrabrachion-domain stalk. Acta Crystallogr.,Sect.F, 75, 2019
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